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Compile Data Set for Download or QSAR

Found 496 hits of ic50 data for polymerid = 50006046,8873   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM?mit=repeat
Kd
nM
EC50/IC50
nM?mit=repeat
koff
s-1
kon
M-1s-1
pHTemp
°C
Fatty acid-binding protein 4 (FABP4)


(Homo sapiens (Human))
BDBM263053
PNG
(US9708340, 30)
Show SMILES OC(=O)[C@H]1CCN1C(=O)Nc1cc(Cl)c(F)cc1-c1ccccc1
Show InChI InChI=1S/C17H14ClFN2O3/c18-12-9-14(20-17(24)21-7-6-15(21)16(22)23)11(8-13(12)19)10-4-2-1-3-5-10/h1-5,8-9,15H,6-7H2,(H,20,24)(H,22,23)/t15-/m1/s1
PDB

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n/an/a 20n/an/an/an/a7.525



Hoffmann-La Roche Inc.

US Patent


Assay Description
Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...


US Patent US9708340 (2017)

More data for this
Ligand-Target Pair
Fatty acid-binding protein 4 (FABP4)


(Homo sapiens (Human))
BDBM263071
PNG
(US9708340, 64)
Show SMILES COc1cc(Cl)cc(NC(=O)N2CC[C@@H]2C(O)=O)c1-c1ccc(F)cc1
Show InChI InChI=1S/C18H16ClFN2O4/c1-26-15-9-11(19)8-13(16(15)10-2-4-12(20)5-3-10)21-18(25)22-7-6-14(22)17(23)24/h2-5,8-9,14H,6-7H2,1H3,(H,21,25)(H,23,24)/t14-/m1/s1
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n/an/a 20n/an/an/an/a7.525



Hoffmann-La Roche Inc.

US Patent


Assay Description
Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...


US Patent US9708340 (2017)

More data for this
Ligand-Target Pair
Fatty acid-binding protein 4 (FABP4)


(Homo sapiens (Human))
BDBM312319
PNG
(2-[3-(3-Isopropyl-[1,2,4]oxadiazol-5-yl)-4,5,6,7-t...)
Show SMILES CC(C)c1noc(n1)-c1c(NC(=O)C2=C(CCC2)C(O)=O)sc2CCCCc12
Show InChI InChI=1S/C20H23N3O4S/c1-10(2)16-21-18(27-23-16)15-13-6-3-4-9-14(13)28-19(15)22-17(24)11-7-5-8-12(11)20(25)26/h10H,3-9H2,1-2H3,(H,22,24)(H,25,26)
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n/an/a 20n/an/an/an/an/an/a



Hoffman-La Roche Inc.

US Patent


Assay Description
Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...


US Patent US9604977 (2017)

More data for this
Ligand-Target Pair
Fatty acid-binding protein 4 (FABP4)


(Homo sapiens (Human))
BDBM234694
PNG
(US9353102, 6.11)
Show SMILES OC(=O)C1=C(CCC1)C(=O)Nc1scc(c1-c1nc(no1)C1CC1)C(F)(F)F
Show InChI InChI=1S/C17H14F3N3O4S/c18-17(19,20)10-6-28-15(11(10)14-21-12(23-27-14)7-4-5-7)22-13(24)8-2-1-3-9(8)16(25)26/h6-7H,1-5H2,(H,22,24)(H,25,26)
PDB

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n/an/a 20.5n/an/an/an/a7.5n/a



Hoffmann-La Roche Inc.

US Patent


Assay Description
Stock DMSO solutions (1.8 mM) of compounds were serially diluted 3-fold for ten concentrations with 100% DMSO (50 μM to 0.003 μM final comp...


US Patent US9353102 (2016)


BindingDB Entry DOI: 10.7270/Q23F4NH4
More data for this
Ligand-Target Pair
Fatty acid-binding protein 4 (FABP4)


(Homo sapiens (Human))
BDBM234698
PNG
(US9353102, 8 | US9353102, 9)
Show SMILES Cc1sc(NC(=O)C2=C(COCC2)C(O)=O)c(c1C)-c1nc(no1)C1CC1
Show InChI InChI=1S/C18H19N3O5S/c1-8-9(2)27-17(13(8)16-19-14(21-26-16)10-3-4-10)20-15(22)11-5-6-25-7-12(11)18(23)24/h10H,3-7H2,1-2H3,(H,20,22)(H,23,24)
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n/an/a 21n/an/an/an/a7.5n/a



Hoffmann-La Roche Inc.

US Patent


Assay Description
Stock DMSO solutions (1.8 mM) of compounds were serially diluted 3-fold for ten concentrations with 100% DMSO (50 μM to 0.003 μM final comp...


US Patent US9353102 (2016)


BindingDB Entry DOI: 10.7270/Q23F4NH4
More data for this
Ligand-Target Pair
Fatty acid-binding protein 4 (FABP4)


(Homo sapiens (Human))
BDBM312492
PNG
(3-[3-(3-Cyclopropyl-[1,2,4]oxadiazol-5-yl)-5,5-dim...)
Show SMILES CC1(C)CCc2sc(NC(=O)C3=C(C4CCC3CC4)C(O)=O)c(-c3nc(no3)C3CC3)c2C1
Show InChI InChI=1S/C25H29N3O4S/c1-25(2)10-9-16-15(11-25)19(22-26-20(28-32-22)14-7-8-14)23(33-16)27-21(29)17-12-3-5-13(6-4-12)18(17)24(30)31/h12-14H,3-11H2,1-2H3,(H,27,29)(H,30,31)
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n/an/a 22n/an/an/an/an/an/a



Hoffman-La Roche Inc.

US Patent


Assay Description
Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...


US Patent US9604977 (2017)

More data for this
Ligand-Target Pair
Fatty acid-binding protein 4 (FABP4)


(Homo sapiens (Human))
BDBM234704
PNG
(US9353102, 4.10)
Show SMILES Cc1nsc(n1)-c1c(C)c(sc1NC(=O)C1=C(CCC1)C(O)=O)C1CC1
Show InChI InChI=1S/C18H19N3O3S2/c1-8-13(17-19-9(2)21-26-17)16(25-14(8)10-6-7-10)20-15(22)11-4-3-5-12(11)18(23)24/h10H,3-7H2,1-2H3,(H,20,22)(H,23,24)
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n/an/a 22n/an/an/an/a7.5n/a



Hoffmann-La Roche Inc.

US Patent


Assay Description
Stock DMSO solutions (1.8 mM) of compounds were serially diluted 3-fold for ten concentrations with 100% DMSO (50 μM to 0.003 μM final comp...


US Patent US9353102 (2016)


BindingDB Entry DOI: 10.7270/Q23F4NH4
More data for this
Ligand-Target Pair
Fatty acid-binding protein 4 (FABP4)


(Homo sapiens (Human))
BDBM312450
PNG
(2-[6,6-Difluoro-3-(3-methyl-[1,2,4]thiadiazol-5-yl...)
Show SMILES Cc1nsc(n1)-c1c(NC(=O)C2=C(CCC2)C(O)=O)sc2CC(F)(F)CCc12
Show InChI InChI=1S/C18H17F2N3O3S2/c1-8-21-16(28-23-8)13-11-5-6-18(19,20)7-12(11)27-15(13)22-14(24)9-3-2-4-10(9)17(25)26/h2-7H2,1H3,(H,22,24)(H,25,26)
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n/an/a 22n/an/an/an/an/an/a



Hoffman-La Roche Inc.

US Patent


Assay Description
Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...


US Patent US9604977 (2017)

More data for this
Ligand-Target Pair
Fatty acid-binding protein 4 (FABP4)


(Homo sapiens (Human))
BDBM234710
PNG
(US9353102, 4.16)
Show SMILES Cc1nsc(n1)-c1c(C)c(C)sc1NC(=O)C1=C(CCCC1)C(O)=O
Show InChI InChI=1S/C17H19N3O3S2/c1-8-9(2)24-15(13(8)16-18-10(3)20-25-16)19-14(21)11-6-4-5-7-12(11)17(22)23/h4-7H2,1-3H3,(H,19,21)(H,22,23)
PDB

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n/an/a 23n/an/an/an/a7.5n/a



Hoffmann-La Roche Inc.

US Patent


Assay Description
Stock DMSO solutions (1.8 mM) of compounds were serially diluted 3-fold for ten concentrations with 100% DMSO (50 μM to 0.003 μM final comp...


US Patent US9353102 (2016)


BindingDB Entry DOI: 10.7270/Q23F4NH4
More data for this
Ligand-Target Pair
Fatty acid-binding protein 4 (FABP4)


(Homo sapiens (Human))
BDBM312455
PNG
(2-[3-(3-Methyl-[1,2,4]thiadiazol-5-yl)-4,5,6,7-tet...)
Show SMILES Cc1nsc(n1)-c1c(NC(=O)C2=C(CCC2)C(O)=O)sc2CCCCc12
Show InChI InChI=1S/C18H19N3O3S2/c1-9-19-17(26-21-9)14-12-5-2-3-8-13(12)25-16(14)20-15(22)10-6-4-7-11(10)18(23)24/h2-8H2,1H3,(H,20,22)(H,23,24)
PDB

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n/an/a 23n/an/an/an/an/an/a



Hoffman-La Roche Inc.

US Patent


Assay Description
Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...


US Patent US9604977 (2017)

More data for this
Ligand-Target Pair
Fatty acid-binding protein 4 (FABP4)


(Homo sapiens (Human))
BDBM312456
PNG
(2-[3-(3-Methyl-[1,2,4]thiadiazol-5-yl)-4,5,6,7-tet...)
Show SMILES Cc1nsc(n1)-c1c(NC(=O)C2=C(CCCC2)C(O)=O)sc2CCCCc12
Show InChI InChI=1S/C19H21N3O3S2/c1-10-20-18(27-22-10)15-13-8-4-5-9-14(13)26-17(15)21-16(23)11-6-2-3-7-12(11)19(24)25/h2-9H2,1H3,(H,21,23)(H,24,25)
PDB

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n/an/a 24n/an/an/an/an/an/a



Hoffman-La Roche Inc.

US Patent


Assay Description
Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...


US Patent US9604977 (2017)

More data for this
Ligand-Target Pair
Fatty acid-binding protein 4 (FABP4)


(Homo sapiens (Human))
BDBM312420
PNG
(2-[3-(3-Cyclopropyl-[1,2,4]oxadiazol-5-yl)-6-ethyl...)
Show SMILES CCC1CCc2c(C1)sc(NC(=O)C1=C(CCC1)C(O)=O)c2-c1nc(no1)C1CC1
Show InChI InChI=1S/C22H25N3O4S/c1-2-11-6-9-15-16(10-11)30-21(17(15)20-23-18(25-29-20)12-7-8-12)24-19(26)13-4-3-5-14(13)22(27)28/h11-12H,2-10H2,1H3,(H,24,26)(H,27,28)
PDB

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n/an/a 24n/an/an/an/an/an/a



Hoffman-La Roche Inc.

US Patent


Assay Description
Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...


US Patent US9604977 (2017)

More data for this
Ligand-Target Pair
Fatty acid-binding protein 4 (FABP4)


(Homo sapiens (Human))
BDBM234708
PNG
(US9353102, 4.14)
Show SMILES Cc1nsc(n1)-c1c(C)c(C)sc1NC(=O)C1=C(CCC1)C(O)=O
Show InChI InChI=1S/C16H17N3O3S2/c1-7-8(2)23-14(12(7)15-17-9(3)19-24-15)18-13(20)10-5-4-6-11(10)16(21)22/h4-6H2,1-3H3,(H,18,20)(H,21,22)
PDB

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n/an/a 25n/an/an/an/a7.5n/a



Hoffmann-La Roche Inc.

US Patent


Assay Description
Stock DMSO solutions (1.8 mM) of compounds were serially diluted 3-fold for ten concentrations with 100% DMSO (50 μM to 0.003 μM final comp...


US Patent US9353102 (2016)


BindingDB Entry DOI: 10.7270/Q23F4NH4
More data for this
Ligand-Target Pair
Fatty acid-binding protein 4 (FABP4)


(Homo sapiens (Human))
BDBM312461
PNG
(2-[3-(3-Cyclopropyl-[1,2,4]thiadiazol-5-yl)-4,5,6,...)
Show SMILES OC(=O)C1=C(CCCC1)C(=O)Nc1sc2CCCCc2c1-c1nc(ns1)C1CC1
Show InChI InChI=1S/C21H23N3O3S2/c25-18(12-5-1-2-6-13(12)21(26)27)23-19-16(14-7-3-4-8-15(14)28-19)20-22-17(24-29-20)11-9-10-11/h11H,1-10H2,(H,23,25)(H,26,27)
PDB

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n/an/a 25n/an/an/an/an/an/a



Hoffman-La Roche Inc.

US Patent


Assay Description
Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...


US Patent US9604977 (2017)

More data for this
Ligand-Target Pair
Fatty acid-binding protein 4 (FABP4)


(Homo sapiens (Human))
BDBM312452
PNG
(2-[3-(3-Cyclopropyl-[1,2,4]thiadiazol-5-yl)-6,6-di...)
Show SMILES OC(=O)C1=C(CCC1)C(=O)Nc1sc2CC(F)(F)CCc2c1-c1nc(ns1)C1CC1
Show InChI InChI=1S/C20H19F2N3O3S2/c21-20(22)7-6-12-13(8-20)29-17(14(12)18-23-15(25-30-18)9-4-5-9)24-16(26)10-2-1-3-11(10)19(27)28/h9H,1-8H2,(H,24,26)(H,27,28)
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n/an/a 26n/an/an/an/an/an/a



Hoffman-La Roche Inc.

US Patent


Assay Description
Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...


US Patent US9604977 (2017)

More data for this
Ligand-Target Pair
Fatty acid-binding protein 4 (FABP4)


(Homo sapiens (Human))
BDBM312491
PNG
(2-[3-(3-Cyclopropyl-[1,2,4]oxadiazol-5-yl)-5,5-dim...)
Show SMILES CC1(C)CCc2sc(NC(=O)C3=C(CCCC3)C(O)=O)c(-c3nc(no3)C3CC3)c2C1
Show InChI InChI=1S/C23H27N3O4S/c1-23(2)10-9-16-15(11-23)17(20-24-18(26-30-20)12-7-8-12)21(31-16)25-19(27)13-5-3-4-6-14(13)22(28)29/h12H,3-11H2,1-2H3,(H,25,27)(H,28,29)
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n/an/a 26n/an/an/an/an/an/a



Hoffman-La Roche Inc.

US Patent


Assay Description
Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...


US Patent US9604977 (2017)

More data for this
Ligand-Target Pair
Fatty acid-binding protein 4 (FABP4)


(Homo sapiens (Human))
BDBM234703
PNG
(US9353102, 4.9)
Show SMILES Cc1sc(NC(=O)C2=C(C3CCC2CC3)C(O)=O)c(c1C)-c1nc(ns1)C1CC1
Show InChI InChI=1S/C21H23N3O3S2/c1-9-10(2)28-19(14(9)20-22-17(24-29-20)13-7-8-13)23-18(25)15-11-3-5-12(6-4-11)16(15)21(26)27/h11-13H,3-8H2,1-2H3,(H,23,25)(H,26,27)
PDB

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n/an/a 27n/an/an/an/a7.5n/a



Hoffmann-La Roche Inc.

US Patent


Assay Description
Stock DMSO solutions (1.8 mM) of compounds were serially diluted 3-fold for ten concentrations with 100% DMSO (50 μM to 0.003 μM final comp...


US Patent US9353102 (2016)


BindingDB Entry DOI: 10.7270/Q23F4NH4
More data for this
Ligand-Target Pair
Fatty acid-binding protein 4 (FABP4)


(Homo sapiens (Human))
BDBM234706
PNG
(US9353102, 4.12)
Show SMILES Cc1nsc(n1)-c1c(C)c(sc1NC(=O)C1=C(C2CCC1CC2)C(O)=O)C1CC1
Show InChI InChI=1S/C21H23N3O3S2/c1-9-14(20-22-10(2)24-29-20)19(28-17(9)13-7-8-13)23-18(25)15-11-3-5-12(6-4-11)16(15)21(26)27/h11-13H,3-8H2,1-2H3,(H,23,25)(H,26,27)
PDB

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n/an/a 29n/an/an/an/a7.5n/a



Hoffmann-La Roche Inc.

US Patent


Assay Description
Stock DMSO solutions (1.8 mM) of compounds were serially diluted 3-fold for ten concentrations with 100% DMSO (50 μM to 0.003 μM final comp...


US Patent US9353102 (2016)


BindingDB Entry DOI: 10.7270/Q23F4NH4
More data for this
Ligand-Target Pair
Fatty acid-binding protein 4 (FABP4)


(Homo sapiens (Human))
BDBM312341
PNG
(3-[3-(4-Trifluoromethyl-thiazol-2-yl)-4,5,6,7-tetr...)
Show SMILES OC(=O)C1=C(C2CCC1CC2)C(=O)Nc1sc2CCCCc2c1-c1nc(cs1)C(F)(F)F
Show InChI InChI=1S/C22H21F3N2O3S2/c23-22(24,25)14-9-31-19(26-14)17-12-3-1-2-4-13(12)32-20(17)27-18(28)15-10-5-7-11(8-6-10)16(15)21(29)30/h9-11H,1-8H2,(H,27,28)(H,29,30)
PDB

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n/an/a 30n/an/an/an/an/an/a



Hoffman-La Roche Inc.

US Patent


Assay Description
Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...


US Patent US9604977 (2017)

More data for this
Ligand-Target Pair
Fatty acid-binding protein 4 (FABP4)


(Homo sapiens (Human))
BDBM312316
PNG
(3-[3-(3-Cyclopropyl-[1,2,4]oxadiazol-5-yl)-4,7-dih...)
Show SMILES OC(=O)C1=C(C2CCC1CC2)C(=O)Nc1sc2COCCc2c1-c1nc(no1)C1CC1
Show InChI InChI=1S/C22H23N3O5S/c26-19(15-10-1-3-11(4-2-10)16(15)22(27)28)24-21-17(13-7-8-29-9-14(13)31-21)20-23-18(25-30-20)12-5-6-12/h10-12H,1-9H2,(H,24,26)(H,27,28)
PDB

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n/an/a 30n/an/an/an/an/an/a



Hoffman-La Roche Inc.

US Patent


Assay Description
Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...


US Patent US9604977 (2017)

More data for this
Ligand-Target Pair
Fatty acid-binding protein 4 (FABP4)


(Homo sapiens (Human))
BDBM312372
PNG
(2-[5-(3-Cyclopropyl-[1,2,4]oxadiazol-5-yl)-3-thia-...)
Show SMILES OC(=O)C1=C(CCC1)C(=O)Nc1sc2C3CCC(C3)c2c1-c1nc(no1)C1CC1
Show InChI InChI=1S/C21H21N3O4S/c25-18(12-2-1-3-13(12)21(26)27)23-20-15(19-22-17(24-28-19)9-4-5-9)14-10-6-7-11(8-10)16(14)29-20/h9-11H,1-8H2,(H,23,25)(H,26,27)
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n/an/a 30n/an/an/an/an/an/a



Hoffman-La Roche Inc.

US Patent


Assay Description
Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...


US Patent US9604977 (2017)

More data for this
Ligand-Target Pair
Fatty acid-binding protein 4 (FABP4)


(Homo sapiens (Human))
BDBM312374
PNG
(2-[3-(3-Methyl-[1,2,4]oxadiazol-5-yl)-5,6,7,8-tetr...)
Show SMILES Cc1noc(n1)-c1c(NC(=O)C2=C(CCC2)C(O)=O)sc2CCCCCc12
Show InChI InChI=1S/C19H21N3O4S/c1-10-20-17(26-22-10)15-13-6-3-2-4-9-14(13)27-18(15)21-16(23)11-7-5-8-12(11)19(24)25/h2-9H2,1H3,(H,21,23)(H,24,25)
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n/an/a 30n/an/an/an/an/an/a



Hoffman-La Roche Inc.

US Patent


Assay Description
Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...


US Patent US9604977 (2017)

More data for this
Ligand-Target Pair
Fatty acid-binding protein 4 (FABP4)


(Homo sapiens (Human))
BDBM312398
PNG
(2-[3-(3-Cyclopropyl-[1,2,4]oxadiazol-5-yl)-6,6-dif...)
Show SMILES OC(=O)C1=C(CCC1)C(=O)Nc1sc2CC(F)(F)CCc2c1-c1nc(no1)C1CC1
Show InChI InChI=1S/C20H19F2N3O4S/c21-20(22)7-6-12-13(8-20)30-18(14(12)17-23-15(25-29-17)9-4-5-9)24-16(26)10-2-1-3-11(10)19(27)28/h9H,1-8H2,(H,24,26)(H,27,28)
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n/an/a 30n/an/an/an/an/an/a



Hoffman-La Roche Inc.

US Patent


Assay Description
Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...


US Patent US9604977 (2017)

More data for this
Ligand-Target Pair
Fatty acid-binding protein 4 (FABP4)


(Homo sapiens (Human))
BDBM312405
PNG
(2-[6,6-Difluoro-3-(4-methyl-thiazol-2-yl)-4,5,6,7-...)
Show SMILES Cc1csc(n1)-c1c(NC(=O)C2=C(CCCC2)C(O)=O)sc2CC(F)(F)CCc12
Show InChI InChI=1S/C20H20F2N2O3S2/c1-10-9-28-17(23-10)15-13-6-7-20(21,22)8-14(13)29-18(15)24-16(25)11-4-2-3-5-12(11)19(26)27/h9H,2-8H2,1H3,(H,24,25)(H,26,27)
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n/an/a 30n/an/an/an/an/an/a



Hoffman-La Roche Inc.

US Patent


Assay Description
Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...


US Patent US9604977 (2017)

More data for this
Ligand-Target Pair
Fatty acid-binding protein 4 (FABP4)


(Homo sapiens (Human))
BDBM234672
PNG
(US9353102, 3.1)
Show SMILES Cc1sc(NC(=O)C2=C(C3CCC2CC3)C(O)=O)c(-c2nc(no2)C(F)(F)F)c1C1CC1
Show InChI InChI=1S/C21H20F3N3O4S/c1-8-12(9-2-3-9)15(17-26-20(27-31-17)21(22,23)24)18(32-8)25-16(28)13-10-4-6-11(7-5-10)14(13)19(29)30/h9-11H,2-7H2,1H3,(H,25,28)(H,29,30)
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n/an/a 30n/an/an/an/a7.5n/a



Hoffmann-La Roche Inc.

US Patent


Assay Description
Stock DMSO solutions (1.8 mM) of compounds were serially diluted 3-fold for ten concentrations with 100% DMSO (50 μM to 0.003 μM final comp...


US Patent US9353102 (2016)


BindingDB Entry DOI: 10.7270/Q23F4NH4
More data for this
Ligand-Target Pair
Fatty acid-binding protein 4 (FABP4)


(Homo sapiens (Human))
BDBM263052
PNG
(US9708340, 29)
Show SMILES OC(=O)[C@H]1CCN1C(=O)Nc1cc(Cl)ccc1-c1ccc(F)cc1
Show InChI InChI=1S/C17H14ClFN2O3/c18-11-3-6-13(10-1-4-12(19)5-2-10)14(9-11)20-17(24)21-8-7-15(21)16(22)23/h1-6,9,15H,7-8H2,(H,20,24)(H,22,23)/t15-/m1/s1
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n/an/a 30n/an/an/an/a7.525



Hoffmann-La Roche Inc.

US Patent


Assay Description
Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...


US Patent US9708340 (2017)

More data for this
Ligand-Target Pair
Fatty acid-binding protein 4 (FABP4)


(Homo sapiens (Human))
BDBM263054
PNG
(US9708340, 31)
Show SMILES Cc1cc(c(NC(=O)N2CC[C@@H]2C(O)=O)cc1Cl)-c1ccccc1
Show InChI InChI=1S/C18H17ClN2O3/c1-11-9-13(12-5-3-2-4-6-12)15(10-14(11)19)20-18(24)21-8-7-16(21)17(22)23/h2-6,9-10,16H,7-8H2,1H3,(H,20,24)(H,22,23)/t16-/m1/s1
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n/an/a 30n/an/an/an/a7.525



Hoffmann-La Roche Inc.

US Patent


Assay Description
Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...


US Patent US9708340 (2017)

More data for this
Ligand-Target Pair
Fatty acid-binding protein 4 (FABP4)


(Homo sapiens (Human))
BDBM263056
PNG
(US9708340, 37)
Show SMILES OC(=O)[C@H]1CCN1C(=O)Nc1cc(Cl)ccc1-c1ccccc1F
Show InChI InChI=1S/C17H14ClFN2O3/c18-10-5-6-12(11-3-1-2-4-13(11)19)14(9-10)20-17(24)21-8-7-15(21)16(22)23/h1-6,9,15H,7-8H2,(H,20,24)(H,22,23)/t15-/m1/s1
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n/an/a 30n/an/an/an/a7.525



Hoffmann-La Roche Inc.

US Patent


Assay Description
Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...


US Patent US9708340 (2017)

More data for this
Ligand-Target Pair
Fatty acid-binding protein 4 (FABP4)


(Homo sapiens (Human))
BDBM263057
PNG
(US9708340, 38)
Show SMILES OC(=O)[C@H]1CCN1C(=O)Nc1cc(Cl)ccc1-c1cccc(F)c1
Show InChI InChI=1S/C17H14ClFN2O3/c18-11-4-5-13(10-2-1-3-12(19)8-10)14(9-11)20-17(24)21-7-6-15(21)16(22)23/h1-5,8-9,15H,6-7H2,(H,20,24)(H,22,23)/t15-/m1/s1
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n/an/a 30n/an/an/an/a7.525



Hoffmann-La Roche Inc.

US Patent


Assay Description
Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...


US Patent US9708340 (2017)

More data for this
Ligand-Target Pair
Fatty acid-binding protein 4 (FABP4)


(Homo sapiens (Human))
BDBM263070
PNG
(US9708340, 63)
Show SMILES OC(=O)[C@H]1CCN1C(=O)Nc1cc(Cl)ccc1-c1ccc(F)cc1F
Show InChI InChI=1S/C17H13ClF2N2O3/c18-9-1-3-12(11-4-2-10(19)8-13(11)20)14(7-9)21-17(25)22-6-5-15(22)16(23)24/h1-4,7-8,15H,5-6H2,(H,21,25)(H,23,24)/t15-/m1/s1
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n/an/a 30n/an/an/an/a7.525



Hoffmann-La Roche Inc.

US Patent


Assay Description
Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...


US Patent US9708340 (2017)

More data for this
Ligand-Target Pair
Fatty acid-binding protein 4 (FABP4)


(Homo sapiens (Human))
BDBM312242
PNG
(2-[3-(3-Methyl-[1,2,4]oxadiazol-5-yl)-4,5,6,7-tetr...)
Show SMILES Cc1noc(n1)-c1c(NC(=O)C2=C(CCCC2)C(O)=O)sc2CCCCc12
Show InChI InChI=1S/C19H21N3O4S/c1-10-20-17(26-22-10)15-13-8-4-5-9-14(13)27-18(15)21-16(23)11-6-2-3-7-12(11)19(24)25/h2-9H2,1H3,(H,21,23)(H,24,25)
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n/an/a 30n/an/an/an/an/an/a



Hoffman-La Roche Inc.

US Patent


Assay Description
Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...


US Patent US9604977 (2017)

More data for this
Ligand-Target Pair
Fatty acid-binding protein 4 (FABP4)


(Homo sapiens (Human))
BDBM312307
PNG
(2-[3-(3-Cyclopropyl-[1,2,4]oxadiazol-5-yl)-4,7-dih...)
Show SMILES OC(=O)C1=C(CCC1)C(=O)Nc1sc2COCCc2c1-c1nc(no1)C1CC1
Show InChI InChI=1S/C19H19N3O5S/c23-16(10-2-1-3-11(10)19(24)25)21-18-14(12-6-7-26-8-13(12)28-18)17-20-15(22-27-17)9-4-5-9/h9H,1-8H2,(H,21,23)(H,24,25)
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n/an/a 30n/an/an/an/an/an/a



Hoffman-La Roche Inc.

US Patent


Assay Description
Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...


US Patent US9604977 (2017)

More data for this
Ligand-Target Pair
Fatty acid-binding protein 4 (FABP4)


(Homo sapiens (Human))
BDBM312347
PNG
(3-[3-(3-Cyclopropyl-[1,2,4]oxadiazol-5-yl)-6-methy...)
Show SMILES CC1CCc2c(C1)sc(NC(=O)C1=C(C3CCC1CC3)C(O)=O)c2-c1nc(no1)C1CC1
Show InChI InChI=1S/C24H27N3O4S/c1-11-2-9-15-16(10-11)32-23(19(15)22-25-20(27-31-22)14-7-8-14)26-21(28)17-12-3-5-13(6-4-12)18(17)24(29)30/h11-14H,2-10H2,1H3,(H,26,28)(H,29,30)
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n/an/a 30n/an/an/an/an/an/a



Hoffman-La Roche Inc.

US Patent


Assay Description
Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...


US Patent US9604977 (2017)

More data for this
Ligand-Target Pair
Fatty acid-binding protein 4 (FABP4)


(Homo sapiens (Human))
BDBM234705
PNG
(US9353102, 4.11)
Show SMILES Cc1nsc(n1)-c1c(C)c(sc1NC(=O)C1=C(CCCC1)C(O)=O)C1CC1
Show InChI InChI=1S/C19H21N3O3S2/c1-9-14(18-20-10(2)22-27-18)17(26-15(9)11-7-8-11)21-16(23)12-5-3-4-6-13(12)19(24)25/h11H,3-8H2,1-2H3,(H,21,23)(H,24,25)
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n/an/a 31n/an/an/an/a7.5n/a



Hoffmann-La Roche Inc.

US Patent


Assay Description
Stock DMSO solutions (1.8 mM) of compounds were serially diluted 3-fold for ten concentrations with 100% DMSO (50 μM to 0.003 μM final comp...


US Patent US9353102 (2016)


BindingDB Entry DOI: 10.7270/Q23F4NH4
More data for this
Ligand-Target Pair
Fatty acid-binding protein 4 (FABP4)


(Homo sapiens (Human))
BDBM312480
PNG
(2-[3-(3-Cyclopropyl-[1,2,4]oxadiazol-5-yl)-4,7-dih...)
Show SMILES OC(=O)c1cccnc1C(=O)Nc1sc2COCCc2c1-c1nc(no1)C1CC1
Show InChI InChI=1S/C19H16N4O5S/c24-16(14-11(19(25)26)2-1-6-20-14)22-18-13(10-5-7-27-8-12(10)29-18)17-21-15(23-28-17)9-3-4-9/h1-2,6,9H,3-5,7-8H2,(H,22,24)(H,25,26)
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n/an/a 33n/an/an/an/an/an/a



Hoffman-La Roche Inc.

US Patent


Assay Description
Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...


US Patent US9604977 (2017)

More data for this
Ligand-Target Pair
Fatty acid-binding protein 4 (FABP4)


(Homo sapiens (Human))
BDBM312458
PNG
(3-[3-(3-Methyl-[1,2,4]thiadiazol-5-yl)-4,5,6,7-tet...)
Show SMILES Cc1nsc(n1)-c1c(NC(=O)C2=C(C3CCC2CC3)C(O)=O)sc2CCCCc12
Show InChI InChI=1S/C21H23N3O3S2/c1-10-22-20(29-24-10)17-13-4-2-3-5-14(13)28-19(17)23-18(25)15-11-6-8-12(9-7-11)16(15)21(26)27/h11-12H,2-9H2,1H3,(H,23,25)(H,26,27)
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n/an/a 33n/an/an/an/an/an/a



Hoffman-La Roche Inc.

US Patent


Assay Description
Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...


US Patent US9604977 (2017)

More data for this
Ligand-Target Pair
Fatty acid-binding protein 4 (FABP4)


(Homo sapiens (Human))
BDBM312511
PNG
((R)-1-[[3-[3-(trifluoromethyl)-1,2,4-oxadiazol-5-y...)
Show SMILES OC(=O)[C@H]1CCCN1C(=O)Nc1sc2CCCCc2c1-c1nc(no1)C(F)(F)F
Show InChI InChI=1S/C17H17F3N4O4S/c18-17(19,20)15-21-12(28-23-15)11-8-4-1-2-6-10(8)29-13(11)22-16(27)24-7-3-5-9(24)14(25)26/h9H,1-7H2,(H,22,27)(H,25,26)/t9-/m1/s1
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n/an/a 34n/an/an/an/an/an/a



Hoffman-La Roche Inc.

US Patent


Assay Description
Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...


US Patent US9604977 (2017)

More data for this
Ligand-Target Pair
Fatty acid-binding protein 4 (FABP4)


(Homo sapiens (Human))
BDBM312377
PNG
(2-[3-(3-Cyclopropyl-[1,2,4]oxadiazol-5-yl)-5,6,7,8...)
Show SMILES OC(=O)C1=C(CCC1)C(=O)Nc1sc2CCCCCc2c1-c1nc(no1)C1CC1
Show InChI InChI=1S/C21H23N3O4S/c25-18(12-6-4-7-13(12)21(26)27)23-20-16(14-5-2-1-3-8-15(14)29-20)19-22-17(24-28-19)11-9-10-11/h11H,1-10H2,(H,23,25)(H,26,27)
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n/an/a 40n/an/an/an/an/an/a



Hoffman-La Roche Inc.

US Patent


Assay Description
Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...


US Patent US9604977 (2017)

More data for this
Ligand-Target Pair
Fatty acid-binding protein 4 (FABP4)


(Homo sapiens (Human))
BDBM312376
PNG
(3-[3-(3-Methyl-[1,2,4]oxadiazol-5-yl)-5,6,7,8-tetr...)
Show SMILES Cc1noc(n1)-c1c(NC(=O)C2=C(C3CCC2CC3)C(O)=O)sc2CCCCCc12
Show InChI InChI=1S/C22H25N3O4S/c1-11-23-20(29-25-11)18-14-5-3-2-4-6-15(14)30-21(18)24-19(26)16-12-7-9-13(10-8-12)17(16)22(27)28/h12-13H,2-10H2,1H3,(H,24,26)(H,27,28)
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n/an/a 40n/an/an/an/an/an/a



Hoffman-La Roche Inc.

US Patent


Assay Description
Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...


US Patent US9604977 (2017)

More data for this
Ligand-Target Pair
Fatty acid-binding protein 4 (FABP4)


(Homo sapiens (Human))
BDBM312375
PNG
(2-[3-(3-Methyl-[1,2,4]oxadiazol-5-yl)-5,6,7,8-tetr...)
Show SMILES Cc1noc(n1)-c1c(NC(=O)C2=C(CCCC2)C(O)=O)sc2CCCCCc12
Show InChI InChI=1S/C20H23N3O4S/c1-11-21-18(27-23-11)16-14-9-3-2-4-10-15(14)28-19(16)22-17(24)12-7-5-6-8-13(12)20(25)26/h2-10H2,1H3,(H,22,24)(H,25,26)
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n/an/a 40n/an/an/an/an/an/a



Hoffman-La Roche Inc.

US Patent


Assay Description
Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...


US Patent US9604977 (2017)

More data for this
Ligand-Target Pair
Fatty acid-binding protein 4 (FABP4)


(Homo sapiens (Human))
BDBM312351
PNG
(3-[3-(4-Cyclopropyl-thiazol-2-yl)-4,7-dihydro-5H-t...)
Show SMILES OC(=O)C1=C(C2CCC1CC2)C(=O)Nc1sc2COCCc2c1-c1nc(cs1)C1CC1
Show InChI InChI=1S/C23H24N2O4S2/c26-20(17-12-3-5-13(6-4-12)18(17)23(27)28)25-22-19(14-7-8-29-9-16(14)31-22)21-24-15(10-30-21)11-1-2-11/h10-13H,1-9H2,(H,25,26)(H,27,28)
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n/an/a 40n/an/an/an/an/an/a



Hoffman-La Roche Inc.

US Patent


Assay Description
Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...


US Patent US9604977 (2017)

More data for this
Ligand-Target Pair
Fatty acid-binding protein 4 (FABP4)


(Homo sapiens (Human))
BDBM312402
PNG
(2-[6,6-Difluoro-3-(3-trifluoromethyl-[1,2,4]oxadia...)
Show SMILES OC(=O)C1=C(CCCC1)C(=O)Nc1sc2CC(F)(F)CCc2c1-c1nc(no1)C(F)(F)F
Show InChI InChI=1S/C19H16F5N3O4S/c20-18(21)6-5-10-11(7-18)32-15(12(10)14-26-17(27-31-14)19(22,23)24)25-13(28)8-3-1-2-4-9(8)16(29)30/h1-7H2,(H,25,28)(H,29,30)
PDB

UniProtKB/SwissProt

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UniChem
US Patent
n/an/a 40n/an/an/an/an/an/a



Hoffman-La Roche Inc.

US Patent


Assay Description
Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...


US Patent US9604977 (2017)

More data for this
Ligand-Target Pair
Fatty acid-binding protein 4 (FABP4)


(Homo sapiens (Human))
BDBM312486
PNG
(3-[6,6-Difluoro-3-(4-isopropyl-thiazol-2-yl)-4,5,6...)
Show SMILES CC(C)c1csc(n1)-c1c(NC(=O)C2=C(C3CCC2CC3)C(O)=O)sc2CC(F)(F)CCc12
Show InChI InChI=1S/C24H26F2N2O3S2/c1-11(2)15-10-32-21(27-15)19-14-7-8-24(25,26)9-16(14)33-22(19)28-20(29)17-12-3-5-13(6-4-12)18(17)23(30)31/h10-13H,3-9H2,1-2H3,(H,28,29)(H,30,31)
PDB

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n/an/a 40n/an/an/an/an/an/a



Hoffman-La Roche Inc.

US Patent


Assay Description
Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...


US Patent US9604977 (2017)

More data for this
Ligand-Target Pair
Fatty acid-binding protein 4 (FABP4)


(Homo sapiens (Human))
BDBM312362
PNG
((+)-2-[3-(3-Cyclopropyl-[1,2,4]oxadiazol-5-yl)-6-m...)
Show SMILES C[C@@H]1CCc2c(C1)sc(NC(=O)C1=C(CCCC1)C(O)=O)c2-c1nc(no1)C1CC1
Show InChI InChI=1S/C22H25N3O4S/c1-11-6-9-15-16(10-11)30-21(17(15)20-23-18(25-29-20)12-7-8-12)24-19(26)13-4-2-3-5-14(13)22(27)28/h11-12H,2-10H2,1H3,(H,24,26)(H,27,28)/t11-/m1/s1
PDB

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n/an/a 40n/an/an/an/an/an/a



Hoffman-La Roche Inc.

US Patent


Assay Description
Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...


US Patent US9604977 (2017)

More data for this
Ligand-Target Pair
Fatty acid-binding protein 4 (FABP4)


(Homo sapiens (Human))
BDBM234680
PNG
(US9353102, 4.4)
Show SMILES Cc1sc(NC(=O)C2=C(C3CCC2CC3)C(O)=O)c(c1C)-c1nc(no1)C1CC1
Show InChI InChI=1S/C21H23N3O4S/c1-9-10(2)29-20(14(9)19-22-17(24-28-19)13-7-8-13)23-18(25)15-11-3-5-12(6-4-11)16(15)21(26)27/h11-13H,3-8H2,1-2H3,(H,23,25)(H,26,27)
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n/an/a 40n/an/an/an/a7.5n/a



Hoffmann-La Roche Inc.

US Patent


Assay Description
Stock DMSO solutions (1.8 mM) of compounds were serially diluted 3-fold for ten concentrations with 100% DMSO (50 μM to 0.003 μM final comp...


US Patent US9353102 (2016)


BindingDB Entry DOI: 10.7270/Q23F4NH4
More data for this
Ligand-Target Pair
Fatty acid-binding protein 4 (FABP4)


(Homo sapiens (Human))
BDBM234690
PNG
(US9353102, 6.7)
Show SMILES OC(=O)C1=C(CCC1)C(=O)Nc1sc(cc1-c1nc(no1)C1CC1)C1CC1
Show InChI InChI=1S/C19H19N3O4S/c23-16(11-2-1-3-12(11)19(24)25)21-18-13(8-14(27-18)9-4-5-9)17-20-15(22-26-17)10-6-7-10/h8-10H,1-7H2,(H,21,23)(H,24,25)
PDB

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US Patent
n/an/a 40.8n/an/an/an/a7.5n/a



Hoffmann-La Roche Inc.

US Patent


Assay Description
Stock DMSO solutions (1.8 mM) of compounds were serially diluted 3-fold for ten concentrations with 100% DMSO (50 μM to 0.003 μM final comp...


US Patent US9353102 (2016)


BindingDB Entry DOI: 10.7270/Q23F4NH4
More data for this
Ligand-Target Pair
Fatty acid-binding protein 4 (FABP4)


(Homo sapiens (Human))
BDBM312421
PNG
(2-[(S)-3-(3-Cyclopropyl-[1,2,4]oxadiazol-5-yl)-6-e...)
Show SMILES CC[C@H]1CCc2c(C1)sc(NC(=O)C1=C(CCC1)C(O)=O)c2-c1nc(no1)C1CC1
Show InChI InChI=1S/C22H25N3O4S/c1-2-11-6-9-15-16(10-11)30-21(17(15)20-23-18(25-29-20)12-7-8-12)24-19(26)13-4-3-5-14(13)22(27)28/h11-12H,2-10H2,1H3,(H,24,26)(H,27,28)/t11-/m0/s1
PDB

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n/an/a 42n/an/an/an/an/an/a



Hoffman-La Roche Inc.

US Patent


Assay Description
Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...


US Patent US9604977 (2017)

More data for this
Ligand-Target Pair
Fatty acid-binding protein 4 (FABP4)


(Homo sapiens (Human))
BDBM234700
PNG
(US9353102, 4.6)
Show SMILES Cc1nsc(n1)-c1c(C)c(C)sc1NC(=O)C1=C(C2CCC1CC2)C(O)=O
Show InChI InChI=1S/C19H21N3O3S2/c1-8-9(2)26-17(13(8)18-20-10(3)22-27-18)21-16(23)14-11-4-6-12(7-5-11)15(14)19(24)25/h11-12H,4-7H2,1-3H3,(H,21,23)(H,24,25)
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n/an/a 44n/an/an/an/a7.5n/a



Hoffmann-La Roche Inc.

US Patent


Assay Description
Stock DMSO solutions (1.8 mM) of compounds were serially diluted 3-fold for ten concentrations with 100% DMSO (50 μM to 0.003 μM final comp...


US Patent US9353102 (2016)


BindingDB Entry DOI: 10.7270/Q23F4NH4
More data for this
Ligand-Target Pair
Fatty acid-binding protein 4 (FABP4)


(Homo sapiens (Human))
BDBM312506
PNG
(4-[3-(3-Cyclopropyl-[1,2,4]oxadiazol-5-yl)-6,6-dif...)
Show SMILES OC(=O)C1=C(CCOC1)C(=O)Nc1sc2CC(F)(F)CCc2c1-c1nc(no1)C1CC1
Show InChI InChI=1S/C20H19F2N3O5S/c21-20(22)5-3-11-13(7-20)31-18(14(11)17-23-15(25-30-17)9-1-2-9)24-16(26)10-4-6-29-8-12(10)19(27)28/h9H,1-8H2,(H,24,26)(H,27,28)
PDB

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n/an/a 45n/an/an/an/an/an/a



Hoffman-La Roche Inc.

US Patent


Assay Description
Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...


US Patent US9604977 (2017)

More data for this
Ligand-Target Pair
Fatty acid-binding protein 4 (FABP4)


(Homo sapiens (Human))
BDBM312499
PNG
(5-[3-(3-Cyclopropyl-[1,2,4]oxadiazol-5-yl)-4,5,6,7...)
Show SMILES OC(=O)C1=C(COCC1)C(=O)Nc1sc2CCCCc2c1-c1nc(no1)C1CC1
Show InChI InChI=1S/C20H21N3O5S/c24-17(13-9-27-8-7-11(13)20(25)26)22-19-15(12-3-1-2-4-14(12)29-19)18-21-16(23-28-18)10-5-6-10/h10H,1-9H2,(H,22,24)(H,25,26)
PDB

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n/an/a 45n/an/an/an/an/an/a



Hoffman-La Roche Inc.

US Patent


Assay Description
Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...


US Patent US9604977 (2017)

More data for this
Ligand-Target Pair
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