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Compile Data Set for Download or QSAR

Found 71 hits of ec50 for UniProtKB: Q96S37   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM50239128
PNG
(CHEMBL4059854 | US10266493, Example 2A)
Show SMILES CC(C)(Sc1ccncc1-c1ccc(cc1)C#N)C(O)=O
Show InChI InChI=1S/C16H14N2O2S/c1-16(2,15(19)20)21-14-7-8-18-10-13(14)12-5-3-11(9-17)4-6-12/h3-8,10H,1-2H3,(H,19,20)
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Patents


Similars

US Patent
n/an/an/an/a 26n/an/an/an/a



Ardea Biosciences, Inc.

US Patent


Assay Description
HEK293 human embryonic kidney cells (ATCC# CRL-1573) were propagated in EMEM tissue culture medium as described by ATCC in an atmosphere of 5% CO2 an...


US Patent US10266493 (2019)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM377526
PNG
(US10266493, Example 2J)
Show SMILES OC(=O)C1(CCC1)Sc1ccncc1-c1ccc(C#N)c2ccccc12
Show InChI InChI=1S/C21H16N2O2S/c22-12-14-6-7-17(16-5-2-1-4-15(14)16)18-13-23-11-8-19(18)26-21(20(24)25)9-3-10-21/h1-2,4-8,11,13H,3,9-10H2,(H,24,25)
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n/an/an/an/a 26n/an/an/an/a



Ardea Biosciences, Inc.

US Patent


Assay Description
HEK293 human embryonic kidney cells (ATCC# CRL-1573) were propagated in EMEM tissue culture medium as described by ATCC in an atmosphere of 5% CO2 an...


US Patent US10266493 (2019)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM377530
PNG
(US10266493, Example 2O | US10266493, Example 2P)
Show SMILES CC(C)(Sc1ccncc1-c1ccc(Cl)cc1)C(O)=O
Show InChI InChI=1S/C15H14ClNO2S/c1-15(2,14(18)19)20-13-7-8-17-9-12(13)10-3-5-11(16)6-4-10/h3-9H,1-2H3,(H,18,19)
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n/an/an/an/a 26n/an/an/an/a



Ardea Biosciences, Inc.

US Patent


Assay Description
HEK293 human embryonic kidney cells (ATCC# CRL-1573) were propagated in EMEM tissue culture medium as described by ATCC in an atmosphere of 5% CO2 an...


US Patent US10266493 (2019)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM377530
PNG
(US10266493, Example 2O | US10266493, Example 2P)
Show SMILES CC(C)(Sc1ccncc1-c1ccc(Cl)cc1)C(O)=O
Show InChI InChI=1S/C15H14ClNO2S/c1-15(2,14(18)19)20-13-7-8-17-9-12(13)10-3-5-11(16)6-4-10/h3-9H,1-2H3,(H,18,19)
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n/an/an/an/a 26n/an/an/an/a



Ardea Biosciences, Inc.

US Patent


Assay Description
HEK293 human embryonic kidney cells (ATCC# CRL-1573) were propagated in EMEM tissue culture medium as described by ATCC in an atmosphere of 5% CO2 an...


US Patent US10266493 (2019)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM377538
PNG
(US10266493, Example 2X)
Show SMILES CC(C)(Sc1ccncc1-c1ccc(F)c2ccccc12)C(O)=O
Show InChI InChI=1S/C19H16FNO2S/c1-19(2,18(22)23)24-17-9-10-21-11-15(17)13-7-8-16(20)14-6-4-3-5-12(13)14/h3-11H,1-2H3,(H,22,23)
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n/an/an/an/a 26n/an/an/an/a



Ardea Biosciences, Inc.

US Patent


Assay Description
HEK293 human embryonic kidney cells (ATCC# CRL-1573) were propagated in EMEM tissue culture medium as described by ATCC in an atmosphere of 5% CO2 an...


US Patent US10266493 (2019)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM377548
PNG
(US10266493, Example 2JJ)
Show SMILES CC(C)(Sc1ccncc1-c1ccc(CO)cc1)C(O)=O
Show InChI InChI=1S/C16H17NO3S/c1-16(2,15(19)20)21-14-7-8-17-9-13(14)12-5-3-11(10-18)4-6-12/h3-9,18H,10H2,1-2H3,(H,19,20)
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n/an/an/an/a 26n/an/an/an/a



Ardea Biosciences, Inc.

US Patent


Assay Description
HEK293 human embryonic kidney cells (ATCC# CRL-1573) were propagated in EMEM tissue culture medium as described by ATCC in an atmosphere of 5% CO2 an...


US Patent US10266493 (2019)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM377589
PNG
(US10266493, Example 2III)
Show SMILES CC(C)(Sc1ccncc1-c1ccc(cc1F)C#N)C(O)=O
Show InChI InChI=1S/C16H13FN2O2S/c1-16(2,15(20)21)22-14-5-6-19-9-12(14)11-4-3-10(8-18)7-13(11)17/h3-7,9H,1-2H3,(H,20,21)
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n/an/an/an/a 26n/an/an/an/a



Ardea Biosciences, Inc.

US Patent


Assay Description
HEK293 human embryonic kidney cells (ATCC# CRL-1573) were propagated in EMEM tissue culture medium as described by ATCC in an atmosphere of 5% CO2 an...


US Patent US10266493 (2019)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM377553
PNG
(US10266493, Example 2PP)
Show SMILES CC(C)(Sc1ccncc1-c1ccncc1)C(O)=O
Show InChI InChI=1S/C14H14N2O2S/c1-14(2,13(17)18)19-12-5-8-16-9-11(12)10-3-6-15-7-4-10/h3-9H,1-2H3,(H,17,18)
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n/an/an/an/a 26n/an/an/an/a



Ardea Biosciences, Inc.

US Patent


Assay Description
HEK293 human embryonic kidney cells (ATCC# CRL-1573) were propagated in EMEM tissue culture medium as described by ATCC in an atmosphere of 5% CO2 an...


US Patent US10266493 (2019)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM377555
PNG
(US10266493, Example 2UU)
Show SMILES CC(C)(Sc1ccncc1-c1ccc(Br)cc1)C(O)=O
Show InChI InChI=1S/C15H14BrNO2S/c1-15(2,14(18)19)20-13-7-8-17-9-12(13)10-3-5-11(16)6-4-10/h3-9H,1-2H3,(H,18,19)
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n/an/an/an/a 26n/an/an/an/a



Ardea Biosciences, Inc.

US Patent


Assay Description
HEK293 human embryonic kidney cells (ATCC# CRL-1573) were propagated in EMEM tissue culture medium as described by ATCC in an atmosphere of 5% CO2 an...


US Patent US10266493 (2019)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM377561
PNG
(US10266493, Example 2AAA)
Show SMILES CC(C)(Sc1ccncc1-c1ccc(O)cc1)C(O)=O
Show InChI InChI=1S/C15H15NO3S/c1-15(2,14(18)19)20-13-7-8-16-9-12(13)10-3-5-11(17)6-4-10/h3-9,17H,1-2H3,(H,18,19)
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n/an/an/an/a 26n/an/an/an/a



Ardea Biosciences, Inc.

US Patent


Assay Description
HEK293 human embryonic kidney cells (ATCC# CRL-1573) were propagated in EMEM tissue culture medium as described by ATCC in an atmosphere of 5% CO2 an...


US Patent US10266493 (2019)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM377566
PNG
(US10266493, Example 2FFF)
Show SMILES CC(C)(Sc1ccncc1-c1ccc(C#N)c(Cl)c1)C(O)=O
Show InChI InChI=1S/C16H13ClN2O2S/c1-16(2,15(20)21)22-14-5-6-19-9-12(14)10-3-4-11(8-18)13(17)7-10/h3-7,9H,1-2H3,(H,20,21)
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n/an/an/an/a 26n/an/an/an/a



Ardea Biosciences, Inc.

US Patent


Assay Description
HEK293 human embryonic kidney cells (ATCC# CRL-1573) were propagated in EMEM tissue culture medium as described by ATCC in an atmosphere of 5% CO2 an...


US Patent US10266493 (2019)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM290431
PNG
(CAS No.:1352792-74-5 | RDEA3170 | US10100016, Veri...)
Show SMILES CC(C)(Sc1ccncc1-c1ccc(C#N)c2ccccc12)C(O)=O
Show InChI InChI=1S/C20H16N2O2S/c1-20(2,19(23)24)25-18-9-10-22-12-17(18)16-8-7-13(11-21)14-5-3-4-6-15(14)16/h3-10,12H,1-2H3,(H,23,24)
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n/an/an/an/a 26n/an/an/an/a



Ardea Biosciences, Inc.

US Patent


Assay Description
HEK293 human embryonic kidney cells (ATCC# CRL-1573) were propagated in EMEM tissue culture medium as described by ATCC in an atmosphere of 5% CO2 an...


US Patent US10266493 (2019)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM377552
PNG
(US10266493, Example 2NN)
Show SMILES Cc1cc(ccc1-c1cnccc1SC(C)(C)C(O)=O)C#N
Show InChI InChI=1S/C17H16N2O2S/c1-11-8-12(9-18)4-5-13(11)14-10-19-7-6-15(14)22-17(2,3)16(20)21/h4-8,10H,1-3H3,(H,20,21)
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n/an/an/an/a 26n/an/an/an/a



Ardea Biosciences, Inc.

US Patent


Assay Description
HEK293 human embryonic kidney cells (ATCC# CRL-1573) were propagated in EMEM tissue culture medium as described by ATCC in an atmosphere of 5% CO2 an...


US Patent US10266493 (2019)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM377516
PNG
(US10266493, Example 1A)
Show SMILES CC(C)(Sc1cccnc1-c1ccc(cc1)C#N)C(O)=O
Show InChI InChI=1S/C16H14N2O2S/c1-16(2,15(19)20)21-13-4-3-9-18-14(13)12-7-5-11(10-17)6-8-12/h3-9H,1-2H3,(H,19,20)
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n/an/an/an/a 275n/an/an/an/a



Ardea Biosciences, Inc.

US Patent


Assay Description
HEK293 human embryonic kidney cells (ATCC# CRL-1573) were propagated in EMEM tissue culture medium as described by ATCC in an atmosphere of 5% CO2 an...


US Patent US10266493 (2019)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM377522
PNG
(US10266493, Example 4C)
Show SMILES OC(=O)C1(CCC1)Sc1ncccc1-c1ccc(C#N)c2ccccc12
Show InChI InChI=1S/C21H16N2O2S/c22-13-14-8-9-17(16-6-2-1-5-15(14)16)18-7-3-12-23-19(18)26-21(20(24)25)10-4-11-21/h1-3,5-9,12H,4,10-11H2,(H,24,25)
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n/an/an/an/a 275n/an/an/an/a



Ardea Biosciences, Inc.

US Patent


Assay Description
HEK293 human embryonic kidney cells (ATCC# CRL-1573) were propagated in EMEM tissue culture medium as described by ATCC in an atmosphere of 5% CO2 an...


US Patent US10266493 (2019)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM377524
PNG
(US10266493, Example 2H)
Show SMILES CC(C)(Sc1ccncc1-c1cccc2ncccc12)C(O)=O
Show InChI InChI=1S/C18H16N2O2S/c1-18(2,17(21)22)23-16-8-10-19-11-14(16)12-5-3-7-15-13(12)6-4-9-20-15/h3-11H,1-2H3,(H,21,22)
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n/an/an/an/a 275n/an/an/an/a



Ardea Biosciences, Inc.

US Patent


Assay Description
HEK293 human embryonic kidney cells (ATCC# CRL-1573) were propagated in EMEM tissue culture medium as described by ATCC in an atmosphere of 5% CO2 an...


US Patent US10266493 (2019)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM377527
PNG
(US10266493, Example 2K)
Show SMILES CCc1ccc(cc1)-c1cnccc1SC(C)(C)C(O)=O
Show InChI InChI=1S/C17H19NO2S/c1-4-12-5-7-13(8-6-12)14-11-18-10-9-15(14)21-17(2,3)16(19)20/h5-11H,4H2,1-3H3,(H,19,20)
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n/an/an/an/a 275n/an/an/an/a



Ardea Biosciences, Inc.

US Patent


Assay Description
HEK293 human embryonic kidney cells (ATCC# CRL-1573) were propagated in EMEM tissue culture medium as described by ATCC in an atmosphere of 5% CO2 an...


US Patent US10266493 (2019)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM377529
PNG
(US10266493, Example 2N)
Show SMILES CC(C)(Sc1ccncc1-c1ccc(cc1)C(F)(F)F)C(O)=O
Show InChI InChI=1S/C16H14F3NO2S/c1-15(2,14(21)22)23-13-7-8-20-9-12(13)10-3-5-11(6-4-10)16(17,18)19/h3-9H,1-2H3,(H,21,22)
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n/an/an/an/a 275n/an/an/an/a



Ardea Biosciences, Inc.

US Patent


Assay Description
HEK293 human embryonic kidney cells (ATCC# CRL-1573) were propagated in EMEM tissue culture medium as described by ATCC in an atmosphere of 5% CO2 an...


US Patent US10266493 (2019)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM377532
PNG
(US10266493, Example 2Q)
Show SMILES CSc1ccc(cc1)-c1cnccc1SC(C)(C)C(O)=O
Show InChI InChI=1S/C16H17NO2S2/c1-16(2,15(18)19)21-14-8-9-17-10-13(14)11-4-6-12(20-3)7-5-11/h4-10H,1-3H3,(H,18,19)
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n/an/an/an/a 275n/an/an/an/a



Ardea Biosciences, Inc.

US Patent


Assay Description
HEK293 human embryonic kidney cells (ATCC# CRL-1573) were propagated in EMEM tissue culture medium as described by ATCC in an atmosphere of 5% CO2 an...


US Patent US10266493 (2019)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM377534
PNG
(US10266493, Example 2S)
Show SMILES CC(C)(Sc1ccncc1-c1ccc(Cl)c(Cl)c1)C(O)=O
Show InChI InChI=1S/C15H13Cl2NO2S/c1-15(2,14(19)20)21-13-5-6-18-8-10(13)9-3-4-11(16)12(17)7-9/h3-8H,1-2H3,(H,19,20)
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n/an/an/an/a 275n/an/an/an/a



Ardea Biosciences, Inc.

US Patent


Assay Description
HEK293 human embryonic kidney cells (ATCC# CRL-1573) were propagated in EMEM tissue culture medium as described by ATCC in an atmosphere of 5% CO2 an...


US Patent US10266493 (2019)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM377535
PNG
(US10266493, Example 2T)
Show SMILES COc1ccc(cn1)-c1cnccc1SC(C)(C)C(O)=O
Show InChI InChI=1S/C15H16N2O3S/c1-15(2,14(18)19)21-12-6-7-16-9-11(12)10-4-5-13(20-3)17-8-10/h4-9H,1-3H3,(H,18,19)
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n/an/an/an/a 275n/an/an/an/a



Ardea Biosciences, Inc.

US Patent


Assay Description
HEK293 human embryonic kidney cells (ATCC# CRL-1573) were propagated in EMEM tissue culture medium as described by ATCC in an atmosphere of 5% CO2 an...


US Patent US10266493 (2019)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM377536
PNG
(US10266493, Example 2U)
Show SMILES CC(C)(Sc1ccncc1-c1cncc2ccccc12)C(O)=O
Show InChI InChI=1S/C18H16N2O2S/c1-18(2,17(21)22)23-16-7-8-19-11-15(16)14-10-20-9-12-5-3-4-6-13(12)14/h3-11H,1-2H3,(H,21,22)
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n/an/an/an/a 275n/an/an/an/a



Ardea Biosciences, Inc.

US Patent


Assay Description
HEK293 human embryonic kidney cells (ATCC# CRL-1573) were propagated in EMEM tissue culture medium as described by ATCC in an atmosphere of 5% CO2 an...


US Patent US10266493 (2019)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM377540
PNG
(US10266493, Example 2BB)
Show SMILES Cc1ccc(-c2cnccc2SC(C)(C)C(O)=O)c2ccccc12
Show InChI InChI=1S/C20H19NO2S/c1-13-8-9-16(15-7-5-4-6-14(13)15)17-12-21-11-10-18(17)24-20(2,3)19(22)23/h4-12H,1-3H3,(H,22,23)
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n/an/an/an/a 275n/an/an/an/a



Ardea Biosciences, Inc.

US Patent


Assay Description
HEK293 human embryonic kidney cells (ATCC# CRL-1573) were propagated in EMEM tissue culture medium as described by ATCC in an atmosphere of 5% CO2 an...


US Patent US10266493 (2019)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM377541
PNG
(US10266493, Example 2CC)
Show SMILES CC(C)(Sc1ccncc1-c1ccc(cc1)S(N)(=O)=O)C(O)=O
Show InChI InChI=1S/C15H16N2O4S2/c1-15(2,14(18)19)22-13-7-8-17-9-12(13)10-3-5-11(6-4-10)23(16,20)21/h3-9H,1-2H3,(H,18,19)(H2,16,20,21)
KEGG

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n/an/an/an/a 275n/an/an/an/a



Ardea Biosciences, Inc.

US Patent


Assay Description
HEK293 human embryonic kidney cells (ATCC# CRL-1573) were propagated in EMEM tissue culture medium as described by ATCC in an atmosphere of 5% CO2 an...


US Patent US10266493 (2019)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM377542
PNG
(US10266493, Example 2DD)
Show SMILES CC(C)(Sc1ccncc1-c1cccc2ccccc12)C(O)=O
Show InChI InChI=1S/C19H17NO2S/c1-19(2,18(21)22)23-17-10-11-20-12-16(17)15-9-5-7-13-6-3-4-8-14(13)15/h3-12H,1-2H3,(H,21,22)
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n/an/an/an/a 275n/an/an/an/a



Ardea Biosciences, Inc.

US Patent


Assay Description
HEK293 human embryonic kidney cells (ATCC# CRL-1573) were propagated in EMEM tissue culture medium as described by ATCC in an atmosphere of 5% CO2 an...


US Patent US10266493 (2019)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM377543
PNG
(US10266493, Example 2EE)
Show SMILES CC(C)(Sc1ccncc1-c1ccc(Cl)c(c1)C(F)(F)F)C(O)=O
Show InChI InChI=1S/C16H13ClF3NO2S/c1-15(2,14(22)23)24-13-5-6-21-8-10(13)9-3-4-12(17)11(7-9)16(18,19)20/h3-8H,1-2H3,(H,22,23)
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n/an/an/an/a 275n/an/an/an/a



Ardea Biosciences, Inc.

US Patent


Assay Description
HEK293 human embryonic kidney cells (ATCC# CRL-1573) were propagated in EMEM tissue culture medium as described by ATCC in an atmosphere of 5% CO2 an...


US Patent US10266493 (2019)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM377545
PNG
(US10266493, Example 2GG)
Show SMILES CC(C)(Sc1ccncc1-c1ccc(F)cc1)C(O)=O
Show InChI InChI=1S/C15H14FNO2S/c1-15(2,14(18)19)20-13-7-8-17-9-12(13)10-3-5-11(16)6-4-10/h3-9H,1-2H3,(H,18,19)
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n/an/an/an/a 275n/an/an/an/a



Ardea Biosciences, Inc.

US Patent


Assay Description
HEK293 human embryonic kidney cells (ATCC# CRL-1573) were propagated in EMEM tissue culture medium as described by ATCC in an atmosphere of 5% CO2 an...


US Patent US10266493 (2019)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM377547
PNG
(US10266493, Example 2II)
Show SMILES CC(C)(Sc1ccncc1-c1ccnc2ccccc12)C(O)=O
Show InChI InChI=1S/C18H16N2O2S/c1-18(2,17(21)22)23-16-8-9-19-11-14(16)12-7-10-20-15-6-4-3-5-13(12)15/h3-11H,1-2H3,(H,21,22)
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n/an/an/an/a 275n/an/an/an/a



Ardea Biosciences, Inc.

US Patent


Assay Description
HEK293 human embryonic kidney cells (ATCC# CRL-1573) were propagated in EMEM tissue culture medium as described by ATCC in an atmosphere of 5% CO2 an...


US Patent US10266493 (2019)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM377549
PNG
(US10266493, Example 2KK)
Show SMILES CC(C)(Sc1ccncc1-c1ccc(cc1)C(N)=O)C(O)=O
Show InChI InChI=1S/C16H16N2O3S/c1-16(2,15(20)21)22-13-7-8-18-9-12(13)10-3-5-11(6-4-10)14(17)19/h3-9H,1-2H3,(H2,17,19)(H,20,21)
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n/an/an/an/a 275n/an/an/an/a



Ardea Biosciences, Inc.

US Patent


Assay Description
HEK293 human embryonic kidney cells (ATCC# CRL-1573) were propagated in EMEM tissue culture medium as described by ATCC in an atmosphere of 5% CO2 an...


US Patent US10266493 (2019)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM377551
PNG
(US10266493, Example 2MM)
Show SMILES COc1cncc(c1)-c1cnccc1SC(C)(C)C(O)=O
Show InChI InChI=1S/C15H16N2O3S/c1-15(2,14(18)19)21-13-4-5-16-9-12(13)10-6-11(20-3)8-17-7-10/h4-9H,1-3H3,(H,18,19)
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n/an/an/an/a 275n/an/an/an/a



Ardea Biosciences, Inc.

US Patent


Assay Description
HEK293 human embryonic kidney cells (ATCC# CRL-1573) were propagated in EMEM tissue culture medium as described by ATCC in an atmosphere of 5% CO2 an...


US Patent US10266493 (2019)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM377554
PNG
(US10266493, Example 2TT)
Show SMILES CC(C)(Sc1ccncc1-c1cccc(c1)C#N)C(O)=O
Show InChI InChI=1S/C16H14N2O2S/c1-16(2,15(19)20)21-14-6-7-18-10-13(14)12-5-3-4-11(8-12)9-17/h3-8,10H,1-2H3,(H,19,20)
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n/an/an/an/a 275n/an/an/an/a



Ardea Biosciences, Inc.

US Patent


Assay Description
HEK293 human embryonic kidney cells (ATCC# CRL-1573) were propagated in EMEM tissue culture medium as described by ATCC in an atmosphere of 5% CO2 an...


US Patent US10266493 (2019)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM377557
PNG
(US10266493, Example 2WW)
Show SMILES Cc1cc(ccc1-c1cnccc1SC(C)(C)C(O)=O)C(N)=O
Show InChI InChI=1S/C17H18N2O3S/c1-10-8-11(15(18)20)4-5-12(10)13-9-19-7-6-14(13)23-17(2,3)16(21)22/h4-9H,1-3H3,(H2,18,20)(H,21,22)
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n/an/an/an/a 275n/an/an/an/a



Ardea Biosciences, Inc.

US Patent


Assay Description
HEK293 human embryonic kidney cells (ATCC# CRL-1573) were propagated in EMEM tissue culture medium as described by ATCC in an atmosphere of 5% CO2 an...


US Patent US10266493 (2019)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM377558
PNG
(US10266493, Example 2XX)
Show SMILES COc1ccc(cc1)-c1cnccc1SC(C)(C)C(O)=O
Show InChI InChI=1S/C16H17NO3S/c1-16(2,15(18)19)21-14-8-9-17-10-13(14)11-4-6-12(20-3)7-5-11/h4-10H,1-3H3,(H,18,19)
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n/an/an/an/a 275n/an/an/an/a



Ardea Biosciences, Inc.

US Patent


Assay Description
HEK293 human embryonic kidney cells (ATCC# CRL-1573) were propagated in EMEM tissue culture medium as described by ATCC in an atmosphere of 5% CO2 an...


US Patent US10266493 (2019)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM377560
PNG
(US10266493, Example 2ZZ)
Show SMILES COc1cc(ccc1C#N)-c1cnccc1SC(C)(C)C(O)=O
Show InChI InChI=1S/C17H16N2O3S/c1-17(2,16(20)21)23-15-6-7-19-10-13(15)11-4-5-12(9-18)14(8-11)22-3/h4-8,10H,1-3H3,(H,20,21)
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n/an/an/an/a 275n/an/an/an/a



Ardea Biosciences, Inc.

US Patent


Assay Description
HEK293 human embryonic kidney cells (ATCC# CRL-1573) were propagated in EMEM tissue culture medium as described by ATCC in an atmosphere of 5% CO2 an...


US Patent US10266493 (2019)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM377562
PNG
(US10266493, Example 2BBB)
Show SMILES CC(C)(Sc1ccncc1-c1ccc(C#N)c(F)c1)C(O)=O
Show InChI InChI=1S/C16H13FN2O2S/c1-16(2,15(20)21)22-14-5-6-19-9-12(14)10-3-4-11(8-18)13(17)7-10/h3-7,9H,1-2H3,(H,20,21)
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n/an/an/an/a 275n/an/an/an/a



Ardea Biosciences, Inc.

US Patent


Assay Description
HEK293 human embryonic kidney cells (ATCC# CRL-1573) were propagated in EMEM tissue culture medium as described by ATCC in an atmosphere of 5% CO2 an...


US Patent US10266493 (2019)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM377563
PNG
(US10266493, Example 2CCC)
Show SMILES Cc1ccc(cc1)-c1cnccc1SC(C)(C)C(O)=O
Show InChI InChI=1S/C16H17NO2S/c1-11-4-6-12(7-5-11)13-10-17-9-8-14(13)20-16(2,3)15(18)19/h4-10H,1-3H3,(H,18,19)
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n/an/an/an/a 275n/an/an/an/a



Ardea Biosciences, Inc.

US Patent


Assay Description
HEK293 human embryonic kidney cells (ATCC# CRL-1573) were propagated in EMEM tissue culture medium as described by ATCC in an atmosphere of 5% CO2 an...


US Patent US10266493 (2019)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM377564
PNG
(US10266493, Example 2DDD)
Show SMILES CC(=O)Nc1ccc(cc1)-c1cnccc1SC(C)(C)C(O)=O
Show InChI InChI=1S/C17H18N2O3S/c1-11(20)19-13-6-4-12(5-7-13)14-10-18-9-8-15(14)23-17(2,3)16(21)22/h4-10H,1-3H3,(H,19,20)(H,21,22)
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n/an/an/an/a 275n/an/an/an/a



Ardea Biosciences, Inc.

US Patent


Assay Description
HEK293 human embryonic kidney cells (ATCC# CRL-1573) were propagated in EMEM tissue culture medium as described by ATCC in an atmosphere of 5% CO2 an...


US Patent US10266493 (2019)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM377565
PNG
(US10266493, Example 2EEE)
Show SMILES CC(C)(Sc1ccncc1-c1ccc(cc1)S(C)(=O)=O)C(O)=O
Show InChI InChI=1S/C16H17NO4S2/c1-16(2,15(18)19)22-14-8-9-17-10-13(14)11-4-6-12(7-5-11)23(3,20)21/h4-10H,1-3H3,(H,18,19)
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n/an/an/an/a 275n/an/an/an/a



Ardea Biosciences, Inc.

