Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Aldehyde dehydrogenase (ALDH2) (Homo sapiens (Human)) | BDBM118233![]() (US8673966, tert-butyl (1-(3-((3-(4-(methylsulfonam...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | n/a | n/a | 2.30 | n/a | n/a | n/a | n/a | n/a | n/a | |
Gilead Sciences, Inc. US Patent | Assay Description Standard ALDH2 reaction mixtures contained 150 uM formaldehyde, 2.5 mM NAD+, 10 mM MgCl2 and 10 nM recombinant human ALDH2 in 50 mM Hepes buffer, pH ... | US Patent US8673966 (2014) BindingDB Entry DOI: 10.7270/Q2QZ28MX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldehyde dehydrogenase (ALDH2) (Homo sapiens (Human)) | BDBM50093535![]() (11-(3-(4-hydroxyphenyl)-4-oxo-4H-chromen-7-yloxy)u...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Harvard Medical School Curated by ChEMBL | Assay Description Inhibition of Hamster Liver mitochondrial ALDH-2 | J Med Chem 43: 4169-79 (2000) Article DOI: 10.1021/jm990614i BindingDB Entry DOI: 10.7270/Q2GX49T8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldehyde dehydrogenase (ALDH2) (Homo sapiens (Human)) | BDBM118229![]() (US8673966, N-(4-(7-((1-(cyclobutanecarbonyl)azetid...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a | |
Gilead Sciences, Inc. US Patent | Assay Description Standard ALDH2 reaction mixtures contained 150 uM formaldehyde, 2.5 mM NAD+, 10 mM MgCl2 and 10 nM recombinant human ALDH2 in 50 mM Hepes buffer, pH ... | US Patent US8673966 (2014) BindingDB Entry DOI: 10.7270/Q2QZ28MX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldehyde dehydrogenase (ALDH2) (Homo sapiens (Human)) | BDBM50093537![]() (10-(3-(4-hydroxyphenyl)-4-oxo-4H-chromen-7-yloxy)d...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Harvard Medical School Curated by ChEMBL | Assay Description Inhibition of Hamster Liver mitochondrial ALDH-2 | J Med Chem 43: 4169-79 (2000) Article DOI: 10.1021/jm990614i BindingDB Entry DOI: 10.7270/Q2GX49T8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldehyde dehydrogenase (ALDH2) (Homo sapiens (Human)) | BDBM118196![]() (US8673966, N-(4-(7-((1-methyl-1H-imidazol-5-yl)eth...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | n/a | n/a | <4.90 | n/a | n/a | n/a | n/a | n/a | n/a | |
Gilead Sciences, Inc. US Patent | Assay Description Standard ALDH2 reaction mixtures contained 150 uM formaldehyde, 2.5 mM NAD+, 10 mM MgCl2 and 10 nM recombinant human ALDH2 in 50 mM Hepes buffer, pH ... | US Patent US8673966 (2014) BindingDB Entry DOI: 10.7270/Q2QZ28MX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldehyde dehydrogenase (ALDH2) (Homo sapiens (Human)) | BDBM118228![]() (US8673966, N-(4-(7-((1-(2,2-difluorocyclopropane- ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a | |
Gilead Sciences, Inc. US Patent | Assay Description Standard ALDH2 reaction mixtures contained 150 uM formaldehyde, 2.5 mM NAD+, 10 mM MgCl2 and 10 nM recombinant human ALDH2 in 50 mM Hepes buffer, pH ... | US Patent US8673966 (2014) BindingDB Entry DOI: 10.7270/Q2QZ28MX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldehyde dehydrogenase (ALDH2) (Homo sapiens (Human)) | BDBM118223![]() (US8673966, N-(4-(7-((1-(3-hydroxy-3-methylcyclobut...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a | |
Gilead Sciences, Inc. US Patent | Assay Description Standard ALDH2 reaction mixtures contained 150 uM formaldehyde, 2.5 mM NAD+, 10 mM MgCl2 and 10 nM recombinant human ALDH2 in 50 mM Hepes buffer, pH ... | US Patent US8673966 (2014) BindingDB Entry DOI: 10.7270/Q2QZ28MX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldehyde dehydrogenase (ALDH2) (Homo sapiens (Human)) | BDBM118232![]() (US8673966, tert-butyl 1-(3-((3-(4- (methylsulfonam...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a | |
Gilead Sciences, Inc. US Patent | Assay Description Standard ALDH2 reaction mixtures contained 150 uM formaldehyde, 2.5 mM NAD+, 10 mM MgCl2 and 10 nM recombinant human ALDH2 in 50 mM Hepes buffer, pH ... | US Patent US8673966 (2014) BindingDB Entry DOI: 10.7270/Q2QZ28MX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldehyde dehydrogenase (ALDH2) (Homo sapiens (Human)) | BDBM118209![]() (US8673966, N-(4-(7-((1-(cyclopropanecarbonyl)azeti...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a | |
Gilead Sciences, Inc. US Patent | Assay Description Standard ALDH2 reaction mixtures contained 150 uM formaldehyde, 2.5 mM NAD+, 10 mM MgCl2 and 10 nM recombinant human ALDH2 in 50 mM Hepes buffer, pH ... | US Patent US8673966 (2014) BindingDB Entry DOI: 10.7270/Q2QZ28MX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldehyde dehydrogenase (ALDH2) (Homo sapiens (Human)) | BDBM118231![]() (US8673966, tert-butyl 1-(3-((3-(4-(methylsulfonami...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a | |
Gilead Sciences, Inc. US Patent | Assay Description Standard ALDH2 reaction mixtures contained 150 uM formaldehyde, 2.5 mM NAD+, 10 mM MgCl2 and 10 nM recombinant human ALDH2 in 50 mM Hepes buffer, pH ... | US Patent US8673966 (2014) BindingDB Entry DOI: 10.7270/Q2QZ28MX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldehyde dehydrogenase (ALDH2) (Homo sapiens (Human)) | BDBM118220![]() (US8673966, N-(4-(7-((1-(3,3-difluorocyclobutanecar...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a | |
Gilead Sciences, Inc. US Patent | Assay Description Standard ALDH2 reaction mixtures contained 150 uM formaldehyde, 2.5 mM NAD+, 10 mM MgCl2 and 10 nM recombinant human ALDH2 in 50 mM Hepes buffer, pH ... | US Patent US8673966 (2014) BindingDB Entry DOI: 10.7270/Q2QZ28MX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldehyde dehydrogenase (ALDH2) (Homo sapiens (Human)) | BDBM118230![]() (US8673966, N-(4-(7-((1-(1-methylcyclopropanecarbon...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a | |
Gilead Sciences, Inc. US Patent | Assay Description Standard ALDH2 reaction mixtures contained 150 uM formaldehyde, 2.5 mM NAD+, 10 mM MgCl2 and 10 nM recombinant human ALDH2 in 50 mM Hepes buffer, pH ... | US Patent US8673966 (2014) BindingDB Entry DOI: 10.7270/Q2QZ28MX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldehyde dehydrogenase (ALDH2) (Homo sapiens (Human)) | BDBM118225![]() (US8673966, N-(4-(7-((1-(3-methyloxetane-3- carbony...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a | |
Gilead Sciences, Inc. US Patent | Assay Description Standard ALDH2 reaction mixtures contained 150 uM formaldehyde, 2.5 mM NAD+, 10 mM MgCl2 and 10 nM recombinant human ALDH2 in 50 mM Hepes buffer, pH ... | US Patent US8673966 (2014) BindingDB Entry DOI: 10.7270/Q2QZ28MX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldehyde dehydrogenase (ALDH2) (Homo sapiens (Human)) | BDBM118211![]() (US8673966, N-(4-(7-((1-(cyclopropanecarbonyl)piper...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | n/a | n/a | 6.5 | n/a | n/a | n/a | n/a | n/a | n/a | |
Gilead Sciences, Inc. US Patent | Assay Description Standard ALDH2 reaction mixtures contained 150 uM formaldehyde, 2.5 mM NAD+, 10 mM MgCl2 and 10 nM recombinant human ALDH2 in 50 mM Hepes buffer, pH ... | US Patent US8673966 (2014) BindingDB Entry DOI: 10.7270/Q2QZ28MX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldehyde dehydrogenase (ALDH2) (Homo sapiens (Human)) | BDBM118213![]() (US8673966, N-(4-(7-((1-isopropyl-1H-imidazol-5- yl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a | |
Gilead Sciences, Inc. US Patent | Assay Description Standard ALDH2 reaction mixtures contained 150 uM formaldehyde, 2.5 mM NAD+, 10 mM MgCl2 and 10 nM recombinant human ALDH2 in 50 mM Hepes buffer, pH ... | US Patent US8673966 (2014) BindingDB Entry DOI: 10.7270/Q2QZ28MX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldehyde dehydrogenase (ALDH2) (Homo sapiens (Human)) | BDBM118219![]() (US8673966, N-(4-(7-((1-(3-methoxypropanoyl)azetidi...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a | |
Gilead Sciences, Inc. US Patent | Assay Description Standard ALDH2 reaction mixtures contained 150 uM formaldehyde, 2.5 mM NAD+, 10 mM MgCl2 and 10 nM recombinant human ALDH2 in 50 mM Hepes buffer, pH ... | US Patent US8673966 (2014) BindingDB Entry DOI: 10.7270/Q2QZ28MX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldehyde dehydrogenase (ALDH2) (Homo sapiens (Human)) | BDBM118216![]() (US8673966, cyclopentyl 3-((3-(4- (methylsulfonamid...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a | |
Gilead Sciences, Inc. US Patent | Assay Description Standard ALDH2 reaction mixtures contained 150 uM formaldehyde, 2.5 mM NAD+, 10 mM MgCl2 and 10 nM recombinant human ALDH2 in 50 mM Hepes buffer, pH ... | US Patent US8673966 (2014) BindingDB Entry DOI: 10.7270/Q2QZ28MX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldehyde dehydrogenase (ALDH2) (Homo sapiens (Human)) | BDBM118207![]() (US8673966, tert-butyl 3-((3-(4-(methylsulfonamido)...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a | |
Gilead Sciences, Inc. US Patent | Assay Description Standard ALDH2 reaction mixtures contained 150 uM formaldehyde, 2.5 mM NAD+, 10 mM MgCl2 and 10 nM recombinant human ALDH2 in 50 mM Hepes buffer, pH ... | US Patent US8673966 (2014) BindingDB Entry DOI: 10.7270/Q2QZ28MX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldehyde dehydrogenase (ALDH2) (Homo sapiens (Human)) | BDBM118208![]() (US8673966, N-(4-(4-oxo-7-((2-oxo-1,2-dihydropyridi...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a | |
Gilead Sciences, Inc. US Patent | Assay Description Standard ALDH2 reaction mixtures contained 150 uM formaldehyde, 2.5 mM NAD+, 10 mM MgCl2 and 10 nM recombinant human ALDH2 in 50 mM Hepes buffer, pH ... | US Patent US8673966 (2014) BindingDB Entry DOI: 10.7270/Q2QZ28MX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldehyde dehydrogenase (ALDH2) (Homo sapiens (Human)) | BDBM50093531![]() (6-[3-(4-Hydroxy-phenyl)-4-oxo-4H-chromen-7-yloxy]-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
Harvard Medical School Curated by ChEMBL | Assay Description Inhibition of Hamster Liver mitochondrial ALDH-2 | J Med Chem 43: 4169-79 (2000) Article DOI: 10.1021/jm990614i BindingDB Entry DOI: 10.7270/Q2GX49T8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldehyde dehydrogenase (ALDH2) (Homo sapiens (Human)) | BDBM50093534![]() (7-[3-(4-Hydroxy-phenyl)-4-oxo-4H-chromen-7-yloxy]-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
Harvard Medical School Curated by ChEMBL | Assay Description Inhibition of Hamster Liver mitochondrial ALDH-2 | J Med Chem 43: 4169-79 (2000) Article DOI: 10.1021/jm990614i BindingDB Entry DOI: 10.7270/Q2GX49T8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldehyde dehydrogenase (ALDH2) (Homo sapiens (Human)) | BDBM118222![]() (US8673966, N-(4-(7-((1-(2-hydroxyacetyl)azetidin-3...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a | |
Gilead Sciences, Inc. US Patent | Assay Description Standard ALDH2 reaction mixtures contained 150 uM formaldehyde, 2.5 mM NAD+, 10 mM MgCl2 and 10 nM recombinant human ALDH2 in 50 mM Hepes buffer, pH ... | US Patent US8673966 (2014) BindingDB Entry DOI: 10.7270/Q2QZ28MX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldehyde dehydrogenase (ALDH2) (Homo sapiens (Human)) | BDBM118212![]() (US8673966, N-(4-(7-((1,2-dimethyl-1H-imidazol-5- y...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a | |
Gilead Sciences, Inc. US Patent | Assay Description Standard ALDH2 reaction mixtures contained 150 uM formaldehyde, 2.5 mM NAD+, 10 mM MgCl2 and 10 nM recombinant human ALDH2 in 50 mM Hepes buffer, pH ... | US Patent US8673966 (2014) BindingDB Entry DOI: 10.7270/Q2QZ28MX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldehyde dehydrogenase (ALDH2) (Homo sapiens (Human)) | BDBM118226![]() (US8673966, N-(4-(7-((1-(2-hydroxypropanoyl)azetidi...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a | |
Gilead Sciences, Inc. US Patent | Assay Description Standard ALDH2 reaction mixtures contained 150 uM formaldehyde, 2.5 mM NAD+, 10 mM MgCl2 and 10 nM recombinant human ALDH2 in 50 mM Hepes buffer, pH ... | US Patent US8673966 (2014) BindingDB Entry DOI: 10.7270/Q2QZ28MX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldehyde dehydrogenase (ALDH2) (Homo sapiens (Human)) | BDBM118224![]() (US8673966, N-(4-(7-((1-(2-hydroxy-2-methylpropanoy...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a | |
Gilead Sciences, Inc. US Patent | Assay Description Standard ALDH2 reaction mixtures contained 150 uM formaldehyde, 2.5 mM NAD+, 10 mM MgCl2 and 10 nM recombinant human ALDH2 in 50 mM Hepes buffer, pH ... | US Patent US8673966 (2014) BindingDB Entry DOI: 10.7270/Q2QZ28MX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldehyde dehydrogenase (ALDH2) (Homo sapiens (Human)) | BDBM118203![]() (US8673966, N-(4-(4-oxo-7-(pyridin-3-ylethynyl)-4H-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a | |
Gilead Sciences, Inc. US Patent | Assay Description Standard ALDH2 reaction mixtures contained 150 uM formaldehyde, 2.5 mM NAD+, 10 mM MgCl2 and 10 nM recombinant human ALDH2 in 50 mM Hepes buffer, pH ... | US Patent US8673966 (2014) BindingDB Entry DOI: 10.7270/Q2QZ28MX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldehyde dehydrogenase (ALDH2) (Homo sapiens (Human)) | BDBM153687![]() (US9000015, 4) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a | |
Gilead Sciences, Inc. US Patent | Assay Description Standard ALDH2 reaction mixtures contained 150 uM formaldehyde, 2.5 mM NAD+, 10 mM MgCl2 and 10 nM recombinant human ALDH2 in 50 mM Hepes buffer, pH ... | US Patent US9000015 (2015) BindingDB Entry DOI: 10.7270/Q28S4NNX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldehyde dehydrogenase (ALDH2) (Homo sapiens (Human)) | BDBM153696![]() (US9000015, 13) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | n/a | |
Gilead Sciences, Inc. US Patent | Assay Description Standard ALDH2 reaction mixtures contained 150 uM formaldehyde, 2.5 mM NAD+, 10 mM MgCl2 and 10 nM recombinant human ALDH2 in 50 mM Hepes buffer, pH ... | US Patent US9000015 (2015) BindingDB Entry DOI: 10.7270/Q28S4NNX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldehyde dehydrogenase (ALDH2) (Homo sapiens (Human)) | BDBM118227![]() (US8673966, N-(4-(7-((1-(1-methylpiperidine-4- carb...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | n/a | n/a | 35 | n/a | n/a | n/a | n/a | n/a | n/a | |
Gilead Sciences, Inc. US Patent | Assay Description Standard ALDH2 reaction mixtures contained 150 uM formaldehyde, 2.5 mM NAD+, 10 mM MgCl2 and 10 nM recombinant human ALDH2 in 50 mM Hepes buffer, pH ... | US Patent US8673966 (2014) BindingDB Entry DOI: 10.7270/Q2QZ28MX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldehyde dehydrogenase (ALDH2) (Homo sapiens (Human)) | BDBM50093535![]() (11-(3-(4-hydroxyphenyl)-4-oxo-4H-chromen-7-yloxy)u...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
Harvard Medical School Curated by ChEMBL | Assay Description Inhibition of hamster liver aldehyde dehydrogenase ALDH-2 | J Med Chem 44: 3320-8 (2001) Article DOI: 10.1021/jm0101390 BindingDB Entry DOI: 10.7270/Q2CC0ZZZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldehyde dehydrogenase (ALDH2) (Homo sapiens (Human)) | BDBM50409029![]() (DAIDZIN) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars | MMDB PDB Article PubMed | n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
Harvard Medical School Curated by ChEMBL | Assay Description Inhibition of Hamster Liver mitochondrial ALDH-2 | J Med Chem 43: 4169-79 (2000) Article DOI: 10.1021/jm990614i BindingDB Entry DOI: 10.7270/Q2GX49T8 | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Aldehyde dehydrogenase (ALDH2) (Homo sapiens (Human)) | BDBM50104896![]() (7-(2-(2-(2-hydroxyethoxy)ethoxy)ethoxy)-3-(4-hydro...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
Harvard Medical School Curated by ChEMBL | Assay Description Inhibition of hamster liver aldehyde dehydrogenase ALDH-2 | J Med Chem 44: 3320-8 (2001) Article DOI: 10.1021/jm0101390 BindingDB Entry DOI: 10.7270/Q2CC0ZZZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldehyde dehydrogenase (ALDH2) (Homo sapiens (Human)) | BDBM50104892![]() (8-(3-(4-hydroxyphenyl)-4-oxo-4H-chromen-7-yloxy)oc...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
Harvard Medical School Curated by ChEMBL | Assay Description Inhibition of hamster liver aldehyde dehydrogenase ALDH-2 | J Med Chem 44: 3320-8 (2001) Article DOI: 10.1021/jm0101390 BindingDB Entry DOI: 10.7270/Q2CC0ZZZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldehyde dehydrogenase (ALDH2) (Homo sapiens (Human)) | BDBM50093538![]() (3-(4-Hydroxyphenyl)-7-ethoxychromen-4-one | 7-Etho...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
Harvard Medical School Curated by ChEMBL | Assay Description Inhibition of Hamster Liver mitochondrial ALDH-2 | J Med Chem 43: 4169-79 (2000) Article DOI: 10.1021/jm990614i BindingDB Entry DOI: 10.7270/Q2GX49T8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldehyde dehydrogenase (ALDH2) (Homo sapiens (Human)) | BDBM118217![]() (US8673966, N-(4-(4-oxo-7-((tetrahydro-2H-pyran-4- ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | n/a | n/a | 43 | n/a | n/a | n/a | n/a | n/a | n/a | |
Gilead Sciences, Inc. US Patent | Assay Description Standard ALDH2 reaction mixtures contained 150 uM formaldehyde, 2.5 mM NAD+, 10 mM MgCl2 and 10 nM recombinant human ALDH2 in 50 mM Hepes buffer, pH ... | US Patent US8673966 (2014) BindingDB Entry DOI: 10.7270/Q2QZ28MX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldehyde dehydrogenase (ALDH2) (Homo sapiens (Human)) | BDBM118197![]() (US8673966, N-(4-(7-(3-methoxyprop-1-ynyl)-4-oxo-4H...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | n/a | n/a | 47 | n/a | n/a | n/a | n/a | n/a | n/a | |
Gilead Sciences, Inc. US Patent | Assay Description Standard ALDH2 reaction mixtures contained 150 uM formaldehyde, 2.5 mM NAD+, 10 mM MgCl2 and 10 nM recombinant human ALDH2 in 50 mM Hepes buffer, pH ... | US Patent US8673966 (2014) BindingDB Entry DOI: 10.7270/Q2QZ28MX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldehyde dehydrogenase (ALDH2) (Homo sapiens (Human)) | BDBM50093534![]() (7-[3-(4-Hydroxy-phenyl)-4-oxo-4H-chromen-7-yloxy]-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
Harvard Medical School Curated by ChEMBL | Assay Description Inhibition of hamster liver aldehyde dehydrogenase ALDH-2 | J Med Chem 44: 3320-8 (2001) Article DOI: 10.1021/jm0101390 BindingDB Entry DOI: 10.7270/Q2CC0ZZZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldehyde dehydrogenase (ALDH2) (Homo sapiens (Human)) | BDBM50093537![]() (10-(3-(4-hydroxyphenyl)-4-oxo-4H-chromen-7-yloxy)d...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
Harvard Medical School Curated by ChEMBL | Assay Description Inhibition of hamster liver aldehyde dehydrogenase ALDH-2 | J Med Chem 44: 3320-8 (2001) Article DOI: 10.1021/jm0101390 BindingDB Entry DOI: 10.7270/Q2CC0ZZZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldehyde dehydrogenase (ALDH2) (Homo sapiens (Human)) | BDBM50448802![]() (CHEMBL3128207) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
Indiana University School of Medicine Curated by ChEMBL | Assay Description Inhibition of human ALDH2 using propionaldehyde as substrate preincubated for 2 mins followed by substrate addition by spectrophotometry in presence ... | J Med Chem 57: 714-22 (2014) Article DOI: 10.1021/jm401377v BindingDB Entry DOI: 10.7270/Q21V5GF2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldehyde dehydrogenase (ALDH2) (Homo sapiens (Human)) | BDBM118202![]() (US8673966, N-(4-(4-oxo-7-(pyrimidin-5-ylethynyl)-4...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | n/a | n/a | 57 | n/a | n/a | n/a | n/a | n/a | n/a | |
Gilead Sciences, Inc. US Patent | Assay Description Standard ALDH2 reaction mixtures contained 150 uM formaldehyde, 2.5 mM NAD+, 10 mM MgCl2 and 10 nM recombinant human ALDH2 in 50 mM Hepes buffer, pH ... | US Patent US8673966 (2014) BindingDB Entry DOI: 10.7270/Q2QZ28MX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldehyde dehydrogenase (ALDH2) (Homo sapiens (Human)) | BDBM118193![]() (US8673966, N-(4-(7-(cyclopropylethynyl)-4-oxo-4H- ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | n/a | n/a | 57.7 | n/a | n/a | n/a | n/a | n/a | n/a | |
Gilead Sciences, Inc. US Patent | Assay Description Standard ALDH2 reaction mixtures contained 150 uM formaldehyde, 2.5 mM NAD+, 10 mM MgCl2 and 10 nM recombinant human ALDH2 in 50 mM Hepes buffer, pH ... | US Patent US8673966 (2014) BindingDB Entry DOI: 10.7270/Q2QZ28MX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldehyde dehydrogenase (ALDH2) (Homo sapiens (Human)) | BDBM50093531![]() (6-[3-(4-Hydroxy-phenyl)-4-oxo-4H-chromen-7-yloxy]-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
Harvard Medical School Curated by ChEMBL | Assay Description Inhibition of hamster liver aldehyde dehydrogenase ALDH-2 | J Med Chem 44: 3320-8 (2001) Article DOI: 10.1021/jm0101390 BindingDB Entry DOI: 10.7270/Q2CC0ZZZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldehyde dehydrogenase (ALDH2) (Homo sapiens (Human)) | BDBM153684![]() (US9000015, 1) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | n/a | n/a | 63 | n/a | n/a | n/a | n/a | n/a | n/a | |
Gilead Sciences, Inc. US Patent | Assay Description Standard ALDH2 reaction mixtures contained 150 uM formaldehyde, 2.5 mM NAD+, 10 mM MgCl2 and 10 nM recombinant human ALDH2 in 50 mM Hepes buffer, pH ... | US Patent US9000015 (2015) BindingDB Entry DOI: 10.7270/Q28S4NNX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldehyde dehydrogenase (ALDH2) (Homo sapiens (Human)) | BDBM118221![]() (US8673966, N-(4-(7-((1-(3-(dimethylamino)propanoyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | n/a | n/a | 64 | n/a | n/a | n/a | n/a | n/a | n/a | |
Gilead Sciences, Inc. US Patent | Assay Description Standard ALDH2 reaction mixtures contained 150 uM formaldehyde, 2.5 mM NAD+, 10 mM MgCl2 and 10 nM recombinant human ALDH2 in 50 mM Hepes buffer, pH ... | US Patent US8673966 (2014) BindingDB Entry DOI: 10.7270/Q2QZ28MX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldehyde dehydrogenase (ALDH2) (Homo sapiens (Human)) | BDBM50104880![]() (7-(2-Hydroxy-ethoxy)-3-(4-hydroxy-phenyl)-chromen-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 70 | n/a | n/a | n/a | n/a | n/a | n/a |
Harvard Medical School Curated by ChEMBL | Assay Description Inhibition of hamster liver aldehyde dehydrogenase ALDH-2 | J Med Chem 44: 3320-8 (2001) Article DOI: 10.1021/jm0101390 BindingDB Entry DOI: 10.7270/Q2CC0ZZZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldehyde dehydrogenase (ALDH2) (Homo sapiens (Human)) | BDBM50104874![]() (3-(4-Hydroxy-phenyl)-7-isopropoxy-chromen-4-one | ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 80 | n/a | n/a | n/a | n/a | n/a | n/a |
Harvard Medical School Curated by ChEMBL | Assay Description Inhibition of hamster liver aldehyde dehydrogenase ALDH-2 | J Med Chem 44: 3320-8 (2001) Article DOI: 10.1021/jm0101390 BindingDB Entry DOI: 10.7270/Q2CC0ZZZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldehyde dehydrogenase (ALDH2) (Homo sapiens (Human)) | BDBM50409029![]() (DAIDZIN) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars | MMDB PDB Article PubMed | n/a | n/a | 80 | n/a | n/a | n/a | n/a | n/a | n/a |
Harvard Medical School Curated by ChEMBL | Assay Description Inhibition of hamster liver aldehyde dehydrogenase ALDH-2 | J Med Chem 44: 3320-8 (2001) Article DOI: 10.1021/jm0101390 BindingDB Entry DOI: 10.7270/Q2CC0ZZZ | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Aldehyde dehydrogenase (ALDH2) (Homo sapiens (Human)) | BDBM50093538![]() (3-(4-Hydroxyphenyl)-7-ethoxychromen-4-one | 7-Etho...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 80 | n/a | n/a | n/a | n/a | n/a | n/a |
Harvard Medical School Curated by ChEMBL | Assay Description Inhibition of hamster liver aldehyde dehydrogenase ALDH-2 | J Med Chem 44: 3320-8 (2001) Article DOI: 10.1021/jm0101390 BindingDB Entry DOI: 10.7270/Q2CC0ZZZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldehyde dehydrogenase (ALDH2) (Homo sapiens (Human)) | BDBM118206![]() (US8673966, tert-butyl 4-((3-(4-(methylsulfonamido)...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | n/a | n/a | 86 | n/a | n/a | n/a | n/a | n/a | n/a | |
Gilead Sciences, Inc. US Patent | Assay Description Standard ALDH2 reaction mixtures contained 150 uM formaldehyde, 2.5 mM NAD+, 10 mM MgCl2 and 10 nM recombinant human ALDH2 in 50 mM Hepes buffer, pH ... | US Patent US8673966 (2014) BindingDB Entry DOI: 10.7270/Q2QZ28MX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldehyde dehydrogenase (ALDH2) (Homo sapiens (Human)) | BDBM118200![]() (US8673966, N-(4-(4-oxo-7-(pyridin-2-ylethynyl)-4H-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | n/a | n/a | 90 | n/a | n/a | n/a | n/a | n/a | n/a | |
Gilead Sciences, Inc. US Patent | Assay Description Standard ALDH2 reaction mixtures contained 150 uM formaldehyde, 2.5 mM NAD+, 10 mM MgCl2 and 10 nM recombinant human ALDH2 in 50 mM Hepes buffer, pH ... | US Patent US8673966 (2014) BindingDB Entry DOI: 10.7270/Q2QZ28MX | |||||||||||
More data for this Ligand-Target Pair |
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