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Found 35 of ki for UniProtKB: P08575
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM199180(US9217012, 10)
Affinity DataKi: >1.00E+3nM ΔG°: >-8.18kcal/molepH: 7.0 T: 2°CAssay Description:PTP activity was assayed using p-nitrophenyl phosphate (pNPP) as a substrate in DMG buffer (50 mM DMG, pH 7.0, 1 mM EDTA, 150 mM NaCl, 2 mM DTT, 0.1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50131547(2-(N-(4-(2-acetamido-3-(4-(5-chloro-3-hydroxy-2-(m...)
Affinity DataKi: >3.00E+3nMAssay Description:Inhibitory activity against CD45 tyrosine phosphatase was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM26104(5-{2-cyclohexyl-4-[4-fluoro-3-(trifluoromethyl)phe...)
Affinity DataKi:  7.70E+3nM ΔG°:  -6.90kcal/molepH: 7.4 T: 2°CAssay Description:The reaction was started by addition of pNPP substrate, and reaction progress was monitored at 405 nm. The initial rate data collected was used for d...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50069998(Ammonium; [7-(difluoro-phosphono-methyl)-naphthale...)
Affinity DataKi:  9.00E+3nMAssay Description:Compound was evaluated for inhibitory constant against CD45More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50331945(Asp-BrPmp-Leu | CHEMBL1289231)
Affinity DataKi:  1.60E+4nMAssay Description:Inhibition of human CD45-cytoplasmic domain at 35 uM after 10 mins by Kitz-Wilson analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50118751(6-(Oxalyl-amino)-1H-indole-7-carboxylic acid | 6-(...)
Affinity DataKi:  2.00E+4nMAssay Description:Inhibition of PTPRCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50132460(2-[4-((S)-2-tert-Butoxycarbonylamino-3-{4-[(2-carb...)
Affinity DataKi: >3.00E+4nMAssay Description:Inhibitory potency against CD45 PhosphataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50132461(2-(4-{2-tert-Butoxycarbonylamino-2-[4-(3-hydroxy-2...)
Affinity DataKi: >3.00E+4nMAssay Description:Inhibitory potency against CD45 PhosphataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50132465(5-{(S)-2-((S)-2-tert-Butoxycarbonylamino-3-phenyl-...)
Affinity DataKi: >3.00E+4nMAssay Description:Inhibitory potency against CD45 PhosphataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM14267(4-bromo-3-(carboxymethoxy)-5-[4-(2-formamidoacetic...)
Affinity DataKi:  3.30E+4nMAssay Description:Inhibition of PTPRCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50299462(2-(3-(dihydroxymethyl)naphthalen-2-ylamino)-2-oxoa...)
Affinity DataKi:  3.70E+4nMAssay Description:Inhibition of PTPRCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50331944(CHEMBL1288332 | L-BrPmp-OH)
Affinity DataKi:  4.00E+4nMAssay Description:Inhibition of human CD45-cytoplasmic domain at 150 uM after 10 mins by Kitz-Wilson analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50118762(2-(Oxalyl-amino)-4,5,6,7-tetrahydro-benzo[b]thioph...)
Affinity DataKi:  4.10E+4nMAssay Description:Inhibition of PTPRCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50118778(5-iodo-2-(oxaloamino)benzoic acid | CHEMBL336908)
Affinity DataKi:  4.90E+4nMAssay Description:Inhibition of PTPRCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50118744(2-(Oxalyl-amino)-4,7-dihydro-5H-thieno[2,3-c]pyran...)
Affinity DataKi:  5.30E+4nMAssay Description:Inhibition of PTPRCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM14258(4-bromo-3-(carboxymethoxy)-5-[4-(pyridine-3-amido)...)
Affinity DataKi:  5.50E+4nMAssay Description:Inhibition of PTPRCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50118796(6-(OXALYL-AMINO)-1H-INDOLE-5-CARBOXYLIC ACID | 6-(...)
Affinity DataKi:  5.60E+4nMAssay Description:Inhibition of PTPRCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50118792(2-(OXALYL-AMINO)-4,5,6,7-TETRAHYDRO-THIENO[2,3-C]P...)
Affinity DataKi:  5.90E+4nMAssay Description:Inhibition of PTPRCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM14255(4-bromo-3-(carboxymethoxy)-5-[4-(dimethylamino)phe...)
Affinity DataKi:  6.40E+4nMAssay Description:Inhibition of PTPRCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50219566(4-bromo-3-carboxymethoxy-5-[3-(1-phenylmethanesulf...)
Affinity DataKi:  7.70E+4nMAssay Description:Inhibition of human recombinant CD45More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50312261((4-(4-bromo-3,5-bis(trifluoromethyl)phenylcarbamoy...)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human CD45More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50219573(4-BROMO-3-(CARBOXYMETHOXY)-5-{3-[(3,3,5,5-TETRAMET...)
Affinity DataKi:  1.51E+5nMAssay Description:Inhibition of human recombinant CD45More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50219573(4-BROMO-3-(CARBOXYMETHOXY)-5-{3-[(3,3,5,5-TETRAMET...)
Affinity DataKi:  1.51E+5nMAssay Description:Inhibition of PTPRCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50118789(2-(oxaloamino)benzoic acid | CHEMBL139050)
Affinity DataKi:  1.60E+5nMAssay Description:Inhibition of PTPRCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50131545((S)-2-(N-(4-(2-(allyloxycarbonylamino)-3-(4-(3-hyd...)
Affinity DataKi: >2.00E+5nMAssay Description:Inhibitory activity against CD45 tyrosine phosphatase was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50118749(2-(Oxalyl-amino)-thiophene-3-carboxylic acid | 2-(...)
Affinity DataKi:  2.10E+5nMAssay Description:Inhibition of PTPRCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50118779(3-(Oxalyl-amino)-thiophene-2-carboxylic acid | 3-(...)
Affinity DataKi:  2.60E+5nMAssay Description:Inhibition of PTPRCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50441296(CHEMBL2431665 | CHEMBL2431667)
Affinity DataKi:  2.70E+5nMAssay Description:Inhibition of human CD45 using pNPP as substrate after 5 mins by spectrophotometric plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM14245(4-bromo-3-(carboxymethoxy)-5-phenylthiophene-2-car...)
Affinity DataKi:  2.80E+5nMAssay Description:Inhibition of PTPRCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM14245(4-bromo-3-(carboxymethoxy)-5-phenylthiophene-2-car...)
Affinity DataKi:  2.80E+5nMAssay Description:Inhibition of human recombinant CD45More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50441297(CHEMBL2431664 | CHEMBL2431666)
Affinity DataKi:  3.40E+5nMAssay Description:Inhibition of human CD45 using pNPP as substrate after 5 mins by spectrophotometric plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50299461((S)-7-(1,1-Dioxo-1H-1lambda*6*-benzo[d]isothiazol-...)
Affinity DataKi:  4.89E+5nMAssay Description:Inhibition of PTPRCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50441298(CHEMBL2431708)
Affinity DataKi: >5.00E+5nMAssay Description:Inhibition of human CD45 using pNPP as substrate after 5 mins by spectrophotometric plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM14230(5-(carboxymethoxy)-3,7-dithiatricyclo[6.4.0.0^{2,6...)
Affinity DataKi: >1.25E+6nMAssay Description:Inhibition of PTPRCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50118750(2-(Oxalyl-amino)-6-phenethyl-4,5,6,7-tetrahydro-th...)
Affinity DataKi:  1.40E+6nMpH: 7.0Assay Description:Inhibitory effect against human CD45 tyrosine phosphatase using p-nitrophenyl phosphate substrate at a pH 7.0More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed