Compile Data Set for Download or QSAR
maximum 50k data
Found 7 of ic50 for UniProtKB: P04792
TargetHeat shock protein beta-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50263167(3,4,5,6-Tetrahydro-2H-[1,2']bipyridinyl-4'-carboxy...)
Affinity DataIC50:  6nMAssay Description:Inhibition of HSP27 phosphorylation in IL1alpha-stimulated HLF cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein beta-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50263168(CHEMBL476351 | N-[4'-(Cyclopropylmethyl-carbamoyl)...)
Affinity DataIC50:  27nMAssay Description:Inhibition of HSP27 phosphorylation in IL1alpha-stimulated HLF cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein beta-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50263093(6-Methyl-biphenyl-3,4'-dicarboxylic acid 3-cyclopr...)
Affinity DataIC50:  53nMAssay Description:Inhibition of HSP27 phosphorylation in IL1alpha-stimulated HLF cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein beta-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM13533(1-[2-(4-methylphenyl)-5-tert-butyl-pyrazol-3-yl]-3...)
Affinity DataIC50:  58nMAssay Description:Inhibition of HSP27 phosphorylation in IL1alpha-stimulated HLF cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein beta-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50262865(CHEMBL477583 | Furan-3-carboxylic acid [4'-(cyclop...)
Affinity DataIC50:  88nMAssay Description:Inhibition of HSP27 phosphorylation in IL1alpha-stimulated HLF cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein beta-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM15458(4-[4-(4-fluorophenyl)-1-(piperidin-4-yl)-1H-imidaz...)
Affinity DataIC50:  160nMAssay Description:Inhibition of HSP27 phosphorylation in IL1alpha-stimulated HLF cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein beta-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50097558(CHEMBL1935538 | NSC-751382)
Affinity DataIC50:  200nMAssay Description:Inhibition of HSP27 (unknown origin) by insulin aggregation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed