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Found 17 of ic50 for UniProtKB: Q8IY84
TargetSerine/threonine-protein kinase NIM1(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  91.5nMAssay Description:Inhibition of human NIM1 using KKKVSRSGLYRSPSMPENLNRPR as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase NIM1(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  129nMAssay Description:Inhibition of human NIM1 using KKKVSRSGLYRSPSMPENLNRPR as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase NIM1(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50585188(CHEMBL5086901)
Affinity DataIC50:  4.40E+3nMAssay Description:Inhibition of full length recombinant human NIM1 using KKKVSRSGLYRSPSMPENLNRPR as substrate incubated for 40 mins in presence of [gamma-33P-ATP] by r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase NIM1(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50048362(CHEMBL3309995)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of NIM1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase NIM1(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50048364(CHEMBL3309997)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of NIM1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase NIM1(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50048365(CHEMBL3309998)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of NIM1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase NIM1(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50048374(CHEMBL3310151)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of NIM1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase NIM1(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM138348(US8877944, 99)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human NIM1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase NIM1(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM158154(US10081622, Compound 11 | US10370379, Entrectinib ...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of NIM1 (unknown origin) in presence of gamma33-ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase NIM1(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50327912(3-(4-Morpholin-4-yl-benzoylamino)-1H-thieno[3,2-c]...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of NIM1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase NIM1(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50343559(1-(2-HYDROXYETHYL)-8-[[5-(4-METHYLPIPERAZIN-1-YL)-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of NIM1 assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase NIM1(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM27344(2-(pyridin-4-yl)-1H,4H,5H,6H,7H-pyrrolo[3,2-c]pyri...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of NIM1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase NIM1(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50519662(CHEMBL4438748)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant full length human NIM1 using KKKVSRSGLYRSP as substrate measured after 40 mins in presence of [gamma33P]ATP by radiometric ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase NIM1(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50048357(CHEMBL3309990)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of NIM1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase NIM1(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50329427(5-(2-Amino-pyrimidin-4-yl)-2-phenyl-1H-pyrrole-3-c...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of NIM1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase NIM1(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50021626(CHEMBL3298400)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of NIM1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase NIM1(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50021618(CHEMBL3297762 | US9145418, 2)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of NIM1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed