Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Amiloride-sensitive cation channel 2, neuronal (Homo sapiens) | BDBM50096642![]() (CHEMBL3577296) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 6.20 | n/a | n/a | n/a | n/a |
TBA | Assay Description Orthosteric non-competitive inhibition of human ASIC1a endogenously expressed in HEK293 cells clamped at -100 mV gated ionic current assessed as EC50... | Citation and Details Article DOI: 10.1021/jm5017329 BindingDB Entry DOI: 10.7270/Q2FT8NTK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Amiloride-sensitive cation channel 2, neuronal (Homo sapiens) | BDBM50096642![]() (CHEMBL3577296) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 6.40 | n/a | n/a | n/a | n/a |
TBA | Assay Description Orthosteric non-competitive inhibition of human ASIC1a endogenously expressed in HEK293 cells clamped at -100 mV gated ionic current assessed as EC50... | Citation and Details Article DOI: 10.1021/jm5017329 BindingDB Entry DOI: 10.7270/Q2FT8NTK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Amiloride-sensitive cation channel 2, neuronal (Homo sapiens) | BDBM50096642![]() (CHEMBL3577296) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 6.5 | n/a | n/a | n/a | n/a |
TBA | Assay Description Orthosteric non-competitive inhibition of human ASIC1a endogenously expressed in HEK293 cells clamped at -100 mV gated ionic current assessed as EC50... | Citation and Details Article DOI: 10.1021/jm5017329 BindingDB Entry DOI: 10.7270/Q2FT8NTK | |||||||||||
More data for this Ligand-Target Pair |