Found 96 hits of ic50 data for polymerid = 5837 Target (Institution) | Ligand | Target Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Kynurenine aminotransferase II (KAT II)
(Homo sapiens (Human)) | BDBM107727
 (US8933095, 11)Show InChI InChI=1S/C14H16N4O3/c1-21-11-4-2-3-9(5-11)7-17-8-10-6-12(15)14(19)18(20)13(10)16-17/h2-5,8,12,20H,6-7,15H2,1H3/t12-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet 
| PC cid PC sid UniChem
Similars AffyNet 
| US Patent
| n/a | n/a | 8.93 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
US Patent
| Assay Description Formation of kynurenic acid (KYNA) is indirectly assessed by a decrease in light absorbance at 370 nm (OD370) as the L-kynurenine (KYN) substrate is ... |
US Patent US8933095 (2015)
|
More data for this Ligand-Target Pair | |
Kynurenine aminotransferase II (KAT II)
(Homo sapiens (Human)) | BDBM107727
 (US8933095, 11)Show InChI InChI=1S/C14H16N4O3/c1-21-11-4-2-3-9(5-11)7-17-8-10-6-12(15)14(19)18(20)13(10)16-17/h2-5,8,12,20H,6-7,15H2,1H3/t12-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet 
| PC cid PC sid UniChem
Similars AffyNet 
| US Patent
| n/a | n/a | 8.93 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
US Patent
| Assay Description Formation of kynurenic acid (KYNA) is indirectly assessed by a decrease in light absorbance at 370 nm (OD370) as the L-kynurenine (KYN) substrate is ... |
US Patent US8598200 (2013)
|
More data for this Ligand-Target Pair | |
Kynurenine aminotransferase II (KAT II)
(Homo sapiens (Human)) | BDBM107721
 (US8933095, 3)Show InChI InChI=1S/C14H16N4O2/c1-17-12(7-9-5-3-2-4-6-9)10-8-11(15)14(19)18(20)13(10)16-17/h2-6,11,20H,7-8,15H2,1H3/t11-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet 
| PC cid PC sid UniChem
Similars AffyNet 
| US Patent
| n/a | n/a | 11.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
US Patent
| Assay Description Formation of kynurenic acid (KYNA) is indirectly assessed by a decrease in light absorbance at 370 nm (OD370) as the L-kynurenine (KYN) substrate is ... |
US Patent US8598200 (2013)
|
More data for this Ligand-Target Pair | |
Kynurenine aminotransferase II (KAT II)
(Homo sapiens (Human)) | BDBM107721
 (US8933095, 3)Show InChI InChI=1S/C14H16N4O2/c1-17-12(7-9-5-3-2-4-6-9)10-8-11(15)14(19)18(20)13(10)16-17/h2-6,11,20H,7-8,15H2,1H3/t11-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet 
| PC cid PC sid UniChem
Similars AffyNet 
| US Patent
| n/a | n/a | 11.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
US Patent
| Assay Description Formation of kynurenic acid (KYNA) is indirectly assessed by a decrease in light absorbance at 370 nm (OD370) as the L-kynurenine (KYN) substrate is ... |
US Patent US8933095 (2015)
|
More data for this Ligand-Target Pair | |
Kynurenine aminotransferase II (KAT II)
(Homo sapiens (Human)) | BDBM50386310
 (CHEMBL2049092)Show InChI InChI=1S/C10H12N2O3/c1-15-7-3-2-6-4-8(11)10(13)12(14)9(6)5-7/h2-3,5,8,14H,4,11H2,1H3/t8-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet 
| CHEMBL PC cid PC sid UniChem
Similars AffyNet 
| Article
| n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human KAT2 using L-kynurenine as substrate measured after 15-20 hrs by SpectraMax plate reader analysis |
Citation and Details
|
More data for this Ligand-Target Pair | |
Kynurenine aminotransferase II (KAT II)
(Homo sapiens (Human)) | BDBM50386310
 (CHEMBL2049092)Show InChI InChI=1S/C10H12N2O3/c1-15-7-3-2-6-4-8(11)10(13)12(14)9(6)5-7/h2-3,5,8,14H,4,11H2,1H3/t8-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet 
| CHEMBL PC cid PC sid UniChem
Similars AffyNet 
| Article
| n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human recombinant KAT2 assessed as conversion of L-kynurenine into kynurenic acid after 15 to 20 hrs |
Citation and Details
|
More data for this Ligand-Target Pair | |
Kynurenine aminotransferase II (KAT II)
(Homo sapiens (Human)) | BDBM107747
 (CHEMBL2347115 | US8933095, 4)Show InChI InChI=1S/C13H14N4O2/c14-10-6-11-12(17(19)13(10)18)7-15-16(11)8-9-4-2-1-3-5-9/h1-5,7,10,19H,6,8,14H2/t10-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet 
| CHEMBL PC cid PC sid UniChem
Similars AffyNet 
| US Patent
| n/a | n/a | 22.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
US Patent
| Assay Description Formation of kynurenic acid (KYNA) is indirectly assessed by a decrease in light absorbance at 370 nm (OD370) as the L-kynurenine (KYN) substrate is ... |
US Patent US8598200 (2013)
|
More data for this Ligand-Target Pair | |
Kynurenine aminotransferase II (KAT II)
(Homo sapiens (Human)) | BDBM107747
 (CHEMBL2347115 | US8933095, 4)Show InChI InChI=1S/C13H14N4O2/c14-10-6-11-12(17(19)13(10)18)7-15-16(11)8-9-4-2-1-3-5-9/h1-5,7,10,19H,6,8,14H2/t10-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet 
| CHEMBL PC cid PC sid UniChem
Similars AffyNet 
| US Patent
| n/a | n/a | 22.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
US Patent
| Assay Description Formation of kynurenic acid (KYNA) is indirectly assessed by a decrease in light absorbance at 370 nm (OD370) as the L-kynurenine (KYN) substrate is ... |
US Patent US8933095 (2015)
|
More data for this Ligand-Target Pair | |
Kynurenine aminotransferase II (KAT II)
(Homo sapiens (Human)) | BDBM50386292
 (CHEMBL2047851)Show InChI InChI=1S/C9H10N2O2/c10-7-5-6-3-1-2-4-8(6)11(13)9(7)12/h1-4,7,13H,5,10H2/t7-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet 
| Purchase
CHEMBL PC cid PC sid UniChem
Similars AffyNet 
| Article
| n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human KAT2 using L-kynurenine as substrate measured after 15-20 hrs by SpectraMax plate reader analysis |
Citation and Details
|
More data for this Ligand-Target Pair | |
Kynurenine aminotransferase II (KAT II)
(Homo sapiens (Human)) | BDBM50426341
 (CHEMBL2321944)Show InChI InChI=1S/C15H14N2O3/c16-13-9-10-8-12(20-11-4-2-1-3-5-11)6-7-14(10)17(19)15(13)18/h1-8,13,19H,9,16H2/t13-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet 
| CHEMBL PC cid PC sid UniChem
Similars AffyNet 
| Article
| n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human KAT2 using L-kynurenine as substrate measured after 15-20 hrs by SpectraMax plate reader analysis |
Citation and Details
|
More data for this Ligand-Target Pair | |
Kynurenine aminotransferase II (KAT II)
(Homo sapiens (Human)) | BDBM107747
 (CHEMBL2347115 | US8933095, 4)Show InChI InChI=1S/C13H14N4O2/c14-10-6-11-12(17(19)13(10)18)7-15-16(11)8-9-4-2-1-3-5-9/h1-5,7,10,19H,6,8,14H2/t10-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet 
| CHEMBL PC cid PC sid UniChem
Similars AffyNet 
| Article PubMed
| n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description Inhibition of human KAT2 using L-kynurenine as substrate after 15 to 20 hrs by UV-visible spectra analysis |
Bioorg Med Chem Lett 23: 1961-6 (2013)
|
More data for this Ligand-Target Pair | |
Kynurenine aminotransferase II (KAT II)
(Homo sapiens (Human)) | BDBM50386292
 (CHEMBL2047851)Show InChI InChI=1S/C9H10N2O2/c10-7-5-6-3-1-2-4-8(6)11(13)9(7)12/h1-4,7,13H,5,10H2/t7-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet 
| Purchase
CHEMBL PC cid PC sid UniChem
Similars AffyNet 
| Article
| n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human recombinant KAT2 assessed as conversion of L-kynurenine into kynurenic acid after 15 to 20 hrs |
Citation and Details
|
More data for this Ligand-Target Pair | |
Kynurenine aminotransferase II (KAT II)
(Homo sapiens (Human)) | BDBM107730
 (CHEMBL2347108 | US8933095, 14)Show InChI InChI=1S/C12H12N4O2/c13-10-6-8-7-15(9-4-2-1-3-5-9)14-11(8)16(18)12(10)17/h1-5,7,10,18H,6,13H2/t10-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet 
| CHEMBL PC cid PC sid UniChem
Similars AffyNet 
| US Patent
| n/a | n/a | 24.3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
US Patent
| Assay Description Formation of kynurenic acid (KYNA) is indirectly assessed by a decrease in light absorbance at 370 nm (OD370) as the L-kynurenine (KYN) substrate is ... |
US Patent US8933095 (2015)
|
More data for this Ligand-Target Pair | |
Kynurenine aminotransferase II (KAT II)
(Homo sapiens (Human)) | BDBM107739
 (US8933095, 23)Show InChI InChI=1S/C15H18N4O2/c1-2-18-13(8-10-6-4-3-5-7-10)11-9-12(16)15(20)19(21)14(11)17-18/h3-7,12,21H,2,8-9,16H2,1H3/t12-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet 
| PC cid PC sid UniChem
Similars AffyNet 
| US Patent
| n/a | n/a | 24.3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
US Patent
| Assay Description Formation of kynurenic acid (KYNA) is indirectly assessed by a decrease in light absorbance at 370 nm (OD370) as the L-kynurenine (KYN) substrate is ... |
US Patent US8933095 (2015)
|
More data for this Ligand-Target Pair | |
Kynurenine aminotransferase II (KAT II)
(Homo sapiens (Human)) | BDBM107739
 (US8933095, 23)Show InChI InChI=1S/C15H18N4O2/c1-2-18-13(8-10-6-4-3-5-7-10)11-9-12(16)15(20)19(21)14(11)17-18/h3-7,12,21H,2,8-9,16H2,1H3/t12-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet 
| PC cid PC sid UniChem
Similars AffyNet 
| US Patent
| n/a | n/a | 24.3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
US Patent
| Assay Description Formation of kynurenic acid (KYNA) is indirectly assessed by a decrease in light absorbance at 370 nm (OD370) as the L-kynurenine (KYN) substrate is ... |
US Patent US8598200 (2013)
|
More data for this Ligand-Target Pair | |
Kynurenine aminotransferase II (KAT II)
(Homo sapiens (Human)) | BDBM107730
 (CHEMBL2347108 | US8933095, 14)Show InChI InChI=1S/C12H12N4O2/c13-10-6-8-7-15(9-4-2-1-3-5-9)14-11(8)16(18)12(10)17/h1-5,7,10,18H,6,13H2/t10-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet 
| CHEMBL PC cid PC sid UniChem
Similars AffyNet 
| US Patent
| n/a | n/a | 24.3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
US Patent
| Assay Description Formation of kynurenic acid (KYNA) is indirectly assessed by a decrease in light absorbance at 370 nm (OD370) as the L-kynurenine (KYN) substrate is ... |
US Patent US8598200 (2013)
|
More data for this Ligand-Target Pair | |
Kynurenine aminotransferase II (KAT II)
(Homo sapiens (Human)) | BDBM107730
 (CHEMBL2347108 | US8933095, 14)Show InChI InChI=1S/C12H12N4O2/c13-10-6-8-7-15(9-4-2-1-3-5-9)14-11(8)16(18)12(10)17/h1-5,7,10,18H,6,13H2/t10-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet 
| CHEMBL PC cid PC sid UniChem
Similars AffyNet 
| Article PubMed
| n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description Inhibition of human KAT2 using L-kynurenine as substrate after 15 to 20 hrs by UV-visible spectra analysis |
Bioorg Med Chem Lett 23: 1961-6 (2013)
|
More data for this Ligand-Target Pair | |
Kynurenine aminotransferase II (KAT II)
(Homo sapiens (Human)) | BDBM107731
 (US8933095, 15)Show InChI InChI=1S/C14H16N4O3/c1-21-11-4-2-9(3-5-11)7-17-8-10-6-12(15)14(19)18(20)13(10)16-17/h2-5,8,12,20H,6-7,15H2,1H3/t12-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet 
| PC cid PC sid UniChem
Similars AffyNet 
| US Patent
| n/a | n/a | 28.3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
US Patent
| Assay Description Formation of kynurenic acid (KYNA) is indirectly assessed by a decrease in light absorbance at 370 nm (OD370) as the L-kynurenine (KYN) substrate is ... |
US Patent US8598200 (2013)
|
More data for this Ligand-Target Pair | |
Kynurenine aminotransferase II (KAT II)
(Homo sapiens (Human)) | BDBM107731
 (US8933095, 15)Show InChI InChI=1S/C14H16N4O3/c1-21-11-4-2-9(3-5-11)7-17-8-10-6-12(15)14(19)18(20)13(10)16-17/h2-5,8,12,20H,6-7,15H2,1H3/t12-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet 
| PC cid PC sid UniChem
Similars AffyNet 
| US Patent
| n/a | n/a | 28.3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
US Patent
| Assay Description Formation of kynurenic acid (KYNA) is indirectly assessed by a decrease in light absorbance at 370 nm (OD370) as the L-kynurenine (KYN) substrate is ... |
US Patent US8933095 (2015)
|
More data for this Ligand-Target Pair | |
Kynurenine aminotransferase II (KAT II)
(Homo sapiens (Human)) | BDBM50386308
 (CHEMBL2047861)Show InChI InChI=1S/C9H9ClN2O2/c10-6-2-1-5-3-7(11)9(13)12(14)8(5)4-6/h1-2,4,7,14H,3,11H2/t7-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet 
| CHEMBL PC cid PC sid UniChem
Similars AffyNet 
| Article
| n/a | n/a | 29 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human recombinant KAT2 assessed as conversion of L-kynurenine into kynurenic acid after 15 to 20 hrs |
Citation and Details
|
More data for this Ligand-Target Pair | |
Kynurenine aminotransferase II (KAT II)
(Homo sapiens (Human)) | BDBM50386294
 (CHEMBL2049095)Show InChI InChI=1S/C10H9F3N2O2/c11-10(12,13)6-1-2-8-5(3-6)4-7(14)9(16)15(8)17/h1-3,7,17H,4,14H2/t7-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet 
| CHEMBL PC cid PC sid UniChem
Similars AffyNet 
| Article
| n/a | n/a | 29 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human recombinant KAT2 assessed as conversion of L-kynurenine into kynurenic acid after 15 to 20 hrs |
Citation and Details
|
More data for this Ligand-Target Pair | |
Kynurenine aminotransferase II (KAT II)
(Homo sapiens (Human)) | BDBM50386312
 (CHEMBL2049094)Show InChI InChI=1S/C10H12N2O2/c1-6-2-3-9-7(4-6)5-8(11)10(13)12(9)14/h2-4,8,14H,5,11H2,1H3/t8-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet 
| Purchase
CHEMBL PC cid PC sid UniChem
Similars AffyNet 
| Article
| n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human recombinant KAT2 assessed as conversion of L-kynurenine into kynurenic acid after 15 to 20 hrs |
Citation and Details
|
More data for this Ligand-Target Pair | |
Kynurenine aminotransferase II (KAT II)
(Homo sapiens (Human)) | BDBM107745
 (US8933095, 29)Show SMILES N[C@H]1Cc2cn(nc2N(O)C1=O)-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C13H11F3N4O2/c14-13(15,16)8-1-3-9(4-2-8)19-6-7-5-10(17)12(21)20(22)11(7)18-19/h1-4,6,10,22H,5,17H2/t10-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet 
| PC cid PC sid UniChem
Similars AffyNet 
| US Patent
| n/a | n/a | 31.6 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
US Patent
| Assay Description Formation of kynurenic acid (KYNA) is indirectly assessed by a decrease in light absorbance at 370 nm (OD370) as the L-kynurenine (KYN) substrate is ... |
US Patent US8933095 (2015)
|
More data for this Ligand-Target Pair | |
Kynurenine aminotransferase II (KAT II)
(Homo sapiens (Human)) | BDBM107745
 (US8933095, 29)Show SMILES N[C@H]1Cc2cn(nc2N(O)C1=O)-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C13H11F3N4O2/c14-13(15,16)8-1-3-9(4-2-8)19-6-7-5-10(17)12(21)20(22)11(7)18-19/h1-4,6,10,22H,5,17H2/t10-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet 
| PC cid PC sid UniChem
Similars AffyNet 
| US Patent
| n/a | n/a | 31.6 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
US Patent
| Assay Description Formation of kynurenic acid (KYNA) is indirectly assessed by a decrease in light absorbance at 370 nm (OD370) as the L-kynurenine (KYN) substrate is ... |
US Patent US8598200 (2013)
|
More data for this Ligand-Target Pair | |
Kynurenine aminotransferase II (KAT II)
(Homo sapiens (Human)) | BDBM107724
 (US8933095, 8)Show InChI InChI=1S/C17H16N4O2/c18-15-8-13-10-20(19-16(13)21(23)17(15)22)9-12-6-3-5-11-4-1-2-7-14(11)12/h1-7,10,15,23H,8-9,18H2/t15-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet 
| PC cid PC sid UniChem
Similars AffyNet 
| US Patent
| n/a | n/a | 36 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
US Patent
| Assay Description Formation of kynurenic acid (KYNA) is indirectly assessed by a decrease in light absorbance at 370 nm (OD370) as the L-kynurenine (KYN) substrate is ... |
US Patent US8598200 (2013)
|
More data for this Ligand-Target Pair | |
Kynurenine aminotransferase II (KAT II)
(Homo sapiens (Human)) | BDBM50386311
 (CHEMBL2049093)Show InChI InChI=1S/C9H9ClN2O2/c10-6-1-2-8-5(3-6)4-7(11)9(13)12(8)14/h1-3,7,14H,4,11H2/t7-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet 
| CHEMBL PC cid PC sid UniChem
Similars AffyNet 
| Article
| n/a | n/a | 36 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human recombinant KAT2 assessed as conversion of L-kynurenine into kynurenic acid after 15 to 20 hrs |
Citation and Details
|
More data for this Ligand-Target Pair | |
Kynurenine aminotransferase II (KAT II)
(Homo sapiens (Human)) | BDBM107724
 (US8933095, 8)Show InChI InChI=1S/C17H16N4O2/c18-15-8-13-10-20(19-16(13)21(23)17(15)22)9-12-6-3-5-11-4-1-2-7-14(11)12/h1-7,10,15,23H,8-9,18H2/t15-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet 
| PC cid PC sid UniChem
Similars AffyNet 
| US Patent
| n/a | n/a | 36 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
US Patent
| Assay Description Formation of kynurenic acid (KYNA) is indirectly assessed by a decrease in light absorbance at 370 nm (OD370) as the L-kynurenine (KYN) substrate is ... |
US Patent US8933095 (2015)
|
More data for this Ligand-Target Pair | |
Kynurenine aminotransferase II (KAT II)
(Homo sapiens (Human)) | BDBM107743
 (US8933095, 27)Show SMILES Cn1nc2N(O)C(=O)[C@@H](N)Cc2c1Cc1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C15H15F3N4O2/c1-21-12(6-8-2-4-9(5-3-8)15(16,17)18)10-7-11(19)14(23)22(24)13(10)20-21/h2-5,11,24H,6-7,19H2,1H3/t11-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet 
| PC cid PC sid UniChem
Similars AffyNet 
| US Patent
| n/a | n/a | 37 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
US Patent
| Assay Description Formation of kynurenic acid (KYNA) is indirectly assessed by a decrease in light absorbance at 370 nm (OD370) as the L-kynurenine (KYN) substrate is ... |
US Patent US8933095 (2015)
|
More data for this Ligand-Target Pair | |
Kynurenine aminotransferase II (KAT II)
(Homo sapiens (Human)) | BDBM50386309
 (CHEMBL2047862)Show InChI InChI=1S/C10H12N2O2/c1-6-2-3-7-5-8(11)10(13)12(14)9(7)4-6/h2-4,8,14H,5,11H2,1H3/t8-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet 
| Purchase
CHEMBL PC cid PC sid UniChem
Similars AffyNet 
| Article
| n/a | n/a | 37 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human recombinant KAT2 assessed as conversion of L-kynurenine into kynurenic acid after 15 to 20 hrs |
Citation and Details
|
More data for this Ligand-Target Pair | |
Kynurenine aminotransferase II (KAT II)
(Homo sapiens (Human)) | BDBM50426340
 (CHEMBL2321943)Show InChI InChI=1S/C16H16N2O4/c1-21-14-9-13-10(7-12(17)16(19)18(13)20)8-15(14)22-11-5-3-2-4-6-11/h2-6,8-9,12,20H,7,17H2,1H3/t12-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet 
| CHEMBL PC cid PC sid UniChem
Similars AffyNet 
| Article
| n/a | n/a | 37 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human KAT2 using L-kynurenine as substrate measured after 15-20 hrs by SpectraMax plate reader analysis |
Citation and Details
|
More data for this Ligand-Target Pair | |
Kynurenine aminotransferase II (KAT II)
(Homo sapiens (Human)) | BDBM107743
 (US8933095, 27)Show SMILES Cn1nc2N(O)C(=O)[C@@H](N)Cc2c1Cc1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C15H15F3N4O2/c1-21-12(6-8-2-4-9(5-3-8)15(16,17)18)10-7-11(19)14(23)22(24)13(10)20-21/h2-5,11,24H,6-7,19H2,1H3/t11-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet 
| PC cid PC sid UniChem
Similars AffyNet 
| US Patent
| n/a | n/a | 37 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
US Patent
| Assay Description Formation of kynurenic acid (KYNA) is indirectly assessed by a decrease in light absorbance at 370 nm (OD370) as the L-kynurenine (KYN) substrate is ... |
US Patent US8598200 (2013)
|
More data for this Ligand-Target Pair | |
Kynurenine aminotransferase II (KAT II)
(Homo sapiens (Human)) | BDBM50432208
 (CHEMBL2347110)Show InChI InChI=1S/C17H18N2O3/c1-22-16-10-15-12(9-14(18)17(20)19(15)21)8-13(16)7-11-5-3-2-4-6-11/h2-6,8,10,14,21H,7,9,18H2,1H3/t14-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet 
| CHEMBL PC cid PC sid UniChem
Similars AffyNet 
| Article PubMed
| n/a | n/a | 37 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description Inhibition of human KAT2 using L-kynurenine as substrate after 15 to 20 hrs by UV-visible spectra analysis |
Bioorg Med Chem Lett 23: 1961-6 (2013)
|
More data for this Ligand-Target Pair | |
Kynurenine aminotransferase II (KAT II)
(Homo sapiens (Human)) | BDBM107744
 (US8933095, 28)Show InChI InChI=1S/C13H11F3N4O2/c14-13(15,16)8-3-1-2-4-10(8)19-6-7-5-9(17)12(21)20(22)11(7)18-19/h1-4,6,9,22H,5,17H2/t9-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet 
| PC cid PC sid UniChem
Similars AffyNet 
| US Patent
| n/a | n/a | 38.8 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
US Patent
| Assay Description Formation of kynurenic acid (KYNA) is indirectly assessed by a decrease in light absorbance at 370 nm (OD370) as the L-kynurenine (KYN) substrate is ... |
US Patent US8933095 (2015)
|
More data for this Ligand-Target Pair | |
Kynurenine aminotransferase II (KAT II)
(Homo sapiens (Human)) | BDBM107744
 (US8933095, 28)Show InChI InChI=1S/C13H11F3N4O2/c14-13(15,16)8-3-1-2-4-10(8)19-6-7-5-9(17)12(21)20(22)11(7)18-19/h1-4,6,9,22H,5,17H2/t9-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet 
| PC cid PC sid UniChem
Similars AffyNet 
| US Patent
| n/a | n/a | 38.8 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
US Patent
| Assay Description Formation of kynurenic acid (KYNA) is indirectly assessed by a decrease in light absorbance at 370 nm (OD370) as the L-kynurenine (KYN) substrate is ... |
US Patent US8598200 (2013)
|
More data for this Ligand-Target Pair | |
Kynurenine aminotransferase II (KAT II)
(Homo sapiens (Human)) | BDBM50386303
 (CHEMBL2047856)Show InChI InChI=1S/C9H9FN2O2/c10-6-3-1-2-5-4-7(11)9(13)12(14)8(5)6/h1-3,7,14H,4,11H2/t7-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet 
| CHEMBL PC cid PC sid UniChem
Similars AffyNet 
| Article
| n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human recombinant KAT2 assessed as conversion of L-kynurenine into kynurenic acid after 15 to 20 hrs |
Citation and Details
|
More data for this Ligand-Target Pair | |
Kynurenine aminotransferase II (KAT II)
(Homo sapiens (Human)) | BDBM107742
 (US8933095, 26)Show SMILES Cn1nc2N(O)C(=O)[C@@H](N)Cc2c1Cc1ccccc1C(F)(F)F Show InChI InChI=1S/C15H15F3N4O2/c1-21-12(6-8-4-2-3-5-10(8)15(16,17)18)9-7-11(19)14(23)22(24)13(9)20-21/h2-5,11,24H,6-7,19H2,1H3/t11-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet 
| PC cid PC sid UniChem
Similars AffyNet 
| US Patent
| n/a | n/a | 40.7 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
US Patent
| Assay Description Formation of kynurenic acid (KYNA) is indirectly assessed by a decrease in light absorbance at 370 nm (OD370) as the L-kynurenine (KYN) substrate is ... |
US Patent US8933095 (2015)
|
More data for this Ligand-Target Pair | |
Kynurenine aminotransferase II (KAT II)
(Homo sapiens (Human)) | BDBM107742
 (US8933095, 26)Show SMILES Cn1nc2N(O)C(=O)[C@@H](N)Cc2c1Cc1ccccc1C(F)(F)F Show InChI InChI=1S/C15H15F3N4O2/c1-21-12(6-8-4-2-3-5-10(8)15(16,17)18)9-7-11(19)14(23)22(24)13(9)20-21/h2-5,11,24H,6-7,19H2,1H3/t11-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet 
| PC cid PC sid UniChem
Similars AffyNet 
| US Patent
| n/a | n/a | 40.7 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
US Patent
| Assay Description Formation of kynurenic acid (KYNA) is indirectly assessed by a decrease in light absorbance at 370 nm (OD370) as the L-kynurenine (KYN) substrate is ... |
US Patent US8598200 (2013)
|
More data for this Ligand-Target Pair | |
Kynurenine aminotransferase II (KAT II)
(Homo sapiens (Human)) | BDBM107741
 (US8933095, 25)Show SMILES Cn1nc2N(O)C(=O)[C@@H](N)Cc2c1Cc1cccc(c1)C(F)(F)F Show InChI InChI=1S/C15H15F3N4O2/c1-21-12(6-8-3-2-4-9(5-8)15(16,17)18)10-7-11(19)14(23)22(24)13(10)20-21/h2-5,11,24H,6-7,19H2,1H3/t11-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet 
| PC cid PC sid UniChem
Similars AffyNet 
| US Patent
| n/a | n/a | 42.2 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
US Patent
| Assay Description Formation of kynurenic acid (KYNA) is indirectly assessed by a decrease in light absorbance at 370 nm (OD370) as the L-kynurenine (KYN) substrate is ... |
US Patent US8598200 (2013)
|
More data for this Ligand-Target Pair | |
Kynurenine aminotransferase II (KAT II)
(Homo sapiens (Human)) | BDBM107741
 (US8933095, 25)Show SMILES Cn1nc2N(O)C(=O)[C@@H](N)Cc2c1Cc1cccc(c1)C(F)(F)F Show InChI InChI=1S/C15H15F3N4O2/c1-21-12(6-8-3-2-4-9(5-8)15(16,17)18)10-7-11(19)14(23)22(24)13(10)20-21/h2-5,11,24H,6-7,19H2,1H3/t11-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet 
| PC cid PC sid UniChem
Similars AffyNet 
| US Patent
| n/a | n/a | 42.2 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
US Patent
| Assay Description Formation of kynurenic acid (KYNA) is indirectly assessed by a decrease in light absorbance at 370 nm (OD370) as the L-kynurenine (KYN) substrate is ... |
US Patent US8933095 (2015)
|
More data for this Ligand-Target Pair | |
Kynurenine aminotransferase II (KAT II)
(Homo sapiens (Human)) | BDBM107722
 (CHEMBL2347114 | US8933095, 5)Show SMILES N[C@H]1Cc2c(N(O)C1=O)c(nn2Cc1ccccc1)C(F)(F)F Show InChI InChI=1S/C14H13F3N4O2/c15-14(16,17)12-11-10(6-9(18)13(22)21(11)23)20(19-12)7-8-4-2-1-3-5-8/h1-5,9,23H,6-7,18H2/t9-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet 
| CHEMBL PC cid PC sid UniChem
Similars AffyNet 
| US Patent
| n/a | n/a | 42.7 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
US Patent
| Assay Description Formation of kynurenic acid (KYNA) is indirectly assessed by a decrease in light absorbance at 370 nm (OD370) as the L-kynurenine (KYN) substrate is ... |
US Patent US8933095 (2015)
|
More data for this Ligand-Target Pair | |
Kynurenine aminotransferase II (KAT II)
(Homo sapiens (Human)) | BDBM107723
 (US8933095, 6)Show SMILES N[C@H]1Cc2cn(Cc3ccc(OC(F)(F)F)cc3)nc2N(O)C1=O Show InChI InChI=1S/C14H13F3N4O3/c15-14(16,17)24-10-3-1-8(2-4-10)6-20-7-9-5-11(18)13(22)21(23)12(9)19-20/h1-4,7,11,23H,5-6,18H2/t11-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet 
| PC cid PC sid UniChem
Similars AffyNet 
| US Patent
| n/a | n/a | 43.6 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
US Patent
| Assay Description Formation of kynurenic acid (KYNA) is indirectly assessed by a decrease in light absorbance at 370 nm (OD370) as the L-kynurenine (KYN) substrate is ... |
US Patent US8598200 (2013)
|
More data for this Ligand-Target Pair | |
Kynurenine aminotransferase II (KAT II)
(Homo sapiens (Human)) | BDBM107723
 (US8933095, 6)Show SMILES N[C@H]1Cc2cn(Cc3ccc(OC(F)(F)F)cc3)nc2N(O)C1=O Show InChI InChI=1S/C14H13F3N4O3/c15-14(16,17)24-10-3-1-8(2-4-10)6-20-7-9-5-11(18)13(22)21(23)12(9)19-20/h1-4,7,11,23H,5-6,18H2/t11-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet 
| PC cid PC sid UniChem
Similars AffyNet 
| US Patent
| n/a | n/a | 43.6 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
US Patent
| Assay Description Formation of kynurenic acid (KYNA) is indirectly assessed by a decrease in light absorbance at 370 nm (OD370) as the L-kynurenine (KYN) substrate is ... |
US Patent US8933095 (2015)
|
More data for this Ligand-Target Pair | |
Kynurenine aminotransferase II (KAT II)
(Homo sapiens (Human)) | BDBM107722
 (CHEMBL2347114 | US8933095, 5)Show SMILES N[C@H]1Cc2c(N(O)C1=O)c(nn2Cc1ccccc1)C(F)(F)F Show InChI InChI=1S/C14H13F3N4O2/c15-14(16,17)12-11-10(6-9(18)13(22)21(11)23)20(19-12)7-8-4-2-1-3-5-8/h1-5,9,23H,6-7,18H2/t9-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet 
| CHEMBL PC cid PC sid UniChem
Similars AffyNet 
| US Patent
| n/a | n/a | 43.7 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
US Patent
| Assay Description Formation of kynurenic acid (KYNA) is indirectly assessed by a decrease in light absorbance at 370 nm (OD370) as the L-kynurenine (KYN) substrate is ... |
US Patent US8598200 (2013)
|
More data for this Ligand-Target Pair | |
Kynurenine aminotransferase II (KAT II)
(Homo sapiens (Human)) | BDBM50386295
 (CHEMBL2049096)Show InChI InChI=1S/C9H9FN2O2/c10-6-2-1-3-8-5(6)4-7(11)9(13)12(8)14/h1-3,7,14H,4,11H2/t7-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet 
| CHEMBL PC cid PC sid UniChem AffyNet 
| Article
| n/a | n/a | 45 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human recombinant KAT2 assessed as conversion of L-kynurenine into kynurenic acid after 15 to 20 hrs |
Citation and Details
|
More data for this Ligand-Target Pair | |
Kynurenine aminotransferase II (KAT II)
(Homo sapiens (Human)) | BDBM107746
 (CHEMBL2347107 | US8933095, 1)Show InChI InChI=1S/C13H14N4O2/c14-11-6-10-8-16(7-9-4-2-1-3-5-9)15-12(10)17(19)13(11)18/h1-5,8,11,19H,6-7,14H2/t11-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet 
| CHEMBL PC cid PC sid UniChem
Similars AffyNet 
| Article PubMed
| n/a | n/a | 47 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description Inhibition of human KAT2 using L-kynurenine as substrate after 15 to 20 hrs by UV-visible spectra analysis |
Bioorg Med Chem Lett 23: 1961-6 (2013)
|
More data for this Ligand-Target Pair | |
Kynurenine aminotransferase II (KAT II)
(Homo sapiens (Human)) | BDBM107726
 (US8933095, 10)Show InChI InChI=1S/C14H16N4O3/c1-21-12-5-3-2-4-9(12)7-17-8-10-6-11(15)14(19)18(20)13(10)16-17/h2-5,8,11,20H,6-7,15H2,1H3/t11-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet 
| PC cid PC sid UniChem
Similars AffyNet 
| US Patent
| n/a | n/a | 50.2 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
US Patent
| Assay Description Formation of kynurenic acid (KYNA) is indirectly assessed by a decrease in light absorbance at 370 nm (OD370) as the L-kynurenine (KYN) substrate is ... |
US Patent US8598200 (2013)
|
More data for this Ligand-Target Pair | |
Kynurenine aminotransferase II (KAT II)
(Homo sapiens (Human)) | BDBM107726
 (US8933095, 10)Show InChI InChI=1S/C14H16N4O3/c1-21-12-5-3-2-4-9(12)7-17-8-10-6-11(15)14(19)18(20)13(10)16-17/h2-5,8,11,20H,6-7,15H2,1H3/t11-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet 
| PC cid PC sid UniChem
Similars AffyNet 
| US Patent
| n/a | n/a | 50.2 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
US Patent
| Assay Description Formation of kynurenic acid (KYNA) is indirectly assessed by a decrease in light absorbance at 370 nm (OD370) as the L-kynurenine (KYN) substrate is ... |
US Patent US8933095 (2015)
|
More data for this Ligand-Target Pair | |
Kynurenine aminotransferase II (KAT II)
(Homo sapiens (Human)) | BDBM107746
 (CHEMBL2347107 | US8933095, 1)Show InChI InChI=1S/C13H14N4O2/c14-11-6-10-8-16(7-9-4-2-1-3-5-9)15-12(10)17(19)13(11)18/h1-5,8,11,19H,6-7,14H2/t11-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet 
| CHEMBL PC cid PC sid UniChem
Similars AffyNet 
| US Patent
| n/a | n/a | 59.4 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
US Patent
| Assay Description Formation of kynurenic acid (KYNA) is indirectly assessed by a decrease in light absorbance at 370 nm (OD370) as the L-kynurenine (KYN) substrate is ... |
US Patent US8598200 (2013)
|
More data for this Ligand-Target Pair | |
Kynurenine aminotransferase II (KAT II)
(Homo sapiens (Human)) | BDBM107746
 (CHEMBL2347107 | US8933095, 1)Show InChI InChI=1S/C13H14N4O2/c14-11-6-10-8-16(7-9-4-2-1-3-5-9)15-12(10)17(19)13(11)18/h1-5,8,11,19H,6-7,14H2/t11-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet 
| CHEMBL PC cid PC sid UniChem
Similars AffyNet 
| US Patent
| n/a | n/a | 59.4 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
US Patent
| Assay Description Formation of kynurenic acid (KYNA) is indirectly assessed by a decrease in light absorbance at 370 nm (OD370) as the L-kynurenine (KYN) substrate is ... |
US Patent US8933095 (2015)
|
More data for this Ligand-Target Pair | |
Kynurenine aminotransferase II (KAT II)
(Homo sapiens (Human)) | BDBM107740
 (US8933095, 24)Show InChI InChI=1S/C16H20N4O2/c1-10(2)19-14(8-11-6-4-3-5-7-11)12-9-13(17)16(21)20(22)15(12)18-19/h3-7,10,13,22H,8-9,17H2,1-2H3/t13-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet 
| PC cid PC sid UniChem
Similars AffyNet 
| US Patent
| n/a | n/a | 63 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
US Patent
| Assay Description Formation of kynurenic acid (KYNA) is indirectly assessed by a decrease in light absorbance at 370 nm (OD370) as the L-kynurenine (KYN) substrate is ... |
US Patent US8598200 (2013)
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More data for this Ligand-Target Pair | |