US Patent


Assay Description
HEK293 human embryonic kidney cells (ATCC# CRL-1573) were propagated in EMEM tissue culture medium as described by ATCC in an atmosphere of 5% CO2 an...


US Patent US10266493 (2019)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM377568
PNG
(US10266493, Example 4A)
Show SMILES CC(C)(Sc1ncccc1-c1ccc(C#N)c2ccccc12)C(O)=O
Show InChI InChI=1S/C20H16N2O2S/c1-20(2,19(23)24)25-18-17(8-5-11-22-18)16-10-9-13(12-21)14-6-3-4-7-15(14)16/h3-11H,1-2H3,(H,23,24)
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n/an/an/an/a 275n/an/an/an/a



Ardea Biosciences, Inc.

US Patent


Assay Description
HEK293 human embryonic kidney cells (ATCC# CRL-1573) were propagated in EMEM tissue culture medium as described by ATCC in an atmosphere of 5% CO2 an...


US Patent US10266493 (2019)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM377575
PNG
(US10266493, Example 2D)
Show SMILES CC(C)(Sc1ccncc1-c1ccc(cc1)S(=O)(=O)NC1CC1)C(O)=O
Show InChI InChI=1S/C18H20N2O4S2/c1-18(2,17(21)22)25-16-9-10-19-11-15(16)12-3-7-14(8-4-12)26(23,24)20-13-5-6-13/h3-4,7-11,13,20H,5-6H2,1-2H3,(H,21,22)
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n/an/an/an/a 275n/an/an/an/a



Ardea Biosciences, Inc.

US Patent


Assay Description
HEK293 human embryonic kidney cells (ATCC# CRL-1573) were propagated in EMEM tissue culture medium as described by ATCC in an atmosphere of 5% CO2 an...


US Patent US10266493 (2019)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM377577
PNG
(US10266493, Example 2F)
Show SMILES CC(C)(Sc1ccncc1-c1cnc2ccccc2c1)C(O)=O
Show InChI InChI=1S/C18H16N2O2S/c1-18(2,17(21)22)23-16-7-8-19-11-14(16)13-9-12-5-3-4-6-15(12)20-10-13/h3-11H,1-2H3,(H,21,22)
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n/an/an/an/a 275n/an/an/an/a



Ardea Biosciences, Inc.

US Patent


Assay Description
HEK293 human embryonic kidney cells (ATCC# CRL-1573) were propagated in EMEM tissue culture medium as described by ATCC in an atmosphere of 5% CO2 an...


US Patent US10266493 (2019)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM377580
PNG
(US10266493, Example 2W)
Show SMILES CC(C)(Sc1ccncc1-c1ccc(F)c(F)c1)C(O)=O
Show InChI InChI=1S/C15H13F2NO2S/c1-15(2,14(19)20)21-13-5-6-18-8-10(13)9-3-4-11(16)12(17)7-9/h3-8H,1-2H3,(H,19,20)
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n/an/an/an/a 275n/an/an/an/a



Ardea Biosciences, Inc.

US Patent


Assay Description
HEK293 human embryonic kidney cells (ATCC# CRL-1573) were propagated in EMEM tissue culture medium as described by ATCC in an atmosphere of 5% CO2 an...


US Patent US10266493 (2019)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM377582
PNG
(US10266493, Example 2AA)
Show SMILES CC(C)(Sc1ccncc1-c1ccc(Br)c2ccccc12)C(O)=O
Show InChI InChI=1S/C19H16BrNO2S/c1-19(2,18(22)23)24-17-9-10-21-11-15(17)13-7-8-16(20)14-6-4-3-5-12(13)14/h3-11H,1-2H3,(H,22,23)
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n/an/an/an/a 275n/an/an/an/a



Ardea Biosciences, Inc.

US Patent


Assay Description
HEK293 human embryonic kidney cells (ATCC# CRL-1573) were propagated in EMEM tissue culture medium as described by ATCC in an atmosphere of 5% CO2 an...


US Patent US10266493 (2019)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM377587
PNG
(US10266493, Example 2GGG)
Show SMILES CC(C)(Sc1ccncc1-c1ccc(S)cc1)C(O)=O
Show InChI InChI=1S/C15H15NO2S2/c1-15(2,14(17)18)20-13-7-8-16-9-12(13)10-3-5-11(19)6-4-10/h3-9,19H,1-2H3,(H,17,18)
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n/an/an/an/a 275n/an/an/an/a



Ardea Biosciences, Inc.

US Patent


Assay Description
HEK293 human embryonic kidney cells (ATCC# CRL-1573) were propagated in EMEM tissue culture medium as described by ATCC in an atmosphere of 5% CO2 an...


US Patent US10266493 (2019)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM377590
PNG
(US10266493, Example 2JJJ)
Show SMILES CC(C)(Sc1ccncc1-c1ccc(cc1F)C(N)=O)C(O)=O
Show InChI InChI=1S/C16H15FN2O3S/c1-16(2,15(21)22)23-13-5-6-19-8-11(13)10-4-3-9(14(18)20)7-12(10)17/h3-8H,1-2H3,(H2,18,20)(H,21,22)
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n/an/an/an/a 275n/an/an/an/a



Ardea Biosciences, Inc.

US Patent


Assay Description
HEK293 human embryonic kidney cells (ATCC# CRL-1573) were propagated in EMEM tissue culture medium as described by ATCC in an atmosphere of 5% CO2 an...


US Patent US10266493 (2019)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM377523
PNG
(US10266493, Example 6B)
Show SMILES CC(C)(Sc1ncncc1-c1ccc(C#N)c2ccccc12)C(O)=O
Show InChI InChI=1S/C19H15N3O2S/c1-19(2,18(23)24)25-17-16(10-21-11-22-17)15-8-7-12(9-20)13-5-3-4-6-14(13)15/h3-8,10-11H,1-2H3,(H,23,24)
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n/an/an/an/a 5.25E+3n/an/an/an/a



Ardea Biosciences, Inc.

US Patent


Assay Description
HEK293 human embryonic kidney cells (ATCC# CRL-1573) were propagated in EMEM tissue culture medium as described by ATCC in an atmosphere of 5% CO2 an...


US Patent US10266493 (2019)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM377588
PNG
(US10266493, Example 2HHH)
Show SMILES CC(C)(Sc1ccncc1-c1ccc(cc1F)C(O)=O)C(O)=O
Show InChI InChI=1S/C16H14FNO4S/c1-16(2,15(21)22)23-13-5-6-18-8-11(13)10-4-3-9(14(19)20)7-12(10)17/h3-8H,1-2H3,(H,19,20)(H,21,22)
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n/an/an/an/a 5.25E+3n/an/an/an/a



Ardea Biosciences, Inc.

US Patent


Assay Description
HEK293 human embryonic kidney cells (ATCC# CRL-1573) were propagated in EMEM tissue culture medium as described by ATCC in an atmosphere of 5% CO2 an...


US Patent US10266493 (2019)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM377528
PNG
(US10266493, Example 2M)
Show SMILES CC(C)(Sc1ccncc1-c1cccnc1)C(O)=O
Show InChI InChI=1S/C14H14N2O2S/c1-14(2,13(17)18)19-12-5-7-16-9-11(12)10-4-3-6-15-8-10/h3-9H,1-2H3,(H,17,18)
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n/an/an/an/a 5.25E+3n/an/an/an/a



Ardea Biosciences, Inc.

US Patent


Assay Description
HEK293 human embryonic kidney cells (ATCC# CRL-1573) were propagated in EMEM tissue culture medium as described by ATCC in an atmosphere of 5% CO2 an...


US Patent US10266493 (2019)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM377533
PNG
(US10266493, Example 2R)
Show SMILES CC(C)(Sc1ccncc1-c1ccccc1)C(O)=O
Show InChI InChI=1S/C15H15NO2S/c1-15(2,14(17)18)19-13-8-9-16-10-12(13)11-6-4-3-5-7-11/h3-10H,1-2H3,(H,17,18)
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n/an/an/an/a 5.25E+3n/an/an/an/a



Ardea Biosciences, Inc.

US Patent


Assay Description
HEK293 human embryonic kidney cells (ATCC# CRL-1573) were propagated in EMEM tissue culture medium as described by ATCC in an atmosphere of 5% CO2 an...


US Patent US10266493 (2019)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM377537
PNG
(US10266493, Example 2V)
Show SMILES COc1ccc2cc(ccc2c1)-c1cnccc1SC(C)(C)C(O)=O
Show InChI InChI=1S/C20H19NO3S/c1-20(2,19(22)23)25-18-8-9-21-12-17(18)15-5-4-14-11-16(24-3)7-6-13(14)10-15/h4-12H,1-3H3,(H,22,23)
KEGG

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n/an/an/an/a 5.25E+3n/an/an/an/a



Ardea Biosciences, Inc.

US Patent


Assay Description
HEK293 human embryonic kidney cells (ATCC# CRL-1573) were propagated in EMEM tissue culture medium as described by ATCC in an atmosphere of 5% CO2 an...


US Patent US10266493 (2019)

More data for this
Ligand-Target Pair
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