Compile Data Set for Download or QSAR
maximum 50k data
Found 149 of ic50 data for polymerid = 7498
TargetAlpha-synuclein(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50389294(CHEMBL2063787)
Affinity DataIC50:  134nMAssay Description:Binding affinity to human alpha-synuclein expressed in Escherichia coli BL21 (DE3) cells after 1 hr by thioflavin T fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-synuclein(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50553255(All-Trans-Retinal | CHEBI:17898 | Retinal)
Affinity DataIC50:  190nMAssay Description:Inhibition of alpha-synuclein fibril formation (unknown origin) incubated for 24 hrs to 7 days by thioflavin S based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-synuclein(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50092056((2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclo...)
Affinity DataIC50:  190nMAssay Description:Inhibition of alpha-synuclein fibril formation (unknown origin) incubated for 24 hrs to 7 days by thioflavin S based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-synuclein(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50389304(CHEMBL2063797)
Affinity DataIC50:  204nMAssay Description:Binding affinity to human alpha-synuclein expressed in Escherichia coli BL21 (DE3) cells after 1 hr by thioflavin T fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-synuclein(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50133496((2R)-3-(3,4-dihydroxyphenyl)-2-[(2E)-3-(3,4-dihydr...)
Affinity DataIC50:  210nMAssay Description:Inhibition of alpha-synuclein fibril formation (unknown origin) incubated for 24 hrs to 7 days by thioflavin S based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-synuclein(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM32020(4-[4-(3,4-dihydroxyphenyl)-2,3-dimethyl-butyl]pyro...)
Affinity DataIC50:  210nMAssay Description:Inhibition of alpha-synuclein aggregation (unknown origin) incubated for 8 days by thioflavin S based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-synuclein(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM15236(3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-chr...)
Affinity DataIC50:  220nMAssay Description:Inhibition of alpha-synuclein fibril formation (unknown origin) incubated for 24 hrs to 7 days by thioflavin S based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-synuclein(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM32020(4-[4-(3,4-dihydroxyphenyl)-2,3-dimethyl-butyl]pyro...)
Affinity DataIC50:  220nMAssay Description:Inhibition of alpha-synuclein fibril formation (unknown origin) incubated for 24 hrs to 7 days by thioflavin S based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-synuclein(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50140172(CHEBI:3962 | CHEMBL140 | Curcumin | US9409845, Tab...)
Affinity DataIC50:  220nMAssay Description:Inhibition of alpha-synuclein fibril formation (unknown origin) incubated for 24 hrs to 7 days by thioflavin S based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-synuclein(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50389305(CHEMBL2063798)
Affinity DataIC50:  241nMAssay Description:Binding affinity to human alpha-synuclein expressed in Escherichia coli BL21 (DE3) cells after 1 hr by thioflavin T fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-synuclein(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50553254(CHEMBL4787961)
Affinity DataIC50:  250nMAssay Description:Inhibition of alpha-synuclein fibril formation (unknown origin) incubated for 24 hrs to 7 days by thioflavin S based fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetAlpha-synuclein(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM510815(N-(1-(1H-Indol-3-yl)hexan-2- yl)-2-(piperazin-1-yl...)
Affinity DataIC50:  270nMAssay Description:The fluorescence polarization assay tests the ability of compounds to inhibit the self-aggregation of α-synuclein peptide fragments. Peptides we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-synuclein(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM15579(CHEMBL972 | DEPRENYL | L-Deprenyl | N-methyl-N-[(2...)
Affinity DataIC50:  270nMAssay Description:Inhibition of alpha-synuclein fibril formation (unknown origin) incubated for 6 days by thioflavin S based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-synuclein(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50389295(CHEMBL2063788)
Affinity DataIC50:  314nMAssay Description:Binding affinity to human alpha-synuclein expressed in Escherichia coli BL21 (DE3) cells after 1 hr by thioflavin T fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-synuclein(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM510819(N-(1-(1H-Indol-3-yl)hexan-2- yl)-5-(4-methylpipera...)
Affinity DataIC50:  370nMAssay Description:The fluorescence polarization assay tests the ability of compounds to inhibit the self-aggregation of α-synuclein peptide fragments. Peptides we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-synuclein(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM510818(N-(1-(1H-Indol-3-yl)hexan-2- yl)-2-(4-methylpipera...)
Affinity DataIC50:  390nMAssay Description:The fluorescence polarization assay tests the ability of compounds to inhibit the self-aggregation of α-synuclein peptide fragments. Peptides we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-synuclein(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM481754(N-[1-(1H-indol-3- ylmethyl)pentyl]-2-(4- phenylpip...)
Affinity DataIC50:  400nMAssay Description:The fluorescence polarization assay tests the ability of compounds to inhibit the self-aggregation of α-synuclein peptide fragments. Peptides we...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAlpha-synuclein(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM510822((S)-N-(1-(1H-Indol-3-yl)hexan- 2-yl)-2-(4-methylpi...)
Affinity DataIC50:  400nMAssay Description:The fluorescence polarization assay tests the ability of compounds to inhibit the self-aggregation of α-synuclein peptide fragments. Peptides we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-synuclein(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50389296(CHEMBL2063789)
Affinity DataIC50:  442nMAssay Description:Binding affinity to human alpha-synuclein expressed in Escherichia coli BL21 (DE3) cells after 1 hr by thioflavin T fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-synuclein(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50389291(CHEMBL1976750)
Affinity DataIC50:  485nMAssay Description:Binding affinity to human alpha-synuclein expressed in Escherichia coli BL21 (DE3) cells after 1 hr by thioflavin T fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-synuclein(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50389292(CHEMBL2063785)
Affinity DataIC50:  507nMAssay Description:Binding affinity to human alpha-synuclein expressed in Escherichia coli BL21 (DE3) cells after 1 hr by thioflavin T fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-synuclein(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM55121(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Affinity DataIC50:  530nMAssay Description:Inhibition of alpha-synuclein fibril formation (unknown origin) incubated for 6 days by thioflavin S based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-synuclein(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM510823((R)-N-(1-(1H-Indol-3-yl)hexan- 2-yl)-2-(4-methylpi...)
Affinity DataIC50:  700nMAssay Description:The fluorescence polarization assay tests the ability of compounds to inhibit the self-aggregation of α-synuclein peptide fragments. Peptides we...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAlpha-synuclein(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50214744((2E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic aci...)
Affinity DataIC50:  750nMAssay Description:Inhibition of alpha-synuclein fibril formation (unknown origin) incubated for 24 hrs to 7 days by thioflavin S based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-synuclein(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM510820(N-(1-(1H-Indol-3-yl)hexan-2- yl)-5-(4-methylpipera...)
Affinity DataIC50:  770nMAssay Description:The fluorescence polarization assay tests the ability of compounds to inhibit the self-aggregation of α-synuclein peptide fragments. Peptides we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-synuclein(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM481757(N-[1-(1H-indol-3- ylmethyl)pentyl]-2-[4-(1- methyl...)
Affinity DataIC50:  800nMAssay Description:The fluorescence polarization assay tests the ability of compounds to inhibit the self-aggregation of α-synuclein peptide fragments. Peptides we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-synuclein(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM23417(α-CA inhibitor, 4 | (-)-Epicatechin | (2R,3R)...)
Affinity DataIC50:  800nMAssay Description:Inhibition of alpha-synuclein fibril formation (unknown origin) incubated for 24 hrs to 7 days by thioflavin S based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-synuclein(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM491842(N-(1-(1H-indol-3- yl)hexan-2-yl)- 2-(4-isobutyl- p...)
Affinity DataIC50:  900nMAssay Description:The fluorescence polarization assay tests the ability of compounds to inhibit the self-aggregation of α-synuclein peptide fragments. Peptides we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-synuclein(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM481758(N-[1-(1H-indol-3- ylmethyl)pentyl]-2-[4-(2- methyl...)
Affinity DataIC50:  900nMAssay Description:The fluorescence polarization assay tests the ability of compounds to inhibit the self-aggregation of α-synuclein peptide fragments. Peptides we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-synuclein(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM481749(N-[1-(1H-indol-3- ylmethyl)pentyl]-2-[4-(2- pyridy...)
Affinity DataIC50:  900nMAssay Description:The fluorescence polarization assay tests the ability of compounds to inhibit the self-aggregation of α-synuclein peptide fragments. Peptides we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-synuclein(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50544150(CHEMBL4641523)
Affinity DataIC50:  980nMAssay Description:Inhibition of alpha-synuclein (unknown origin) aggregation incubated for 3 days by thioflavin T based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-synuclein(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM491846(N-(1-(1H-indol-3- yl)hexan-2-yl)-2- (4-(2,2,2-trif...)
Affinity DataIC50:  1.00E+3nMAssay Description:The fluorescence polarization assay tests the ability of compounds to inhibit the self-aggregation of α-synuclein peptide fragments. Peptides we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-synuclein(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM491847(N-(1-(1H-indol-3- yl)hexan-2-yl)-2- (4-(3,3,3-trif...)
Affinity DataIC50:  1.00E+3nMAssay Description:The fluorescence polarization assay tests the ability of compounds to inhibit the self-aggregation of α-synuclein peptide fragments. Peptides we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-synuclein(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM481745(N-[1-(1H-indol-3- ylmethyl)pentyl]-2-(4- pyrimidin...)
Affinity DataIC50:  1.00E+3nMAssay Description:The fluorescence polarization assay tests the ability of compounds to inhibit the self-aggregation of α-synuclein peptide fragments. Peptides we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-synuclein(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM481747(N-[1-(1H-indol-3- ylmethyl)pentyl]-2-[4-(3- pyridy...)
Affinity DataIC50:  1.00E+3nMAssay Description:The fluorescence polarization assay tests the ability of compounds to inhibit the self-aggregation of α-synuclein peptide fragments. Peptides we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-synuclein(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM481756(N-[1-(1H-indol-3- ylmethyl)pentyl]-2-[4-(1H- pyraz...)
Affinity DataIC50:  1.00E+3nMAssay Description:The fluorescence polarization assay tests the ability of compounds to inhibit the self-aggregation of α-synuclein peptide fragments. Peptides we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-synuclein(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50510750(CHEMBL4551721)
Affinity DataIC50:  1.09E+3nMAssay Description:Inhibition of alpha-synuclein aggregation (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 days by thioflavin T fluorescence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAlpha-synuclein(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM481755(N-[1-(1H-indol-3- ylmethyl)pentyl]-2-[4-(1H- pyraz...)
Affinity DataIC50:  1.10E+3nMAssay Description:The fluorescence polarization assay tests the ability of compounds to inhibit the self-aggregation of α-synuclein peptide fragments. Peptides we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-synuclein(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM491843(N-(1-(1H-indol-3- yl)hexan-2-yl)- 2-(4-(2-methoxy-...)
Affinity DataIC50:  1.10E+3nMAssay Description:The fluorescence polarization assay tests the ability of compounds to inhibit the self-aggregation of α-synuclein peptide fragments. Peptides we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-synuclein(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM491859(US10975066, Example 24)
Affinity DataIC50:  1.10E+3nMAssay Description:The fluorescence polarization assay tests the ability of compounds to inhibit the self-aggregation of α-synuclein peptide fragments. Peptides we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-synuclein(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM491840(N-(1-(1H-indol-3- yl)hexan-2-yl)-2- (4-cyclopropyl...)
Affinity DataIC50:  1.10E+3nMAssay Description:The fluorescence polarization assay tests the ability of compounds to inhibit the self-aggregation of α-synuclein peptide fragments. Peptides we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-synuclein(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM481750(N-[1-(1H-indol-3- ylmethyl)pentyl]-2-(4- pyrimidin...)
Affinity DataIC50:  1.10E+3nMAssay Description:The fluorescence polarization assay tests the ability of compounds to inhibit the self-aggregation of α-synuclein peptide fragments. Peptides we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-synuclein(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM491850(N-(1-(1H-indol- 3-yl)hexan-2-yl)- 2-(cis-3,4,5- tr...)
Affinity DataIC50:  1.20E+3nMAssay Description:The fluorescence polarization assay tests the ability of compounds to inhibit the self-aggregation of α-synuclein peptide fragments. Peptides we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-synuclein(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM491839(N-(1-(1H-indol-3- yl)hexan-2-yl)-2-(4- isopropylpi...)
Affinity DataIC50:  1.20E+3nMAssay Description:The fluorescence polarization assay tests the ability of compounds to inhibit the self-aggregation of α-synuclein peptide fragments. Peptides we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-synuclein(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM491853(N-(2-(1H-indol-3- yl)ethyl)-N-butyl- 2-(4-methyl- ...)
Affinity DataIC50:  1.20E+3nMAssay Description:The fluorescence polarization assay tests the ability of compounds to inhibit the self-aggregation of α-synuclein peptide fragments. Peptides we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-synuclein(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM491844(N-(1-(1H-indol-3- yl)hexan-2-yl)-2- (4-(2-fluoroet...)
Affinity DataIC50:  1.20E+3nMAssay Description:The fluorescence polarization assay tests the ability of compounds to inhibit the self-aggregation of α-synuclein peptide fragments. Peptides we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-synuclein(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM481753(N-[1-(1H-indol-3- ylmethyl)pentyl]-2-(4- pyrazin-2...)
Affinity DataIC50:  1.20E+3nMAssay Description:The fluorescence polarization assay tests the ability of compounds to inhibit the self-aggregation of α-synuclein peptide fragments. Peptides we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-synuclein(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM491845(N-(1-(1H-indol-3- yl)hexan-2-yl)-2- (4-(2,2-difluo...)
Affinity DataIC50:  1.20E+3nMAssay Description:The fluorescence polarization assay tests the ability of compounds to inhibit the self-aggregation of α-synuclein peptide fragments. Peptides we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-synuclein(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50544151(CHEMBL4640362)
Affinity DataIC50:  1.22E+3nMAssay Description:Inhibition of alpha-synuclein (unknown origin) aggregation incubated for 3 days by thioflavin T based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-synuclein(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM510817(N-(1-(1H-Indol-3-yl)hexan-2- yl)-2-(2-(4-methylpip...)
Affinity DataIC50:  1.30E+3nMAssay Description:The fluorescence polarization assay tests the ability of compounds to inhibit the self-aggregation of α-synuclein peptide fragments. Peptides we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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