Compile Data Set for Download or QSAR
maximum 50k data
Found 103 of ic50 data for polymerid = 50006187,7054
TargetPhosphodiesterase(Trypanosoma brucei)
Mercachem

Curated by ChEMBL
LigandPNGBDBM50148195(CHEMBL3765188)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of recombinant Trypanosoma brucei PDEB1 using [3H]-cAMP as substrate after 15 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma brucei)
Mercachem

Curated by ChEMBL
LigandPNGBDBM50427452(CHEMBL2326941)
Affinity DataIC50:  4nMAssay Description:Inhibition of recombinant Trypanosoma brucei PDEB1 using [3H]-cAMP as substrate after 15 mins by scintillation proximity assayMore data for this Ligand-Target Pair
TargetPhosphodiesterase(Trypanosoma brucei)
Mercachem

Curated by ChEMBL
LigandPNGBDBM50427452(CHEMBL2326941)
Affinity DataIC50:  4nMAssay Description:Inhibition of Trypanosoma brucei full length PDEB1 expressed in insect SF21 cells using cAMP as substrate by scintillation proximity assayMore data for this Ligand-Target Pair
TargetPhosphodiesterase(Trypanosoma brucei)
Mercachem

Curated by ChEMBL
LigandPNGBDBM50427452(CHEMBL2326941)
Affinity DataIC50:  4nMAssay Description:Inhibition of recombinant Trypanosoma brucei PDEB1 using [3H]-cAMP as substrate after 15 mins by scintillation proximity assayMore data for this Ligand-Target Pair
TargetPhosphodiesterase(Trypanosoma brucei)
Mercachem

Curated by ChEMBL
LigandPNGBDBM50441529(CHEMBL2436771)
Affinity DataIC50:  4nMAssay Description:Inhibition of Trypanosoma brucei PDEB1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma brucei)
Mercachem

Curated by ChEMBL
LigandPNGBDBM50397108(CHEMBL85005)
Affinity DataIC50:  4nMAssay Description:Inhibition of Trypanosoma brucei TbrPDEB1More data for this Ligand-Target Pair
TargetPhosphodiesterase(Trypanosoma brucei)
Mercachem

Curated by ChEMBL
LigandPNGBDBM50148237(CHEMBL3763233)
Affinity DataIC50:  10nMAssay Description:Inhibition of recombinant Trypanosoma brucei PDEB1 using [3H]-cAMP as substrate after 15 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma brucei)
Mercachem

Curated by ChEMBL
LigandPNGBDBM50148238(CHEMBL3765037)
Affinity DataIC50:  13nMAssay Description:Inhibition of recombinant Trypanosoma brucei PDEB1 using [3H]-cAMP as substrate after 15 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma brucei)
Mercachem

Curated by ChEMBL
LigandPNGBDBM50148239(CHEMBL3764370)
Affinity DataIC50:  16nMAssay Description:Inhibition of recombinant Trypanosoma brucei PDEB1 using [3H]-cAMP as substrate after 15 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma brucei)
Mercachem

Curated by ChEMBL
LigandPNGBDBM50397078(CHEMBL2171452)
Affinity DataIC50:  49nMAssay Description:Inhibition of Trypanosoma brucei recombinant TbrPDEB1 expressed in Sf21 insect cells assessed as reduction of [3H]-cAMP hydrolysis by scintillation p...More data for this Ligand-Target Pair
TargetPhosphodiesterase(Trypanosoma brucei)
Mercachem

Curated by ChEMBL
LigandPNGBDBM50397078(CHEMBL2171452)
Affinity DataIC50:  55nMAssay Description:Inhibition of Trypanosoma brucei His-tagged catalytic domains of TbrPDEB1 expressed in Escherichia coli BL21 assessed as conversion of cAMP to AMP af...More data for this Ligand-Target Pair
TargetPhosphodiesterase(Trypanosoma brucei)
Mercachem

Curated by ChEMBL
LigandPNGBDBM50148255(CHEMBL3765786)
Affinity DataIC50:  63nMAssay Description:Inhibition of recombinant Trypanosoma brucei PDEB1 using [3H]-cAMP as substrate after 15 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma brucei)
Mercachem

Curated by ChEMBL
LigandPNGBDBM50148247(CHEMBL3765010)
Affinity DataIC50:  63nMAssay Description:Inhibition of recombinant Trypanosoma brucei PDEB1 using [3H]-cAMP as substrate after 15 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma brucei)
Mercachem

Curated by ChEMBL
LigandPNGBDBM50148254(CHEMBL3765606)
Affinity DataIC50:  63nMAssay Description:Inhibition of recombinant Trypanosoma brucei PDEB1 using [3H]-cAMP as substrate after 15 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma brucei)
Mercachem

Curated by ChEMBL
LigandPNGBDBM50148249(CHEMBL3763352)
Affinity DataIC50:  79nMAssay Description:Inhibition of recombinant Trypanosoma brucei PDEB1 using [3H]-cAMP as substrate after 15 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma brucei)
Mercachem

Curated by ChEMBL
LigandPNGBDBM50148250(CHEMBL3765222)
Affinity DataIC50:  79nMAssay Description:Inhibition of recombinant Trypanosoma brucei PDEB1 using [3H]-cAMP as substrate after 15 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma brucei)
Mercachem

Curated by ChEMBL
LigandPNGBDBM50148248(CHEMBL3765581)
Affinity DataIC50:  100nMAssay Description:Inhibition of recombinant Trypanosoma brucei PDEB1 using [3H]-cAMP as substrate after 15 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma brucei)
Mercachem

Curated by ChEMBL
LigandPNGBDBM50148252(CHEMBL3764909)
Affinity DataIC50:  100nMAssay Description:Inhibition of recombinant Trypanosoma brucei PDEB1 using [3H]-cAMP as substrate after 15 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma brucei)
Mercachem

Curated by ChEMBL
LigandPNGBDBM50148251(CHEMBL3765225)
Affinity DataIC50:  126nMAssay Description:Inhibition of recombinant Trypanosoma brucei PDEB1 using [3H]-cAMP as substrate after 15 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Leishmania major)
Vu University Amsterdam

Curated by ChEMBL
LigandPNGBDBM50397078(CHEMBL2171452)
Affinity DataIC50:  130nMAssay Description:Inhibition of Leishmania major recombinant PDEB1 expressed in Sf21 insect cells assessed as reduction of [3H]-cAMP hydrolysis by scintillation proxim...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma brucei)
Mercachem

Curated by ChEMBL
LigandPNGBDBM50148253(CHEMBL3765733)
Affinity DataIC50:  158nMAssay Description:Inhibition of recombinant Trypanosoma brucei PDEB1 using [3H]-cAMP as substrate after 15 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma brucei)
Mercachem

Curated by ChEMBL
LigandPNGBDBM50397079(CHEMBL2171451)
Affinity DataIC50:  160nMAssay Description:Inhibition of Trypanosoma brucei recombinant TbrPDEB1 expressed in Sf21 insect cells assessed as reduction of [3H]-cAMP hydrolysis by scintillation p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma brucei)
Mercachem

Curated by ChEMBL
LigandPNGBDBM50397082(CHEMBL2171460)
Affinity DataIC50:  250nMAssay Description:Inhibition of Trypanosoma brucei recombinant TbrPDEB1 expressed in Sf21 insect cells assessed as reduction of [3H]-cAMP hydrolysis by scintillation p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma brucei)
Mercachem

Curated by ChEMBL
LigandPNGBDBM50441528(CHEMBL2436772)
Affinity DataIC50:  278nMAssay Description:Inhibition of Trypanosoma brucei PDEB1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma brucei)
Mercachem

Curated by ChEMBL
LigandPNGBDBM50148194(CHEMBL3763456)
Affinity DataIC50:  316nMAssay Description:Inhibition of recombinant Trypanosoma brucei PDEB1 using [3H]-cAMP as substrate after 15 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma brucei)
Mercachem

Curated by ChEMBL
LigandPNGBDBM50148240(CHEMBL3763271)
Affinity DataIC50:  316nMAssay Description:Inhibition of recombinant Trypanosoma brucei PDEB1 using [3H]-cAMP as substrate after 15 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma brucei)
Mercachem

Curated by ChEMBL
LigandPNGBDBM50397086(CHEMBL2171456)
Affinity DataIC50:  400nMAssay Description:Inhibition of Trypanosoma brucei recombinant TbrPDEB1 expressed in Sf21 insect cells assessed as reduction of [3H]-cAMP hydrolysis by scintillation p...More data for this Ligand-Target Pair
TargetPhosphodiesterase(Trypanosoma brucei)
Mercachem

Curated by ChEMBL
LigandPNGBDBM50397106(CHEMBL2171660)
Affinity DataIC50:  410nMAssay Description:Inhibition of Trypanosoma brucei recombinant TbrPDEB1 expressed in Sf21 insect cells assessed as reduction of [3H]-cAMP hydrolysis by scintillation p...More data for this Ligand-Target Pair
TargetPhosphodiesterase(Trypanosoma brucei)
Mercachem

Curated by ChEMBL
LigandPNGBDBM50397081(CHEMBL2171461)
Affinity DataIC50:  500nMAssay Description:Inhibition of Trypanosoma brucei recombinant TbrPDEB1 expressed in Sf21 insect cells assessed as reduction of [3H]-cAMP hydrolysis by scintillation p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma brucei)
Mercachem

Curated by ChEMBL
LigandPNGBDBM50397102(CHEMBL2171664)
Affinity DataIC50:  500nMAssay Description:Inhibition of Trypanosoma brucei recombinant TbrPDEB1 expressed in Sf21 insect cells assessed as reduction of [3H]-cAMP hydrolysis by scintillation p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma brucei)
Mercachem

Curated by ChEMBL
LigandPNGBDBM50397080(CHEMBL2171462)
Affinity DataIC50:  630nMAssay Description:Inhibition of Trypanosoma brucei recombinant TbrPDEB1 expressed in Sf21 insect cells assessed as reduction of [3H]-cAMP hydrolysis by scintillation p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma brucei)
Mercachem

Curated by ChEMBL
LigandPNGBDBM50397083(CHEMBL2171459)
Affinity DataIC50:  630nMAssay Description:Inhibition of Trypanosoma brucei recombinant TbrPDEB1 expressed in Sf21 insect cells assessed as reduction of [3H]-cAMP hydrolysis by scintillation p...More data for this Ligand-Target Pair
TargetPhosphodiesterase(Trypanosoma brucei)
Mercachem

Curated by ChEMBL
LigandPNGBDBM50397084(CHEMBL2171458)
Affinity DataIC50:  790nMAssay Description:Inhibition of Trypanosoma brucei recombinant TbrPDEB1 expressed in Sf21 insect cells assessed as reduction of [3H]-cAMP hydrolysis by scintillation p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma brucei)
Mercachem

Curated by ChEMBL
LigandPNGBDBM50397090(CHEMBL2171658)
Affinity DataIC50:  790nMAssay Description:Inhibition of Trypanosoma brucei recombinant TbrPDEB1 expressed in Sf21 insect cells assessed as reduction of [3H]-cAMP hydrolysis by scintillation p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma brucei)
Mercachem

Curated by ChEMBL
LigandPNGBDBM50397091(CHEMBL2171657)
Affinity DataIC50:  830nMAssay Description:Inhibition of Trypanosoma brucei recombinant TbrPDEB1 expressed in Sf21 insect cells assessed as reduction of [3H]-cAMP hydrolysis by scintillation p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma brucei)
Mercachem

Curated by ChEMBL
LigandPNGBDBM50058062(CHEMBL3323128)
Affinity DataIC50:  950nMAssay Description:Inhibition of Trypanosoma brucei recombinant PDEB1 pre-incubated for 5 mins prior to substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma brucei)
Mercachem

Curated by ChEMBL
LigandPNGBDBM50397085(CHEMBL2171457)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of Trypanosoma brucei recombinant TbrPDEB1 expressed in Sf21 insect cells assessed as reduction of [3H]-cAMP hydrolysis by scintillation p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma brucei)
Mercachem

Curated by ChEMBL
LigandPNGBDBM50397103(CHEMBL2171663)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of Trypanosoma brucei recombinant TbrPDEB1 expressed in Sf21 insect cells assessed as reduction of [3H]-cAMP hydrolysis by scintillation p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma brucei)
Mercachem

Curated by ChEMBL
LigandPNGBDBM50148244(CHEMBL3763547)
Affinity DataIC50:  1.59E+3nMAssay Description:Inhibition of recombinant Trypanosoma brucei PDEB1 using [3H]-cAMP as substrate after 15 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma brucei)
Mercachem

Curated by ChEMBL
LigandPNGBDBM50148246(CHEMBL3764415)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of recombinant Trypanosoma brucei PDEB1 using [3H]-cAMP as substrate after 15 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma brucei)
Mercachem

Curated by ChEMBL
LigandPNGBDBM50397092(CHEMBL2171656)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of Trypanosoma brucei recombinant TbrPDEB1 expressed in Sf21 insect cells assessed as reduction of [3H]-cAMP hydrolysis by scintillation p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma brucei)
Mercachem

Curated by ChEMBL
LigandPNGBDBM50397097(CHEMBL2171651)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of Trypanosoma brucei recombinant TbrPDEB1 expressed in Sf21 insect cells assessed as reduction of [3H]-cAMP hydrolysis by scintillation p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma brucei)
Mercachem

Curated by ChEMBL
LigandPNGBDBM50397093(CHEMBL2171655)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of Trypanosoma brucei recombinant TbrPDEB1 expressed in Sf21 insect cells assessed as reduction of [3H]-cAMP hydrolysis by scintillation p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma brucei)
Mercachem

Curated by ChEMBL
LigandPNGBDBM50397094(CHEMBL2171654)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of Trypanosoma brucei recombinant TbrPDEB1 expressed in Sf21 insect cells assessed as reduction of [3H]-cAMP hydrolysis by scintillation p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma brucei)
Mercachem

Curated by ChEMBL
LigandPNGBDBM50397089(CHEMBL2171453)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of Trypanosoma brucei recombinant TbrPDEB1 expressed in Sf21 insect cells assessed as reduction of [3H]-cAMP hydrolysis by scintillation p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma brucei)
Mercachem

Curated by ChEMBL
LigandPNGBDBM153391(3-(3-carbamoyl-4-(3-methoxyphenylamino)-8-methylqu...)
Affinity DataIC50:  2.90E+3nMpH: 7.4Assay Description:In short, recombinant TbrPDEB1 and TbrPDEB2 were assayed in 10 mM Tris pH 7.4, bovine serum albumin (0.2 mg/mL), 10 mM MgCl2, 25然 cAMP (Enzo Lifesci...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma brucei)
Mercachem

Curated by ChEMBL
LigandPNGBDBM153402(4-((3-Methoxyphenyl)amino)-8-methyl-6-(1-methyl-1H...)
Affinity DataIC50:  3.10E+3nMpH: 7.4Assay Description:In short, recombinant TbrPDEB1 and TbrPDEB2 were assayed in 10 mM Tris pH 7.4, bovine serum albumin (0.2 mg/mL), 10 mM MgCl2, 25然 cAMP (Enzo Lifesci...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma brucei)
Mercachem

Curated by ChEMBL
LigandPNGBDBM153408(8-Methyl-6-(1-methyl-1H-indazol-6-yl)-4-(m-tolylam...)
Affinity DataIC50:  3.50E+3nMpH: 7.4Assay Description:In short, recombinant TbrPDEB1 and TbrPDEB2 were assayed in 10 mM Tris pH 7.4, bovine serum albumin (0.2 mg/mL), 10 mM MgCl2, 25然 cAMP (Enzo Lifesci...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma brucei)
Mercachem

Curated by ChEMBL
LigandPNGBDBM153390(Methyl 3-(3-carbamoyl-4-(3-methoxyphenylamino)-8-m...)
Affinity DataIC50:  3.50E+3nMpH: 7.4Assay Description:In short, recombinant TbrPDEB1 and TbrPDEB2 were assayed in 10 mM Tris pH 7.4, bovine serum albumin (0.2 mg/mL), 10 mM MgCl2, 25然 cAMP (Enzo Lifesci...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma brucei)
Mercachem

Curated by ChEMBL
LigandPNGBDBM153407(4-(3-Ethylphenylamino)-8-methyl-6-(1-methyl-1H-ind...)
Affinity DataIC50:  3.50E+3nMpH: 7.4Assay Description:In short, recombinant TbrPDEB1 and TbrPDEB2 were assayed in 10 mM Tris pH 7.4, bovine serum albumin (0.2 mg/mL), 10 mM MgCl2, 25然 cAMP (Enzo Lifesci...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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