TargetDNA polymerase beta(Homo sapiens (Human))
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Compound was evaluated for the inhibition of cellular DNA polymerase (beta)More data for this Ligand-Target Pair
TargetDNA polymerase beta(Homo sapiens (Human))
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Compound was evaluated for the inhibition of cellular DNA polymerase (beta)More data for this Ligand-Target Pair
TargetDNA polymerase beta(Homo sapiens (Human))
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human recombinant DNA polymerase beta assessed as fluorescein-12-dCTP incorporation by fluorimetryMore data for this Ligand-Target Pair
TargetDNA polymerase beta(Homo sapiens (Human))
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human DNA polymerase-betaMore data for this Ligand-Target Pair
TargetDNA polymerase beta(Homo sapiens (Human))
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human DNA polymerase beta by microplate reader analysisMore data for this Ligand-Target Pair
TargetDNA polymerase beta(Homo sapiens (Human))
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of DNA polymerase betaMore data for this Ligand-Target Pair
TargetDNA polymerase beta(Homo sapiens (Human))
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Affinity DataIC50: 2.20E+3nMAssay Description:Compound was evaluated for the inhibition of cellular DNA polymerase (beta)More data for this Ligand-Target Pair
TargetDNA polymerase beta(Homo sapiens (Human))
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of DNA polymerase betaMore data for this Ligand-Target Pair
TargetDNA polymerase beta(Homo sapiens (Human))
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of DNA polymerase betaMore data for this Ligand-Target Pair
TargetDNA polymerase beta(Homo sapiens (Human))
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of DNA polymerase betaMore data for this Ligand-Target Pair
TargetDNA polymerase beta(Homo sapiens (Human))
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of DNA polymerase betaMore data for this Ligand-Target Pair
TargetDNA polymerase beta(Homo sapiens (Human))
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of DNA polymerase betaMore data for this Ligand-Target Pair
TargetDNA polymerase beta(Homo sapiens (Human))
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of DNA polymerase betaMore data for this Ligand-Target Pair
TargetDNA polymerase beta(Homo sapiens (Human))
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of DNA polymerase betaMore data for this Ligand-Target Pair
TargetDNA polymerase beta(Homo sapiens (Human))
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibition of human DNA polymerase beta using 5-end radiolabeled 24nt to 48nt DNA as primer template after 5 mins in presence of dCTP/dGTP/dTTP/dATP ...More data for this Ligand-Target Pair
TargetDNA polymerase beta(Homo sapiens (Human))
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibition of human DNA polymerase beta using 5-end radiolabeled 24nt to 48nt DNA as primer template after 5 mins in presence of dCTP/dGTP/dTTP/dATP ...More data for this Ligand-Target Pair
TargetDNA polymerase beta(Homo sapiens (Human))
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Affinity DataIC50: 8.70E+3nMAssay Description:Inhibition of DNA polymerase betaMore data for this Ligand-Target Pair
TargetDNA polymerase beta(Homo sapiens (Human))
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Affinity DataIC50: 8.70E+3nMAssay Description:Inhibition of DNA polymerase betaMore data for this Ligand-Target Pair
TargetDNA polymerase beta(Homo sapiens (Human))
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of DNA polymerase betaMore data for this Ligand-Target Pair
TargetDNA polymerase beta(Homo sapiens (Human))
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of DNA polymerase beta (unknown origin) lyase activityMore data for this Ligand-Target Pair
TargetDNA polymerase beta(Homo sapiens (Human))
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of DNA polymerase beta lyase activity by deoxyribose phosphate excision assayMore data for this Ligand-Target Pair
TargetDNA polymerase beta(Homo sapiens (Human))
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of DNA polymerase betaMore data for this Ligand-Target Pair
TargetDNA polymerase beta(Homo sapiens (Human))
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of DNA polymerase beta (unknown origin)More data for this Ligand-Target Pair
TargetDNA polymerase beta(Homo sapiens (Human))
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of DNA polymerase betaMore data for this Ligand-Target Pair
TargetDNA polymerase beta(Homo sapiens (Human))
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory activity against DNA polymerase betaMore data for this Ligand-Target Pair
TargetDNA polymerase beta(Homo sapiens (Human))
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of DNA polymerase betaMore data for this Ligand-Target Pair
TargetDNA polymerase beta(Homo sapiens (Human))
