Compile Data Set for Download or QSAR
maximum 50k data
Found 13 of ki for UniProtKB: P10153
TargetNon-secretory ribonuclease(Homo sapiens (Human))
Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50292713(5'-phospho-2'-deoxyuridine 3-pyrophosphate (P'->5'...)
Affinity DataKi:  180nMAssay Description:Inhibition of human EDNMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNon-secretory ribonuclease(Homo sapiens (Human))
Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50402338(CHEMBL401150)
Affinity DataKi:  180nMAssay Description:Inhibition of EDNMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNon-secretory ribonuclease(Homo sapiens (Human))
Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM173618(1-[(2R,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2...)
Affinity DataKi:  2.61E+4nM ΔG°:  -6.35kcal/mole IC50:  3.31E+4nMT: 2°CAssay Description:The Ribonuclease Activity assay used was adapted from the procedure described by Anfinsen et al. and Slifman et al. Determination of ribonuclease act...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNon-secretory ribonuclease(Homo sapiens (Human))
Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM173617(1-({1-[(2R,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxol...)
Affinity DataKi:  4.42E+4nM ΔG°:  -6.04kcal/mole IC50:  6.37E+4nMT: 2°CAssay Description:The Ribonuclease Activity assay used was adapted from the procedure described by Anfinsen et al. and Slifman et al. Determination of ribonuclease act...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNon-secretory ribonuclease(Homo sapiens (Human))
Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM173612(9-[3'-[4-[(Cytosine-1-yl)methyl]-1,2,3-triazol...)
Affinity DataKi:  5.78E+4nM ΔG°:  -5.87kcal/mole IC50:  8.86E+4nMT: 2°CAssay Description:The Ribonuclease Activity assay used was adapted from the procedure described by Anfinsen et al. and Slifman et al. Determination of ribonuclease act...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNon-secretory ribonuclease(Homo sapiens (Human))
Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM173615(1-({1-[(2R,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxol...)
Affinity DataKi:  1.16E+5nM ΔG°:  -5.45kcal/mole IC50:  1.79E+5nMT: 2°CAssay Description:The Ribonuclease Activity assay used was adapted from the procedure described by Anfinsen et al. and Slifman et al. Determination of ribonuclease act...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNon-secretory ribonuclease(Homo sapiens (Human))
Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM173620(1-[(2R,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2...)
Affinity DataKi:  2.08E+5nM ΔG°:  -5.10kcal/mole IC50:  2.82E+5nMT: 2°CAssay Description:The Ribonuclease Activity assay used was adapted from the procedure described by Anfinsen et al. and Slifman et al. Determination of ribonuclease act...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNon-secretory ribonuclease(Homo sapiens (Human))
Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM173611(9-[3'-[4-[(Thymine-1-yl)methyl]-1,2,3-triazol-...)
Affinity DataKi:  2.48E+5nM ΔG°:  -5.00kcal/mole IC50:  3.79E+5nMT: 2°CAssay Description:The Ribonuclease Activity assay used was adapted from the procedure described by Anfinsen et al. and Slifman et al. Determination of ribonuclease act...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNon-secretory ribonuclease(Homo sapiens (Human))
Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM173610(9-[3'-[4-[(Uracil-1-yl)methyl]-1,2,3-triazol-1...)
Affinity DataKi:  2.67E+5nM ΔG°:  -4.95kcal/mole IC50:  4.09E+5nMT: 2°CAssay Description:The Ribonuclease Activity assay used was adapted from the procedure described by Anfinsen et al. and Slifman et al. Determination of ribonuclease act...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNon-secretory ribonuclease(Homo sapiens (Human))
Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM173614(9-[3'-[4-[(Thymine-1-yl)methyl]-1,2,3-triazol-...)
Affinity DataKi:  3.65E+5nM ΔG°:  -4.76kcal/mole IC50:  5.59E+5nMT: 2°CAssay Description:The Ribonuclease Activity assay used was adapted from the procedure described by Anfinsen et al. and Slifman et al. Determination of ribonuclease act...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNon-secretory ribonuclease(Homo sapiens (Human))
Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM173613(9-[3'-[4-[(Uracil-1-yl)methyl]-1,2,3-triazol-1...)
Affinity DataKi:  4.26E+5nM ΔG°:  -4.67kcal/mole IC50:  6.52E+5nMT: 2°CAssay Description:The Ribonuclease Activity assay used was adapted from the procedure described by Anfinsen et al. and Slifman et al. Determination of ribonuclease act...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNon-secretory ribonuclease(Homo sapiens (Human))
Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM173616(5-chloro-1-({1-[(2R,5R)-3,4-dihydroxy-5-(hydroxyme...)
Affinity DataKi:  4.54E+5nM ΔG°:  -4.63kcal/mole IC50:  5.35E+5nMT: 2°CAssay Description:The Ribonuclease Activity assay used was adapted from the procedure described by Anfinsen et al. and Slifman et al. Determination of ribonuclease act...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNon-secretory ribonuclease(Homo sapiens (Human))
Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM173619(5-chloro-1-[(2R,5R)-3,4-dihydroxy-5-(hydroxymethyl...)
Affinity DataKi:  1.08E+6nM ΔG°:  -4.11kcal/mole IC50:  1.46E+6nMT: 2°CAssay Description:The Ribonuclease Activity assay used was adapted from the procedure described by Anfinsen et al. and Slifman et al. Determination of ribonuclease act...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed