Compile Data Set for Download or QSAR
(2D       Computed 3D by Vconf -m prep )

Data curated solely by BindingDB

Found 30 hits of affinity data for UniProtKB/TrEMBL: P04409

Target (Institution)	Ligand	Target Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	pH	Temp °C
Protein Kinase C, alpha Bos taurus (bovine)	4-(Phenylamino)pyrazolo[3,4-d]pyrimidine deriv. 15 (3-((3-Hydroxyphenyl)amino)-4-((3-chlorophenyl)amin...)	GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt	CSLS PC cid PC sid	PubMed	n/a	n/a	560.0	n/a	n/a	7.5	n/a
Novartis Pharmaceuticals					J Med Chem. 40: 3601-16 (1997)
Protein Kinase C, alpha Bos taurus (bovine)	4-(Phenylamino)pyrazolo[3,4-d]pyrimidine deriv. 17 (3-((4-Aminophenyl)amino)-4-((3-chlorophenyl)amino)...)	GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt	CSLS PC cid PC sid	PubMed	n/a	n/a	>1000.0	n/a	n/a	7.5	n/a
Novartis Pharmaceuticals					J Med Chem. 40: 3601-16 (1997)
Protein Kinase C, alpha Bos taurus (bovine)	4-(Phenylamino)pyrazolo[3,4-d]pyrimidine deriv. 13 (3-((4-Hydroxyphenyl)amino)-4-((3-chlorophenyl)amin...)	GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt	CSLS PC cid PC sid	PubMed	n/a	n/a	>1000.0	n/a	n/a	7.5	n/a
Novartis Pharmaceuticals					J Med Chem. 40: 3601-16 (1997)
Protein Kinase C, alpha Bos taurus (bovine)	4-(Phenylamino)pyrazolo[3,4-d]pyrimidine deriv. 28 (3-(3-Aminophenyl)-4-((3-chlorophenyl)amino)-1H-pyr...)	GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt	CSLS PC cid PC sid	PubMed	n/a	n/a	1500.0	n/a	n/a	7.5	n/a
Novartis Pharmaceuticals					J Med Chem. 40: 3601-16 (1997)
Protein Kinase C, alpha Bos taurus (bovine)	4-(Phenylamino)pyrazolo[3,4-d]pyrimidine deriv. 26 (3-(4-Hydroxyphenyl)-4-((3-chlorophenyl)amino)pyraz...)	GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt	CSLS PC cid PC sid	PubMed	n/a	n/a	1850.0	n/a	n/a	7.5	n/a
Novartis Pharmaceuticals					J Med Chem. 40: 3601-16 (1997)
Protein Kinase C, alpha Bos taurus (bovine)	4-(Phenylamino)pyrazolo[3,4-d]pyrimidine deriv. 18 (3-((4-(Dimethylamino)phenyl)amino)-4-((3-chlorophe...)	GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt	CSLS PC cid PC sid	PubMed	n/a	n/a	2900.0	n/a	n/a	7.5	n/a
Novartis Pharmaceuticals					J Med Chem. 40: 3601-16 (1997)
Protein Kinase C, alpha Bos taurus (bovine)	4-(Phenylamino)pyrazolo[3,4-d]pyrimidine deriv. 30 (3-(4-Aminophenyl)-4-((3-chlorophenyl)amino)-1H-pyr...)	GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt	CSLS PC cid PC sid	PubMed	n/a	n/a	3600.0	n/a	n/a	7.5	n/a
Novartis Pharmaceuticals					J Med Chem. 40: 3601-16 (1997)
Protein Kinase C, alpha Bos taurus (bovine)	4-(Phenylamino)pyrazolo[3,4-d]pyrimidine deriv. 10 (3-((3-Chlorophenyl)amino)-4-((3-bromophenyl)amino)...)	GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt	CSLS PC cid PC sid	PubMed	n/a	n/a	3800.0	n/a	n/a	7.5	n/a
Novartis Pharmaceuticals					J Med Chem. 40: 3601-16 (1997)
Protein Kinase C, alpha Bos taurus (bovine)	4-(Phenylamino)pyrazolo[3,4-d]pyrimidine deriv. 32 (3-((3-Chlorophenyl)amino)-4-(benzylamino)-1H-pyraz...)	GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt	CSLS PC cid PC sid	PubMed	n/a	n/a	4500.0	n/a	n/a	7.5	n/a
Novartis Pharmaceuticals					J Med Chem. 40: 3601-16 (1997)
Protein Kinase C, alpha Bos taurus (bovine)	4-(Phenylamino)pyrazolo[3,4-d]pyrimidine deriv. 14 (3-((3-Methoxyphenyl)amino)-4-((3-chlorophenyl)amin...)	GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt	CSLS PC cid PC sid	PubMed	n/a	n/a	4700.0	n/a	n/a	7.5	n/a
Novartis Pharmaceuticals					J Med Chem. 40: 3601-16 (1997)
Protein Kinase C, alpha Bos taurus (bovine)	4-(Phenylamino)pyrazolo[3,4-d]pyrimidine deriv. 11 (3-((3-Chlorophenyl)amino)-4-((3-methylphenyl)amino...)	GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt	CSLS PC cid PC sid	PubMed	n/a	n/a	4700.0	n/a	n/a	7.5	n/a
Novartis Pharmaceuticals					J Med Chem. 40: 3601-16 (1997)
Protein Kinase C, alpha Bos taurus (bovine)	4-(Phenylamino)pyrazolo[3,4-d]pyrimidine deriv. 9 (3,4-Bis((3-chlorophenyl)amino)-1H-pyrazolo[3,4-d]p...)	GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt	CSLS PC cid PC sid	PubMed	n/a	n/a	5900.0	n/a	n/a	7.5	n/a
Novartis Pharmaceuticals					J Med Chem. 40: 3601-16 (1997)
Protein Kinase C, alpha Bos taurus (bovine)	4-(Phenylamino)pyrazolo[3,4-d]pyrimidine deriv. 7 (3,4-Di-(phenylamino)-1H-pyrazolo[3,4-d]pyrimidine ...)	GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt	CSLS PC cid PC sid	PubMed	n/a	n/a	6900.0	n/a	n/a	7.5	n/a
Novartis Pharmaceuticals					J Med Chem. 40: 3601-16 (1997)
Protein Kinase C, alpha Bos taurus (bovine)	4-(Phenylamino)pyrazolo[3,4-d]pyrimidine deriv. 8 (3-((3-Chlorophenyl)amino)-4-(phenylamino)-1H-pyraz...)	GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt	CSLS PC cid PC sid	PubMed	n/a	n/a	7800.0	n/a	n/a	7.5	n/a
Novartis Pharmaceuticals					J Med Chem. 40: 3601-16 (1997)
Protein Kinase C, alpha Bos taurus (bovine)	4-(Phenylamino)pyrazolo[3,4-d]pyrimidine deriv. 20 (3-((3-Chlorobenzyl)amino)-4-((3-chlorophenyl)amino...)	GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt	CSLS PC cid PC sid	PubMed	n/a	n/a	>10000.0	n/a	n/a	7.5	n/a
Novartis Pharmaceuticals					J Med Chem. 40: 3601-16 (1997)
Protein Kinase C, alpha Bos taurus (bovine)	4-(Phenylamino)pyrazolo[3,4-d]pyrimidine deriv. 19 (3-(Benzylamino)-4-((3-chlorophenyl)amino)-1H-pyraz...)	GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt	CSLS PC cid PC sid	PubMed	n/a	n/a	10000.0	n/a	n/a	7.5	n/a
Novartis Pharmaceuticals					J Med Chem. 40: 3601-16 (1997)
Protein Kinase C, alpha Bos taurus (bovine)	4-(Phenylamino)pyrazolo[3,4-d]pyrimidine deriv. 16 (3-((4-(N-BOC-amino)phenyl)amino)-4-((3-chloropheny...)	GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt	CSLS PC cid PC sid	PubMed	n/a	n/a	>10000.0	n/a	n/a	7.5	n/a
Novartis Pharmaceuticals					J Med Chem. 40: 3601-16 (1997)
Protein Kinase C, alpha Bos taurus (bovine)	4-(Phenylamino)pyrazolo[3,4-d]pyrimidine deriv. 23 (N-(3-chlorophenyl)-3-phenyl-1H-pyrazolo[3,4-d]pyri...)	GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt	CSLS PC cid PC sid	PubMed	n/a	n/a	>10000.0	n/a	n/a	7.5	n/a
Novartis Pharmaceuticals					J Med Chem. 40: 3601-16 (1997)
Protein Kinase C, alpha Bos taurus (bovine)	4-(Phenylamino)pyrazolo[3,4-d]pyrimidine deriv. 29 (3-(4-(BOC-amino)phenyl)-4-((3-chlorophenyl)amino)-...)	GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt	CSLS PC cid PC sid	PubMed	n/a	n/a	>10000.0	n/a	n/a	7.5	n/a
Novartis Pharmaceuticals					J Med Chem. 40: 3601-16 (1997)
Protein Kinase C, alpha Bos taurus (bovine)	4-(Phenylamino)pyrazolo[3,4-d]pyrimidine deriv. 25 (3-(4-Methoxyphenyl)-4-((3-chlorophenyl)amino)-1H-p...)	GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt	CSLS PC cid PC sid	PubMed	n/a	n/a	>10000.0	n/a	n/a	7.5	n/a
Novartis Pharmaceuticals					J Med Chem. 40: 3601-16 (1997)
Protein Kinase C, alpha Bos taurus (bovine)	4-(Phenylamino)pyrazolo[3,4-d]pyrimidine deriv. 24 (3-{4-[(3-chlorophenyl)amino]-1H-pyrazolo[3,4-d]pyr...)	GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt	CSLS PC cid PC sid	PubMed	n/a	n/a	>10000.0	n/a	n/a	7.5	n/a
Novartis Pharmaceuticals					J Med Chem. 40: 3601-16 (1997)
Protein Kinase C, alpha Bos taurus (bovine)	4-(Phenylamino)pyrazolo[3,4-d]pyrimidine deriv. 12 (3-((4-Methoxyphenyl)-amino)-4-((3-chlorophenyl)ami...)	GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt	CSLS PC cid PC sid	PubMed	n/a	n/a	19000.0	n/a	n/a	7.5	n/a
Novartis Pharmaceuticals					J Med Chem. 40: 3601-16 (1997)
Protein Kinase C, alpha Bos taurus (bovine)	pyrazolopyrimidine deriv. 6 (3-((3-Chlorophenyl)amino)-4-amino-1H-pyrazolo[3,4-...)	GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt	CSLS PC cid PC sid	PubMed	n/a	n/a	24000.0	n/a	n/a	7.5	n/a
Novartis Pharmaceuticals					J Med Chem. 40: 3601-16 (1997)
Protein Kinase C, alpha Bos taurus (bovine)	pyrazolopyrimidine deriv. 2 (3-((3-Chlorophenyl)amino)-4,6-diamino-1H-pyrazolo[...)	GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt	CSLS PC cid PC sid	PubMed	n/a	n/a	>100000.0	n/a	n/a	7.5	n/a
Novartis Pharmaceuticals					J Med Chem. 40: 3601-16 (1997)
Protein Kinase C, alpha Bos taurus (bovine)	4-(Phenylamino)pyrazolo[3,4-d]pyrimidine deriv. 21 (3-((3-Methoxybenzyl)amino)-4-((3-chlorophenyl)amin...)	GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt	CSLS PC cid PC sid	PubMed	n/a	n/a	>100000.0	n/a	n/a	7.5	n/a
Novartis Pharmaceuticals					J Med Chem. 40: 3601-16 (1997)
Protein Kinase C, alpha Bos taurus (bovine)	pyrazolopyrimidine deriv. 1 (1,3-diphenyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine)	GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt	CHEBI CSLS PC cid PC sid	PubMed	n/a	n/a	>100000.0	n/a	n/a	7.5	n/a
Novartis Pharmaceuticals					J Med Chem. 40: 3601-16 (1997)
Protein Kinase C, alpha Bos taurus (bovine)	4-(Phenylamino)pyrazolo[3,4-d]pyrimidine deriv. 22 (3-((4-Methoxybenzyl)amino)-4-((3-chlorophenyl)amin...)	GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt	CSLS PC cid PC sid	PubMed	n/a	n/a	>100000.0	n/a	n/a	7.5	n/a
Novartis Pharmaceuticals					J Med Chem. 40: 3601-16 (1997)
Protein Kinase C, alpha Bos taurus (bovine)	4-(Phenylamino)pyrazolo[3,4-d]pyrimidine deriv. 27 (3-(3-Nitrophenyl)-4-((3-chlorophenyl)amino)-1H-pyr...)	GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt	CSLS PC cid PC sid	PubMed	n/a	n/a	>100000.0	n/a	n/a	7.5	n/a
Novartis Pharmaceuticals					J Med Chem. 40: 3601-16 (1997)
Protein Kinase C, alpha Bos taurus (bovine)	4-(Phenylamino)pyrazolo[3,4-d]pyrimidine deriv. 31 (4-(3-chlorophenoxy)-N-(3-chlorophenyl)-1H-pyrazolo...)	GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt	CSLS PC cid PC sid	PubMed	n/a	n/a	>100000.0	n/a	n/a	7.5	n/a
Novartis Pharmaceuticals					J Med Chem. 40: 3601-16 (1997)
Protein Kinase C, alpha Bos taurus (bovine)	PD153035 (N-(3-bromophenyl)-6,7-dimethoxyquinazolin-4-amine)	GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt	CHEBI CSLS PC cid PC sid	PubMed	n/a	n/a	>100000.0	n/a	n/a	7.5	n/a
Novartis Pharmaceuticals					J Med Chem. 40: 3601-16 (1997)

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• Change energy unit to:  kcal/mole