Compile Data Set for Download or QSAR
maximum 50k data
Found 2714 of ic50 data for polymerid = 6463
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50088301((E)-N,N-dimethyl-N-(4-(2-p-tolyl-6,7-dihydro-5H-be...)
Affinity DataIC50:  0.0300nMAssay Description:Displacement of [125I]MCP1 from CCR2/CXCR4 (unknown origin) expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50035696(1,1''-{1,4-phenylenebis(methylene)}-bis{1,4,8,11-t...)
Affinity DataIC50:  0.0400nMAssay Description:Displacement of [125I]SDF1alpha from CCR2/CXCR4 (unknown origin) expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50088301((E)-N,N-dimethyl-N-(4-(2-p-tolyl-6,7-dihydro-5H-be...)
Affinity DataIC50:  0.0800nMAssay Description:Displacement of [125I]SDF1alpha from CCR2/CXCR4 (unknown origin) expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50035696(1,1''-{1,4-phenylenebis(methylene)}-bis{1,4,8,11-t...)
Affinity DataIC50:  0.0900nMAssay Description:Displacement of [125I]MCP1 from CCR2/CXCR4 (unknown origin) expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50257994((1S,3R)-N-(3,5-bis(-trifluoromethyl)benzyl)-1-iso ...)
Affinity DataIC50:  0.100nMAssay Description:Antagonist activity at human CCR2 receptor expressed in CHO cells by chemotaxis assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50257994((1S,3R)-N-(3,5-bis(-trifluoromethyl)benzyl)-1-iso ...)
Affinity DataIC50:  0.100nMAssay Description:Antagonist activity at human CCR2 receptor expressed in CHO cells by chemotaxis assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50257994((1S,3R)-N-(3,5-bis(-trifluoromethyl)benzyl)-1-iso ...)
Affinity DataIC50:  0.100nMAssay Description:Antagonist activity at human CCR2 receptor expressed in CHO cells by chemotaxis assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50212136((1S,3R)-N-{[3-fluoro-5-(trifluoromethyl)phenyl]met...)
Affinity DataIC50:  0.150nMAssay Description:Inhibition of chemotaxis in human MCP1 monocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50009224(CHEMBL3233188)
Affinity DataIC50:  0.200nMAssay Description:Antagonist activity at CCR2 in human monocytes assessed as reduction of chemotaxis in presence of 0.1 M BSAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50009220(CHEMBL3233186)
Affinity DataIC50:  0.200nMAssay Description:Antagonist activity at CCR2 in human monocytes assessed as reduction of chemotaxis in presence of 0.1 M BSAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50268371(CHEMBL502247 | N-(2-((1S,2R,4R)-4-(isopropyl(methy...)
Affinity DataIC50:  0.200nMAssay Description:Antagonist activity at CCR2 in human PBMC assessed as MCP1-induced chemotaxisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50377038(CHEMBL258205)
Affinity DataIC50:  0.200nMAssay Description:Binding affinity at human CCR2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50212127((1S,3R)-1-cyclopropyl-N-{[3-fluoro-5-(trifluoromet...)
Affinity DataIC50:  0.230nMAssay Description:Inhibition of chemotaxis in human MCP1 monocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50089354(CHEMBL3577945)
Affinity DataIC50:  0.240nMAssay Description:Antagonist activity against CCR2 in human PBMC assessed as inhibition of MCP1-induced chemotaxis at 37 degCMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50088301((E)-N,N-dimethyl-N-(4-(2-p-tolyl-6,7-dihydro-5H-be...)
Affinity DataIC50:  0.25nMAssay Description:Displacement of [125I]MCP1 from CCR2 (unknown origin) expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50012008(CHEMBL3263286)
Affinity DataIC50:  0.25nMAssay Description:Displacement of labeled MCP-1 from human CCR2 expressed in THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50557876(CHEMBL4764460)
Affinity DataIC50:  0.300nMAssay Description:Antagonist activity at CCR2 in human THP1 cells assessed as reduction in MCP1-induced chemotaxis measured after 30 mins by calcein-AM dye based fluor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50315998(CHEMBL1090893 | N-((S)-1-((1S,2R,4R)-4-(ethyl(isop...)
Affinity DataIC50:  0.300nMAssay Description:Displacement of [125I]-MCP1 from CCR2 in human THP1 cells after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50257995((1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-3-(3-et...)
Affinity DataIC50:  0.300nMAssay Description:Antagonist activity at human CCR2 receptor expressed in CHO cells by chemotaxis assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50268423(CHEMBL497202 | N-(2-((1S,2R,4R)-4-(dimethylamino)-...)
Affinity DataIC50:  0.300nMAssay Description:Antagonist activity at CCR2 in human PBMC assessed as MCP1-induced calcium flux by fluorescence-imaging plate reader assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50212128((1R,3R)-N-{[3-fluoro-5-(trifluoromethyl)phenyl]met...)
Affinity DataIC50:  0.320nMAssay Description:Inhibition of chemotaxis in human MCP1 monocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50009220(CHEMBL3233186)
Affinity DataIC50:  0.340nMAssay Description:Displacement of [125I]-labeled human MCP1 from CCR2 in human PBMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50268423(CHEMBL497202 | N-(2-((1S,2R,4R)-4-(dimethylamino)-...)
Affinity DataIC50:  0.370nMAssay Description:Displacement of [125I]MCP1 from CCR2 in human PBMC by millipore filter plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50509862(CHEMBL4457723)
Affinity DataIC50:  0.400nMAssay Description:Displacement of [125I]MCP1 from CCR2 in human PBMC measured after 30 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50089366(CHEMBL3577948)
Affinity DataIC50:  0.400nMT: 2°CAssay Description:Inhibition of [125I]hMCP1 binding to CCR2 in human PBMC incubated for 30 mins at room temperatureMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50315992(CHEMBL1092678 | N-((S)-1-((1S,2R,4R)-4-(isopropyl(...)
Affinity DataIC50:  0.400nMAssay Description:Displacement of [125I]-MCP1 from CCR2 in human THP1 cells after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50198149((S)-1-(4-(1-(3,5-bis(trifluoromethyl)benzylamino)-...)
Affinity DataIC50:  0.430nMAssay Description:Antagonist activity at human CCR2b receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50198149((S)-1-(4-(1-(3,5-bis(trifluoromethyl)benzylamino)-...)
Affinity DataIC50:  0.430nMAssay Description:Displacement of [125I]MCP1 from human CCR2 expressed in monocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50089356(CHEMBL3577933)
Affinity DataIC50: <0.450nMAssay Description:Antagonist activity against CCR2 in human PBMC assessed as inhibition of MCP1-induced chemotaxis at 37 degCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50089355(CHEMBL3577932)
Affinity DataIC50: <0.450nMAssay Description:Antagonist activity against CCR2 in human PBMC assessed as inhibition of MCP1-induced chemotaxis at 37 degCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50268371(CHEMBL502247 | N-(2-((1S,2R,4R)-4-(isopropyl(methy...)
Affinity DataIC50:  0.5nMAssay Description:Antagonist activity at CCR2 in human PBMC assessed as MCP1-induced calcium flux by fluorescence-imaging plate reader assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50089364(CHEMBL3577946)
Affinity DataIC50:  0.5nMAssay Description:Antagonist activity against CCR2 in human PBMC assessed as inhibition of MCP1-induced chemotaxis at 37 degCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50089364(CHEMBL3577946)
Affinity DataIC50:  0.5nMT: 2°CAssay Description:Inhibition of [125I]hMCP1 binding to CCR2 in human PBMC incubated for 30 mins at room temperatureMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50382932(CHEMBL2029422)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of CCR2-mediated Erk phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50315993(CHEMBL1091605 | N-((S)-1-((1S,2R,4R)-4-(isopropyl(...)
Affinity DataIC50:  0.5nMAssay Description:Antagonist activity at CCR2 in human monocytes assessed as reduction of chemotaxis in presence of 0.1 M BSAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50009221(CHEMBL3233187)
Affinity DataIC50:  0.5nMAssay Description:Displacement of [125I]-labeled human MCP1 from CCR2 in human PBMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50315993(CHEMBL1091605 | N-((S)-1-((1S,2R,4R)-4-(isopropyl(...)
Affinity DataIC50:  0.5nMAssay Description:Antagonist activity at CCR2 in human PBMC assessed as inhibition of MCP1-induced chemotaxis after 45 mins in presence of 0.1 M bovine serum albuminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50371414(CHEMBL271828)
Affinity DataIC50:  0.5nMAssay Description:Antagonist activity at human CCR2 in PBMCs assessed as inhibition of chemotaxisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50377034(CHEMBL256301)
Affinity DataIC50:  0.600nMAssay Description:Binding affinity at human CCR2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50198115(CHEMBL438304 | N-{[3,5-bis(trifluoromethyl)phenyl]...)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of MCP1-stimulated chemotaxis in monocytes transfected with human CCR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50089353(CHEMBL3577942)
Affinity DataIC50:  0.600nMAssay Description:Antagonist activity against CCR2 in human PBMC assessed as inhibition of MCP1-induced chemotaxis at 37 degCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50009217(CHEMBL3233184)
Affinity DataIC50:  0.600nMAssay Description:Antagonist activity at CCR2 in human monocytes assessed as reduction of chemotaxis in presence of 0.1 M BSAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50557877(CHEMBL4790208)
Affinity DataIC50:  0.600nMAssay Description:Antagonist activity at CCR2 in human THP1 cells assessed as reduction in MCP1-induced chemotaxis measured after 30 mins by calcein-AM dye based fluor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50377039(CHEMBL257191)
Affinity DataIC50:  0.600nMAssay Description:Binding affinity at human CCR2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50212127((1S,3R)-1-cyclopropyl-N-{[3-fluoro-5-(trifluoromet...)
Affinity DataIC50:  0.630nMAssay Description:Inhibition of Ca2+ flux in human monocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50509860(CHEMBL4442783)
Affinity DataIC50:  0.670nMAssay Description:Inhibition of CCR2 in human THP1 cells assessed as reduction in MCP1-induced chemotaxis measured after 10 mins by calcein-AM dye based fluorescence a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50089354(CHEMBL3577945)
Affinity DataIC50:  0.700nMAssay Description:Displacement of [125I]MCP1 from CCR2 in human PBMC measured after 30 minsMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50509860(CHEMBL4442783)
Affinity DataIC50:  0.700nMAssay Description:Antagonist activity at CCR2 in human THP1 cells assessed as reduction in MCP1-induced chemotaxis measured after 30 mins by calcein-AM dye based fluor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50509860(CHEMBL4442783)
Affinity DataIC50:  0.700nMAssay Description:Antagonist activity at CCR2 in human THP-1 cells assessed as reduction in CCL2-induced chemotaxisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50009214(CHEMBL3233181)
Affinity DataIC50:  0.700nMAssay Description:Displacement of [125I]-labeled human MCP1 from CCR2 in human PBMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 2714 total ) | Next | Last >>
Jump to: