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Compile Data Set for Download or QSAR

Found 27 hits of ki data for polymerid = 50003912,50005674,50006901,8398   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Low molecular weight phosphotyrosine protein phosphatase (LMWPTP)


(Homo sapiens (Human))
BDBM50256796
PNG
(6,7-Dihydroxy-2-(4'-hydroxyphenyl)-3-[(1,1'-biphen...)
Show SMILES Oc1ccc(cc1)-c1oc2cc(O)c(O)cc2c(=O)c1Cc1ccc(cc1)-c1ccccc1
Show InChI InChI=1S/C28H20O5/c29-21-12-10-20(11-13-21)28-23(27(32)22-15-24(30)25(31)16-26(22)33-28)14-17-6-8-19(9-7-17)18-4-2-1-3-5-18/h1-13,15-16,29-31H,14H2
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270n/an/an/an/an/an/an/an/a



University of Modena and R.E.

Curated by ChEMBL


Assay Description
Inhibition of human cloned LMW-PTP isoform 1 expressed in Escherichia coli TB1 by competitive inhibition assay


Bioorg Med Chem 17: 2658-72 (2009)


Article DOI: 10.1016/j.bmc.2009.02.060
BindingDB Entry DOI: 10.7270/Q2K0745F
More data for this
Ligand-Target Pair
Low molecular weight phosphotyrosine protein phosphatase (LMWPTP)


(Homo sapiens (Human))
BDBM50256796
PNG
(6,7-Dihydroxy-2-(4'-hydroxyphenyl)-3-[(1,1'-biphen...)
Show SMILES Oc1ccc(cc1)-c1oc2cc(O)c(O)cc2c(=O)c1Cc1ccc(cc1)-c1ccccc1
Show InChI InChI=1S/C28H20O5/c29-21-12-10-20(11-13-21)28-23(27(32)22-15-24(30)25(31)16-26(22)33-28)14-17-6-8-19(9-7-17)18-4-2-1-3-5-18/h1-13,15-16,29-31H,14H2
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340n/an/an/an/an/an/an/an/a



University of Modena and R.E.

Curated by ChEMBL


Assay Description
Inhibition of human cloned LMW-PTP isoform 2 expressed in Escherichia coli TB1 by competitive inhibition assay


Bioorg Med Chem 17: 2658-72 (2009)


Article DOI: 10.1016/j.bmc.2009.02.060
BindingDB Entry DOI: 10.7270/Q2K0745F
More data for this
Ligand-Target Pair
Low molecular weight phosphotyrosine protein phosphatase (LMWPTP)


(Homo sapiens (Human))
BDBM199180
PNG
(US9217012, 10)
Show SMILES CCc1ccc(cc1)C(=O)NCCCCC(NC(=O)C(Cc1ccc(cc1)C(F)(F)P(O)(O)=O)NC(=O)C(Cc1ccccc1)NC(=O)COC1CC(C)CCC1C(C)C)C(N)=O
Show InChI InChI=1S/C46H62F2N5O9P/c1-5-31-15-19-34(20-16-31)43(56)50-24-10-9-13-37(42(49)55)52-45(58)39(27-33-17-21-35(22-18-33)46(47,48)63(59,60)61)53-44(57)38(26-32-11-7-6-8-12-32)51-41(54)28-62-40-25-30(4)14-23-36(40)29(2)3/h6-8,11-12,15-22,29-30,36-40H,5,9-10,13-14,23-28H2,1-4H3,(H2,49,55)(H,50,56)(H,51,54)(H,52,58)(H,53,57)(H2,59,60,61)
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US Patent
>1.00E+3>-8.18n/an/an/an/an/a7.025



Indiana University Research and Technology Corporation

US Patent


Assay Description
PTP activity was assayed using p-nitrophenyl phosphate (pNPP) as a substrate in DMG buffer (50 mM DMG, pH 7.0, 1 mM EDTA, 150 mM NaCl, 2 mM DTT, 0.1 ...


US Patent US9217012 (2015)


BindingDB Entry DOI: 10.7270/Q2FX788H
More data for this
Ligand-Target Pair
Low molecular weight phosphotyrosine protein phosphatase (LMWPTP)


(Homo sapiens (Human))
BDBM50257418
PNG
(7-Hydroxy-2-(4'-hydroxyphenyl)-3-[(3'',4''-dihydro...)
Show SMILES Oc1ccc(cc1)-c1oc2cc(O)ccc2c(=O)c1Cc1ccc(cc1)-c1ccc(O)c(O)c1
Show InChI InChI=1S/C28H20O6/c29-20-8-5-18(6-9-20)28-23(27(33)22-11-10-21(30)15-26(22)34-28)13-16-1-3-17(4-2-16)19-7-12-24(31)25(32)14-19/h1-12,14-15,29-32H,13H2
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2.23E+3n/an/an/an/an/an/an/an/a



University of Modena and R.E.

Curated by ChEMBL


Assay Description
Inhibition of human cloned LMW-PTP isoform 1 expressed in Escherichia coli TB1 by mixed type inhibition assay


Bioorg Med Chem 17: 2658-72 (2009)


Article DOI: 10.1016/j.bmc.2009.02.060
BindingDB Entry DOI: 10.7270/Q2K0745F
More data for this
Ligand-Target Pair
Low molecular weight phosphotyrosine protein phosphatase (LMWPTP)


(Homo sapiens (Human))
BDBM50257294
PNG
(7-Hydroxy-2-(4'-hydroxyphenyl)-3-[(1,1'-biphenyl-4...)
Show SMILES Oc1ccc(cc1)-c1oc2cc(O)ccc2c(=O)c1Cc1ccc(cc1)-c1ccccc1
Show InChI InChI=1S/C28H20O4/c29-22-12-10-21(11-13-22)28-25(27(31)24-15-14-23(30)17-26(24)32-28)16-18-6-8-20(9-7-18)19-4-2-1-3-5-19/h1-15,17,29-30H,16H2
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2.50E+3n/an/an/an/an/an/an/an/a



University of Modena and R.E.

Curated by ChEMBL


Assay Description
Inhibition of human cloned LMW-PTP isoform 1 expressed in Escherichia coli TB1 by mixed type inhibition assay


Bioorg Med Chem 17: 2658-72 (2009)


Article DOI: 10.1016/j.bmc.2009.02.060
BindingDB Entry DOI: 10.7270/Q2K0745F
More data for this
Ligand-Target Pair
Low molecular weight phosphotyrosine protein phosphatase (LMWPTP)


(Homo sapiens (Human))
BDBM50257418
PNG
(7-Hydroxy-2-(4'-hydroxyphenyl)-3-[(3'',4''-dihydro...)
Show SMILES Oc1ccc(cc1)-c1oc2cc(O)ccc2c(=O)c1Cc1ccc(cc1)-c1ccc(O)c(O)c1
Show InChI InChI=1S/C28H20O6/c29-20-8-5-18(6-9-20)28-23(27(33)22-11-10-21(30)15-26(22)34-28)13-16-1-3-17(4-2-16)19-7-12-24(31)25(32)14-19/h1-12,14-15,29-32H,13H2
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2.68E+3n/an/an/an/an/an/an/an/a



University of Modena and R.E.

Curated by ChEMBL


Assay Description
Inhibition of human cloned LMW-PTP isoform 2 expressed in Escherichia coli TB1 by mixed type inhibition assay


Bioorg Med Chem 17: 2658-72 (2009)


Article DOI: 10.1016/j.bmc.2009.02.060
BindingDB Entry DOI: 10.7270/Q2K0745F
More data for this
Ligand-Target Pair
Low molecular weight phosphotyrosine protein phosphatase (LMWPTP)


(Homo sapiens (Human))
BDBM50257294
PNG
(7-Hydroxy-2-(4'-hydroxyphenyl)-3-[(1,1'-biphenyl-4...)
Show SMILES Oc1ccc(cc1)-c1oc2cc(O)ccc2c(=O)c1Cc1ccc(cc1)-c1ccccc1
Show InChI InChI=1S/C28H20O4/c29-22-12-10-21(11-13-22)28-25(27(31)24-15-14-23(30)17-26(24)32-28)16-18-6-8-20(9-7-18)19-4-2-1-3-5-19/h1-15,17,29-30H,16H2
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7.80E+3n/an/an/an/an/an/an/an/a



University of Modena and R.E.

Curated by ChEMBL


Assay Description
Inhibition of human cloned LMW-PTP isoform 2 expressed in Escherichia coli TB1 by mixed type inhibition assay


Bioorg Med Chem 17: 2658-72 (2009)


Article DOI: 10.1016/j.bmc.2009.02.060
BindingDB Entry DOI: 10.7270/Q2K0745F
More data for this
Ligand-Target Pair
Low molecular weight phosphotyrosine protein phosphatase


(Bos taurus)
BDBM50371120
PNG
(CHEMBL242173)
Show SMILES OC(=O)c1ccc2NC(C3CC=CC3c2c1)c1cccc(Br)c1
Show InChI InChI=1S/C19H16BrNO2/c20-13-4-1-3-11(9-13)18-15-6-2-5-14(15)16-10-12(19(22)23)7-8-17(16)21-18/h1-5,7-10,14-15,18,21H,6H2,(H,22,23)
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9.00E+3n/an/an/an/an/an/an/an/a



Institute for Research in Biomedicine (IRB)

Curated by ChEMBL


Assay Description
Inhibition of bovine low molecular weight PTP expressed in Escherichia coli BL21(D3) cells


Eur J Med Chem 42: 1102-8 (2007)


Article DOI: 10.1016/j.ejmech.2007.01.017
BindingDB Entry DOI: 10.7270/Q27W6D1F
More data for this
Ligand-Target Pair
Low molecular weight phosphotyrosine protein phosphatase


(Bos taurus)
BDBM50371127
PNG
(CHEMBL244681)
Show SMILES OC(=O)c1ccc(cc1)-n1cccc1CC1=NC(=O)NC1=O
Show InChI InChI=1S/C15H11N3O4/c19-13-12(16-15(22)17-13)8-11-2-1-7-18(11)10-5-3-9(4-6-10)14(20)21/h1-7H,8H2,(H,20,21)(H,17,19,22)
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1.10E+4n/an/an/an/an/an/an/an/a



Institute for Research in Biomedicine (IRB)

Curated by ChEMBL


Assay Description
Inhibition of bovine low molecular weight PTP expressed in Escherichia coli BL21(D3) cells


Eur J Med Chem 42: 1102-8 (2007)


Article DOI: 10.1016/j.ejmech.2007.01.017
BindingDB Entry DOI: 10.7270/Q27W6D1F
More data for this
Ligand-Target Pair
Low molecular weight phosphotyrosine protein phosphatase (LMWPTP)


(Homo sapiens (Human))
BDBM50312261
PNG
((4-(4-bromo-3,5-bis(trifluoromethyl)phenylcarbamoy...)
Show SMILES OP(O)(=O)C(F)(F)c1ccc(cc1)C(=O)Nc1cc(c(Br)c(c1)C(F)(F)F)C(F)(F)F
Show InChI InChI=1S/C16H9BrF8NO4P/c17-12-10(14(18,19)20)5-9(6-11(12)15(21,22)23)26-13(27)7-1-3-8(4-2-7)16(24,25)31(28,29)30/h1-6H,(H,26,27)(H2,28,29,30)
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1.48E+4n/an/an/an/an/an/an/an/a



University of California

Curated by ChEMBL


Assay Description
Inhibition of human HCPTPA


Bioorg Med Chem Lett 19: 6851-4 (2009)


Article DOI: 10.1016/j.bmcl.2009.10.090
BindingDB Entry DOI: 10.7270/Q21G0MDK
More data for this
Ligand-Target Pair
Low molecular weight phosphotyrosine protein phosphatase


(Mus musculus)
BDBM50096252
PNG
(CHEMBL3594198)
Show SMILES OP(O)(=O)Cc1ccc(CCl)cc1
Show InChI InChI=1S/C36H62N4O6/c1-5-8-9-10-11-12-13-15-21-28(42)25-30-34(44)39-32(26(4)6-2)36(46)40-24-19-18-23-31(40)35(45)37-29(33(43)38-30)22-17-14-16-20-27(41)7-3/h26,29-32H,5-25H2,1-4H3,(H,37,45)(H,38,43)(H,39,44)/t26?,29-,30-,31+,32-/m0/s1
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4.70E+4n/an/an/an/an/an/an/an/a



University of Campinas

Curated by ChEMBL


Assay Description
Competitive inhibition of mouse LMW-PTP expressed in Escherichia coli using pNPP substrate by Dixon plot


Bioorg Med Chem 23: 4462-71 (2015)


Article DOI: 10.1016/j.bmc.2015.06.017
BindingDB Entry DOI: 10.7270/Q2R78GZ7
More data for this
Ligand-Target Pair
Low molecular weight phosphotyrosine protein phosphatase


(Bos taurus)
BDBM50371125
PNG
(CHEMBL244088)
Show SMILES OC(=O)c1ccc2NC(C3CC=CC3c2c1)c1ccccc1C(F)(F)F
Show InChI InChI=1S/C20H16F3NO2/c21-20(22,23)16-7-2-1-4-14(16)18-13-6-3-5-12(13)15-10-11(19(25)26)8-9-17(15)24-18/h1-5,7-10,12-13,18,24H,6H2,(H,25,26)
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5.00E+4n/an/an/an/an/an/an/an/a



Institute for Research in Biomedicine (IRB)

Curated by ChEMBL


Assay Description
Inhibition of bovine low molecular weight PTP expressed in Escherichia coli BL21(D3) cells


Eur J Med Chem 42: 1102-8 (2007)


Article DOI: 10.1016/j.ejmech.2007.01.017
BindingDB Entry DOI: 10.7270/Q27W6D1F
More data for this
Ligand-Target Pair
Low molecular weight phosphotyrosine protein phosphatase


(Bos taurus)
BDBM50371131
PNG
(CHEMBL390874)
Show SMILES OC(=O)Cc1ccc2c(c1)[nH]c1ccc(Br)cc21
Show InChI InChI=1S/C14H10BrNO2/c15-9-2-4-12-11(7-9)10-3-1-8(6-14(17)18)5-13(10)16-12/h1-5,7,16H,6H2,(H,17,18)
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6.00E+4n/an/an/an/an/an/an/an/a



Institute for Research in Biomedicine (IRB)

Curated by ChEMBL


Assay Description
Inhibition of bovine low molecular weight PTP expressed in Escherichia coli BL21(D3) cells


Eur J Med Chem 42: 1102-8 (2007)


Article DOI: 10.1016/j.ejmech.2007.01.017
BindingDB Entry DOI: 10.7270/Q27W6D1F
More data for this
Ligand-Target Pair
Low molecular weight phosphotyrosine protein phosphatase


(Mus musculus)
BDBM50096253
PNG
(CHEMBL3593255)
Show SMILES OP(O)(=O)Cc1ccc(cc1)[N+]([O-])=O
Show InChI InChI=1S/C35H49N5O7/c1-4-22(3)31-35(47)40-18-12-11-17-29(40)34(46)36-26(15-8-6-7-13-24(41)5-2)32(44)37-27(33(45)38-31)19-23-20-39(21-30(42)43)28-16-10-9-14-25(23)28/h9-10,14,16,20,22,26-27,29,31H,4-8,11-13,15,17-19,21H2,1-3H3,(H,36,46)(H,37,44)(H,38,45)(H,42,43)/t22?,26-,27-,29+,31-/m0/s1
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1.24E+5n/an/an/an/an/an/an/an/a



University of Campinas

Curated by ChEMBL


Assay Description
Competitive inhibition of mouse LMW-PTP expressed in Escherichia coli using pNPP substrate by Dixon plot


Bioorg Med Chem 23: 4462-71 (2015)


Article DOI: 10.1016/j.bmc.2015.06.017
BindingDB Entry DOI: 10.7270/Q2R78GZ7
More data for this
Ligand-Target Pair
Low molecular weight phosphotyrosine protein phosphatase


(Bos taurus)
BDBM50371118
PNG
(CHEMBL244693)
Show SMILES CCn1c2ccc(CC(O)=O)cc2c2cc(CC(O)=O)ccc12
Show InChI InChI=1S/C18H17NO4/c1-2-19-15-5-3-11(9-17(20)21)7-13(15)14-8-12(10-18(22)23)4-6-16(14)19/h3-8H,2,9-10H2,1H3,(H,20,21)(H,22,23)
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1.70E+5n/an/an/an/an/an/an/an/a



Institute for Research in Biomedicine (IRB)

Curated by ChEMBL


Assay Description
Inhibition of bovine low molecular weight PTP expressed in Escherichia coli BL21(D3) cells


Eur J Med Chem 42: 1102-8 (2007)


Article DOI: 10.1016/j.ejmech.2007.01.017
BindingDB Entry DOI: 10.7270/Q27W6D1F
More data for this
Ligand-Target Pair
Low molecular weight phosphotyrosine protein phosphatase


(Bos taurus)
BDBM50371123
PNG
(CHEMBL244090)
Show SMILES OC(=O)c1ccc2[nH]c3CCSCc3c2c1
Show InChI InChI=1S/C12H11NO2S/c14-12(15)7-1-2-10-8(5-7)9-6-16-4-3-11(9)13-10/h1-2,5,13H,3-4,6H2,(H,14,15)
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2.40E+5n/an/an/an/an/an/an/an/a



Institute for Research in Biomedicine (IRB)

Curated by ChEMBL


Assay Description
Inhibition of bovine low molecular weight PTP expressed in Escherichia coli BL21(D3) cells


Eur J Med Chem 42: 1102-8 (2007)


Article DOI: 10.1016/j.ejmech.2007.01.017
BindingDB Entry DOI: 10.7270/Q27W6D1F
More data for this
Ligand-Target Pair
Low molecular weight phosphotyrosine protein phosphatase


(Bos taurus)
BDBM38435
PNG
(9-ethyl-1-oxo-2,3,4,9-tetrahydro-1H-carbazole-6-ca...)
Show SMILES CCn1c2c(CCCC2=O)c2cc(ccc12)C(O)=O
Show InChI InChI=1S/C15H15NO3/c1-2-16-12-7-6-9(15(18)19)8-11(12)10-4-3-5-13(17)14(10)16/h6-8H,2-5H2,1H3,(H,18,19)
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6.10E+5n/an/an/an/an/an/an/an/a



Institute for Research in Biomedicine (IRB)

Curated by ChEMBL


Assay Description
Inhibition of bovine low molecular weight PTP expressed in Escherichia coli BL21(D3) cells


Eur J Med Chem 42: 1102-8 (2007)


Article DOI: 10.1016/j.ejmech.2007.01.017
BindingDB Entry DOI: 10.7270/Q27W6D1F
More data for this
Ligand-Target Pair
Low molecular weight phosphotyrosine protein phosphatase


(Bos taurus)
BDBM50371126
PNG
(CHEMBL438508)
Show SMILES OC(=O)Cc1ccc(cc1)C1C(=S)NC2C=CSC2C1=O
Show InChI InChI=1S/C15H13NO3S2/c17-11(18)7-8-1-3-9(4-2-8)12-13(19)14-10(5-6-21-14)16-15(12)20/h1-6,10,12,14H,7H2,(H,16,20)(H,17,18)
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8.80E+5n/an/an/an/an/an/an/an/a



Institute for Research in Biomedicine (IRB)

Curated by ChEMBL


Assay Description
Inhibition of bovine low molecular weight PTP expressed in Escherichia coli BL21(D3) cells


Eur J Med Chem 42: 1102-8 (2007)


Article DOI: 10.1016/j.ejmech.2007.01.017
BindingDB Entry DOI: 10.7270/Q27W6D1F
More data for this
Ligand-Target Pair
Low molecular weight phosphotyrosine protein phosphatase


(Bos taurus)
BDBM50371130
PNG
(CHEMBL390873)
Show SMILES OC(=O)c1ccc(cc1)C1Nc2c(F)cc(F)cc2C2C=CCC12
Show InChI InChI=1S/C19H15F2NO2/c20-12-8-15-13-2-1-3-14(13)17(22-18(15)16(21)9-12)10-4-6-11(7-5-10)19(23)24/h1-2,4-9,13-14,17,22H,3H2,(H,23,24)
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9.10E+5n/an/an/an/an/an/an/an/a



Institute for Research in Biomedicine (IRB)

Curated by ChEMBL


Assay Description
Inhibition of bovine low molecular weight PTP expressed in Escherichia coli BL21(D3) cells


Eur J Med Chem 42: 1102-8 (2007)


Article DOI: 10.1016/j.ejmech.2007.01.017
BindingDB Entry DOI: 10.7270/Q27W6D1F
More data for this
Ligand-Target Pair
Low molecular weight phosphotyrosine protein phosphatase


(Bos taurus)
BDBM50371124
PNG
(CHEMBL244694)
Show SMILES Cn1c2ccccc2c2ccc(CC(O)=O)cc12
Show InChI InChI=1S/C15H13NO2/c1-16-13-5-3-2-4-11(13)12-7-6-10(8-14(12)16)9-15(17)18/h2-8H,9H2,1H3,(H,17,18)
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>1.00E+6n/an/an/an/an/an/an/an/a



Institute for Research in Biomedicine (IRB)

Curated by ChEMBL


Assay Description
Inhibition of bovine low molecular weight PTP expressed in Escherichia coli BL21(D3) cells


Eur J Med Chem 42: 1102-8 (2007)


Article DOI: 10.1016/j.ejmech.2007.01.017
BindingDB Entry DOI: 10.7270/Q27W6D1F
More data for this
Ligand-Target Pair
Low molecular weight phosphotyrosine protein phosphatase


(Bos taurus)
BDBM50371121
PNG
(CHEMBL440951)
Show SMILES OC(=O)c1ccc(cc1)-n1nc(c2CCCCc12)C(F)(F)F
Show InChI InChI=1S/C15H13F3N2O2/c16-15(17,18)13-11-3-1-2-4-12(11)20(19-13)10-7-5-9(6-8-10)14(21)22/h5-8H,1-4H2,(H,21,22)
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>1.00E+6n/an/an/an/an/an/an/an/a



Institute for Research in Biomedicine (IRB)

Curated by ChEMBL


Assay Description
Inhibition of bovine low molecular weight PTP expressed in Escherichia coli BL21(D3) cells


Eur J Med Chem 42: 1102-8 (2007)


Article DOI: 10.1016/j.ejmech.2007.01.017
BindingDB Entry DOI: 10.7270/Q27W6D1F
More data for this
Ligand-Target Pair
Low molecular weight phosphotyrosine protein phosphatase


(Bos taurus)
BDBM50371119
PNG
(CHEMBL244696)
Show SMILES OC(=O)c1ccc2NC(C3CC=CC3c2c1)c1cccnc1
Show InChI InChI=1S/C18H16N2O2/c21-18(22)11-6-7-16-15(9-11)13-4-1-5-14(13)17(20-16)12-3-2-8-19-10-12/h1-4,6-10,13-14,17,20H,5H2,(H,21,22)
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>1.00E+6n/an/an/an/an/an/an/an/a



Institute for Research in Biomedicine (IRB)

Curated by ChEMBL


Assay Description
Inhibition of bovine low molecular weight PTP expressed in Escherichia coli BL21(D3) cells


Eur J Med Chem 42: 1102-8 (2007)


Article DOI: 10.1016/j.ejmech.2007.01.017
BindingDB Entry DOI: 10.7270/Q27W6D1F
More data for this
Ligand-Target Pair
Low molecular weight phosphotyrosine protein phosphatase


(Bos taurus)
BDBM50371117
PNG
(CHEMBL242146)
Show SMILES OC(=O)CCC(=O)N1N=C(CC1c1ccccc1F)c1ccccc1
Show InChI InChI=1S/C19H17FN2O3/c20-15-9-5-4-8-14(15)17-12-16(13-6-2-1-3-7-13)21-22(17)18(23)10-11-19(24)25/h1-9,17H,10-12H2,(H,24,25)
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Institute for Research in Biomedicine (IRB)

Curated by ChEMBL


Assay Description
Inhibition of bovine low molecular weight PTP expressed in Escherichia coli BL21(D3) cells


Eur J Med Chem 42: 1102-8 (2007)


Article DOI: 10.1016/j.ejmech.2007.01.017
BindingDB Entry DOI: 10.7270/Q27W6D1F
More data for this
Ligand-Target Pair
Low molecular weight phosphotyrosine protein phosphatase


(Bos taurus)
BDBM50371128
PNG
(CHEMBL390401)
Show SMILES OC(=O)c1ccc2NC(C3CC=CC3c2c1)c1ccccc1
Show InChI InChI=1S/C19H17NO2/c21-19(22)13-9-10-17-16(11-13)14-7-4-8-15(14)18(20-17)12-5-2-1-3-6-12/h1-7,9-11,14-15,18,20H,8H2,(H,21,22)
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Institute for Research in Biomedicine (IRB)

Curated by ChEMBL


Assay Description
Inhibition of bovine low molecular weight PTP expressed in Escherichia coli BL21(D3) cells


Eur J Med Chem 42: 1102-8 (2007)


Article DOI: 10.1016/j.ejmech.2007.01.017
BindingDB Entry DOI: 10.7270/Q27W6D1F
More data for this
Ligand-Target Pair
Low molecular weight phosphotyrosine protein phosphatase


(Bos taurus)
BDBM50371129
PNG
(CHEMBL244328)
Show SMILES OC(=O)c1ccc2[nH]c3CCCCc3c2c1
Show InChI InChI=1S/C13H13NO2/c15-13(16)8-5-6-12-10(7-8)9-3-1-2-4-11(9)14-12/h5-7,14H,1-4H2,(H,15,16)
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Institute for Research in Biomedicine (IRB)

Curated by ChEMBL


Assay Description
Inhibition of bovine low molecular weight PTP expressed in Escherichia coli BL21(D3) cells


Eur J Med Chem 42: 1102-8 (2007)


Article DOI: 10.1016/j.ejmech.2007.01.017
BindingDB Entry DOI: 10.7270/Q27W6D1F
More data for this
Ligand-Target Pair
Low molecular weight phosphotyrosine protein phosphatase


(Bos taurus)
BDBM50371116
PNG
(CHEMBL242148)
Show SMILES Cn1c2ccc(cc2oc1=O)S(=O)(=O)N1CCC(CC1)C(O)=O
Show InChI InChI=1S/C14H16N2O6S/c1-15-11-3-2-10(8-12(11)22-14(15)19)23(20,21)16-6-4-9(5-7-16)13(17)18/h2-3,8-9H,4-7H2,1H3,(H,17,18)
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Institute for Research in Biomedicine (IRB)

Curated by ChEMBL


Assay Description
Inhibition of bovine low molecular weight PTP expressed in Escherichia coli BL21(D3) cells


Eur J Med Chem 42: 1102-8 (2007)


Article DOI: 10.1016/j.ejmech.2007.01.017
BindingDB Entry DOI: 10.7270/Q27W6D1F
More data for this
Ligand-Target Pair
Low molecular weight phosphotyrosine protein phosphatase


(Bos taurus)
BDBM50371122
PNG
(CHEMBL242363)
Show SMILES OC(=O)CCC(=O)N1CCc2cc(ccc12)S(=O)(=O)NCc1cccs1
Show InChI InChI=1S/C17H18N2O5S2/c20-16(5-6-17(21)22)19-8-7-12-10-14(3-4-15(12)19)26(23,24)18-11-13-2-1-9-25-13/h1-4,9-10,18H,5-8,11H2,(H,21,22)
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>1.00E+6n/an/an/an/an/an/an/an/a



Institute for Research in Biomedicine (IRB)

Curated by ChEMBL


Assay Description
Inhibition of bovine low molecular weight PTP expressed in Escherichia coli BL21(D3) cells


Eur J Med Chem 42: 1102-8 (2007)


Article DOI: 10.1016/j.ejmech.2007.01.017
BindingDB Entry DOI: 10.7270/Q27W6D1F
More data for this
Ligand-Target Pair