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Compile Data Set for Download or QSAR

Found 47 hits of ic50 data for polymerid = 50007168   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Chromobox protein homolog 5


(Homo sapiens)
BDBM50194255
PNG
(CHEMBL3935965)
Show SMILES CCN(CC)CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccccc1)C(=O)N[C@@H](CO)C(=O)OC
Show InChI InChI=1S/C39H58N6O8/c1-7-45(8-2)22-16-15-21-30(36(49)44-33(25-46)39(52)53-6)41-38(51)31(23-26(3)4)42-34(47)27(5)40-37(50)32(24-28-17-11-9-12-18-28)43-35(48)29-19-13-10-14-20-29/h9-14,17-20,26-27,30-33,46H,7-8,15-16,21-25H2,1-6H3,(H,40,50)(H,41,51)(H,42,47)(H,43,48)(H,44,49)/t27-,30-,31-,32-,33-/m0/s1
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n/an/a 6.90E+3n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human N-terminal His-tagged CBX5 chromodomain (18 to 75 residues) expressed in Escherichia coli Rosetta BL21(DE3)p...


J Med Chem 59: 8913-8923 (2016)

More data for this
Ligand-Target Pair
Chromobox protein homolog 5


(Homo sapiens)
BDBM50194469
PNG
(CHEMBL3937936)
Show SMILES CCN(CC)CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccc(OC)cc1)C(=O)N[C@@H](CO)C(=O)OC
Show InChI InChI=1S/C40H60N6O9/c1-8-46(9-2)22-14-13-17-31(37(50)45-34(25-47)40(53)55-7)42-39(52)32(23-26(3)4)43-35(48)27(5)41-38(51)33(24-28-15-11-10-12-16-28)44-36(49)29-18-20-30(54-6)21-19-29/h10-12,15-16,18-21,26-27,31-34,47H,8-9,13-14,17,22-25H2,1-7H3,(H,41,51)(H,42,52)(H,43,48)(H,44,49)(H,45,50)/t27-,31-,32-,33-,34-/m0/s1
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n/an/a 1.20E+4n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human N-terminal His-tagged CBX5 chromodomain (18 to 75 residues) expressed in Escherichia coli Rosetta BL21(DE3)p...


J Med Chem 59: 8913-8923 (2016)

More data for this
Ligand-Target Pair
Chromobox protein homolog 5


(Homo sapiens)
BDBM50194474
PNG
(CHEMBL3953637)
Show SMILES CCN(CC)CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccc(CC)cc1)C(=O)N[C@@H](CO)C(=O)OC
Show InChI InChI=1S/C41H62N6O8/c1-8-29-19-21-31(22-20-29)37(50)45-34(25-30-16-12-11-13-17-30)39(52)42-28(6)36(49)44-33(24-27(4)5)40(53)43-32(18-14-15-23-47(9-2)10-3)38(51)46-35(26-48)41(54)55-7/h11-13,16-17,19-22,27-28,32-35,48H,8-10,14-15,18,23-26H2,1-7H3,(H,42,52)(H,43,53)(H,44,49)(H,45,50)(H,46,51)/t28-,32-,33-,34-,35-/m0/s1
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n/an/a 1.40E+4n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human N-terminal His-tagged CBX5 chromodomain (18 to 75 residues) expressed in Escherichia coli Rosetta BL21(DE3)p...


J Med Chem 59: 8913-8923 (2016)

More data for this
Ligand-Target Pair
Chromobox protein homolog 5


(Homo sapiens)
BDBM50194257
PNG
(CHEMBL3925993)
Show SMILES CCN(CC)CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccc(C)cc1)C(=O)N[C@@H](CO)C(=O)OC
Show InChI InChI=1S/C40H60N6O8/c1-8-46(9-2)22-14-13-17-31(37(50)45-34(25-47)40(53)54-7)42-39(52)32(23-26(3)4)43-35(48)28(6)41-38(51)33(24-29-15-11-10-12-16-29)44-36(49)30-20-18-27(5)19-21-30/h10-12,15-16,18-21,26,28,31-34,47H,8-9,13-14,17,22-25H2,1-7H3,(H,41,51)(H,42,52)(H,43,48)(H,44,49)(H,45,50)/t28-,31-,32-,33-,34-/m0/s1
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n/an/a 2.10E+4n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human N-terminal His-tagged CBX5 chromodomain (18 to 75 residues) expressed in Escherichia coli Rosetta BL21(DE3)p...


J Med Chem 59: 8913-8923 (2016)

More data for this
Ligand-Target Pair
Chromobox protein homolog 5


(Homo sapiens)
BDBM50194471
PNG
(CHEMBL3943850)
Show SMILES CCN(CC)CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccc(cc1)C(=O)OC)C(=O)N[C@@H](CO)C(=O)OC
Show InChI InChI=1S/C41H60N6O10/c1-8-47(9-2)22-14-13-17-31(37(51)46-34(25-48)41(55)57-7)43-39(53)32(23-26(3)4)44-35(49)27(5)42-38(52)33(24-28-15-11-10-12-16-28)45-36(50)29-18-20-30(21-19-29)40(54)56-6/h10-12,15-16,18-21,26-27,31-34,48H,8-9,13-14,17,22-25H2,1-7H3,(H,42,52)(H,43,53)(H,44,49)(H,45,50)(H,46,51)/t27-,31-,32-,33-,34-/m0/s1
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n/an/a 2.60E+4n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human N-terminal His-tagged CBX5 chromodomain (18 to 75 residues) expressed in Escherichia coli Rosetta BL21(DE3)p...


J Med Chem 59: 8913-8923 (2016)

More data for this
Ligand-Target Pair
Chromobox protein homolog 5


(Homo sapiens)
BDBM50194260
PNG
(CHEMBL3973366)
Show SMILES CCN(CC)CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccc(cc1)C(F)(F)F)C(=O)N[C@@H](CO)C(=O)OC
Show InChI InChI=1S/C40H57F3N6O8/c1-7-49(8-2)21-13-12-16-30(36(53)48-33(24-50)39(56)57-6)45-38(55)31(22-25(3)4)46-34(51)26(5)44-37(54)32(23-27-14-10-9-11-15-27)47-35(52)28-17-19-29(20-18-28)40(41,42)43/h9-11,14-15,17-20,25-26,30-33,50H,7-8,12-13,16,21-24H2,1-6H3,(H,44,54)(H,45,55)(H,46,51)(H,47,52)(H,48,53)/t26-,30-,31-,32-,33-/m0/s1
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n/an/a 3.30E+4n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human N-terminal His-tagged CBX5 chromodomain (18 to 75 residues) expressed in Escherichia coli Rosetta BL21(DE3)p...


J Med Chem 59: 8913-8923 (2016)

More data for this
Ligand-Target Pair
Chromobox protein homolog 5


(Homo sapiens)
BDBM50194258
PNG
(CHEMBL3934881)
Show SMILES CCN(CC)CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccc(cc1)C(C)C)C(=O)N[C@@H](CO)C(=O)OC
Show InChI InChI=1S/C42H64N6O8/c1-9-48(10-2)23-15-14-18-33(39(52)47-36(26-49)42(55)56-8)44-41(54)34(24-27(3)4)45-37(50)29(7)43-40(53)35(25-30-16-12-11-13-17-30)46-38(51)32-21-19-31(20-22-32)28(5)6/h11-13,16-17,19-22,27-29,33-36,49H,9-10,14-15,18,23-26H2,1-8H3,(H,43,53)(H,44,54)(H,45,50)(H,46,51)(H,47,52)/t29-,33-,34-,35-,36-/m0/s1
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n/an/a 3.80E+4n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human N-terminal His-tagged CBX5 chromodomain (18 to 75 residues) expressed in Escherichia coli Rosetta BL21(DE3)p...


J Med Chem 59: 8913-8923 (2016)

More data for this
Ligand-Target Pair
Chromobox protein homolog 5


(Homo sapiens)
BDBM50194477
PNG
(CHEMBL3916023)
Show SMILES CCN(CC)CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccc(CNC(=O)OC(C)(C)C)cc1)NC(=O)c1ccc(cc1)C(C)(C)C)C(=O)N[C@@H](CO)C(=O)OC
Show InChI InChI=1S/C49H77N7O10/c1-13-56(14-2)26-16-15-17-37(43(60)55-40(30-57)46(63)65-12)52-45(62)38(27-31(3)4)53-41(58)32(5)51-44(61)39(54-42(59)35-22-24-36(25-23-35)48(6,7)8)28-33-18-20-34(21-19-33)29-50-47(64)66-49(9,10)11/h18-25,31-32,37-40,57H,13-17,26-30H2,1-12H3,(H,50,64)(H,51,61)(H,52,62)(H,53,58)(H,54,59)(H,55,60)/t32-,37-,38-,39-,40-/m0/s1
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n/an/a 4.40E+4n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human N-terminal His-tagged CBX5 chromodomain (18 to 75 residues) expressed in Escherichia coli Rosetta BL21(DE3)p...


J Med Chem 59: 8913-8923 (2016)

More data for this
Ligand-Target Pair
Chromobox protein homolog 5


(Homo sapiens)
BDBM50194465
PNG
(CHEMBL3980951)
Show SMILES COC(=O)[C@H](CO)NC(=O)[C@H](CCCC[N+](C)(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccccc1
Show InChI InChI=1S/C38H56N6O8/c1-25(2)22-30(37(50)40-29(20-14-15-21-44(4,5)6)35(48)43-32(24-45)38(51)52-7)41-33(46)26(3)39-36(49)31(23-27-16-10-8-11-17-27)42-34(47)28-18-12-9-13-19-28/h8-13,16-19,25-26,29-32,45H,14-15,20-24H2,1-7H3,(H4-,39,40,41,42,43,46,47,48,49,50)/p+1/t26-,29-,30-,31-,32-/m0/s1
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n/an/a 4.90E+4n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human N-terminal His-tagged CBX5 chromodomain (18 to 75 residues) expressed in Escherichia coli Rosetta BL21(DE3)p...


J Med Chem 59: 8913-8923 (2016)

More data for this
Ligand-Target Pair
Chromobox protein homolog 5


(Homo sapiens)
BDBM50194458
PNG
(CHEMBL3987134)
Show SMILES CCN(CC)CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccc(CN)cc1)NC(=O)c1ccc(cc1)C(C)(C)C)C(=O)N[C@@H](CO)C(=O)OC
Show InChI InChI=1S/C44H69N7O8/c1-10-51(11-2)23-13-12-14-34(40(55)50-37(27-52)43(58)59-9)47-42(57)35(24-28(3)4)48-38(53)29(5)46-41(56)36(25-30-15-17-31(26-45)18-16-30)49-39(54)32-19-21-33(22-20-32)44(6,7)8/h15-22,28-29,34-37,52H,10-14,23-27,45H2,1-9H3,(H,46,56)(H,47,57)(H,48,53)(H,49,54)(H,50,55)/t29-,34-,35-,36-,37-/m0/s1
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n/an/a 5.30E+4n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human N-terminal His-tagged CBX5 chromodomain (18 to 75 residues) expressed in Escherichia coli Rosetta BL21(DE3)p...


J Med Chem 59: 8913-8923 (2016)

More data for this
Ligand-Target Pair
Chromobox protein homolog 5


(Homo sapiens)
BDBM50194472
PNG
(CHEMBL3965363)
Show SMILES COC(=O)[C@H](CO)NC(=O)[C@H](CCCC[N+](C)(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)c1ccccc1
Show InChI InChI=1S/C29H47N5O7/c1-19(2)17-23(32-25(36)20(3)30-26(37)21-13-9-8-10-14-21)28(39)31-22(15-11-12-16-34(4,5)6)27(38)33-24(18-35)29(40)41-7/h8-10,13-14,19-20,22-24,35H,11-12,15-18H2,1-7H3,(H3-,30,31,32,33,36,37,38,39)/p+1/t20-,22-,23-,24-/m0/s1
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n/an/a>6.00E+4n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human N-terminal His-tagged CBX5 chromodomain (18 to 75 residues) expressed in Escherichia coli Rosetta BL21(DE3)p...


J Med Chem 59: 8913-8923 (2016)

More data for this
Ligand-Target Pair
Chromobox protein homolog 5


(Homo sapiens)
BDBM50194460
PNG
(CHEMBL3942638)
Show SMILES CNC(=O)[C@H](CCCC[N+](C)(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)c1ccccc1
Show InChI InChI=1S/C26H43N5O4/c1-18(2)17-22(30-23(32)19(3)28-24(33)20-13-9-8-10-14-20)26(35)29-21(25(34)27-4)15-11-12-16-31(5,6)7/h8-10,13-14,18-19,21-22H,11-12,15-17H2,1-7H3,(H3-,27,28,29,30,32,33,34,35)/p+1/t19-,21-,22-/m0/s1
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n/an/a>6.00E+4n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human N-terminal His-tagged CBX5 chromodomain (18 to 75 residues) expressed in Escherichia coli Rosetta BL21(DE3)p...


J Med Chem 59: 8913-8923 (2016)

More data for this
Ligand-Target Pair
Chromobox protein homolog 5


(Homo sapiens)
BDBM50194463
PNG
(CHEMBL3974828)
Show SMILES CCN(CC)CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)c1ccccc1)C(=O)N[C@@H](CO)C(=O)OC
Show InChI InChI=1S/C41H61N7O9/c1-7-48(8-2)22-16-15-21-31(38(53)47-34(26-49)41(56)57-6)45-40(55)32(23-27(3)4)46-36(51)28(5)43-39(54)33(24-29-17-11-9-12-18-29)44-35(50)25-42-37(52)30-19-13-10-14-20-30/h9-14,17-20,27-28,31-34,49H,7-8,15-16,21-26H2,1-6H3,(H,42,52)(H,43,54)(H,44,50)(H,45,55)(H,46,51)(H,47,53)/t28-,31-,32-,33-,34-/m0/s1
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n/an/a>6.00E+4n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human N-terminal His-tagged CBX5 chromodomain (18 to 75 residues) expressed in Escherichia coli Rosetta BL21(DE3)p...


J Med Chem 59: 8913-8923 (2016)

More data for this
Ligand-Target Pair
Chromobox protein homolog 5


(Homo sapiens)
BDBM50194467
PNG
(CHEMBL3918626)
Show SMILES COC(=O)[C@H](CO)NC(=O)[C@H](CCCCN(C)C1CNC1)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)c1ccccc1
Show InChI InChI=1S/C41H60N8O9/c1-26(2)20-32(40(56)46-31(38(54)48-34(25-50)41(57)58-5)18-12-13-19-49(4)30-22-42-23-30)47-36(52)27(3)44-39(55)33(21-28-14-8-6-9-15-28)45-35(51)24-43-37(53)29-16-10-7-11-17-29/h6-11,14-17,26-27,30-34,42,50H,12-13,18-25H2,1-5H3,(H,43,53)(H,44,55)(H,45,51)(H,46,56)(H,47,52)(H,48,54)/t27-,31-,32-,33-,34-/m0/s1
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n/an/a>6.00E+4n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human N-terminal His-tagged CBX5 chromodomain (18 to 75 residues) expressed in Escherichia coli Rosetta BL21(DE3)p...


J Med Chem 59: 8913-8923 (2016)

More data for this
Ligand-Target Pair
Chromobox protein homolog 5


(Homo sapiens)
BDBM50194256
PNG
(CHEMBL3944916)
Show SMILES CCN(CC)CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)c1cccc(C)c1)C(=O)N[C@@H](CO)C(=O)OC
Show InChI InChI=1S/C40H60N6O8/c1-8-46(9-2)21-14-13-20-31(37(50)45-34(25-47)40(53)54-7)42-39(52)32(22-26(3)4)43-35(48)28(6)41-38(51)33(24-29-17-11-10-12-18-29)44-36(49)30-19-15-16-27(5)23-30/h10-12,15-19,23,26,28,31-34,47H,8-9,13-14,20-22,24-25H2,1-7H3,(H,41,51)(H,42,52)(H,43,48)(H,44,49)(H,45,50)/t28-,31-,32-,33-,34-/m0/s1
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n/an/a>6.00E+4n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human N-terminal His-tagged CBX5 chromodomain (18 to 75 residues) expressed in Escherichia coli Rosetta BL21(DE3)p...


J Med Chem 59: 8913-8923 (2016)

More data for this
Ligand-Target Pair
Chromobox protein homolog 5


(Homo sapiens)
BDBM50194466
PNG
(CHEMBL3958557)
Show SMILES COC(=O)[C@H](CO)NC(=O)[C@H](CCCC[N+](C)(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccc(cc1)C(C)(C)C
Show InChI InChI=1S/C42H64N6O8/c1-27(2)24-33(40(54)44-32(18-14-15-23-48(7,8)9)38(52)47-35(26-49)41(55)56-10)45-36(50)28(3)43-39(53)34(25-29-16-12-11-13-17-29)46-37(51)30-19-21-31(22-20-30)42(4,5)6/h11-13,16-17,19-22,27-28,32-35,49H,14-15,18,23-26H2,1-10H3,(H4-,43,44,45,46,47,50,51,52,53,54)/p+1/t28-,32-,33-,34-,35-/m0/s1
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n/an/a>6.00E+4n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human N-terminal His-tagged CBX5 chromodomain (18 to 75 residues) expressed in Escherichia coli Rosetta BL21(DE3)p...


J Med Chem 59: 8913-8923 (2016)

More data for this
Ligand-Target Pair
Chromobox protein homolog 5


(Homo sapiens)
BDBM50194475
PNG
(CHEMBL3889586)
Show SMILES CCN(CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccc(cc1)C(C)(C)C)C(=O)N[C@@H](CO)C(=O)OC)C(C)C
Show InChI InChI=1S/C44H68N6O8/c1-11-50(29(4)5)24-16-15-19-34(40(54)49-37(27-51)43(57)58-10)46-42(56)35(25-28(2)3)47-38(52)30(6)45-41(55)36(26-31-17-13-12-14-18-31)48-39(53)32-20-22-33(23-21-32)44(7,8)9/h12-14,17-18,20-23,28-30,34-37,51H,11,15-16,19,24-27H2,1-10H3,(H,45,55)(H,46,56)(H,47,52)(H,48,53)(H,49,54)/t30-,34-,35-,36-,37-/m0/s1
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n/an/a>6.00E+4n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human N-terminal His-tagged CBX5 chromodomain (18 to 75 residues) expressed in Escherichia coli Rosetta BL21(DE3)p...


J Med Chem 59: 8913-8923 (2016)

More data for this
Ligand-Target Pair
Chromobox protein homolog 5


(Homo sapiens)
BDBM50194449
PNG
(CHEMBL3905193)
Show SMILES CCN(CC)CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccc(cc1)C(C)(C)C)C(C)C)C(=O)N[C@@H](CO)C(=O)OC
Show InChI InChI=1S/C45H70N6O8/c1-11-51(12-2)25-17-16-20-34(40(54)49-37(28-52)44(58)59-10)46-41(55)35(26-29(3)4)48-43(57)38(30(5)6)50-42(56)36(27-31-18-14-13-15-19-31)47-39(53)32-21-23-33(24-22-32)45(7,8)9/h13-15,18-19,21-24,29-30,34-38,52H,11-12,16-17,20,25-28H2,1-10H3,(H,46,55)(H,47,53)(H,48,57)(H,49,54)(H,50,56)/t34-,35-,36-,37-,38-/m0/s1
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n/an/a>6.00E+4n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human N-terminal His-tagged CBX5 chromodomain (18 to 75 residues) expressed in Escherichia coli Rosetta BL21(DE3)p...


J Med Chem 59: 8913-8923 (2016)

More data for this
Ligand-Target Pair
Chromobox protein homolog 5


(Homo sapiens)
BDBM50194450
PNG
(CHEMBL3933207)
Show SMILES CCN(CC)CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccc(cc1)C(C)(C)C)C(=O)N[C@@H](CO)C(O)=O
Show InChI InChI=1S/C42H64N6O8/c1-9-48(10-2)23-15-14-18-32(38(52)47-35(26-49)41(55)56)44-40(54)33(24-27(3)4)45-36(50)28(5)43-39(53)34(25-29-16-12-11-13-17-29)46-37(51)30-19-21-31(22-20-30)42(6,7)8/h11-13,16-17,19-22,27-28,32-35,49H,9-10,14-15,18,23-26H2,1-8H3,(H,43,53)(H,44,54)(H,45,50)(H,46,51)(H,47,52)(H,55,56)/t28-,32-,33-,34-,35-/m0/s1
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n/an/a>6.00E+4n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human N-terminal His-tagged CBX5 chromodomain (18 to 75 residues) expressed in Escherichia coli Rosetta BL21(DE3)p...


J Med Chem 59: 8913-8923 (2016)

More data for this
Ligand-Target Pair
Chromobox protein homolog 5


(Homo sapiens)
BDBM50194476
PNG
(CHEMBL3942693)
Show SMILES CCN(CC)CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccc(cc1)C(C)(C)C)C(=O)N[C@@H](CO)C(=O)N(C)C
Show InChI InChI=1S/C44H69N7O7/c1-11-51(12-2)25-17-16-20-34(40(55)49-37(28-52)43(58)50(9)10)46-42(57)35(26-29(3)4)47-38(53)30(5)45-41(56)36(27-31-18-14-13-15-19-31)48-39(54)32-21-23-33(24-22-32)44(6,7)8/h13-15,18-19,21-24,29-30,34-37,52H,11-12,16-17,20,25-28H2,1-10H3,(H,45,56)(H,46,57)(H,47,53)(H,48,54)(H,49,55)/t30-,34-,35-,36-,37-/m0/s1
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n/an/a>6.00E+4n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human N-terminal His-tagged CBX5 chromodomain (18 to 75 residues) expressed in Escherichia coli Rosetta BL21(DE3)p...


J Med Chem 59: 8913-8923 (2016)

More data for this
Ligand-Target Pair
Chromobox protein homolog 5


(Homo sapiens)
BDBM50194386
PNG
(CHEMBL3963110)
Show SMILES COC(=O)[C@H](CO)NC(=O)[C@H](CCCC[N+](C)(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)N(C)C(=O)CNC(=O)c1ccccc1
Show InChI InChI=1S/C41H61N7O9/c1-27(2)23-32(39(54)44-31(21-15-16-22-48(5,6)7)38(53)46-33(26-49)41(56)57-8)45-36(51)28(3)43-40(55)34(24-29-17-11-9-12-18-29)47(4)35(50)25-42-37(52)30-19-13-10-14-20-30/h9-14,17-20,27-28,31-34,49H,15-16,21-26H2,1-8H3,(H4-,42,43,44,45,46,51,52,53,54,55)/p+1/t28-,31-,32-,33-,34-/m0/s1
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n/an/a>6.00E+4n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human N-terminal His-tagged CBX5 chromodomain (18 to 75 residues) expressed in Escherichia coli Rosetta BL21(DE3)p...


J Med Chem 59: 8913-8923 (2016)

More data for this
Ligand-Target Pair
Chromobox protein homolog 5


(Homo sapiens)
BDBM50194459
PNG
(CHEMBL3916833)
Show SMILES COC(=O)[C@H](CO)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)c1ccccc1
Show InChI InChI=1S/C37H53N7O9/c1-23(2)19-28(36(51)42-27(17-11-12-18-38)34(49)44-30(22-45)37(52)53-4)43-32(47)24(3)40-35(50)29(20-25-13-7-5-8-14-25)41-31(46)21-39-33(48)26-15-9-6-10-16-26/h5-10,13-16,23-24,27-30,45H,11-12,17-22,38H2,1-4H3,(H,39,48)(H,40,50)(H,41,46)(H,42,51)(H,43,47)(H,44,49)/t24-,27-,28-,29-,30-/m0/s1
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n/an/a>6.00E+4n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human N-terminal His-tagged CBX5 chromodomain (18 to 75 residues) expressed in Escherichia coli Rosetta BL21(DE3)p...


J Med Chem 59: 8913-8923 (2016)

More data for this
Ligand-Target Pair
Chromobox protein homolog 5


(Homo sapiens)
BDBM50194478
PNG
(CHEMBL3907836)
Show SMILES COC(=O)[C@H](CO)NC(=O)[C@H](CCCCNC1CCCC1)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)c1ccccc1
Show InChI InChI=1S/C42H61N7O9/c1-27(2)23-33(41(56)47-32(39(54)49-35(26-50)42(57)58-4)21-13-14-22-43-31-19-11-12-20-31)48-37(52)28(3)45-40(55)34(24-29-15-7-5-8-16-29)46-36(51)25-44-38(53)30-17-9-6-10-18-30/h5-10,15-18,27-28,31-35,43,50H,11-14,19-26H2,1-4H3,(H,44,53)(H,45,55)(H,46,51)(H,47,56)(H,48,52)(H,49,54)/t28-,32-,33-,34-,35-/m0/s1
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n/an/a>6.00E+4n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human N-terminal His-tagged CBX5 chromodomain (18 to 75 residues) expressed in Escherichia coli Rosetta BL21(DE3)p...


J Med Chem 59: 8913-8923 (2016)

More data for this
Ligand-Target Pair
Chromobox protein homolog 5


(Homo sapiens)
BDBM50194427
PNG
(CHEMBL3932467)
Show SMILES COC(=O)[C@H](CO)NC(=O)[C@H](CCCCNC1CC2CCC1C2)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)c1ccccc1
Show InChI InChI=1S/C44H63N7O9/c1-27(2)21-35(43(58)49-33(41(56)51-37(26-52)44(59)60-4)17-11-12-20-45-34-24-30-18-19-32(34)22-30)50-39(54)28(3)47-42(57)36(23-29-13-7-5-8-14-29)48-38(53)25-46-40(55)31-15-9-6-10-16-31/h5-10,13-16,27-28,30,32-37,45,52H,11-12,17-26H2,1-4H3,(H,46,55)(H,47,57)(H,48,53)(H,49,58)(H,50,54)(H,51,56)/t28-,30?,32?,33-,34?,35-,36-,37-/m0/s1
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n/an/a>6.00E+4n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human N-terminal His-tagged CBX5 chromodomain (18 to 75 residues) expressed in Escherichia coli Rosetta BL21(DE3)p...


J Med Chem 59: 8913-8923 (2016)

More data for this
Ligand-Target Pair
Chromobox protein homolog 5


(Homo sapiens)
BDBM50194251
PNG
(CHEMBL3955176)
Show SMILES COC(=O)[C@H](CO)NC(=O)[C@H](CCCCN(C1CCC1)C1CCC1)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)c1ccccc1
Show InChI InChI=1S/C45H65N7O9/c1-29(2)25-36(44(59)49-35(42(57)51-38(28-53)45(60)61-4)23-11-12-24-52(33-19-13-20-33)34-21-14-22-34)50-40(55)30(3)47-43(58)37(26-31-15-7-5-8-16-31)48-39(54)27-46-41(56)32-17-9-6-10-18-32/h5-10,15-18,29-30,33-38,53H,11-14,19-28H2,1-4H3,(H,46,56)(H,47,58)(H,48,54)(H,49,59)(H,50,55)(H,51,57)/t30-,35-,36-,37-,38-/m0/s1
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n/an/a>6.00E+4n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human N-terminal His-tagged CBX5 chromodomain (18 to 75 residues) expressed in Escherichia coli Rosetta BL21(DE3)p...


J Med Chem 59: 8913-8923 (2016)

More data for this
Ligand-Target Pair
Chromobox protein homolog 5


(Homo sapiens)
BDBM50194388
PNG
(CHEMBL3978346)
Show SMILES COC(=O)[C@H](CO)NC(=O)[C@H](CCCCNC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)c1ccccc1
Show InChI InChI=1S/C40H59N7O9/c1-25(2)21-31(39(54)45-30(19-13-14-20-41-26(3)4)37(52)47-33(24-48)40(55)56-6)46-35(50)27(5)43-38(53)32(22-28-15-9-7-10-16-28)44-34(49)23-42-36(51)29-17-11-8-12-18-29/h7-12,15-18,25-27,30-33,41,48H,13-14,19-24H2,1-6H3,(H,42,51)(H,43,53)(H,44,49)(H,45,54)(H,46,50)(H,47,52)/t27-,30-,31-,32-,33-/m0/s1
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n/an/a>6.00E+4n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human N-terminal His-tagged CBX5 chromodomain (18 to 75 residues) expressed in Escherichia coli Rosetta BL21(DE3)p...


J Med Chem 59: 8913-8923 (2016)

More data for this
Ligand-Target Pair
Chromobox protein homolog 5


(Homo sapiens)
BDBM50194261
PNG
(CHEMBL3970686)
Show SMILES CCN(CC)CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)Cc1ccc(cc1)C(C)(C)C)C(=O)N[C@@H](CO)C(=O)OC
Show InChI InChI=1S/C44H68N6O8/c1-10-50(11-2)24-16-15-19-34(40(54)49-37(28-51)43(57)58-9)47-42(56)35(25-29(3)4)48-39(53)30(5)45-41(55)36(26-31-17-13-12-14-18-31)46-38(52)27-32-20-22-33(23-21-32)44(6,7)8/h12-14,17-18,20-23,29-30,34-37,51H,10-11,15-16,19,24-28H2,1-9H3,(H,45,55)(H,46,52)(H,47,56)(H,48,53)(H,49,54)/t30-,34-,35-,36-,37-/m0/s1
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n/an/a>6.00E+4n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human N-terminal His-tagged CBX5 chromodomain (18 to 75 residues) expressed in Escherichia coli Rosetta BL21(DE3)p...


J Med Chem 59: 8913-8923 (2016)

More data for this
Ligand-Target Pair
Chromobox protein homolog 5


(Homo sapiens)
BDBM50194263
PNG
(CHEMBL3970021)
Show SMILES COC(=O)[C@H](CO)NC(=O)[C@H](CCCC[N+](C)(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)c1ccccc1
Show InChI InChI=1S/C40H59N7O9/c1-26(2)22-31(39(54)44-30(20-14-15-21-47(4,5)6)37(52)46-33(25-48)40(55)56-7)45-35(50)27(3)42-38(53)32(23-28-16-10-8-11-17-28)43-34(49)24-41-36(51)29-18-12-9-13-19-29/h8-13,16-19,26-27,30-33,48H,14-15,20-25H2,1-7H3,(H5-,41,42,43,44,45,46,49,50,51,52,53,54)/p+1/t27-,30-,31-,32-,33-/m0/s1
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n/an/a>6.00E+4n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human N-terminal His-tagged CBX5 chromodomain (18 to 75 residues) expressed in Escherichia coli Rosetta BL21(DE3)p...


J Med Chem 59: 8913-8923 (2016)

More data for this
Ligand-Target Pair
Chromobox protein homolog 5


(Homo sapiens)
BDBM50194356
PNG
(CHEMBL3951389)
Show SMILES COC(=O)[C@H](CO)NC(=O)[C@H](CCCC[N+](C)(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)N(C)C(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)c1ccccc1
Show InChI InChI=1S/C41H61N7O9/c1-27(2)23-32(39(54)44-31(21-15-16-22-48(5,6)7)38(53)46-34(26-49)41(56)57-8)45-36(51)28(3)47(4)40(55)33(24-29-17-11-9-12-18-29)43-35(50)25-42-37(52)30-19-13-10-14-20-30/h9-14,17-20,27-28,31-34,49H,15-16,21-26H2,1-8H3,(H4-,42,43,44,45,46,50,51,52,53,54)/p+1/t28-,31-,32-,33-,34-/m0/s1
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n/an/a>6.00E+4n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human N-terminal His-tagged CBX5 chromodomain (18 to 75 residues) expressed in Escherichia coli Rosetta BL21(DE3)p...


J Med Chem 59: 8913-8923 (2016)

More data for this
Ligand-Target Pair
Chromobox protein homolog 5


(Homo sapiens)
BDBM50194431
PNG
(CHEMBL3954152)
Show SMILES COC(=O)[C@H](CO)NC(=O)[C@H](CCCCN(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)c1ccccc1
Show InChI InChI=1S/C39H57N7O9/c1-25(2)21-30(38(53)43-29(19-13-14-20-46(4)5)36(51)45-32(24-47)39(54)55-6)44-34(49)26(3)41-37(52)31(22-27-15-9-7-10-16-27)42-33(48)23-40-35(50)28-17-11-8-12-18-28/h7-12,15-18,25-26,29-32,47H,13-14,19-24H2,1-6H3,(H,40,50)(H,41,52)(H,42,48)(H,43,53)(H,44,49)(H,45,51)/t26-,29-,30-,31-,32-/m0/s1
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n/an/a>6.00E+4n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human N-terminal His-tagged CBX5 chromodomain (18 to 75 residues) expressed in Escherichia coli Rosetta BL21(DE3)p...


J Med Chem 59: 8913-8923 (2016)

More data for this
Ligand-Target Pair
Chromobox protein homolog 5


(Homo sapiens)
BDBM50194262
PNG
(CHEMBL3949885)
Show SMILES CCN(CC)CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)OC
Show InChI InChI=1S/C42H61N7O8/c1-7-49(8-2)21-15-14-20-33(39(53)48-36(26-50)42(56)57-6)46-41(55)34(22-27(3)4)47-38(52)28(5)44-40(54)35(23-29-16-10-9-11-17-29)45-37(51)24-30-25-43-32-19-13-12-18-31(30)32/h9-13,16-19,25,27-28,33-36,43,50H,7-8,14-15,20-24,26H2,1-6H3,(H,44,54)(H,45,51)(H,46,55)(H,47,52)(H,48,53)/t28-,33-,34-,35-,36-/m0/s1
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n/an/a>6.00E+4n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human N-terminal His-tagged CBX5 chromodomain (18 to 75 residues) expressed in Escherichia coli Rosetta BL21(DE3)p...


J Med Chem 59: 8913-8923 (2016)

More data for this
Ligand-Target Pair
Chromobox protein homolog 5


(Homo sapiens)
BDBM50194387
PNG
(CHEMBL3986571)
Show SMILES COC(=O)[C@H](CO)NC(=O)[C@H](CCCC[N+](C)(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CN(C)C(=O)c1ccccc1
Show InChI InChI=1S/C41H61N7O9/c1-27(2)23-32(39(54)44-31(21-15-16-22-48(5,6)7)37(52)46-34(26-49)41(56)57-8)45-36(51)28(3)42-38(53)33(24-29-17-11-9-12-18-29)43-35(50)25-47(4)40(55)30-19-13-10-14-20-30/h9-14,17-20,27-28,31-34,49H,15-16,21-26H2,1-8H3,(H4-,42,43,44,45,46,50,51,52,53,54)/p+1/t28-,31-,32-,33-,34-/m0/s1
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n/an/a>6.00E+4n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human N-terminal His-tagged CBX5 chromodomain (18 to 75 residues) expressed in Escherichia coli Rosetta BL21(DE3)p...


J Med Chem 59: 8913-8923 (2016)

More data for this
Ligand-Target Pair
Chromobox protein homolog 5


(Homo sapiens)
BDBM50194473
PNG
(CHEMBL3916999)
Show SMILES CCN(CC)CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccccc1C)C(=O)N[C@@H](CO)C(=O)OC
Show InChI InChI=1S/C40H60N6O8/c1-8-46(9-2)22-16-15-21-31(37(50)45-34(25-47)40(53)54-7)42-39(52)32(23-26(3)4)43-35(48)28(6)41-38(51)33(24-29-18-11-10-12-19-29)44-36(49)30-20-14-13-17-27(30)5/h10-14,17-20,26,28,31-34,47H,8-9,15-16,21-25H2,1-7H3,(H,41,51)(H,42,52)(H,43,48)(H,44,49)(H,45,50)/t28-,31-,32-,33-,34-/m0/s1
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n/an/a>6.00E+4n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human N-terminal His-tagged CBX5 chromodomain (18 to 75 residues) expressed in Escherichia coli Rosetta BL21(DE3)p...


J Med Chem 59: 8913-8923 (2016)

More data for this
Ligand-Target Pair
Chromobox protein homolog 5


(Homo sapiens)
BDBM50194259
PNG
(CHEMBL3939958)
Show SMILES CCN(CC)CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccc(cc1)C(C)(C)C)C(=O)N[C@@H](CO)C(=O)OC
Show InChI InChI=1S/C43H66N6O8/c1-10-49(11-2)24-16-15-19-33(39(53)48-36(27-50)42(56)57-9)45-41(55)34(25-28(3)4)46-37(51)29(5)44-40(54)35(26-30-17-13-12-14-18-30)47-38(52)31-20-22-32(23-21-31)43(6,7)8/h12-14,17-18,20-23,28-29,33-36,50H,10-11,15-16,19,24-27H2,1-9H3,(H,44,54)(H,45,55)(H,46,51)(H,47,52)(H,48,53)/t29-,33-,34-,35-,36-/m0/s1
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n/an/a>6.00E+4n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human N-terminal His-tagged CBX5 chromodomain (18 to 75 residues) expressed in Escherichia coli Rosetta BL21(DE3)p...


J Med Chem 59: 8913-8923 (2016)

More data for this
Ligand-Target Pair
Chromobox protein homolog 5


(Homo sapiens)
BDBM50194462
PNG
(CHEMBL3898460)
Show SMILES CC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccc(cc1)C(C)(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN(CC)CC)C(=O)N[C@@H](CO)C(=O)OC
Show InChI InChI=1S/C44H68N6O8/c1-10-33(45-42(56)36(27-30-18-14-13-15-19-30)47-38(52)31-21-23-32(24-22-31)44(6,7)8)39(53)48-35(26-29(4)5)41(55)46-34(20-16-17-25-50(11-2)12-3)40(54)49-37(28-51)43(57)58-9/h13-15,18-19,21-24,29,33-37,51H,10-12,16-17,20,25-28H2,1-9H3,(H,45,56)(H,46,55)(H,47,52)(H,48,53)(H,49,54)/t33-,34-,35-,36-,37-/m0/s1
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n/an/a>6.00E+4n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human N-terminal His-tagged CBX5 chromodomain (18 to 75 residues) expressed in Escherichia coli Rosetta BL21(DE3)p...


J Med Chem 59: 8913-8923 (2016)

More data for this
Ligand-Target Pair
Chromobox protein homolog 5


(Homo sapiens)
BDBM50194447
PNG
(CHEMBL3978944)
Show SMILES CCN(CC)CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)Cc1ccc2ccccc2c1)C(=O)N[C@@H](CO)C(=O)OC
Show InChI InChI=1S/C44H62N6O8/c1-7-50(8-2)23-15-14-20-35(41(54)49-38(28-51)44(57)58-6)47-43(56)36(24-29(3)4)48-40(53)30(5)45-42(55)37(26-31-16-10-9-11-17-31)46-39(52)27-32-21-22-33-18-12-13-19-34(33)25-32/h9-13,16-19,21-22,25,29-30,35-38,51H,7-8,14-15,20,23-24,26-28H2,1-6H3,(H,45,55)(H,46,52)(H,47,56)(H,48,53)(H,49,54)/t30-,35-,36-,37-,38-/m0/s1
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n/an/a>6.00E+4n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human N-terminal His-tagged CBX5 chromodomain (18 to 75 residues) expressed in Escherichia coli Rosetta BL21(DE3)p...


J Med Chem 59: 8913-8923 (2016)

More data for this
Ligand-Target Pair
Chromobox protein homolog 5


(Homo sapiens)
BDBM50194457
PNG
(CHEMBL3969494)
Show SMILES CCN(CC)CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccc(cc1)C(C)(C)C)C(=O)NCCO
Show InChI InChI=1S/C41H64N6O6/c1-9-47(10-2)24-15-14-18-33(38(51)42-23-25-48)44-40(53)34(26-28(3)4)45-36(49)29(5)43-39(52)35(27-30-16-12-11-13-17-30)46-37(50)31-19-21-32(22-20-31)41(6,7)8/h11-13,16-17,19-22,28-29,33-35,48H,9-10,14-15,18,23-27H2,1-8H3,(H,42,51)(H,43,52)(H,44,53)(H,45,49)(H,46,50)/t29-,33-,34-,35-/m0/s1
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n/an/a>6.00E+4n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human N-terminal His-tagged CBX5 chromodomain (18 to 75 residues) expressed in Escherichia coli Rosetta BL21(DE3)p...


J Med Chem 59: 8913-8923 (2016)

More data for this
Ligand-Target Pair
Chromobox protein homolog 5


(Homo sapiens)
BDBM50194249
PNG
(CHEMBL3945426)
Show SMILES COC(=O)[C@H](CO)NC(=O)[C@H](CCCCN1CCCC1)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)c1ccccc1
Show InChI InChI=1S/C41H59N7O9/c1-27(2)23-32(40(55)45-31(19-11-12-20-48-21-13-14-22-48)38(53)47-34(26-49)41(56)57-4)46-36(51)28(3)43-39(54)33(24-29-15-7-5-8-16-29)44-35(50)25-42-37(52)30-17-9-6-10-18-30/h5-10,15-18,27-28,31-34,49H,11-14,19-26H2,1-4H3,(H,42,52)(H,43,54)(H,44,50)(H,45,55)(H,46,51)(H,47,53)/t28-,31-,32-,33-,34-/m0/s1
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n/an/a>6.00E+4n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human N-terminal His-tagged CBX5 chromodomain (18 to 75 residues) expressed in Escherichia coli Rosetta BL21(DE3)p...


J Med Chem 59: 8913-8923 (2016)

More data for this
Ligand-Target Pair
Chromobox protein homolog 5


(Homo sapiens)
BDBM50194470
PNG
(CHEMBL3982833)
Show SMILES COC(=O)[C@H](CO)NC(=O)[C@H](CCCCNC1C2CC3CC(C2)CC1C3)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)c1ccccc1
Show InChI InChI=1S/C47H67N7O9/c1-28(2)19-37(53-42(57)29(3)50-45(60)38(25-30-13-7-5-8-14-30)51-40(56)26-49-43(58)33-15-9-6-10-16-33)46(61)52-36(44(59)54-39(27-55)47(62)63-4)17-11-12-18-48-41-34-21-31-20-32(23-34)24-35(41)22-31/h5-10,13-16,28-29,31-32,34-39,41,48,55H,11-12,17-27H2,1-4H3,(H,49,58)(H,50,60)(H,51,56)(H,52,61)(H,53,57)(H,54,59)/t29-,31?,32?,34?,35?,36-,37-,38-,39-,41?/m0/s1
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n/an/a>6.00E+4n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human N-terminal His-tagged CBX5 chromodomain (18 to 75 residues) expressed in Escherichia coli Rosetta BL21(DE3)p...


J Med Chem 59: 8913-8923 (2016)

More data for this
Ligand-Target Pair
Chromobox protein homolog 5


(Homo sapiens)
BDBM50194468
PNG
(CHEMBL3966329)
Show SMILES COC(=O)[C@H](CO)NC(=O)[C@H](CCCCN1CCCCC1)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)c1ccccc1
Show InChI InChI=1S/C42H61N7O9/c1-28(2)24-33(41(56)46-32(39(54)48-35(27-50)42(57)58-4)20-12-15-23-49-21-13-7-14-22-49)47-37(52)29(3)44-40(55)34(25-30-16-8-5-9-17-30)45-36(51)26-43-38(53)31-18-10-6-11-19-31/h5-6,8-11,16-19,28-29,32-35,50H,7,12-15,20-27H2,1-4H3,(H,43,53)(H,44,55)(H,45,51)(H,46,56)(H,47,52)(H,48,54)/t29-,32-,33-,34-,35-/m0/s1
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n/an/a>6.00E+4n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human N-terminal His-tagged CBX5 chromodomain (18 to 75 residues) expressed in Escherichia coli Rosetta BL21(DE3)p...


J Med Chem 59: 8913-8923 (2016)

More data for this
Ligand-Target Pair
Chromobox protein homolog 5


(Homo sapiens)
BDBM50194426
PNG
(CHEMBL3906755)
Show SMILES COC(=O)[C@H](CO)NC(=O)[C@H](CCCCNC1CCCCC1)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)c1ccccc1
Show InChI InChI=1S/C43H63N7O9/c1-28(2)24-34(42(57)48-33(40(55)50-36(27-51)43(58)59-4)22-14-15-23-44-32-20-12-7-13-21-32)49-38(53)29(3)46-41(56)35(25-30-16-8-5-9-17-30)47-37(52)26-45-39(54)31-18-10-6-11-19-31/h5-6,8-11,16-19,28-29,32-36,44,51H,7,12-15,20-27H2,1-4H3,(H,45,54)(H,46,56)(H,47,52)(H,48,57)(H,49,53)(H,50,55)/t29-,33-,34-,35-,36-/m0/s1
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n/an/a>6.00E+4n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human N-terminal His-tagged CBX5 chromodomain (18 to 75 residues) expressed in Escherichia coli Rosetta BL21(DE3)p...


J Med Chem 59: 8913-8923 (2016)

More data for this
Ligand-Target Pair
Chromobox protein homolog 5


(Homo sapiens)
BDBM50194254
PNG
(CHEMBL3908012)
Show SMILES COC(=O)[C@H](CO)NC(=O)[C@H](CCCCNC1CN2CCC1CC2)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)c1ccccc1
Show InChI InChI=1S/C44H64N8O9/c1-28(2)23-34(43(59)49-33(41(57)51-37(27-53)44(60)61-4)17-11-12-20-45-36-26-52-21-18-31(36)19-22-52)50-39(55)29(3)47-42(58)35(24-30-13-7-5-8-14-30)48-38(54)25-46-40(56)32-15-9-6-10-16-32/h5-10,13-16,28-29,31,33-37,45,53H,11-12,17-27H2,1-4H3,(H,46,56)(H,47,58)(H,48,54)(H,49,59)(H,50,55)(H,51,57)/t29-,33-,34-,35-,36?,37-/m0/s1
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n/an/a>6.00E+4n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human N-terminal His-tagged CBX5 chromodomain (18 to 75 residues) expressed in Escherichia coli Rosetta BL21(DE3)p...


J Med Chem 59: 8913-8923 (2016)

More data for this
Ligand-Target Pair
Chromobox protein homolog 5


(Homo sapiens)
BDBM50194464
PNG
(CHEMBL3898819)
Show SMILES CC(C)C[C@H](NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccccc1)C(=O)NCCCCC[N+](C)(C)C
Show InChI InChI=1S/C33H49N5O4/c1-24(2)22-28(32(41)34-20-14-9-15-21-38(4,5)6)36-30(39)25(3)35-33(42)29(23-26-16-10-7-11-17-26)37-31(40)27-18-12-8-13-19-27/h7-8,10-13,16-19,24-25,28-29H,9,14-15,20-23H2,1-6H3,(H3-,34,35,36,37,39,40,41,42)/p+1/t25-,28-,29-/m0/s1
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n/an/a>6.00E+4n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human N-terminal His-tagged CBX5 chromodomain (18 to 75 residues) expressed in Escherichia coli Rosetta BL21(DE3)p...


J Med Chem 59: 8913-8923 (2016)

More data for this
Ligand-Target Pair
Chromobox protein homolog 5


(Homo sapiens)
BDBM50194448
PNG
(CHEMBL3972289)
Show SMILES CCCN(CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccc(cc1)C(C)(C)C)C(=O)N[C@@H](CO)C(=O)OC)C(C)C
Show InChI InChI=1S/C45H70N6O8/c1-11-24-51(30(4)5)25-16-15-19-35(41(55)50-38(28-52)44(58)59-10)47-43(57)36(26-29(2)3)48-39(53)31(6)46-42(56)37(27-32-17-13-12-14-18-32)49-40(54)33-20-22-34(23-21-33)45(7,8)9/h12-14,17-18,20-23,29-31,35-38,52H,11,15-16,19,24-28H2,1-10H3,(H,46,56)(H,47,57)(H,48,53)(H,49,54)(H,50,55)/t31-,35-,36-,37-,38-/m0/s1
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n/an/a>6.00E+4n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human N-terminal His-tagged CBX5 chromodomain (18 to 75 residues) expressed in Escherichia coli Rosetta BL21(DE3)p...


J Med Chem 59: 8913-8923 (2016)

More data for this
Ligand-Target Pair
Chromobox protein homolog 5


(Homo sapiens)
BDBM50194250
PNG
(CHEMBL3985510)
Show SMILES COC(=O)[C@H](CO)NC(=O)[C@H](CCCCN1CCCCCC1)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)c1ccccc1
Show InChI InChI=1S/C43H63N7O9/c1-29(2)25-34(42(57)47-33(40(55)49-36(28-51)43(58)59-4)21-13-16-24-50-22-14-5-6-15-23-50)48-38(53)30(3)45-41(56)35(26-31-17-9-7-10-18-31)46-37(52)27-44-39(54)32-19-11-8-12-20-32/h7-12,17-20,29-30,33-36,51H,5-6,13-16,21-28H2,1-4H3,(H,44,54)(H,45,56)(H,46,52)(H,47,57)(H,48,53)(H,49,55)/t30-,33-,34-,35-,36-/m0/s1
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n/an/a>6.00E+4n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human N-terminal His-tagged CBX5 chromodomain (18 to 75 residues) expressed in Escherichia coli Rosetta BL21(DE3)p...


J Med Chem 59: 8913-8923 (2016)

More data for this
Ligand-Target Pair
Chromobox protein homolog 5


(Homo sapiens)
BDBM50194252
PNG
(CHEMBL3922982)
Show SMILES COC(=O)[C@H](CO)NC(=O)[C@H](CCCCN(C1CC2CCC1C2)C(C)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)c1ccccc1
Show InChI InChI=1S/C46H65N7O10/c1-28(2)22-36(45(61)50-35(43(59)52-38(27-54)46(62)63-5)18-12-13-21-53(30(4)55)39-25-32-19-20-34(39)23-32)51-41(57)29(3)48-44(60)37(24-31-14-8-6-9-15-31)49-40(56)26-47-42(58)33-16-10-7-11-17-33/h6-11,14-17,28-29,32,34-39,54H,12-13,18-27H2,1-5H3,(H,47,58)(H,48,60)(H,49,56)(H,50,61)(H,51,57)(H,52,59)/t29-,32?,34?,35-,36-,37-,38-,39?/m0/s1
PDB

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PC sid
UniChem
Article
PubMed
n/an/a>6.00E+4n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human N-terminal His-tagged CBX5 chromodomain (18 to 75 residues) expressed in Escherichia coli Rosetta BL21(DE3)p...


J Med Chem 59: 8913-8923 (2016)

More data for this
Ligand-Target Pair
Chromobox protein homolog 5


(Homo sapiens)
BDBM50194253
PNG
(CHEMBL3946489)
Show SMILES COC(=O)[C@H](CO)NC(=O)[C@H](CCCCNC(N(C)C)=[N+](C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)c1ccccc1
Show InChI InChI=1S/C42H63N9O9/c1-27(2)23-32(40(58)47-31(38(56)49-34(26-52)41(59)60-8)21-15-16-22-43-42(50(4)5)51(6)7)48-36(54)28(3)45-39(57)33(24-29-17-11-9-12-18-29)46-35(53)25-44-37(55)30-19-13-10-14-20-30/h9-14,17-20,27-28,31-34,52H,15-16,21-26H2,1-8H3,(H6,44,45,46,47,48,49,53,54,55,56,57,58)/p+1/t28-,31-,32-,33-,34-/m0/s1
PDB

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PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>6.00E+4n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human N-terminal His-tagged CBX5 chromodomain (18 to 75 residues) expressed in Escherichia coli Rosetta BL21(DE3)p...


J Med Chem 59: 8913-8923 (2016)

More data for this
Ligand-Target Pair