Compile Data Set for Download or QSAR
maximum 50k data
Found 800 of ki for UniProtKB: Q9NWZ3
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50499195(CHEMBL3735504)
Affinity DataKi:  0.340nMAssay Description:Inhibition of recombinant full length IRAK-4 (unknown origin) using the biotinylated substrate RRRVTSPARRS by chemiluminescent ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50499203(CHEMBL3736036)
Affinity DataKi:  0.420nMAssay Description:Inhibition of recombinant full length IRAK-4 (unknown origin) using the biotinylated substrate RRRVTSPARRS by chemiluminescent ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50499205(CHEMBL3734814)
Affinity DataKi:  0.480nMAssay Description:Inhibition of recombinant full length IRAK-4 (unknown origin) using the biotinylated substrate RRRVTSPARRS by chemiluminescent ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50499208(CHEMBL3734872)
Affinity DataKi:  0.5nMAssay Description:Inhibition of recombinant full length IRAK-4 (unknown origin) using the biotinylated substrate RRRVTSPARRS by chemiluminescent ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50514930(CHEMBL4464832)
Affinity DataKi:  0.5nMAssay Description:Inhibition of human recombinant full length His6-tagged IRAK4 expressed in baculovirus expression system using H-KKARFSRFAGSSPSQSSMVAR as substrate i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50514929(CHEMBL4474636)
Affinity DataKi:  0.5nMAssay Description:Inhibition of human recombinant full length His6-tagged IRAK4 expressed in baculovirus expression system using H-KKARFSRFAGSSPSQSSMVAR as substrate i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM494431((R)-N-(6-cyclopropyl-2- (2-fluoro-3-hydroxy-3- met...)
Affinity DataKi:  0.610nMAssay Description:Kinase activities were assayed using the Transcreener-Fluorecescence polarization platform (BelBrook Labs, Madison, Wis., USA) that measures amounts ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM494507((R)-N-(6- (dimethylamino)-2-(2- fluoro-3-hydroxy-3...)
Affinity DataKi:  0.630nMAssay Description:Kinase activities were assayed using the Transcreener-Fluorecescence polarization platform (BelBrook Labs, Madison, Wis., USA) that measures amounts ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM480659(N-[6-morpholino-1-oxo-2-[rac- (2R)-2-fluoro-3-hydr...)
Affinity DataKi:  0.680nMAssay Description:Kinase activities were assayed using the Transcreener-Fluorecescence polarization platform (BelBrook Labs, Madison, Wis., USA) that measures amounts ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50499194(CHEMBL3734854)
Affinity DataKi:  0.700nMAssay Description:Inhibition of recombinant full length IRAK-4 (unknown origin) using the biotinylated substrate RRRVTSPARRS by chemiluminescent ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50514924(CHEMBL4568867)
Affinity DataKi:  0.800nMAssay Description:Inhibition of human recombinant full length His6-tagged IRAK4 expressed in baculovirus expression system using H-KKARFSRFAGSSPSQSSMVAR as substrate i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM480678(N-[6-isopropoxy-1-oxo-2-[rac- (2R)-2-fluoro-3-hydr...)
Affinity DataKi:  0.820nMAssay Description:Kinase activities were assayed using the Transcreener-Fluorecescence polarization platform (BelBrook Labs, Madison, Wis., USA) that measures amounts ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM494440((R)-N-(6- (cyclopropylmethoxy)-2- (2-fluoro-3-hydr...)
Affinity DataKi:  0.830nMAssay Description:Kinase activities were assayed using the Transcreener-Fluorecescence polarization platform (BelBrook Labs, Madison, Wis., USA) that measures amounts ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50040805(CHEMBL3361255)
Affinity DataKi:  1nMAssay Description:Inhibition of N-terminal GST-fused full-length human IRAK4 (1 to 460 amino acids) assessed as reduction in phosphorylated substrates by Caliper assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM494075(US10988478, Example 120)
Affinity DataKi:  1nMAssay Description:Kinase activities were assayed using the Transcreener-Fluorecescence polarization platform (BelBrook Labs, Madison, Wis., USA) that measures amounts ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM494349(US10988478, Example 400)
Affinity DataKi:  1nMAssay Description:Kinase activities were assayed using the Transcreener-Fluorecescence polarization platform (BelBrook Labs, Madison, Wis., USA) that measures amounts ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM493978(N-[6-[4-fluoro-4-(hydroxymethyl)-1- piperidyl]-2,2...)
Affinity DataKi:  1nMAssay Description:Kinase activities were assayed using the Transcreener-Fluorecescence polarization platform (BelBrook Labs, Madison, Wis., USA) that measures amounts ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM480682(N-[6-morpholino-1-oxo-2-[rac- (2R)-2-fluoro-3-hydr...)
Affinity DataKi:  1.10nMAssay Description:Kinase activities were assayed using the Transcreener-Fluorecescence polarization platform (BelBrook Labs, Madison, Wis., USA) that measures amounts ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50514935(CHEMBL4520118 | US10988478, Example 491)
Affinity DataKi:  1.10nMAssay Description:Inhibition of human recombinant full length His6-tagged IRAK4 expressed in baculovirus expression system using H-KKARFSRFAGSSPSQSSMVAR as substrate i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM494453(N-(6-(4-((1H-imidazol-4- yl)-2,2-dimethyl-2,3- yl)...)
Affinity DataKi:  1.10nMAssay Description:Kinase activities were assayed using the Transcreener-Fluorecescence polarization platform (BelBrook Labs, Madison, Wis., USA) that measures amounts ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM494463((S)-N-(3-(cyanomethyl)- 3-methyl-7- morpholinochro...)
Affinity DataKi:  1.10nMAssay Description:Kinase activities were assayed using the Transcreener-Fluorecescence polarization platform (BelBrook Labs, Madison, Wis., USA) that measures amounts ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM480668(N-[6-(dimethylamino)-1-oxo- 2-[rac-(2R)-2-fluoro-3...)
Affinity DataKi:  1.10nMAssay Description:Kinase activities were assayed using the Transcreener-Fluorecescence polarization platform (BelBrook Labs, Madison, Wis., USA) that measures amounts ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50514935(CHEMBL4520118 | US10988478, Example 491)
Affinity DataKi:  1.10nMAssay Description:Kinase activities were assayed using the Transcreener-Fluorecescence polarization platform (BelBrook Labs, Madison, Wis., USA) that measures amounts ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50514941(CHEMBL4515682)
Affinity DataKi:  1.20nMAssay Description:Inhibition of human recombinant full length His6-tagged IRAK4 expressed in baculovirus expression system using H-KKARFSRFAGSSPSQSSMVAR as substrate i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50040726(CHEMBL1236126)
Affinity DataKi:  1.20nMAssay Description:Inhibition of IRAK4 (unknown origin)More data for this Ligand-Target Pair
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50499197(CHEMBL3736465)
Affinity DataKi:  1.30nMAssay Description:Inhibition of recombinant full length IRAK-4 (unknown origin) using the biotinylated substrate RRRVTSPARRS by chemiluminescent ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM494338(US10988478, Example 389)
Affinity DataKi:  1.30nMAssay Description:Kinase activities were assayed using the Transcreener-Fluorecescence polarization platform (BelBrook Labs, Madison, Wis., USA) that measures amounts ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM480719(N-(2,2-dimethyl-6-morpholino- 3H-benzofuran-5-yl)-...)
Affinity DataKi:  1.40nMAssay Description:Kinase activities were assayed using the Transcreener-Fluorecescence polarization platform (BelBrook Labs, Madison, Wis., USA) that measures amounts ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50511349(CHEMBL4475494 | US10988478, Example 139)
Affinity DataKi:  1.40nMAssay Description:Inhibition of recombinant full-length N-terminal His6-tagged human IRAK4 expressed in baculovirus expression system using H-KKARFSRFAGSSPSQSSMVAR pep...More data for this Ligand-Target Pair
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM494225((R)-N-(6-(4-cyanopiperidin- 1-yl)-2-(2-fluoro-3-hy...)
Affinity DataKi:  1.40nMAssay Description:Kinase activities were assayed using the Transcreener-Fluorecescence polarization platform (BelBrook Labs, Madison, Wis., USA) that measures amounts ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM494320(N-(6-(4- (Hydroxymethyl) piperidin-1-yl)- 1'-methy...)
Affinity DataKi:  1.40nMAssay Description:Kinase activities were assayed using the Transcreener-Fluorecescence polarization platform (BelBrook Labs, Madison, Wis., USA) that measures amounts ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50511349(CHEMBL4475494 | US10988478, Example 139)
Affinity DataKi:  1.5nMAssay Description:Kinase activities were assayed using the Transcreener-Fluorecescence polarization platform (BelBrook Labs, Madison, Wis., USA) that measures amounts ...More data for this Ligand-Target Pair
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50514919(CHEMBL4467170 | US10988478, Example 4)
Affinity DataKi:  1.5nMAssay Description:Inhibition of human recombinant full length His6-tagged IRAK4 expressed in baculovirus expression system using H-KKARFSRFAGSSPSQSSMVAR as substrate i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM494220(6-Bromo-N-[2-[(2R)-2- fluoro-3-hydroxy-3-methyl- b...)
Affinity DataKi:  1.5nMAssay Description:Kinase activities were assayed using the Transcreener-Fluorecescence polarization platform (BelBrook Labs, Madison, Wis., USA) that measures amounts ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM480669(N-[6-(dimethylamino)-1-oxo- 2-[rac-(2R)-2-fluoro-3...)
Affinity DataKi:  1.5nMAssay Description:Kinase activities were assayed using the Transcreener-Fluorecescence polarization platform (BelBrook Labs, Madison, Wis., USA) that measures amounts ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50514919(CHEMBL4467170 | US10988478, Example 4)
Affinity DataKi:  1.5nMAssay Description:Kinase activities were assayed using the Transcreener-Fluorecescence polarization platform (BelBrook Labs, Madison, Wis., USA) that measures amounts ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM494498(N-(2-(((1R,2R)-2- hydroxycyclopentyl)methyl)- 6-mo...)
Affinity DataKi:  1.60nMAssay Description:Kinase activities were assayed using the Transcreener-Fluorecescence polarization platform (BelBrook Labs, Madison, Wis., USA) that measures amounts ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50499206(CHEMBL3735949)
Affinity DataKi:  1.60nMAssay Description:Inhibition of recombinant full length IRAK-4 (unknown origin) using the biotinylated substrate RRRVTSPARRS by chemiluminescent ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM480743(N-(2,2-dimethyl-6-morpholino- 3H-benzofuran-5-yl)-...)
Affinity DataKi:  1.60nMAssay Description:Kinase activities were assayed using the Transcreener-Fluorecescence polarization platform (BelBrook Labs, Madison, Wis., USA) that measures amounts ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM493983((S)—N-(6-(4-Fluoro-4-(hydroxymethyl)piperidin...)
Affinity DataKi:  1.70nMAssay Description:Kinase activities were assayed using the Transcreener-Fluorecescence polarization platform (BelBrook Labs, Madison, Wis., USA) that measures amounts ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM480671(N-[6-morpholino-1-oxo-2-[rac- (2R)-2-fluoro-3-hydr...)
Affinity DataKi:  1.70nMAssay Description:Kinase activities were assayed using the Transcreener-Fluorecescence polarization platform (BelBrook Labs, Madison, Wis., USA) that measures amounts ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM494222(6-Chloro-N-[2-[(2R)-2- fluoro-3-hydroxy-3-methyl- ...)
Affinity DataKi:  1.70nMAssay Description:Kinase activities were assayed using the Transcreener-Fluorecescence polarization platform (BelBrook Labs, Madison, Wis., USA) that measures amounts ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM494322(N-(6-(4-(2- Amino-2- oxoethyl)piperazin- 1-yl)-1'-...)
Affinity DataKi:  1.70nMAssay Description:Kinase activities were assayed using the Transcreener-Fluorecescence polarization platform (BelBrook Labs, Madison, Wis., USA) that measures amounts ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50514940(CHEMBL4453861)
Affinity DataKi:  1.70nMAssay Description:Inhibition of human recombinant full length His6-tagged IRAK4 expressed in baculovirus expression system using H-KKARFSRFAGSSPSQSSMVAR as substrate i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50514927(CHEMBL4460055)
Affinity DataKi:  1.70nMAssay Description:Inhibition of human recombinant full length His6-tagged IRAK4 expressed in baculovirus expression system using H-KKARFSRFAGSSPSQSSMVAR as substrate i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50514942(CHEMBL4483477)
Affinity DataKi:  1.80nMAssay Description:Inhibition of human recombinant full length His6-tagged IRAK4 expressed in baculovirus expression system using H-KKARFSRFAGSSPSQSSMVAR as substrate i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM494045(US10988478, Example 93)
Affinity DataKi:  1.80nMAssay Description:Kinase activities were assayed using the Transcreener-Fluorecescence polarization platform (BelBrook Labs, Madison, Wis., USA) that measures amounts ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM494230(N-[6-[4-(2,2- Difluoroethyl)piperazin-1- yl]-2-(3-...)
Affinity DataKi:  1.80nMAssay Description:Kinase activities were assayed using the Transcreener-Fluorecescence polarization platform (BelBrook Labs, Madison, Wis., USA) that measures amounts ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM493950(N-[2-(hydroxymethyl)-6-[4- (hydroxymethyl)-1-piper...)
Affinity DataKi:  1.90nMAssay Description:Kinase activities were assayed using the Transcreener-Fluorecescence polarization platform (BelBrook Labs, Madison, Wis., USA) that measures amounts ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50511360(CHEMBL4556091)
Affinity DataKi:  1.90nMAssay Description:Inhibition of recombinant full-length N-terminal His6-tagged human IRAK4 expressed in baculovirus expression system using H-KKARFSRFAGSSPSQSSMVAR pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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