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Compile Data Set for Download or QSAR

Found 7 hits of ic50 data for polymerid = 7634   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Adenosine receptor A3 (A3)


(Homo sapiens (Human))
BDBM50310923
PNG
(CHEMBL1077943 | US9120807, 6 | {6-Methylamino-2-[(...)
Show SMILES CNc1cc2nc(NCc3cccnc3)nc(C(=O)c3cccs3)c2s1
Show InChI InChI=1S/C18H15N5OS2/c1-19-14-8-12-17(26-14)15(16(24)13-5-3-7-25-13)23-18(22-12)21-10-11-4-2-6-20-9-11/h2-9,19H,10H2,1H3,(H,21,22,23)
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UniChem

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US Patent
n/an/a 22.9n/an/an/an/an/an/a



Vernalis (R&D) Ltd.

US Patent


Assay Description
The use of a Fluorometric Imaging Plate Reader (FLIPR) to measure calcium flux in Adenosine-receptor expressing cells is a well-established technique...


US Patent US9120807 (2015)

More data for this
Ligand-Target Pair
Adenosine receptor A3 (A3)


(Homo sapiens (Human))
BDBM50310924
PNG
(CHEMBL1080421 | US9120807, 8 | {6-Ethylamino-2-[(p...)
Show SMILES CCNc1cc2nc(NCc3cccnc3)nc(C(=O)c3cccs3)c2s1
Show InChI InChI=1S/C19H17N5OS2/c1-2-21-15-9-13-18(27-15)16(17(25)14-6-4-8-26-14)24-19(23-13)22-11-12-5-3-7-20-10-12/h3-10,21H,2,11H2,1H3,(H,22,23,24)
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US Patent
n/an/a 37.3n/an/an/an/an/an/a



Vernalis (R&D) Ltd.

US Patent


Assay Description
The use of a Fluorometric Imaging Plate Reader (FLIPR) to measure calcium flux in Adenosine-receptor expressing cells is a well-established technique...


US Patent US9120807 (2015)

More data for this
Ligand-Target Pair
Adenosine receptor A3 (A3)


(Homo sapiens (Human))
BDBM50310925
PNG
(CHEMBL1081160 | US9120807, 7 | {6-dimethylamino-2-...)
Show SMILES CN(C)c1cc2nc(NCc3cccnc3)nc(C(=O)c3cccs3)c2s1
Show InChI InChI=1S/C19H17N5OS2/c1-24(2)15-9-13-18(27-15)16(17(25)14-6-4-8-26-14)23-19(22-13)21-11-12-5-3-7-20-10-12/h3-10H,11H2,1-2H3,(H,21,22,23)
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US Patent
n/an/a 130n/an/an/an/an/an/a



Vernalis (R&D) Ltd.

US Patent


Assay Description
The use of a Fluorometric Imaging Plate Reader (FLIPR) to measure calcium flux in Adenosine-receptor expressing cells is a well-established technique...


US Patent US9120807 (2015)

More data for this
Ligand-Target Pair
Adenosine receptor A3 (A3)


(Homo sapiens (Human))
BDBM50310922
PNG
(CHEMBL1080241 | US9120807, 9 | {6-Amino-2-[(pyridi...)
Show SMILES Nc1cc2nc(NCc3cccnc3)nc(C(=O)c3cccs3)c2s1
Show InChI InChI=1S/C17H13N5OS2/c18-13-7-11-16(25-13)14(15(23)12-4-2-6-24-12)22-17(21-11)20-9-10-3-1-5-19-8-10/h1-8H,9,18H2,(H,20,21,22)
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US Patent
n/an/a 233n/an/an/an/an/an/a



Vernalis (R&D) Ltd.

US Patent


Assay Description
The use of a Fluorometric Imaging Plate Reader (FLIPR) to measure calcium flux in Adenosine-receptor expressing cells is a well-established technique...


US Patent US9120807 (2015)

More data for this
Ligand-Target Pair
Adenosine receptor A3 (A3)


(Homo sapiens (Human))
BDBM178000
PNG
(US9120807, 12)
Show SMILES O=C(c1cccs1)c1nc(NCc2cccnc2)nc2cc(NCc3cccnc3)sc12
Show InChI InChI=1S/C23H18N6OS2/c30-21(18-6-3-9-31-18)20-22-17(10-19(32-22)26-13-15-4-1-7-24-11-15)28-23(29-20)27-14-16-5-2-8-25-12-16/h1-12,26H,13-14H2,(H,27,28,29)
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US Patent
n/an/a 308n/an/an/an/an/an/a



Vernalis (R&D) Ltd.

US Patent


Assay Description
The use of a Fluorometric Imaging Plate Reader (FLIPR) to measure calcium flux in Adenosine-receptor expressing cells is a well-established technique...


US Patent US9120807 (2015)

More data for this
Ligand-Target Pair
Adenosine receptor A3 (A3)


(Homo sapiens (Human))
BDBM177999
PNG
(US9120807, 11)
Show SMILES CCc1cc2nc(NCc3cccnc3)nc(C(=O)c3cccs3)c2s1
Show InChI InChI=1S/C19H16N4OS2/c1-2-13-9-14-18(26-13)16(17(24)15-6-4-8-25-15)23-19(22-14)21-11-12-5-3-7-20-10-12/h3-10H,2,11H2,1H3,(H,21,22,23)
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US Patent
n/an/a 361n/an/an/an/an/an/a



Vernalis (R&D) Ltd.

US Patent


Assay Description
The use of a Fluorometric Imaging Plate Reader (FLIPR) to measure calcium flux in Adenosine-receptor expressing cells is a well-established technique...


US Patent US9120807 (2015)

More data for this
Ligand-Target Pair
Adenosine receptor A3 (A3)


(Homo sapiens (Human))
BDBM177998
PNG
(US9120807, 10)
Show SMILES C=Cc1cc2nc(NCc3cccnc3)nc(C(=O)c3cccs3)c2s1
Show InChI InChI=1S/C19H14N4OS2/c1-2-13-9-14-18(26-13)16(17(24)15-6-4-8-25-15)23-19(22-14)21-11-12-5-3-7-20-10-12/h2-10H,1,11H2,(H,21,22,23)
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PC cid
PC sid
UniChem

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US Patent
n/an/a 747n/an/an/an/an/an/a



Vernalis (R&D) Ltd.

US Patent


Assay Description
The use of a Fluorometric Imaging Plate Reader (FLIPR) to measure calcium flux in Adenosine-receptor expressing cells is a well-established technique...


US Patent US9120807 (2015)

More data for this
Ligand-Target Pair