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory activity against DNA polymerase betaMore data for this Ligand-Target Pair
TargetDNA polymerase beta(Homo sapiens (Human))
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory activity against DNA polymerase betaMore data for this Ligand-Target Pair
TargetDNA polymerase beta(Homo sapiens (Human))
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory activity against DNA polymerase betaMore data for this Ligand-Target Pair
TargetDNA polymerase beta(Homo sapiens (Human))
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory activity against DNA polymerase betaMore data for this Ligand-Target Pair
TargetDNA polymerase beta(Homo sapiens (Human))
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory activity against DNA polymerase betaMore data for this Ligand-Target Pair
TargetDNA polymerase beta(Homo sapiens (Human))
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory activity against DNA polymerase betaMore data for this Ligand-Target Pair
TargetDNA polymerase beta(Homo sapiens (Human))
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory activity against DNA polymerase betaMore data for this Ligand-Target Pair
TargetDNA polymerase beta(Homo sapiens (Human))
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory activity against DNA polymerase betaMore data for this Ligand-Target Pair
TargetDNA polymerase beta(Homo sapiens (Human))
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory activity against DNA polymerase betaMore data for this Ligand-Target Pair
TargetDNA polymerase beta(Homo sapiens (Human))
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of human recombinant DNA polymerase beta assessed as fluorescein-12-dCTP incorporation by fluorimetryMore data for this Ligand-Target Pair
TargetDNA polymerase beta(Homo sapiens (Human))
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Affinity DataIC50: 1.23E+4nMAssay Description:Inhibition of DNA polymerase beta (unknown origin) lyase activityMore data for this Ligand-Target Pair
TargetDNA polymerase beta(Homo sapiens (Human))
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Affinity DataIC50: >1.25E+4nMAssay Description:Inhibition of DNA polymerase betaMore data for this Ligand-Target Pair
TargetDNA polymerase beta(Homo sapiens (Human))
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Affinity DataIC50: 1.26E+4nMAssay Description:Inhibition of DNA polymerase beta (unknown origin) lyase activityMore data for this Ligand-Target Pair
TargetDNA polymerase beta(Homo sapiens (Human))
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of DNA polymerase beta lyase activity by deoxyribose phosphate excision assayMore data for this Ligand-Target Pair
TargetDNA polymerase beta(Homo sapiens (Human))
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Affinity DataIC50: 1.35E+4nMAssay Description:Inhibition of human DNA polymerase beta by microplate reader analysisMore data for this Ligand-Target Pair
TargetDNA polymerase beta(Homo sapiens (Human))
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Affinity DataIC50: 1.53E+4nMAssay Description:Inhibition of DNA polymerase beta (unknown origin) lyase activityMore data for this Ligand-Target Pair
TargetDNA polymerase beta(Homo sapiens (Human))
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of DNA polymerase betaMore data for this Ligand-Target Pair
TargetDNA polymerase beta(Homo sapiens (Human))
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Affinity DataIC50: 1.82E+4nMpH: 7.9Assay Description:Pol β reactions were made in a final volume of 20uL containing 50mM Tris-HCl pH 7.9, 20mM KCl, 5% (v/v) glycerol, 1mM DTT, 2mM MnCl2, 250nM puri...More data for this Ligand-Target Pair
TargetDNA polymerase beta(Homo sapiens (Human))
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Affinity DataIC50: 1.86E+4nMAssay Description:Inhibition of DNA polymerase beta (unknown origin) lyase activityMore data for this Ligand-Target Pair
TargetDNA polymerase beta(Homo sapiens (Human))
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Affinity DataIC50: 1.86E+4nMAssay Description:Inhibition of DNA polymerase beta (unknown origin) lyase activityMore data for this Ligand-Target Pair
TargetDNA polymerase beta(Homo sapiens (Human))
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of human DNA polymerase beta using 5' end radiolabeled 24nt DNA/48nt DNA as primer/template after 5 mins by PAGE analysisMore data for this Ligand-Target Pair
TargetDNA polymerase beta(Homo sapiens (Human))
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human DNA polymerase betaMore data for this Ligand-Target Pair
TargetDNA polymerase beta(Homo sapiens (Human))
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human DNA polymerase betaMore data for this Ligand-Target Pair
TargetDNA polymerase beta(Homo sapiens (Human))
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Max-Delbr�ck-Centrum f�r Molekulare Medizin
Curated by ChEMBL
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human DNA polymerase betaMore data for this Ligand-Target Pair