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Found 14 of ic50 for UniProtKB: P04799
TargetCytochrome P450 1A2(Rattus norvegicus)
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50588805(CHEMBL5170790)
Affinity DataIC50:  1.31E+3nMAssay Description:Inhibition of CYP1A2 in rat liver Microsome using phenacetin as substrate in presence of NADPH by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCytochrome P450 1A2(Rattus norvegicus)
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM31772(1-[2-(2,4-dichlorobenzyl)oxy-2-(2,4-dichlorophenyl...)
Affinity DataIC50:  4.55E+3nMAssay Description:Inhibition of CYP1A2 in rat liver Microsome using phenacetin as substrate in presence of NADPH by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCytochrome P450 1A2(Rattus norvegicus)
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50588800(CHEMBL5190388)
Affinity DataIC50:  6.99E+3nMAssay Description:Inhibition of CYP1A2 in rat liver Microsome using phenacetin as substrate in presence of NADPH by LC-MS/MS analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCytochrome P450 1A2(Rattus norvegicus)
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM518570(US11124523, Example (+)-8)
Affinity DataIC50: >5.00E+4nMAssay Description:To test the inhibitory effects of the compounds of the present disclosure on different isoforms of human cytochrome P450 isoenzymesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCytochrome P450 1A2(Rattus norvegicus)
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM518571(US11124523, Example (+)-9)
Affinity DataIC50: >5.00E+4nMAssay Description:To test the inhibitory effects of the compounds of the present disclosure on different isoforms of human cytochrome P450 isoenzymesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCytochrome P450 1A2(Rattus norvegicus)
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM518580(US11124523, Example (+)-18)
Affinity DataIC50: >5.00E+4nMAssay Description:To test the inhibitory effects of the compounds of the present disclosure on different isoforms of human cytochrome P450 isoenzymesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCytochrome P450 1A2(Rattus norvegicus)
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM518586(US11124523, Example (+)-22)
Affinity DataIC50: >5.00E+4nMAssay Description:To test the inhibitory effects of the compounds of the present disclosure on different isoforms of human cytochrome P450 isoenzymesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCytochrome P450 1A2(Rattus norvegicus)
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM518587(US11124523, Example (+)-23)
Affinity DataIC50: >5.00E+4nMAssay Description:To test the inhibitory effects of the compounds of the present disclosure on different isoforms of human cytochrome P450 isoenzymesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCytochrome P450 1A2(Rattus norvegicus)
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM518593(US11124523, Example (+)-28b)
Affinity DataIC50: >5.00E+4nMAssay Description:To test the inhibitory effects of the compounds of the present disclosure on different isoforms of human cytochrome P450 isoenzymesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCytochrome P450 1A2(Rattus norvegicus)
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM518563(US11124523, Example (+)-2)
Affinity DataIC50: >5.00E+4nMAssay Description:To test the inhibitory effects of the compounds of the present disclosure on different isoforms of human cytochrome P450 isoenzymesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCytochrome P450 1A2(Rattus norvegicus)
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM518560(US11124523, Example (+)-1b)
Affinity DataIC50: >5.00E+4nMAssay Description:To test the inhibitory effects of the compounds of the present disclosure on different isoforms of human cytochrome P450 isoenzymesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCytochrome P450 1A2(Rattus norvegicus)
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50493818(Oliceridine | TRV-130 | US11124523, Comparative Co...)
Affinity DataIC50: >5.00E+4nMAssay Description:To test the inhibitory effects of the compounds of the present disclosure on different isoforms of human cytochrome P450 isoenzymesMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 1A2(Rattus norvegicus)
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM518578(US11124523, Example (+)-16)
Affinity DataIC50: >5.00E+4nMAssay Description:To test the inhibitory effects of the compounds of the present disclosure on different isoforms of human cytochrome P450 isoenzymesMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 1A2(Rattus norvegicus)
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50426305(ARTEMOTIL)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of CYP1A2 in rat liver microsome using phenacetin as substrate by HPLC-PDA analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed