Compile Data Set for Download or QSAR

Found 181 hits of ec50 data for polymerid = 5868   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50060964 ((R)-5-(2-((2-(2-ethoxyphenoxy)ethyl)amino)propyl)-...) Show SMILES CCOc1ccccc1OCCN[C@H](C)Cc1ccc(OC)c(c1)S(N)(=O)=O Show InChI InChI=1S/C20H28N2O5S/c1-4-26-17-7-5-6-8-18(17)27-12-11-22-15(2)13-16-9-10-19(25-3)20(14-16)28(21,23)24/h5-10,14-15,22H,4,11-13H2,1-3H3,(H2,21,23,24)/t15-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents Similars		n/a	n/a	n/a	n/a	0.0700	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50000210 (CHEMBL422477) Show SMILES C(Oc1ccccc1-c1ccsc1)C1=NCCN1 Show InChI InChI=1S/C14H14N2OS/c1-2-4-13(17-9-14-15-6-7-16-14)12(3-1)11-5-8-18-10-11/h1-5,8,10H,6-7,9H2,(H,15,16)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	0.25	n/a	n/a	n/a	n/a
GlaxoSmithKline Research and Development Curated by ChEMBL					Assay Description Activation of recombinant human adrenergic,alpha-1A receptor expressed in rat-1 fibroblasts determined via calcium mobilization through Gq coupled PL...				Citation and Details Checked by Author
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50258559 ((S)-6-(2-(pyrimidin-5-yl)phenyl)-6,7-dihydro-5H-py...) Show SMILES C1[C@H](Cn2ccnc12)c1ccccc1-c1cncnc1 Show InChI InChI=1S/C16H14N4/c1-2-4-15(13-8-17-11-18-9-13)14(3-1)12-7-16-19-5-6-20(16)10-12/h1-6,8-9,11-12H,7,10H2/t12-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.400	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human adrenergic alpha1A receptor expressed in CHO cells assessed as calcium mobilization by FLIPR				Bioorg Med Chem Lett 19: 3113-7 (2009)
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50000195 (CHEMBL142784) Show SMILES C(Oc1ccccc1-c1ccoc1)C1=NCCN1 Show InChI InChI=1S/C14H14N2O2/c1-2-4-13(18-10-14-15-6-7-16-14)12(3-1)11-5-8-17-9-11/h1-5,8-9H,6-7,10H2,(H,15,16)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	n/a	n/a	0.5	n/a	n/a	n/a	n/a
GlaxoSmithKline Research and Development Curated by ChEMBL					Assay Description Activation of recombinant human adrenergic,alpha-1A receptor expressed in rat-1 fibroblasts determined via calcium mobilization through Gq coupled PL...				Citation and Details Checked by Author
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50258594 (6-(5-fluoro-2-(pyrimidin-5-yl)phenyl)-6,7-dihydro-...) Show SMILES Fc1ccc(-c2cncnc2)c(c1)C1Cc2nccn2C1 Show InChI InChI=1S/C16H13FN4/c17-13-1-2-14(12-7-18-10-19-8-12)15(6-13)11-5-16-20-3-4-21(16)9-11/h1-4,6-8,10-11H,5,9H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human adrenergic alpha1A receptor expressed in CHO cells assessed as calcium mobilization by FLIPR				Bioorg Med Chem Lett 19: 3113-7 (2009)
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50000216 (CHEMBL143801) Show SMILES C(Oc1ccccc1-c1cccs1)C1=NCCN1 Show InChI InChI=1S/C14H14N2OS/c1-2-5-12(17-10-14-15-7-8-16-14)11(4-1)13-6-3-9-18-13/h1-6,9H,7-8,10H2,(H,15,16)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	1	n/a	n/a	n/a	n/a
GlaxoSmithKline Research and Development Curated by ChEMBL					Assay Description Activation of recombinant human adrenergic,alpha-1A receptor expressed in rat-1 fibroblasts determined via calcium mobilization through Gq coupled PL...				Citation and Details Checked by Author
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50258563 ((S)-6-(2-(pyridin-3-yl)phenyl)-6,7-dihydro-5H-pyrr...) Show SMILES C1[C@H](Cn2ccnc12)c1ccccc1-c1cccnc1 Show InChI InChI=1S/C17H15N3/c1-2-6-16(14-10-17-19-8-9-20(17)12-14)15(5-1)13-4-3-7-18-11-13/h1-9,11,14H,10,12H2/t14-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human adrenergic alpha1A receptor expressed in CHO cells assessed as calcium mobilization by FLIPR				Bioorg Med Chem Lett 19: 3113-7 (2009)
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50421593 (CHEMBL357129) Show SMILES C(Oc1ccccc1-c1ccc[nH]1)C1=NCCN1 Show InChI InChI=1S/C14H15N3O/c1-2-6-13(18-10-14-16-8-9-17-14)11(4-1)12-5-3-7-15-12/h1-7,15H,8-10H2,(H,16,17)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	1.30	n/a	n/a	n/a	n/a
GlaxoSmithKline Research and Development Curated by ChEMBL					Assay Description Activation of recombinant human adrenergic,alpha-1A receptor expressed in rat-1 fibroblasts determined via calcium mobilization through Gq coupled PL...				Citation and Details Checked by Author
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50000197 (CHEMBL279136) Show SMILES C(Oc1ccccc1-c1ccco1)C1=NCCN1 Show InChI InChI=1S/C14H14N2O2/c1-2-5-13(18-10-14-15-7-8-16-14)11(4-1)12-6-3-9-17-12/h1-6,9H,7-8,10H2,(H,15,16)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	1.30	n/a	n/a	n/a	n/a
GlaxoSmithKline Research and Development Curated by ChEMBL					Assay Description Activation of recombinant human adrenergic,alpha-1A receptor expressed in rat-1 fibroblasts determined via calcium mobilization through Gq coupled PL...				Citation and Details Checked by Author
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50421594 (CHEMBL356605) Show SMILES C(Oc1ccccc1-c1cccnc1)C1=NCCN1 Show InChI InChI=1S/C15H15N3O/c1-2-6-14(19-11-15-17-8-9-18-15)13(5-1)12-4-3-7-16-10-12/h1-7,10H,8-9,11H2,(H,17,18)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	2	n/a	n/a	n/a	n/a
GlaxoSmithKline Research and Development Curated by ChEMBL					Assay Description Activation of recombinant human adrenergic,alpha-1A receptor expressed in rat-1 fibroblasts determined via calcium mobilization through Gq coupled PL...				Citation and Details Checked by Author
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50258560 ((S)-2-(2-(6,7-dihydro-5H-pyrrolo[1,2-a]imidazol-6-...) Show SMILES C1[C@H](Cn2ccnc12)c1ccccc1-c1ncco1 Show InChI InChI=1S/C15H13N3O/c1-2-4-13(15-17-6-8-19-15)12(3-1)11-9-14-16-5-7-18(14)10-11/h1-8,11H,9-10H2/t11-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human adrenergic alpha1A receptor expressed in CHO cells assessed as calcium mobilization by FLIPR				Bioorg Med Chem Lett 19: 3113-7 (2009)
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50000208 (CHEMBL142871) Show SMILES C(Oc1ccccc1-c1nccs1)C1=NCCN1 Show InChI InChI=1S/C13H13N3OS/c1-2-4-11(17-9-12-14-5-6-15-12)10(3-1)13-16-7-8-18-13/h1-4,7-8H,5-6,9H2,(H,14,15)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	2.5	n/a	n/a	n/a	n/a
GlaxoSmithKline Research and Development Curated by ChEMBL					Assay Description Activation of recombinant human adrenergic,alpha-1A receptor expressed in rat-1 fibroblasts determined via calcium mobilization through Gq coupled PL...				Citation and Details Checked by Author
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50000218 (CHEMBL143973) Show SMILES C(Oc1ccccc1-c1cnccn1)C1=NCCN1 Show InChI InChI=1S/C14H14N4O/c1-2-4-13(19-10-14-17-7-8-18-14)11(3-1)12-9-15-5-6-16-12/h1-6,9H,7-8,10H2,(H,17,18)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	2.5	n/a	n/a	n/a	n/a
GlaxoSmithKline Research and Development Curated by ChEMBL					Assay Description Activation of recombinant human adrenergic,alpha-1A receptor expressed in rat-1 fibroblasts determined via calcium mobilization through Gq coupled PL...				Citation and Details Checked by Author
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50377387 (CHEMBL260720) Show SMILES Cc1[nH]ncc1-c1cccc2C(CCc12)c1ncc[nH]1 Show InChI InChI=1S/C16H16N4/c1-10-15(9-19-20-10)12-4-2-3-11-13(12)5-6-14(11)16-17-7-8-18-16/h2-4,7-9,14H,5-6H2,1H3,(H,17,18)(H,19,20)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Agonist activity at human cloned adrenergic alpha-1A receptor expressed in CHO cells assessed as calcium mobilization by FLIPR				Bioorg Med Chem Lett 18: 2930-4 (2008)
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50258642 (6-(5-fluoro-2-(1H-pyrazol-5-yl)phenyl)-6,7-dihydro...) Show SMILES Fc1ccc(-c2cc[nH]n2)c(c1)C1Cc2nccn2C1 Show InChI InChI=1S/C15H13FN4/c16-11-1-2-12(14-3-4-18-19-14)13(8-11)10-7-15-17-5-6-20(15)9-10/h1-6,8,10H,7,9H2,(H,18,19)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human adrenergic alpha1A receptor expressed in CHO cells assessed as calcium mobilization by FLIPR				Bioorg Med Chem Lett 19: 3113-7 (2009)
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50258562 ((S)-2-(2-(6,7-dihydro-5H-pyrrolo[1,2-a]imidazol-6-...) Show SMILES C1[C@H](Cn2ccnc12)c1ccccc1-c1nccs1 Show InChI InChI=1S/C15H13N3S/c1-2-4-13(15-17-6-8-19-15)12(3-1)11-9-14-16-5-7-18(14)10-11/h1-8,11H,9-10H2/t11-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	3	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human adrenergic alpha1A receptor expressed in CHO cells assessed as calcium mobilization by FLIPR				Bioorg Med Chem Lett 19: 3113-7 (2009)
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50258640 (2-(2-(6,7-dihydro-5H-pyrrolo[1,2-a]imidazol-6-yl)-...) Show SMILES Fc1ccc(-c2ncco2)c(c1)C1Cc2nccn2C1 Show InChI InChI=1S/C15H12FN3O/c16-11-1-2-12(15-18-4-6-20-15)13(8-11)10-7-14-17-3-5-19(14)9-10/h1-6,8,10H,7,9H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human adrenergic alpha1A receptor expressed in CHO cells assessed as calcium mobilization by FLIPR				Bioorg Med Chem Lett 19: 3113-7 (2009)
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50421578 (CHEMBL13789) Show SMILES C(Oc1ccccc1-c1ccccc1)C1=NCCN1 Show InChI InChI=1S/C16H16N2O/c1-2-6-13(7-3-1)14-8-4-5-9-15(14)19-12-16-17-10-11-18-16/h1-9H,10-12H2,(H,17,18)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	3.20	n/a	n/a	n/a	n/a
GlaxoSmithKline Research and Development Curated by ChEMBL					Assay Description Activation of recombinant human adrenergic,alpha-1A receptor expressed in rat-1 fibroblasts determined via calcium mobilization through Gq coupled PL...				Citation and Details Checked by Author
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50421595 (CHEMBL143562) Show SMILES Cc1ccoc1-c1ccccc1OCC1=NCCN1 Show InChI InChI=1S/C15H16N2O2/c1-11-6-9-18-15(11)12-4-2-3-5-13(12)19-10-14-16-7-8-17-14/h2-6,9H,7-8,10H2,1H3,(H,16,17)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	3.20	n/a	n/a	n/a	n/a
GlaxoSmithKline Research and Development Curated by ChEMBL					Assay Description Activation of recombinant human adrenergic,alpha-1A receptor expressed in rat-1 fibroblasts determined via calcium mobilization through Gq coupled PL...				Citation and Details Checked by Author
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50258590 ((S)-N-(2'-(6,7-dihydro-5H-pyrrolo[1,2-a]imidazol-6...) Show SMILES CS(=O)(=O)Nc1cccc(c1)-c1ccccc1[C@@H]1Cc2nccn2C1 Show InChI InChI=1S/C19H19N3O2S/c1-25(23,24)21-16-6-4-5-14(11-16)17-7-2-3-8-18(17)15-12-19-20-9-10-22(19)13-15/h2-11,15,21H,12-13H2,1H3/t15-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	4	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human adrenergic alpha1A receptor expressed in CHO cells assessed as calcium mobilization by FLIPR				Bioorg Med Chem Lett 19: 3113-7 (2009)
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50000205 (CHEMBL344551) Show SMILES C(Oc1ccccc1-c1cc[nH]n1)C1=NCCN1 Show InChI InChI=1S/C13H14N4O/c1-2-4-12(18-9-13-14-7-8-15-13)10(3-1)11-5-6-16-17-11/h1-6H,7-9H2,(H,14,15)(H,16,17)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	5	n/a	n/a	n/a	n/a
GlaxoSmithKline Research and Development Curated by ChEMBL					Assay Description Activation of recombinant human adrenergic,alpha-1A receptor expressed in rat-1 fibroblasts determined via calcium mobilization through Gq coupled PL...				Citation and Details Checked by Author
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50000207 (CHEMBL142387) Show SMILES C(Oc1ccccc1-c1ccns1)C1=NCCN1 Show InChI InChI=1S/C13H13N3OS/c1-2-4-11(17-9-13-14-7-8-15-13)10(3-1)12-5-6-16-18-12/h1-6H,7-9H2,(H,14,15)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	5	n/a	n/a	n/a	n/a
GlaxoSmithKline Research and Development Curated by ChEMBL					Assay Description Activation of recombinant human adrenergic,alpha-1A receptor expressed in rat-1 fibroblasts determined via calcium mobilization through Gq coupled PL...				Citation and Details Checked by Author
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50258589 ((S)-6-(2-(1H-pyrazol-1-yl)phenyl)-6,7-dihydro-5H-p...) Show SMILES C1[C@H](Cn2ccnc12)c1ccccc1-n1cccn1 Show InChI InChI=1S/C15H14N4/c1-2-5-14(19-8-3-6-17-19)13(4-1)12-10-15-16-7-9-18(15)11-12/h1-9,12H,10-11H2/t12-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	5	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human adrenergic alpha1A receptor expressed in CHO cells assessed as calcium mobilization by FLIPR				Bioorg Med Chem Lett 19: 3113-7 (2009)
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50258643 (6-(5-fluoro-2-(1H-pyrazol-1-yl)phenyl)-6,7-dihydro...) Show SMILES Fc1ccc(c(c1)C1Cc2nccn2C1)-n1cccn1 Show InChI InChI=1S/C15H13FN4/c16-12-2-3-14(20-6-1-4-18-20)13(9-12)11-8-15-17-5-7-19(15)10-11/h1-7,9,11H,8,10H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	5	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human adrenergic alpha1A receptor expressed in CHO cells assessed as calcium mobilization by FLIPR				Bioorg Med Chem Lett 19: 3113-7 (2009)
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50000214 (CHEMBL337862) Show SMILES C(Nc1ccccc1-c1ccccc1)C1=NCCN1 Show InChI InChI=1S/C16H17N3/c1-2-6-13(7-3-1)14-8-4-5-9-15(14)19-12-16-17-10-11-18-16/h1-9,19H,10-12H2,(H,17,18)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	7.90	n/a	n/a	n/a	n/a
GlaxoSmithKline Research and Development Curated by ChEMBL					Assay Description Activation of recombinant human adrenergic,alpha-1A receptor expressed in rat-1 fibroblasts determined via calcium mobilization through Gq coupled PL...				Citation and Details Checked by Author
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50258565 ((S)-6-(2-(1-methyl-1H-pyrazol-4-yl)phenyl)-6,7-dih...) Show SMILES Cn1cc(cn1)-c1ccccc1[C@@H]1Cc2nccn2C1 Show InChI InChI=1S/C16H16N4/c1-19-10-13(9-18-19)15-5-3-2-4-14(15)12-8-16-17-6-7-20(16)11-12/h2-7,9-10,12H,8,11H2,1H3/t12-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	9	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human adrenergic alpha1A receptor expressed in CHO cells assessed as calcium mobilization by FLIPR				Bioorg Med Chem Lett 19: 3113-7 (2009)
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50256615 ((R)-3-fluoro-1-((5-fluoro-1-(1H-imidazol-2-yl)-2,3...) Show SMILES Fc1ccn(Cc2c3CC[C@@H](c4ncc[nH]4)c3ccc2F)n1 Show InChI InChI=1S/C16H14F2N4/c17-14-4-3-10-11(1-2-12(10)16-19-6-7-20-16)13(14)9-22-8-5-15(18)21-22/h3-8,12H,1-2,9H2,(H,19,20)/t12-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	9	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human cloned adrenergic alpha1A receptor expressed in CHO cells by calcium mobilization-based fluorescence assay				Bioorg Med Chem Lett 18: 6437-40 (2008)
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50118705 (ABT-866 | CHEMBL326702 | Ethanesulfonic acid [3-(1...) Show SMILES CCS(=O)(=O)Nc1cccc(Cc2cnc[nH]2)c1 Show InChI InChI=1S/C12H15N3O2S/c1-2-18(16,17)15-11-5-3-4-10(6-11)7-12-8-13-9-14-12/h3-6,8-9,15H,2,7H2,1H3,(H,13,14)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	9	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Agonist activity at human cloned adrenergic alpha-1A receptor expressed in CHO cells assessed as calcium mobilization by FLIPR				Bioorg Med Chem Lett 18: 2930-4 (2008)
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50029051 ((-)-arterenol | (-)-noradrenaline | (-)-norepineph...) Show SMILES NC[C@H](O)c1ccc(O)c(O)c1 Show InChI InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2/t8-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	9.10	n/a	n/a	n/a	n/a
Asahi Kasei Pharma Corporation Curated by ChEMBL					Assay Description Agonist activity at human alpha1A-adrenergic receptor expressed in HEK293 cells assessed as calcium flux by fluorescence assay				Citation and Details
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50118703 (CHEMBL109783 | N-[5-(4,5-Dihydro-1H-imidazol-2-yl)...) Show SMILES CS(=O)(=O)Nc1c(O)ccc2C(CCCc12)C1=NCCN1 Show InChI InChI=1S/C14H19N3O3S/c1-21(19,20)17-13-10-3-2-4-11(14-15-7-8-16-14)9(10)5-6-12(13)18/h5-6,11,17-18H,2-4,7-8H2,1H3,(H,15,16)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	n/a	n/a	9.30	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Effective concentration of the compound was determined in vitro against rabbit urethra Alpha-1 adrenergic receptor				Citation and Details
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50198640 (CHEMBL3947830) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars		n/a	n/a	n/a	n/a	11	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50259535 (6-(2-(difluoromethoxy)phenyl)-6,7-dihydro-5H-pyrro...) Show SMILES FC(F)Oc1ccccc1C1Cc2nccn2C1 Show InChI InChI=1S/C13H12F2N2O/c14-13(15)18-11-4-2-1-3-10(11)9-7-12-16-5-6-17(12)8-9/h1-6,9,13H,7-8H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	11	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human cloned adrenergic alpha1A receptor expressed in CHO cells assessed as calcium mobilization by FLIPR				Bioorg Med Chem Lett 19: 3118-21 (2009)
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50258591 ((S)-2-(2-(6,7-dihydro-5H-pyrrolo[1,2-a]imidazol-6-...) Show SMILES CNS(=O)(=O)CCc1ccccc1[C@@H]1Cc2nccn2C1 Show InChI InChI=1S/C15H19N3O2S/c1-16-21(19,20)9-6-12-4-2-3-5-14(12)13-10-15-17-7-8-18(15)11-13/h2-5,7-8,13,16H,6,9-11H2,1H3/t13-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	12	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human adrenergic alpha1A receptor expressed in CHO cells assessed as calcium mobilization by FLIPR				Bioorg Med Chem Lett 19: 3113-7 (2009)
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50258518 ((S)-6-(biphenyl-2-yl)-6,7-dihydro-5H-pyrrolo[1,2-a...) Show SMILES C1[C@H](Cn2ccnc12)c1ccccc1-c1ccccc1 Show InChI InChI=1S/C18H16N2/c1-2-6-14(7-3-1)16-8-4-5-9-17(16)15-12-18-19-10-11-20(18)13-15/h1-11,15H,12-13H2/t15-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	12	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human adrenergic alpha1A receptor expressed in CHO cells assessed as calcium mobilization by FLIPR				Bioorg Med Chem Lett 19: 3113-7 (2009)
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50027060 (2-(2-Cyclopropyl-phenoxymethyl)-4,5-dihydro-1H-imi...) Show SMILES C(Oc1ccccc1C1CC1)C1=NCCN1 Show InChI InChI=1S/C13H16N2O/c1-2-4-12(11(3-1)10-5-6-10)16-9-13-14-7-8-15-13/h1-4,10H,5-9H2,(H,14,15)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	13	n/a	n/a	n/a	n/a
GlaxoSmithKline Research and Development Curated by ChEMBL					Assay Description Activation of recombinant human adrenergic,alpha-1A receptor expressed in rat-1 fibroblasts determined via calcium mobilization through Gq coupled PL...				Citation and Details Checked by Author
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50421592 (CHEMBL420683) Show SMILES C(Oc1ccccc1-c1ccccn1)C1=NCCN1 Show InChI InChI=1S/C15H15N3O/c1-2-7-14(19-11-15-17-9-10-18-15)12(5-1)13-6-3-4-8-16-13/h1-8H,9-11H2,(H,17,18)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	13	n/a	n/a	n/a	n/a
GlaxoSmithKline Research and Development Curated by ChEMBL					Assay Description Activation of recombinant human adrenergic,alpha-1A receptor expressed in rat-1 fibroblasts determined via calcium mobilization through Gq coupled PL...				Citation and Details Checked by Author
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50000213 (CHEMBL341747) Show SMILES Cc1cnsc1-c1ccccc1OCC1=NCCN1 Show InChI InChI=1S/C14H15N3OS/c1-10-8-17-19-14(10)11-4-2-3-5-12(11)18-9-13-15-6-7-16-13/h2-5,8H,6-7,9H2,1H3,(H,15,16)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	13	n/a	n/a	n/a	n/a
GlaxoSmithKline Research and Development Curated by ChEMBL					Assay Description Activation of recombinant human adrenergic,alpha-1A receptor expressed in rat-1 fibroblasts determined via calcium mobilization through Gq coupled PL...				Citation and Details Checked by Author
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50377388 (CHEMBL406316) Show SMILES C1Cc2c(cccc2-c2cn[nH]c2)C1c1ncc[nH]1 Show InChI InChI=1S/C15H14N4/c1-2-11(10-8-18-19-9-10)13-4-5-14(12(13)3-1)15-16-6-7-17-15/h1-3,6-9,14H,4-5H2,(H,16,17)(H,18,19)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	14	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Agonist activity at human cloned adrenergic alpha-1A receptor expressed in CHO cells assessed as calcium mobilization by FLIPR				Bioorg Med Chem Lett 18: 2930-4 (2008)
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50258641 (6-(4-fluoro-2-(1H-pyrazol-5-yl)phenyl)-6,7-dihydro...) Show SMILES Fc1ccc(C2Cc3nccn3C2)c(c1)-c1cc[nH]n1 Show InChI InChI=1S/C15H13FN4/c16-11-1-2-12(13(8-11)14-3-4-18-19-14)10-7-15-17-5-6-20(15)9-10/h1-6,8,10H,7,9H2,(H,18,19)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	15	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human adrenergic alpha1A receptor expressed in CHO cells assessed as calcium mobilization by FLIPR				Bioorg Med Chem Lett 19: 3113-7 (2009)
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50256614 (3-fluoro-1-((2,3-dihydro-1-(1H-imidazol-2-yl)-1H-i...) Show SMILES Fc1ccn(Cc2cccc3C(CCc23)c2ncc[nH]2)n1 Show InChI InChI=1S/C16H15FN4/c17-15-6-9-21(20-15)10-11-2-1-3-13-12(11)4-5-14(13)16-18-7-8-19-16/h1-3,6-9,14H,4-5,10H2,(H,18,19)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	17	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human cloned adrenergic alpha1A receptor expressed in CHO cells by calcium mobilization-based fluorescence assay				Bioorg Med Chem Lett 18: 6437-40 (2008)
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50258593 (6-(4-fluoro-2-(pyrimidin-5-yl)phenyl)-6,7-dihydro-...) Show SMILES Fc1ccc(C2Cc3nccn3C2)c(c1)-c1cncnc1 Show InChI InChI=1S/C16H13FN4/c17-13-1-2-14(11-5-16-20-3-4-21(16)9-11)15(6-13)12-7-18-10-19-8-12/h1-4,6-8,10-11H,5,9H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	19	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human adrenergic alpha1A receptor expressed in CHO cells assessed as calcium mobilization by FLIPR				Bioorg Med Chem Lett 19: 3113-7 (2009)
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50258592 ((S)-2'-(6,7-dihydro-5H-pyrrolo[1,2-a]imidazol-6-yl...) Show SMILES CNC(=O)c1cccc(c1)-c1ccccc1[C@@H]1Cc2nccn2C1 Show InChI InChI=1S/C20H19N3O/c1-21-20(24)15-6-4-5-14(11-15)17-7-2-3-8-18(17)16-12-19-22-9-10-23(19)13-16/h2-11,16H,12-13H2,1H3,(H,21,24)/t16-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	19	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human adrenergic alpha1A receptor expressed in CHO cells assessed as calcium mobilization by FLIPR				Bioorg Med Chem Lett 19: 3113-7 (2009)
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50259486 (6-(2-chlorophenyl)-6,7-dihydro-5H-pyrrolo[1,2-a]im...) Show SMILES Clc1ccccc1C1Cc2nccn2C1 Show InChI InChI=1S/C12H11ClN2/c13-11-4-2-1-3-10(11)9-7-12-14-5-6-15(12)8-9/h1-6,9H,7-8H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	19	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human cloned adrenergic alpha1A receptor expressed in CHO cells assessed as calcium mobilization by FLIPR				Bioorg Med Chem Lett 19: 3118-21 (2009)
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50259488 (6-(2-methoxyphenyl)-6,7-dihydro-5H-pyrrolo[1,2-a]i...) Show SMILES COc1ccccc1C1Cc2nccn2C1 Show InChI InChI=1S/C13H14N2O/c1-16-12-5-3-2-4-11(12)10-8-13-14-6-7-15(13)9-10/h2-7,10H,8-9H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	22	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human cloned adrenergic alpha1A receptor expressed in CHO cells assessed as calcium mobilization by FLIPR				Bioorg Med Chem Lett 19: 3118-21 (2009)
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50020819 (CHEMBL543126 | N-[2-Hydroxy-5-(2-methylamino-ethyl...) Show SMILES CNCCc1ccc(O)c(NS(C)(=O)=O)c1 Show InChI InChI=1S/C10H16N2O3S/c1-11-6-5-8-3-4-10(13)9(7-8)12-16(2,14)15/h3-4,7,11-13H,5-6H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	25	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Effective concentration (EC50) against alpha-1-adrenoreceptor in the isolated rabbit ear artery				Citation and Details
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50377398 (CHEMBL257978 | Ro-115-1240) Show SMILES Cc1c(OCC2=NCCN2)ccc(Cl)c1NS(C)(=O)=O Show InChI InChI=1S/C12H16ClN3O3S/c1-8-10(19-7-11-14-5-6-15-11)4-3-9(13)12(8)16-20(2,17)18/h3-4,16H,5-7H2,1-2H3,(H,14,15)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	25	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Agonist activity at human cloned adrenergic alpha-1A receptor expressed in CHO cells assessed as calcium mobilization by FLIPR				Bioorg Med Chem Lett 18: 2930-4 (2008)
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50000202 (CHEMBL142958) Show SMILES Cc1ccc(s1)-c1ccccc1OCC1=NCCN1 Show InChI InChI=1S/C15H16N2OS/c1-11-6-7-14(19-11)12-4-2-3-5-13(12)18-10-15-16-8-9-17-15/h2-7H,8-10H2,1H3,(H,16,17)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	25	n/a	n/a	n/a	n/a
GlaxoSmithKline Research and Development Curated by ChEMBL					Assay Description Activation of recombinant human adrenergic,alpha-1A receptor expressed in rat-1 fibroblasts determined via calcium mobilization through Gq coupled PL...				Citation and Details Checked by Author
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50000204 (CHEMBL344957) Show SMILES Cc1csc(n1)-c1ccccc1OCC1=NCCN1 Show InChI InChI=1S/C14H15N3OS/c1-10-9-19-14(17-10)11-4-2-3-5-12(11)18-8-13-15-6-7-16-13/h2-5,9H,6-8H2,1H3,(H,15,16)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	25	n/a	n/a	n/a	n/a
GlaxoSmithKline Research and Development Curated by ChEMBL					Assay Description Activation of recombinant human adrenergic,alpha-1A receptor expressed in rat-1 fibroblasts determined via calcium mobilization through Gq coupled PL...				Citation and Details Checked by Author
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50256563 ((R)-2-(5-chloro-4-(methoxymethyl)-2,3-dihydro-1H-i...) Show SMILES COCc1c2CC[C@@H](c3ncc[nH]3)c2ccc1Cl Show InChI InChI=1S/C14H15ClN2O/c1-18-8-12-10-2-3-11(14-16-6-7-17-14)9(10)4-5-13(12)15/h4-7,11H,2-3,8H2,1H3,(H,16,17)/t11-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	27	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human cloned adrenergic alpha1A receptor expressed in CHO cells assessed as calcium mobilization by FLIPR				Bioorg Med Chem Lett 19: 3118-21 (2009)
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50258644 (6-(4-fluoro-2-(1H-pyrazol-1-yl)phenyl)-6,7-dihydro...) Show SMILES Fc1ccc(C2Cc3nccn3C2)c(c1)-n1cccn1 Show InChI InChI=1S/C15H13FN4/c16-12-2-3-13(14(9-12)20-6-1-4-18-20)11-8-15-17-5-7-19(15)10-11/h1-7,9,11H,8,10H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	27	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human adrenergic alpha1A receptor expressed in CHO cells assessed as calcium mobilization by FLIPR				Bioorg Med Chem Lett 19: 3113-7 (2009)
					More data for this Ligand-Target Pair

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