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Found 563 of ic50 data for polymerid = 5978
TargetAndrogen receptor(Rattus norvegicus (Rat))
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US Patent
LigandPNGBDBM112830(US8629167, 41)
Affinity DataIC50:  0.0200nMAssay Description:In order to demonstrate the utility of the compounds of this invention, an androgen receptor binding assay was performed wherein many of the compound...More data for this Ligand-Target Pair
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US Patent
LigandPNGBDBM112818(US8629167, 29)
Affinity DataIC50:  0.0300nMAssay Description:In order to demonstrate the utility of the compounds of this invention, an androgen receptor binding assay was performed wherein many of the compound...More data for this Ligand-Target Pair
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US Patent
LigandPNGBDBM112828(US8629167, 39)
Affinity DataIC50:  0.100nMAssay Description:In order to demonstrate the utility of the compounds of this invention, an androgen receptor binding assay was performed wherein many of the compound...More data for this Ligand-Target Pair
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US Patent
LigandPNGBDBM112829(US8629167, 40)
Affinity DataIC50:  0.200nMAssay Description:In order to demonstrate the utility of the compounds of this invention, an androgen receptor binding assay was performed wherein many of the compound...More data for this Ligand-Target Pair
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US Patent
LigandPNGBDBM112826(US8629167, 37)
Affinity DataIC50:  0.200nMAssay Description:In order to demonstrate the utility of the compounds of this invention, an androgen receptor binding assay was performed wherein many of the compound...More data for this Ligand-Target Pair
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US Patent
LigandPNGBDBM112824(US8629167, 35)
Affinity DataIC50:  0.200nMAssay Description:In order to demonstrate the utility of the compounds of this invention, an androgen receptor binding assay was performed wherein many of the compound...More data for this Ligand-Target Pair
In DepthDetails US Patent
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US Patent
LigandPNGBDBM112819(US8629167, 30)
Affinity DataIC50:  0.300nMAssay Description:In order to demonstrate the utility of the compounds of this invention, an androgen receptor binding assay was performed wherein many of the compound...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAndrogen receptor(Rattus norvegicus (Rat))
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US Patent
LigandPNGBDBM112797(US8629167, 7)
Affinity DataIC50:  0.400nMAssay Description:In order to demonstrate the utility of the compounds of this invention, an androgen receptor binding assay was performed wherein many of the compound...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAndrogen receptor(Rattus norvegicus (Rat))
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US Patent
LigandPNGBDBM112805(US8629167, 15)
Affinity DataIC50:  0.5nMAssay Description:In order to demonstrate the utility of the compounds of this invention, an androgen receptor binding assay was performed wherein many of the compound...More data for this Ligand-Target Pair
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US Patent
LigandPNGBDBM112812(US8629167, 23)
Affinity DataIC50:  0.700nMAssay Description:In order to demonstrate the utility of the compounds of this invention, an androgen receptor binding assay was performed wherein many of the compound...More data for this Ligand-Target Pair
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US Patent
LigandPNGBDBM112841(US8629167, 53)
Affinity DataIC50:  1nMAssay Description:In order to demonstrate the utility of the compounds of this invention, an androgen receptor binding assay was performed wherein many of the compound...More data for this Ligand-Target Pair
In DepthDetails US Patent
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US Patent
LigandPNGBDBM112836(US8629167, 47)
Affinity DataIC50:  1nMAssay Description:In order to demonstrate the utility of the compounds of this invention, an androgen receptor binding assay was performed wherein many of the compound...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAndrogen receptor(Rattus norvegicus (Rat))
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US Patent
LigandPNGBDBM112882(US8629167, 95)
Affinity DataIC50:  1nMAssay Description:In order to demonstrate the utility of the compounds of this invention, an androgen receptor binding assay was performed wherein many of the compound...More data for this Ligand-Target Pair
In DepthDetails US Patent
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US Patent
LigandPNGBDBM112867(US8629167, 80)
Affinity DataIC50:  1nMAssay Description:In order to demonstrate the utility of the compounds of this invention, an androgen receptor binding assay was performed wherein many of the compound...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAndrogen receptor(Rattus norvegicus (Rat))
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US Patent
LigandPNGBDBM18161((1S,2S,7S,10R,11S,14S,15S)-14-hydroxy-2,15-dimethy...)
Affinity DataIC50:  1nMAssay Description:Displacement of [3H]-MIB from wild-type rat AR LBD measured after 16 hrs by scintillation counting methodMore data for this Ligand-Target Pair
TargetAndrogen receptor(Rattus norvegicus (Rat))
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US Patent
LigandPNGBDBM112842(US8629167, 54)
Affinity DataIC50:  1nMAssay Description:In order to demonstrate the utility of the compounds of this invention, an androgen receptor binding assay was performed wherein many of the compound...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAndrogen receptor(Rattus norvegicus (Rat))
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US Patent
LigandPNGBDBM112853(US8629167, 65)
Affinity DataIC50:  1nMAssay Description:In order to demonstrate the utility of the compounds of this invention, an androgen receptor binding assay was performed wherein many of the compound...More data for this Ligand-Target Pair
In DepthDetails US Patent
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US Patent
LigandPNGBDBM26258((1S,2R,9R,10R,11S,14S,15S)-14-hydroxy-9,14,15-trim...)
Affinity DataIC50:  1nMAssay Description:Displacement of [3H]-MIB from rat prostate cytosolic androgen receptor by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Rattus norvegicus (Rat))
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US Patent
LigandPNGBDBM112852(US8629167, 64)
Affinity DataIC50:  1nMAssay Description:In order to demonstrate the utility of the compounds of this invention, an androgen receptor binding assay was performed wherein many of the compound...More data for this Ligand-Target Pair
In DepthDetails US Patent
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US Patent
LigandPNGBDBM112851(US8629167, 63)
Affinity DataIC50:  1nMAssay Description:In order to demonstrate the utility of the compounds of this invention, an androgen receptor binding assay was performed wherein many of the compound...More data for this Ligand-Target Pair
In DepthDetails US Patent
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US Patent
LigandPNGBDBM112849(US8629167, 61)
Affinity DataIC50:  1nMAssay Description:In order to demonstrate the utility of the compounds of this invention, an androgen receptor binding assay was performed wherein many of the compound...More data for this Ligand-Target Pair
In DepthDetails US Patent
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US Patent
LigandPNGBDBM112865(US8629167, 78)
Affinity DataIC50:  1nMAssay Description:In order to demonstrate the utility of the compounds of this invention, an androgen receptor binding assay was performed wherein many of the compound...More data for this Ligand-Target Pair
In DepthDetails US Patent
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US Patent
LigandPNGBDBM50367916(METHYLTRIENOLONE | Metribolone | R-1881)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of rat AR-mediated reporter gene expression in COS7 cellsMore data for this Ligand-Target Pair
TargetAndrogen receptor(Rattus norvegicus (Rat))
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US Patent
LigandPNGBDBM50025425(17-Hydroxy-10,13-dimethyl-4,5,6,7,8,9,10,11,12,13,...)
Affinity DataIC50:  1.5nMAssay Description:In vitro antagonist activity against rat prostatic androgen receptor (AR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Rattus norvegicus (Rat))
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US Patent
LigandPNGBDBM50367916(METHYLTRIENOLONE | Metribolone | R-1881)
Affinity DataIC50:  1.5nMAssay Description:Binding affinity to rat Androgen receptor in African green monkey COS-7 cells measured by whole-cell binding assayMore data for this Ligand-Target Pair
TargetAndrogen receptor(Rattus norvegicus (Rat))
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US Patent
LigandPNGBDBM26258((1S,2R,9R,10R,11S,14S,15S)-14-hydroxy-9,14,15-trim...)
Affinity DataIC50:  1.66nMAssay Description:Inhibitory concentration against recombinant rat androgen receptor expressed in Escherichia coli using [3H]methyltrienolone (R 1881)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Rattus norvegicus (Rat))
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US Patent
LigandPNGBDBM18161((1S,2S,7S,10R,11S,14S,15S)-14-hydroxy-2,15-dimethy...)
Affinity DataIC50:  2nMAssay Description:Displacement of [3H]testosterone from androgen receptor in Sprague-Dawley rat prostate gland after 2 hrs by liquid scintillation countingChecked by AuthorMore data for this Ligand-Target Pair
TargetAndrogen receptor(Rattus norvegicus (Rat))
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US Patent
LigandPNGBDBM112868(US8629167, 81)
Affinity DataIC50:  2nMAssay Description:In order to demonstrate the utility of the compounds of this invention, an androgen receptor binding assay was performed wherein many of the compound...More data for this Ligand-Target Pair
In DepthDetails US Patent
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US Patent
LigandPNGBDBM112866(US8629167, 79)
Affinity DataIC50:  2nMAssay Description:In order to demonstrate the utility of the compounds of this invention, an androgen receptor binding assay was performed wherein many of the compound...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAndrogen receptor(Rattus norvegicus (Rat))
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US Patent
LigandPNGBDBM112885(US8629167, 49)
Affinity DataIC50:  2nMAssay Description:In order to demonstrate the utility of the compounds of this invention, an androgen receptor binding assay was performed wherein many of the compound...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAndrogen receptor(Rattus norvegicus (Rat))
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US Patent
LigandPNGBDBM112821(US8629167, 32)
Affinity DataIC50:  2nMAssay Description:In order to demonstrate the utility of the compounds of this invention, an androgen receptor binding assay was performed wherein many of the compound...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAndrogen receptor(Rattus norvegicus (Rat))
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US Patent
LigandPNGBDBM112811(US8629167, 22)
Affinity DataIC50:  2nMAssay Description:In order to demonstrate the utility of the compounds of this invention, an androgen receptor binding assay was performed wherein many of the compound...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAndrogen receptor(Rattus norvegicus (Rat))
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US Patent
LigandPNGBDBM18161((1S,2S,7S,10R,11S,14S,15S)-14-hydroxy-2,15-dimethy...)
Affinity DataIC50:  2.20nMAssay Description:In vitro antagonist activity against rat prostatic androgen receptor (AR)More data for this Ligand-Target Pair
TargetAndrogen receptor(Rattus norvegicus (Rat))
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US Patent
LigandPNGBDBM50410541(CHEMBL194467)
Affinity DataIC50:  2.24nMAssay Description:Inhibitory concentration against recombinant rat androgen receptor expressed in Escherichia coli using [3H]methyltrienolone (R 1881)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Rattus norvegicus (Rat))
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US Patent
LigandPNGBDBM50025417(7-Hydroxy-1,4a,6a-trimethyl-1,4a,4b,5,6,6a,7,8,9,9...)
Affinity DataIC50:  2.40nMAssay Description:In vitro antagonist activity against rat prostatic androgen receptor (AR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Rattus norvegicus (Rat))
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US Patent
LigandPNGBDBM50410489(TRENBOLONE)
Affinity DataIC50:  2.63nMAssay Description:Inhibitory concentration against recombinant rat androgen receptor expressed in Escherichia coli using [3H]methyltrienolone (R 1881)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Rattus norvegicus (Rat))
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US Patent
LigandPNGBDBM112810(US8629167, 21)
Affinity DataIC50:  3nMAssay Description:In order to demonstrate the utility of the compounds of this invention, an androgen receptor binding assay was performed wherein many of the compound...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAndrogen receptor(Rattus norvegicus (Rat))
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US Patent
LigandPNGBDBM112791(US8629167, 1)
Affinity DataIC50:  3nMAssay Description:In order to demonstrate the utility of the compounds of this invention, an androgen receptor binding assay was performed wherein many of the compound...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAndrogen receptor(Rattus norvegicus (Rat))
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US Patent
LigandPNGBDBM112832(US8629167, 43)
Affinity DataIC50:  3nMAssay Description:In order to demonstrate the utility of the compounds of this invention, an androgen receptor binding assay was performed wherein many of the compound...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAndrogen receptor(Rattus norvegicus (Rat))
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US Patent
LigandPNGBDBM50367916(METHYLTRIENOLONE | Metribolone | R-1881)
Affinity DataIC50:  3.09nMAssay Description:Inhibitory concentration against recombinant rat androgen receptor expressed in Escherichia coli using [3H]methyltrienolone (R 1881)More data for this Ligand-Target Pair
TargetAndrogen receptor(Rattus norvegicus (Rat))
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US Patent
LigandPNGBDBM18161((1S,2S,7S,10R,11S,14S,15S)-14-hydroxy-2,15-dimethy...)
Affinity DataIC50:  3.10nMAssay Description:Competitive binding affinity to rat androgen receptorChecked by AuthorMore data for this Ligand-Target Pair
TargetAndrogen receptor(Rattus norvegicus (Rat))
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US Patent
LigandPNGBDBM18161((1S,2S,7S,10R,11S,14S,15S)-14-hydroxy-2,15-dimethy...)
Affinity DataIC50:  3.10nMAssay Description:Displacement of [3H]testosterone from Sprague-Dawley rat AR by liquid scintillation countingMore data for this Ligand-Target Pair
TargetAndrogen receptor(Rattus norvegicus (Rat))
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US Patent
LigandPNGBDBM8885((1S,2R,10R,11S,14S,15S)-14-hydroxy-2,15-dimethylte...)
Affinity DataIC50:  3.20nMAssay Description:In vitro antagonist activity against rat prostatic androgen receptor (AR)More data for this Ligand-Target Pair
TargetAndrogen receptor(Rattus norvegicus (Rat))
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US Patent
LigandPNGBDBM112823(US8629167, 34)
Affinity DataIC50:  4nMAssay Description:In order to demonstrate the utility of the compounds of this invention, an androgen receptor binding assay was performed wherein many of the compound...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAndrogen receptor(Rattus norvegicus (Rat))
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US Patent
LigandPNGBDBM112858(US8629167, 70)
Affinity DataIC50:  4nMAssay Description:In order to demonstrate the utility of the compounds of this invention, an androgen receptor binding assay was performed wherein many of the compound...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAndrogen receptor(Rattus norvegicus (Rat))
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US Patent
LigandPNGBDBM180890(US9133182, Example 19)
Affinity DataIC50:  4nMAssay Description:In order to demonstrate the utility of the compounds of this invention, an androgen receptor binding assay was performed wherein many of the compound...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAndrogen receptor(Rattus norvegicus (Rat))
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US Patent
LigandPNGBDBM112803(US8629167, 13)
Affinity DataIC50:  5nMAssay Description:In order to demonstrate the utility of the compounds of this invention, an androgen receptor binding assay was performed wherein many of the compound...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAndrogen receptor(Rattus norvegicus (Rat))
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US Patent
LigandPNGBDBM112833(US8629167, 44)
Affinity DataIC50:  5nMAssay Description:In order to demonstrate the utility of the compounds of this invention, an androgen receptor binding assay was performed wherein many of the compound...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAndrogen receptor(Rattus norvegicus (Rat))
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US Patent
LigandPNGBDBM112792(US8629167, 2)
Affinity DataIC50:  5nMAssay Description:In order to demonstrate the utility of the compounds of this invention, an androgen receptor binding assay was performed wherein many of the compound...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAndrogen receptor(Rattus norvegicus (Rat))
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US Patent
LigandPNGBDBM112838(US8629167, 50)
Affinity DataIC50:  5nMAssay Description:In order to demonstrate the utility of the compounds of this invention, an androgen receptor binding assay was performed wherein many of the compound...More data for this Ligand-Target Pair
In DepthDetails US Patent
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