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Compile Data Set for Download or QSAR

Found 34 hits of kd for UniProtKB: P30874   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Somatostatin receptor type 2


(Homo sapiens (Human))
BDBM50065450
PNG
(2-Amino-3-phenyl-N-{4-[(2S,5S,8S,14S,17R)-8,10,14-...)
Show SMILES C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCNC(=O)[C@@H](N)Cc2ccccc2)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)CN(Cc2ccccc2)C(=O)[C@H](Cc2ccccc2)NC1=O
Show InChI InChI=1S/C57H65N9O8/c1-37(67)51-56(73)64-49(32-40-22-10-4-11-23-40)57(74)66(35-41-24-12-5-13-25-41)36-50(68)61-47(31-39-20-8-3-9-21-39)54(71)63-48(33-42-34-60-45-27-15-14-26-43(42)45)55(72)62-46(53(70)65-51)28-16-17-29-59-52(69)44(58)30-38-18-6-2-7-19-38/h2-15,18-27,34,37,44,46-49,51,60,67H,16-17,28-33,35-36,58H2,1H3,(H,59,69)(H,61,68)(H,62,72)(H,63,71)(H,64,73)(H,65,70)/t37-,44+,46+,47+,48-,49+,51+/m1/s1
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n/an/an/a 3n/an/an/an/an/a



University of California San Diego

Curated by ChEMBL


Assay Description
In vitro inhibition of radioligand binding to human somatostatin receptor (hsst2) expressed in CHO cells.


J Med Chem 41: 2679-85 (1998)


Article DOI: 10.1021/jm970393l
BindingDB Entry DOI: 10.7270/Q2Z60N6X
More data for this
Ligand-Target Pair
Somatostatin receptor type 2


(Homo sapiens (Human))
BDBM50473331
PNG
(CHEMBL420948)
Show SMILES C[C@@H](O)[C@@H](CC(=O)N[C@@H](CCCCN)CC(=O)N[C@H](CC(=O)N[C@H](CC(N)=O)Cc1ccccc1)Cc1c[nH]c2ccccc12)NC(C)=O
Show InChI InChI=1S/C36H51N7O6/c1-23(44)32(40-24(2)45)21-36(49)41-27(12-8-9-15-37)19-34(47)43-29(17-26-22-39-31-14-7-6-13-30(26)31)20-35(48)42-28(18-33(38)46)16-25-10-4-3-5-11-25/h3-7,10-11,13-14,22-23,27-29,32,39,44H,8-9,12,15-21,37H2,1-2H3,(H2,38,46)(H,40,45)(H,41,49)(H,42,48)(H,43,47)/t23-,27+,28+,29+,32-/m1/s1
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n/an/an/a<1.00E+5n/an/an/an/an/a



ETH Zurich

Curated by ChEMBL


Assay Description
Binding assay at human somatostatin receptor 2 (hsst2) expressed in CCL-39 cells using LTT-CST-14-(Tyr10) as radioligand.


J Med Chem 44: 2460-8 (2001)


Article DOI: 10.1021/jm010816q
BindingDB Entry DOI: 10.7270/Q2C53PKS
More data for this
Ligand-Target Pair
Somatostatin receptor type 2


(Homo sapiens (Human))
BDBM50065452
PNG
(2-Amino-N-{4-[(2S,5S,8S,14S,17R)-8,14-dibenzyl-5-(...)
Show SMILES C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCNC(=O)[C@@H](N)Cc2ccccc2)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)CN([C@@H](C)c2ccccc2)C(=O)[C@H](Cc2ccccc2)NC1=O
Show InChI InChI=1S/C58H67N9O8/c1-37(42-25-13-6-14-26-42)67-36-51(69)62-48(32-40-21-9-4-10-22-40)55(72)64-49(34-43-35-61-46-28-16-15-27-44(43)46)56(73)63-47(29-17-18-30-60-53(70)45(59)31-39-19-7-3-8-20-39)54(71)66-52(38(2)68)57(74)65-50(58(67)75)33-41-23-11-5-12-24-41/h3-16,19-28,35,37-38,45,47-50,52,61,68H,17-18,29-34,36,59H2,1-2H3,(H,60,70)(H,62,69)(H,63,73)(H,64,72)(H,65,74)(H,66,71)/t37-,38+,45-,47-,48-,49+,50-,52-/m0/s1
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n/an/an/a 6.20n/an/an/an/an/a



University of California San Diego

Curated by ChEMBL


Assay Description
In vitro inhibition of radioligand binding to human somatostatin receptor (hsst2) expressed in CHO cells.


J Med Chem 41: 2679-85 (1998)


Article DOI: 10.1021/jm970393l
BindingDB Entry DOI: 10.7270/Q2Z60N6X
More data for this
Ligand-Target Pair
Somatostatin receptor type 2


(Homo sapiens (Human))
BDBM50065451
PNG
(2-Amino-N-{4-[(2S,5S,8S,14S,17R)-8,14-dibenzyl-5-(...)
Show SMILES C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCNC(=O)[C@@H](N)Cc2ccccc2)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)CN([C@H](C)c2ccccc2)C(=O)[C@H](Cc2ccccc2)NC1=O
Show InChI InChI=1S/C58H67N9O8/c1-37(42-25-13-6-14-26-42)67-36-51(69)62-48(32-40-21-9-4-10-22-40)55(72)64-49(34-43-35-61-46-28-16-15-27-44(43)46)56(73)63-47(29-17-18-30-60-53(70)45(59)31-39-19-7-3-8-20-39)54(71)66-52(38(2)68)57(74)65-50(58(67)75)33-41-23-11-5-12-24-41/h3-16,19-28,35,37-38,45,47-50,52,61,68H,17-18,29-34,36,59H2,1-2H3,(H,60,70)(H,62,69)(H,63,73)(H,64,72)(H,65,74)(H,66,71)/t37-,38-,45+,47+,48+,49-,50+,52+/m1/s1
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n/an/an/a 2n/an/an/an/an/a



University of California San Diego

Curated by ChEMBL


Assay Description
In vitro inhibition of radioligand binding to human somatostatin receptor (hsst2) expressed in CHO cells.


J Med Chem 41: 2679-85 (1998)


Article DOI: 10.1021/jm970393l
BindingDB Entry DOI: 10.7270/Q2Z60N6X
More data for this
Ligand-Target Pair
Somatostatin receptor type 2


(Homo sapiens (Human))
BDBM50098603
PNG
(10-(4-Amino-butyl)-19-[(2-amino-3-phenyl-propionyl...)
Show SMILES C[C@@H](O)[C@H](NC(=O)[C@@H]1CSSC[C@@H](N(C)C(=O)[C@H](N)Cc2ccccc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1)C(N)=O
Show InChI InChI=1S/C50H67N11O10S2/c1-28(62)41(43(53)64)59-47(68)39-26-72-73-27-40(61(3)50(71)34(52)22-30-14-6-4-7-15-30)48(69)57-37(23-31-16-8-5-9-17-31)45(66)56-38(24-32-25-54-35-19-11-10-18-33(32)35)46(67)55-36(20-12-13-21-51)44(65)60-42(29(2)63)49(70)58-39/h4-11,14-19,25,28-29,34,36-42,54,62-63H,12-13,20-24,26-27,51-52H2,1-3H3,(H2,53,64)(H,55,67)(H,56,66)(H,57,69)(H,58,70)(H,59,68)(H,60,65)/t28-,29-,34-,36+,37+,38+,39+,40-,41+,42+/m1/s1
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n/an/an/a 1.04n/an/an/an/an/a



Tulane University Health Sciences Center

Curated by ChEMBL


Assay Description
Binding affinity was determined on cloned human somatostatin receptor-1 (hsst2)


J Med Chem 44: 1416-21 (2001)


Article DOI: 10.1021/jm000361p
BindingDB Entry DOI: 10.7270/Q2M044QS
More data for this
Ligand-Target Pair
Somatostatin receptor type 2


(Homo sapiens (Human))
BDBM50098610
PNG
(10-(4-Amino-butyl)-19-[2-amino-3-(4-hydroxy-phenyl...)
Show SMILES C[C@@H](O)[C@H](NC(=O)[C@@H]1CSSC[C@@H](NC(=O)[C@H](N)Cc2ccc(O)cc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1C)C(N)=O
Show InChI InChI=1S/C50H67N11O11S2/c1-27(62)41(43(53)65)59-49(71)40-26-74-73-25-39(58-44(66)34(52)21-30-16-18-32(64)19-17-30)48(70)56-37(22-29-11-5-4-6-12-29)46(68)57-38(23-31-24-54-35-14-8-7-13-33(31)35)47(69)55-36(15-9-10-20-51)45(67)60-42(28(2)63)50(72)61(40)3/h4-8,11-14,16-19,24,27-28,34,36-42,54,62-64H,9-10,15,20-23,25-26,51-52H2,1-3H3,(H2,53,65)(H,55,69)(H,56,70)(H,57,68)(H,58,66)(H,59,71)(H,60,67)/t27-,28-,34-,36+,37+,38+,39-,40+,41+,42+/m1/s1
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n/an/an/a 56.2n/an/an/an/an/a



Tulane University Health Sciences Center

Curated by ChEMBL


Assay Description
Binding affinity was determined on cloned human somatostatin receptor-1 (hsst2)


J Med Chem 44: 1416-21 (2001)


Article DOI: 10.1021/jm000361p
BindingDB Entry DOI: 10.7270/Q2M044QS
More data for this
Ligand-Target Pair
Somatostatin receptor type 2


(Homo sapiens (Human))
BDBM50098611
PNG
(10-(4-Amino-butyl)-19-[2-amino-3-(4-hydroxy-phenyl...)
Show SMILES C[C@@H](O)[C@H](NC(=O)[C@@H]1CSSC[C@@H](NC(=O)[C@H](N)Cc2ccc(O)cc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N(C)[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1)C(N)=O
Show InChI InChI=1S/C50H67N11O11S2/c1-27(62)41(43(53)65)59-47(69)39-26-74-73-25-38(57-44(66)34(52)21-30-16-18-32(64)19-17-30)46(68)56-37(22-29-11-5-4-6-12-29)50(72)61(3)40(23-31-24-54-35-14-8-7-13-33(31)35)48(70)55-36(15-9-10-20-51)45(67)60-42(28(2)63)49(71)58-39/h4-8,11-14,16-19,24,27-28,34,36-42,54,62-64H,9-10,15,20-23,25-26,51-52H2,1-3H3,(H2,53,65)(H,55,70)(H,56,68)(H,57,66)(H,58,71)(H,59,69)(H,60,67)/t27-,28-,34-,36+,37+,38-,39+,40+,41+,42+/m1/s1
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n/an/an/a 120n/an/an/an/an/a



Tulane University Health Sciences Center

Curated by ChEMBL


Assay Description
Binding affinity was determined on cloned human somatostatin receptor-1 (hsst2)


J Med Chem 44: 1416-21 (2001)


Article DOI: 10.1021/jm000361p
BindingDB Entry DOI: 10.7270/Q2M044QS
More data for this
Ligand-Target Pair
Somatostatin receptor type 2


(Homo sapiens (Human))
BDBM50098613
PNG
(10-(4-Amino-butyl)-16-benzyl-7-(1-hydroxy-ethyl)-1...)
Show SMILES CN[C@H](Cc1ccc(O)cc1)C(=O)N[C@@H]1CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC1=O)[C@@H](C)O)C(=O)N[C@@H]([C@@H](C)O)C(N)=O
Show InChI InChI=1S/C50H67N11O11S2/c1-27(62)41(43(52)65)60-49(71)40-26-74-73-25-39(58-45(67)36(53-3)21-30-16-18-32(64)19-17-30)48(70)56-37(22-29-11-5-4-6-12-29)46(68)57-38(23-31-24-54-34-14-8-7-13-33(31)34)47(69)55-35(15-9-10-20-51)44(66)61-42(28(2)63)50(72)59-40/h4-8,11-14,16-19,24,27-28,35-42,53-54,62-64H,9-10,15,20-23,25-26,51H2,1-3H3,(H2,52,65)(H,55,69)(H,56,70)(H,57,68)(H,58,67)(H,59,72)(H,60,71)(H,61,66)/t27-,28-,35+,36-,37+,38+,39-,40+,41+,42+/m1/s1
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n/an/an/a 9.74n/an/an/an/an/a



Tulane University Health Sciences Center

Curated by ChEMBL


Assay Description
Binding affinity was determined on cloned human somatostatin receptor-1 (hsst2)


J Med Chem 44: 1416-21 (2001)


Article DOI: 10.1021/jm000361p
BindingDB Entry DOI: 10.7270/Q2M044QS
More data for this
Ligand-Target Pair
Somatostatin receptor type 2


(Homo sapiens (Human))
BDBM50098616
PNG
(10-(4-Amino-butyl)-19-(2-amino-3-phenyl-propionyla...)
Show SMILES C[C@@H](O)[C@H](NC(=O)[C@@H]1CSSC[C@@H](NC(=O)[C@H](N)Cc2ccccc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N(C)[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1)C(N)=O
Show InChI InChI=1S/C50H67N11O10S2/c1-28(62)41(43(53)64)59-47(68)39-27-73-72-26-38(57-44(65)34(52)22-30-14-6-4-7-15-30)46(67)55-36(23-31-16-8-5-9-17-31)45(66)56-37(24-32-25-54-35-19-11-10-18-33(32)35)50(71)61(3)40(20-12-13-21-51)48(69)60-42(29(2)63)49(70)58-39/h4-11,14-19,25,28-29,34,36-42,54,62-63H,12-13,20-24,26-27,51-52H2,1-3H3,(H2,53,64)(H,55,67)(H,56,66)(H,57,65)(H,58,70)(H,59,68)(H,60,69)/t28-,29-,34-,36+,37+,38-,39+,40+,41+,42+/m1/s1
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n/an/an/a 1.84n/an/an/an/an/a



Tulane University Health Sciences Center

Curated by ChEMBL


Assay Description
Binding affinity was determined on cloned human somatostatin receptor-1 (hsst2)


J Med Chem 44: 1416-21 (2001)


Article DOI: 10.1021/jm000361p
BindingDB Entry DOI: 10.7270/Q2M044QS
More data for this
Ligand-Target Pair
Somatostatin receptor type 2


(Homo sapiens (Human))
BDBM50098608
PNG
(10-(4-Amino-butyl)-19-(2-amino-3-phenyl-propionyla...)
Show SMILES C[C@@H](O)[C@H](NC(=O)[C@@H]1CSSC[C@@H](NC(=O)[C@H](N)Cc2ccccc2)C(=O)N(C)[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1)C(N)=O
Show InChI InChI=1S/C50H67N11O10S2/c1-28(62)41(43(53)64)59-47(68)38-26-72-73-27-39(58-44(65)34(52)22-30-14-6-4-7-15-30)50(71)61(3)40(23-31-16-8-5-9-17-31)48(69)56-37(24-32-25-54-35-19-11-10-18-33(32)35)46(67)55-36(20-12-13-21-51)45(66)60-42(29(2)63)49(70)57-38/h4-11,14-19,25,28-29,34,36-42,54,62-63H,12-13,20-24,26-27,51-52H2,1-3H3,(H2,53,64)(H,55,67)(H,56,69)(H,57,70)(H,58,65)(H,59,68)(H,60,66)/t28-,29-,34-,36+,37+,38+,39-,40+,41+,42+/m1/s1
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n/an/an/a 13.2n/an/an/an/an/a



Tulane University Health Sciences Center

Curated by ChEMBL


Assay Description
Binding affinity was determined on cloned human somatostatin receptor-1 (hsst2)


J Med Chem 44: 1416-21 (2001)


Article DOI: 10.1021/jm000361p
BindingDB Entry DOI: 10.7270/Q2M044QS
More data for this
Ligand-Target Pair
Somatostatin receptor type 2


(Homo sapiens (Human))
BDBM50098607
PNG
(10-(4-Amino-butyl)-19-[2-amino-3-(4-hydroxy-phenyl...)
Show SMILES C[C@@H](O)[C@H](NC(=O)[C@@H]1CSSC[C@@H](NC(=O)[C@H](N)Cc2ccc(O)cc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N(C)[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1)C(N)=O
Show InChI InChI=1S/C50H67N11O11S2/c1-27(62)41(43(53)65)59-47(69)39-26-74-73-25-38(57-44(66)34(52)21-30-16-18-32(64)19-17-30)46(68)55-36(22-29-11-5-4-6-12-29)45(67)56-37(23-31-24-54-35-14-8-7-13-33(31)35)50(72)61(3)40(15-9-10-20-51)48(70)60-42(28(2)63)49(71)58-39/h4-8,11-14,16-19,24,27-28,34,36-42,54,62-64H,9-10,15,20-23,25-26,51-52H2,1-3H3,(H2,53,65)(H,55,68)(H,56,67)(H,57,66)(H,58,71)(H,59,69)(H,60,70)/t27-,28-,34-,36+,37+,38-,39+,40+,41+,42+/m1/s1
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n/an/an/a 14.3n/an/an/an/an/a



Tulane University Health Sciences Center

Curated by ChEMBL


Assay Description
Binding affinity was determined on cloned human somatostatin receptor-1 (hsst2)


J Med Chem 44: 1416-21 (2001)


Article DOI: 10.1021/jm000361p
BindingDB Entry DOI: 10.7270/Q2M044QS
More data for this
Ligand-Target Pair
Somatostatin receptor type 2


(Homo sapiens (Human))
BDBM50098619
PNG
(10-(4-Amino-butyl)-19-(2-amino-3-phenyl-propionyla...)
Show SMILES C[C@@H](O)[C@H](NC(=O)[C@@H]1CSSC[C@@H](NC(=O)[C@H](N)Cc2ccccc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1)C(N)=O
Show InChI InChI=1S/C49H65N11O10S2/c1-27(61)40(42(52)63)59-48(69)39-26-72-71-25-38(57-43(64)33(51)21-29-13-5-3-6-14-29)47(68)55-36(22-30-15-7-4-8-16-30)45(66)56-37(23-31-24-53-34-18-10-9-17-32(31)34)46(67)54-35(19-11-12-20-50)44(65)60-41(28(2)62)49(70)58-39/h3-10,13-18,24,27-28,33,35-41,53,61-62H,11-12,19-23,25-26,50-51H2,1-2H3,(H2,52,63)(H,54,67)(H,55,68)(H,56,66)(H,57,64)(H,58,70)(H,59,69)(H,60,65)/t27-,28-,33-,35+,36+,37+,38-,39+,40+,41+/m1/s1
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n/an/an/a 0.150n/an/an/an/an/a



Tulane University Health Sciences Center

Curated by ChEMBL


Assay Description
Binding affinity was determined on cloned human somatostatin receptor-1 (hsst2)


J Med Chem 44: 1416-21 (2001)


Article DOI: 10.1021/jm000361p
BindingDB Entry DOI: 10.7270/Q2M044QS
More data for this
Ligand-Target Pair
Somatostatin receptor type 2


(Homo sapiens (Human))
BDBM50098606
PNG
(10-(4-Amino-butyl)-19-[2-amino-3-(4-hydroxy-phenyl...)
Show SMILES C[C@@H](O)[C@H](NC(=O)[C@@H]1CSSC[C@@H](NC(=O)[C@H](N)Cc2ccc(O)cc2)C(=O)N(C)[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1)C(N)=O
Show InChI InChI=1S/C50H67N11O11S2/c1-27(62)41(43(53)65)59-47(69)38-25-73-74-26-39(58-44(66)34(52)21-30-16-18-32(64)19-17-30)50(72)61(3)40(22-29-11-5-4-6-12-29)48(70)56-37(23-31-24-54-35-14-8-7-13-33(31)35)46(68)55-36(15-9-10-20-51)45(67)60-42(28(2)63)49(71)57-38/h4-8,11-14,16-19,24,27-28,34,36-42,54,62-64H,9-10,15,20-23,25-26,51-52H2,1-3H3,(H2,53,65)(H,55,68)(H,56,70)(H,57,71)(H,58,66)(H,59,69)(H,60,67)/t27-,28-,34-,36+,37+,38+,39-,40+,41+,42+/m1/s1
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n/an/an/a 40.1n/an/an/an/an/a



Tulane University Health Sciences Center

Curated by ChEMBL


Assay Description
Binding affinity was determined on cloned human somatostatin receptor-1 (hsst2)


J Med Chem 44: 1416-21 (2001)


Article DOI: 10.1021/jm000361p
BindingDB Entry DOI: 10.7270/Q2M044QS
More data for this
Ligand-Target Pair
Somatostatin receptor type 2


(Homo sapiens (Human))
BDBM50098602
PNG
(10-(4-Amino-butyl)-19-(2-amino-3-phenyl-propionyla...)
Show SMILES C[C@@H](O)[C@H](NC(=O)[C@@H]1CSSC[C@@H](NC(=O)[C@H](N)Cc2ccccc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N(C)[C@@H]([C@@H](C)O)C(=O)N1)C(N)=O
Show InChI InChI=1S/C50H67N11O10S2/c1-28(62)41(43(53)64)60-48(69)40-27-73-72-26-39(58-44(65)34(52)22-30-14-6-4-7-15-30)47(68)56-37(23-31-16-8-5-9-17-31)45(66)57-38(24-32-25-54-35-19-11-10-18-33(32)35)46(67)55-36(20-12-13-21-51)50(71)61(3)42(29(2)63)49(70)59-40/h4-11,14-19,25,28-29,34,36-42,54,62-63H,12-13,20-24,26-27,51-52H2,1-3H3,(H2,53,64)(H,55,67)(H,56,68)(H,57,66)(H,58,65)(H,59,70)(H,60,69)/t28-,29-,34-,36+,37+,38+,39-,40+,41+,42+/m1/s1
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n/an/an/a>1.00E+3n/an/an/an/an/a



Tulane University Health Sciences Center

Curated by ChEMBL


Assay Description
Binding affinity was determined on cloned human somatostatin receptor-1 (hsst2)


J Med Chem 44: 1416-21 (2001)


Article DOI: 10.1021/jm000361p
BindingDB Entry DOI: 10.7270/Q2M044QS
More data for this
Ligand-Target Pair
Somatostatin receptor type 2


(Homo sapiens (Human))
BDBM50098605
PNG
(10-(4-Amino-butyl)-19-[2-amino-3-(4-hydroxy-phenyl...)
Show SMILES C[C@@H](O)[C@H](NC(=O)[C@@H]1CSSC[C@@H](NC(=O)[C@H](N)Cc2ccc(O)cc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N(C)[C@@H]([C@@H](C)O)C(=O)N1)C(N)=O
Show InChI InChI=1S/C50H67N11O11S2/c1-27(62)41(43(53)65)60-48(70)40-26-74-73-25-39(58-44(66)34(52)21-30-16-18-32(64)19-17-30)47(69)56-37(22-29-11-5-4-6-12-29)45(67)57-38(23-31-24-54-35-14-8-7-13-33(31)35)46(68)55-36(15-9-10-20-51)50(72)61(3)42(28(2)63)49(71)59-40/h4-8,11-14,16-19,24,27-28,34,36-42,54,62-64H,9-10,15,20-23,25-26,51-52H2,1-3H3,(H2,53,65)(H,55,68)(H,56,69)(H,57,67)(H,58,66)(H,59,71)(H,60,70)/t27-,28-,34-,36+,37+,38+,39-,40+,41+,42+/m1/s1
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n/an/an/a 61.4n/an/an/an/an/a



Tulane University Health Sciences Center

Curated by ChEMBL


Assay Description
Binding affinity was determined on cloned human somatostatin receptor-1 (hsst2)


J Med Chem 44: 1416-21 (2001)


Article DOI: 10.1021/jm000361p
BindingDB Entry DOI: 10.7270/Q2M044QS
More data for this
Ligand-Target Pair
Somatostatin receptor type 2


(Homo sapiens (Human))
BDBM50098618
PNG
(10-(4-Amino-butyl)-19-[2-amino-3-(4-hydroxy-phenyl...)
Show SMILES C[C@@H](O)[C@H](NC(=O)[C@@H]1CSSC[C@@H](NC(=O)[C@H](N)Cc2ccc(O)cc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1)C(N)=O
Show InChI InChI=1S/C49H65N11O11S2/c1-26(61)40(42(52)64)59-48(70)39-25-73-72-24-38(57-43(65)33(51)20-29-15-17-31(63)18-16-29)47(69)55-36(21-28-10-4-3-5-11-28)45(67)56-37(22-30-23-53-34-13-7-6-12-32(30)34)46(68)54-35(14-8-9-19-50)44(66)60-41(27(2)62)49(71)58-39/h3-7,10-13,15-18,23,26-27,33,35-41,53,61-63H,8-9,14,19-22,24-25,50-51H2,1-2H3,(H2,52,64)(H,54,68)(H,55,69)(H,56,67)(H,57,65)(H,58,71)(H,59,70)(H,60,66)/t26-,27-,33-,35+,36+,37+,38-,39+,40+,41+/m1/s1
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n/an/an/a 10.3n/an/an/an/an/a



Tulane University Health Sciences Center

Curated by ChEMBL


Assay Description
Binding affinity was determined on cloned human somatostatin receptor-1 (hsst2)


J Med Chem 44: 1416-21 (2001)


Article DOI: 10.1021/jm000361p
BindingDB Entry DOI: 10.7270/Q2M044QS
More data for this
Ligand-Target Pair
Somatostatin receptor type 2


(Homo sapiens (Human))
BDBM50098609
PNG
(10-(4-Amino-butyl)-19-(2-amino-3-phenyl-propionyla...)
Show SMILES C[C@@H](O)[C@H](N(C)C(=O)[C@@H]1CSSC[C@@H](NC(=O)[C@H](N)Cc2ccccc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1)C(N)=O
Show InChI InChI=1S/C50H67N11O10S2/c1-28(62)41-49(70)59-40(50(71)61(3)42(29(2)63)43(53)64)27-73-72-26-39(58-44(65)34(52)22-30-14-6-4-7-15-30)48(69)56-37(23-31-16-8-5-9-17-31)46(67)57-38(24-32-25-54-35-19-11-10-18-33(32)35)47(68)55-36(45(66)60-41)20-12-13-21-51/h4-11,14-19,25,28-29,34,36-42,54,62-63H,12-13,20-24,26-27,51-52H2,1-3H3,(H2,53,64)(H,55,68)(H,56,69)(H,57,67)(H,58,65)(H,59,70)(H,60,66)/t28-,29-,34-,36+,37+,38+,39-,40+,41+,42+/m1/s1
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n/an/an/a 14.8n/an/an/an/an/a



Tulane University Health Sciences Center

Curated by ChEMBL


Assay Description
Binding affinity was determined on cloned human somatostatin receptor-1 (hsst2)


J Med Chem 44: 1416-21 (2001)


Article DOI: 10.1021/jm000361p
BindingDB Entry DOI: 10.7270/Q2M044QS
More data for this
Ligand-Target Pair
Somatostatin receptor type 2


(Homo sapiens (Human))
BDBM50098604
PNG
(10-(4-Amino-butyl)-19-[2-amino-3-(4-hydroxy-phenyl...)
Show SMILES C[C@@H](O)[C@H](NC(=O)[C@@H]1CSSC[C@@H](N(C)C(=O)[C@H](N)Cc2ccc(O)cc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1)C(N)=O
Show InChI InChI=1S/C50H67N11O11S2/c1-27(62)41(43(53)65)59-47(69)39-25-73-74-26-40(61(3)50(72)34(52)21-30-16-18-32(64)19-17-30)48(70)57-37(22-29-11-5-4-6-12-29)45(67)56-38(23-31-24-54-35-14-8-7-13-33(31)35)46(68)55-36(15-9-10-20-51)44(66)60-42(28(2)63)49(71)58-39/h4-8,11-14,16-19,24,27-28,34,36-42,54,62-64H,9-10,15,20-23,25-26,51-52H2,1-3H3,(H2,53,65)(H,55,68)(H,56,67)(H,57,70)(H,58,71)(H,59,69)(H,60,66)/t27-,28-,34-,36+,37+,38+,39+,40-,41+,42+/m1/s1
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n/an/an/a 8.96n/an/an/an/an/a



Tulane University Health Sciences Center

Curated by ChEMBL


Assay Description
Binding affinity was determined on cloned human somatostatin receptor-1 (hsst2)


J Med Chem 44: 1416-21 (2001)


Article DOI: 10.1021/jm000361p
BindingDB Entry DOI: 10.7270/Q2M044QS
More data for this
Ligand-Target Pair
Somatostatin receptor type 2


(Homo sapiens (Human))
BDBM50098614
PNG
(10-(4-Amino-butyl)-19-(2-amino-3-phenyl-propionyla...)
Show SMILES C[C@@H](O)[C@H](NC(=O)[C@@H]1CSSC[C@@H](NC(=O)[C@H](N)Cc2ccccc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1C)C(N)=O
Show InChI InChI=1S/C50H67N11O10S2/c1-28(62)41(43(53)64)59-49(70)40-27-73-72-26-39(58-44(65)34(52)22-30-14-6-4-7-15-30)48(69)56-37(23-31-16-8-5-9-17-31)46(67)57-38(24-32-25-54-35-19-11-10-18-33(32)35)47(68)55-36(20-12-13-21-51)45(66)60-42(29(2)63)50(71)61(40)3/h4-11,14-19,25,28-29,34,36-42,54,62-63H,12-13,20-24,26-27,51-52H2,1-3H3,(H2,53,64)(H,55,68)(H,56,69)(H,57,67)(H,58,65)(H,59,70)(H,60,66)/t28-,29-,34-,36+,37+,38+,39-,40+,41+,42+/m1/s1
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n/an/an/a 56.2n/an/an/an/an/a



Tulane University Health Sciences Center

Curated by ChEMBL


Assay Description
Binding affinity was determined on cloned human somatostatin receptor-1 (hsst2)


J Med Chem 44: 1416-21 (2001)


Article DOI: 10.1021/jm000361p
BindingDB Entry DOI: 10.7270/Q2M044QS
More data for this
Ligand-Target Pair
Somatostatin receptor type 2


(Homo sapiens (Human))
BDBM50098612
PNG
(10-(4-Amino-butyl)-16-benzyl-7-(1-hydroxy-ethyl)-1...)
Show SMILES CN[C@H](Cc1ccccc1)C(=O)N[C@@H]1CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC1=O)[C@@H](C)O)C(=O)N[C@@H]([C@@H](C)O)C(N)=O
Show InChI InChI=1S/C50H67N11O10S2/c1-28(62)41(43(52)64)60-49(70)40-27-73-72-26-39(58-45(66)36(53-3)22-30-14-6-4-7-15-30)48(69)56-37(23-31-16-8-5-9-17-31)46(67)57-38(24-32-25-54-34-19-11-10-18-33(32)34)47(68)55-35(20-12-13-21-51)44(65)61-42(29(2)63)50(71)59-40/h4-11,14-19,25,28-29,35-42,53-54,62-63H,12-13,20-24,26-27,51H2,1-3H3,(H2,52,64)(H,55,68)(H,56,69)(H,57,67)(H,58,66)(H,59,71)(H,60,70)(H,61,65)/t28-,29-,35+,36-,37+,38+,39-,40+,41+,42+/m1/s1
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n/an/an/a 1.03n/an/an/an/an/a



Tulane University Health Sciences Center

Curated by ChEMBL


Assay Description
Binding affinity was determined on cloned human somatostatin receptor-1 (hsst2)


J Med Chem 44: 1416-21 (2001)


Article DOI: 10.1021/jm000361p
BindingDB Entry DOI: 10.7270/Q2M044QS
More data for this
Ligand-Target Pair
Somatostatin receptor type 2


(Homo sapiens (Human))
BDBM50098617
PNG
(10-(4-Amino-butyl)-19-[2-amino-3-(4-hydroxy-phenyl...)
Show SMILES C[C@@H](O)[C@H](N(C)C(=O)[C@@H]1CSSC[C@@H](NC(=O)[C@H](N)Cc2ccc(O)cc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1)C(N)=O
Show InChI InChI=1S/C50H67N11O11S2/c1-27(62)41-49(71)59-40(50(72)61(3)42(28(2)63)43(53)65)26-74-73-25-39(58-44(66)34(52)21-30-16-18-32(64)19-17-30)48(70)56-37(22-29-11-5-4-6-12-29)46(68)57-38(23-31-24-54-35-14-8-7-13-33(31)35)47(69)55-36(45(67)60-41)15-9-10-20-51/h4-8,11-14,16-19,24,27-28,34,36-42,54,62-64H,9-10,15,20-23,25-26,51-52H2,1-3H3,(H2,53,65)(H,55,69)(H,56,70)(H,57,68)(H,58,66)(H,59,71)(H,60,67)/t27-,28-,34-,36+,37+,38+,39-,40+,41+,42+/m1/s1
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n/an/an/a 26.2n/an/an/an/an/a



Tulane University Health Sciences Center

Curated by ChEMBL


Assay Description
Binding affinity was determined on cloned human somatostatin receptor-1 (hsst2)


J Med Chem 44: 1416-21 (2001)


Article DOI: 10.1021/jm000361p
BindingDB Entry DOI: 10.7270/Q2M044QS
More data for this
Ligand-Target Pair
Somatostatin receptor type 2


(Homo sapiens (Human))
BDBM50098615
PNG
(10-(4-Amino-butyl)-19-(2-amino-3-phenyl-propionyla...)
Show SMILES C[C@@H](O)[C@H](NC(=O)[C@@H]1CSSC[C@@H](NC(=O)[C@H](N)Cc2ccccc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N(C)[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1)C(N)=O
Show InChI InChI=1S/C50H67N11O10S2/c1-28(62)41(43(53)64)59-47(68)39-27-73-72-26-38(57-44(65)34(52)22-30-14-6-4-7-15-30)46(67)56-37(23-31-16-8-5-9-17-31)50(71)61(3)40(24-32-25-54-35-19-11-10-18-33(32)35)48(69)55-36(20-12-13-21-51)45(66)60-42(29(2)63)49(70)58-39/h4-11,14-19,25,28-29,34,36-42,54,62-63H,12-13,20-24,26-27,51-52H2,1-3H3,(H2,53,64)(H,55,69)(H,56,67)(H,57,65)(H,58,70)(H,59,68)(H,60,66)/t28-,29-,34-,36+,37+,38-,39+,40+,41+,42+/m1/s1
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n/an/an/a 23.5n/an/an/an/an/a



Tulane University Health Sciences Center

Curated by ChEMBL


Assay Description
Binding affinity was determined on cloned human somatostatin receptor-1 (hsst2)


J Med Chem 44: 1416-21 (2001)


Article DOI: 10.1021/jm000361p
BindingDB Entry DOI: 10.7270/Q2M044QS
More data for this
Ligand-Target Pair
Somatostatin receptor type 2


(Homo sapiens (Human))
BDBM50192018
PNG
(CHEMBL3350037)
Show SMILES C[C@@H](O)[C@H](CO)NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@H](N)Cc2ccccc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1
Show InChI InChI=1S/C49H66N10O10S2/c1-28(61)39(25-60)56-48(68)41-27-71-70-26-40(57-43(63)34(51)21-30-13-5-3-6-14-30)47(67)54-37(22-31-15-7-4-8-16-31)45(65)55-38(23-32-24-52-35-18-10-9-17-33(32)35)46(66)53-36(19-11-12-20-50)44(64)59-42(29(2)62)49(69)58-41/h3-10,13-18,24,28-29,34,36-42,52,60-62H,11-12,19-23,25-27,50-51H2,1-2H3,(H,53,66)(H,54,67)(H,55,65)(H,56,68)(H,57,63)(H,58,69)(H,59,64)/t28-,29-,34-,36+,37+,38-,39+,40+,41+,42+/m1/s1
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n/an/an/a 0.610n/an/an/an/an/a



University of Oxford

Curated by ChEMBL


Assay Description
Binding affinity to human SST2 receptor


Bioorg Med Chem 24: 4936-4948 (2016)


Article DOI: 10.1016/j.bmc.2016.08.001
BindingDB Entry DOI: 10.7270/Q2XD13N8
More data for this
Ligand-Target Pair
Somatostatin receptor type 2


(Homo sapiens (Human))
BDBM50192019
PNG
(CHEMBL3966064)
Show SMILES C[C@@H](O)[C@H](CO)NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@H](N)Cc2ccccc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@H](Cc2c([nH]c3ccccc23)C(F)(F)F)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1
Show InChI InChI=1S/C50H65F3N10O10S2/c1-27(65)38(24-64)60-48(72)40-26-75-74-25-39(61-43(67)33(55)21-29-13-5-3-6-14-29)47(71)58-36(22-30-15-7-4-8-16-30)45(69)59-37(23-32-31-17-9-10-18-34(31)56-42(32)50(51,52)53)46(70)57-35(19-11-12-20-54)44(68)63-41(28(2)66)49(73)62-40/h3-10,13-18,27-28,33,35-41,56,64-66H,11-12,19-26,54-55H2,1-2H3,(H,57,70)(H,58,71)(H,59,69)(H,60,72)(H,61,67)(H,62,73)(H,63,68)/t27-,28-,33-,35+,36+,37-,38+,39+,40+,41+/m1/s1
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n/an/an/a 16n/an/an/an/an/a



University of Oxford

Curated by ChEMBL


Assay Description
Binding affinity to human SST2 receptor


Bioorg Med Chem 24: 4936-4948 (2016)


Article DOI: 10.1016/j.bmc.2016.08.001
BindingDB Entry DOI: 10.7270/Q2XD13N8
More data for this
Ligand-Target Pair
Somatostatin receptor type 2


(Homo sapiens (Human))
BDBM50423297
PNG
(CHEMBL251541 | Obelin)
Show SMILES COc1cccc2C[C@@H]3[C@H](C[C@H](CN3C)C(=O)N3CCN(CC3)c3ccc(cc3)[N+]([O-])=O)Cc12
Show InChI InChI=1S/C26H32N4O4/c1-27-17-20(14-19-15-23-18(16-24(19)27)4-3-5-25(23)34-2)26(31)29-12-10-28(11-13-29)21-6-8-22(9-7-21)30(32)33/h3-9,19-20,24H,10-17H2,1-2H3/t19-,20-,24-/m1/s1
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n/an/an/a 3.63E+4n/an/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Binding affinity to human recombinant sst2 receptor


Bioorg Med Chem Lett 17: 3983-7 (2007)


Article DOI: 10.1016/j.bmcl.2007.04.086
BindingDB Entry DOI: 10.7270/Q2XP7675
More data for this
Ligand-Target Pair
Somatostatin receptor type 2


(Homo sapiens (Human))
BDBM50423465
PNG
(ERGOLINE)
Show SMILES CN1C[C@@H](C[C@H]2[C@H]1Cc1c(Br)[nH]c3cccc2c13)C(=O)N1CCN(CC1)c1cccc(=O)n1C
Show InChI InChI=1S/C26H30BrN5O2/c1-29-15-16(13-18-17-5-3-6-20-24(17)19(14-21(18)29)25(27)28-20)26(34)32-11-9-31(10-12-32)22-7-4-8-23(33)30(22)2/h3-8,16,18,21,28H,9-15H2,1-2H3/t16-,18-,21-/m1/s1
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n/an/an/a 1.23E+4n/an/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Binding affinity to human recombinant sst2 receptor


Bioorg Med Chem Lett 18: 979-82 (2008)


Article DOI: 10.1016/j.bmcl.2007.12.030
BindingDB Entry DOI: 10.7270/Q2WQ053B
More data for this
Ligand-Target Pair
Somatostatin receptor type 2


(Homo sapiens (Human))
BDBM50423464
PNG
(CHEMBL252231)
Show SMILES CN1C[C@H](C[C@@H]2[C@@H]1Cc1c(Br)[nH]c3cccc2c13)C(=O)N1CCN(CC1)c1cccc(=O)n1C
Show InChI InChI=1S/C26H30BrN5O2/c1-29-15-16(13-18-17-5-3-6-20-24(17)19(14-21(18)29)25(27)28-20)26(34)32-11-9-31(10-12-32)22-7-4-8-23(33)30(22)2/h3-8,16,18,21,28H,9-15H2,1-2H3/t16-,18-,21-/m0/s1
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n/an/an/a 9.33E+3n/an/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Binding affinity to human recombinant sst2 receptor


Bioorg Med Chem Lett 18: 979-82 (2008)


Article DOI: 10.1016/j.bmcl.2007.12.030
BindingDB Entry DOI: 10.7270/Q2WQ053B
More data for this
Ligand-Target Pair
Somatostatin receptor type 2


(Homo sapiens (Human))
BDBM50423462
PNG
(CHEMBL251835)
Show SMILES CN1C[C@@H](C[C@H]2[C@H]1Cc1c(Br)[nH]c3cccc2c13)C(=O)N1CCN(CC1)c1ccc2nonc2c1
Show InChI InChI=1S/C26H27BrN6O2/c1-31-14-15(11-18-17-3-2-4-21-24(17)19(13-23(18)31)25(27)28-21)26(34)33-9-7-32(8-10-33)16-5-6-20-22(12-16)30-35-29-20/h2-6,12,15,18,23,28H,7-11,13-14H2,1H3/t15-,18-,23-/m1/s1
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n/an/an/a 6.76E+3n/an/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Binding affinity to human recombinant sst2 receptor


Bioorg Med Chem Lett 18: 979-82 (2008)


Article DOI: 10.1016/j.bmcl.2007.12.030
BindingDB Entry DOI: 10.7270/Q2WQ053B
More data for this
Ligand-Target Pair
Somatostatin receptor type 2


(Homo sapiens (Human))
BDBM50423458
PNG
(CHEMBL252232)
Show SMILES CN1C[C@H](C[C@@H]2[C@@H]1Cc1c(Br)[nH]c3cccc2c13)C(=O)N1CCN(CC1)c1ccc2nonc2c1
Show InChI InChI=1S/C26H27BrN6O2/c1-31-14-15(11-18-17-3-2-4-21-24(17)19(13-23(18)31)25(27)28-21)26(34)33-9-7-32(8-10-33)16-5-6-20-22(12-16)30-35-29-20/h2-6,12,15,18,23,28H,7-11,13-14H2,1H3/t15-,18-,23-/m0/s1
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n/an/an/a 3.89E+3n/an/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Binding affinity to human recombinant sst2 receptor


Bioorg Med Chem Lett 18: 979-82 (2008)


Article DOI: 10.1016/j.bmcl.2007.12.030
BindingDB Entry DOI: 10.7270/Q2WQ053B
More data for this
Ligand-Target Pair
Somatostatin receptor type 2


(Homo sapiens (Human))
BDBM50192018
PNG
(CHEMBL3350037)
Show SMILES C[C@@H](O)[C@H](CO)NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@H](N)Cc2ccccc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1
Show InChI InChI=1S/C49H66N10O10S2/c1-28(61)39(25-60)56-48(68)41-27-71-70-26-40(57-43(63)34(51)21-30-13-5-3-6-14-30)47(67)54-37(22-31-15-7-4-8-16-31)45(65)55-38(23-32-24-52-35-18-10-9-17-33(32)35)46(66)53-36(19-11-12-20-50)44(64)59-42(29(2)62)49(69)58-41/h3-10,13-18,24,28-29,34,36-42,52,60-62H,11-12,19-23,25-27,50-51H2,1-2H3,(H,53,66)(H,54,67)(H,55,65)(H,56,68)(H,57,63)(H,58,69)(H,59,64)/t28-,29-,34-,36+,37+,38-,39+,40+,41+,42+/m1/s1
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n/an/an/a 0.776n/an/an/an/an/a



ETH Zurich

Curated by ChEMBL


Assay Description
Binding assay at human somatostatin receptor 2 (hsst2) expressed in CCL-39 cells using LTT-CST-14-(Tyr10) as radioligand.


J Med Chem 44: 2460-8 (2001)


Article DOI: 10.1021/jm010816q
BindingDB Entry DOI: 10.7270/Q2C53PKS
More data for this
Ligand-Target Pair
Somatostatin receptor type 2


(Homo sapiens (Human))
BDBM50473329
PNG
(CHEMBL311789)
Show SMILES C[C@@H](O)[C@@H](CC(=O)NC[C@H](CCCCN)C(=O)N[C@H](CC(=O)N[C@H](CC(N)=O)Cc1ccccc1)Cc1c[nH]c2ccccc12)NC(C)=O
Show InChI InChI=1S/C36H51N7O6/c1-23(44)32(41-24(2)45)20-34(47)40-21-26(12-8-9-15-37)36(49)43-29(17-27-22-39-31-14-7-6-13-30(27)31)19-35(48)42-28(18-33(38)46)16-25-10-4-3-5-11-25/h3-7,10-11,13-14,22-23,26,28-29,32,39,44H,8-9,12,15-21,37H2,1-2H3,(H2,38,46)(H,40,47)(H,41,45)(H,42,48)(H,43,49)/t23-,26+,28+,29+,32-/m1/s1
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n/an/an/a<1.00E+4n/an/an/an/an/a



ETH Zurich

Curated by ChEMBL


Assay Description
Binding assay at human somatostatin receptor 2 (hsst2) expressed in CCL-39 cells using LTT-CST-14-(Tyr10) as radioligand.


J Med Chem 44: 2460-8 (2001)


Article DOI: 10.1021/jm010816q
BindingDB Entry DOI: 10.7270/Q2C53PKS
More data for this
Ligand-Target Pair
Somatostatin receptor type 2


(Homo sapiens (Human))
BDBM81767
PNG
(15-28-Somatostatin-28 | CAS_38916-34-6 | CB6417646...)
Show SMILES C[C@@H](O)[C@@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](CO)NC1=O)C(O)=O)NC(=O)CNC(=O)[C@H](C)N)[C@@H](C)O
Show InChI InChI=1S/C76H104N18O19S2/c1-41(79)64(100)82-37-61(99)83-58-39-114-115-40-59(76(112)113)92-72(108)57(38-95)91-75(111)63(43(3)97)94-71(107)54(33-46-23-11-6-12-24-46)90-74(110)62(42(2)96)93-66(102)51(28-16-18-30-78)84-69(105)55(34-47-36-81-49-26-14-13-25-48(47)49)88-68(104)53(32-45-21-9-5-10-22-45)86-67(103)52(31-44-19-7-4-8-20-44)87-70(106)56(35-60(80)98)89-65(101)50(85-73(58)109)27-15-17-29-77/h4-14,19-26,36,41-43,50-59,62-63,81,95-97H,15-18,27-35,37-40,77-79H2,1-3H3,(H2,80,98)(H,82,100)(H,83,99)(H,84,105)(H,85,109)(H,86,103)(H,87,106)(H,88,104)(H,89,101)(H,90,110)(H,91,111)(H,92,108)(H,93,102)(H,94,107)(H,112,113)/t41-,42+,43+,50-,51-,52-,53-,54-,55-,56-,57-,58-,59-,62-,63-/m0/s1
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n/an/an/a 0.0871n/an/an/an/an/a



ETH Zurich

Curated by ChEMBL


Assay Description
Binding assay at human somatostatin receptor 2 (hsst2) expressed in CCL-39 cells using LTT-CST-14-(Tyr10) as radioligand.


J Med Chem 44: 2460-8 (2001)


Article DOI: 10.1021/jm010816q
BindingDB Entry DOI: 10.7270/Q2C53PKS
More data for this
Ligand-Target Pair
Somatostatin receptor type 2


(Homo sapiens (Human))
BDBM50473330
PNG
(CHEMBL309948)
Show SMILES C[C@@H](O)[C@H](NC(C)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C32H43N7O6/c1-19(40)28(36-20(2)41)32(45)37-25(14-8-9-15-33)30(43)39-27(17-22-18-35-24-13-7-6-12-23(22)24)31(44)38-26(29(34)42)16-21-10-4-3-5-11-21/h3-7,10-13,18-19,25-28,35,40H,8-9,14-17,33H2,1-2H3,(H2,34,42)(H,36,41)(H,37,45)(H,38,44)(H,39,43)/t19-,25+,26+,27+,28+/m1/s1
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n/an/an/a<1.00E+5n/an/an/an/an/a



ETH Zurich

Curated by ChEMBL


Assay Description
Binding assay at human somatostatin receptor 2 (hsst2) expressed in CCL-39 cells using LTT-CST-14-(Tyr10) as radioligand.


J Med Chem 44: 2460-8 (2001)


Article DOI: 10.1021/jm010816q
BindingDB Entry DOI: 10.7270/Q2C53PKS
More data for this
Ligand-Target Pair
Somatostatin receptor type 2


(Homo sapiens (Human))
BDBM50065453
PNG
((5S,8S,11S,14R,17S,19aS)-11-(4-Amino-butyl)-5,17-d...)
Show SMILES C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2ccccc2)NC1=O
Show InChI InChI=1S/C44H54N8O7/c1-27(53)38-43(58)50-36(24-29-15-6-3-7-16-29)44(59)52-22-12-20-37(52)42(57)49-34(23-28-13-4-2-5-14-28)40(55)48-35(25-30-26-46-32-18-9-8-17-31(30)32)41(56)47-33(39(54)51-38)19-10-11-21-45/h2-9,13-18,26-27,33-38,46,53H,10-12,19-25,45H2,1H3,(H,47,56)(H,48,55)(H,49,57)(H,50,58)(H,51,54)/t27-,33+,34+,35-,36+,37+,38+/m1/s1
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n/an/an/a 0.760n/an/an/an/an/a



University of California San Diego

Curated by ChEMBL


Assay Description
In vitro inhibition of radioligand binding to human somatostatin receptor (hsst2) expressed in CHO cells.


J Med Chem 41: 2679-85 (1998)


Article DOI: 10.1021/jm970393l
BindingDB Entry DOI: 10.7270/Q2Z60N6X
More data for this
Ligand-Target Pair