TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Inhibition of Fyn (unknown origin) using Src-family kinase bisamide rhodamine 110 peptide substrate after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
Affinity DataIC50: 0.360nMAssay Description:Binding affinity to human FYN using poly[Glu:Tyr] (4:1) as substrate by radiometric hotspot kinase assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
Affinity DataIC50: 0.5nMT: 2°CAssay Description:Kinase activity (Src-family kinases, Hck, Lyn, Fyn, and c-Src) and the effect of the molecules were determined by ProFluor Src-Family Kinase Assay Ki...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
Affinity DataIC50: <0.5nMAssay Description:Inhibition of human FYN using poly[Glu,Tyr]4:1 as substrate in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:inhibitory activity against Fyn protein kinaseMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Inhibition of human FYN using poly[Glu:Tyr] (4:1) as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
Affinity DataIC50: 1.60nMAssay Description:Inhibition of Fyn A (unknown origin) preincubated for 10 mins followed by substrate addition and measured after 1 hr by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
Affinity DataIC50: 1.60nMAssay Description:Inhibition of Fyn A (unknown origin) preincubated for 10 mins followed by substrate addition and measured after 1 hr by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of [3H]-FPP incorporation into biotin-linked K-ras decapeptide (CVIM) by bovine farnesyltransferaseMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
Affinity DataIC50: 2.10nMAssay Description:Inhibition of human FYN using poly[Glu:Tyr] (4:1) as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
Affinity DataIC50: 2.10nMAssay Description:Inhibition of human FYN using poly[Glu,Tyr]4:1 as substrate in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
Affinity DataIC50: 2.20nMAssay Description:Inhibition of human Fyn using Cdc2 peptide as substrate incubated for 40 mins in presence of [gamma-33P]-ATP by radiometric scintillation assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
Affinity DataIC50: 2.70nMAssay Description:Inhibition of from NanoLuc-fused Fyn (unknown origin) transfected in HEK293 cells using tracer K4 incubated for 1 hr by NanoBRET assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:The aim of this experiment is to detect the inhibitory activity of the compounds of the present invention against in vitro protein kinases using isot...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of Fyn protein kinaseMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
Affinity DataIC50: 4.40nMAssay Description:Inhibition of FYN (unknown origin) incubated for 1 hr by spectrophotometric analysisMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of human FynMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of human Fyn expressed in Sf9 cells after 1 min by ELISA in presence of 1 umol/L ATPMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
Affinity DataIC50: <5nMAssay Description:IC50 Table 13-20: The protocol calls for test compound of the invention to be incubated with kinase, substrate, cofactors, and radio-isotope-labeled ...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:The aim of this experiment is to detect the inhibitory activity of the compounds of the present invention against in vitro protein kinases using isot...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
Affinity DataIC50: >5nMAssay Description:Inhibition of Fyn protein kinaseMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
Affinity DataIC50: <5nMAssay Description:IC50 Table 13-20: The protocol calls for test compound of the invention to be incubated with kinase, substrate, cofactors, and radio-isotope-labeled ...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of [3H]-FPP incorporation into biotin-linked K-ras decapeptide (CVIM) by bovine farnesyltransferaseMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
Affinity DataIC50: <5nMAssay Description:IC50 Table 13-20: The protocol calls for test compound of the invention to be incubated with kinase, substrate, cofactors, and radio-isotope-labeled ...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of human full length recombinant FYN using Cdc2 peptide as substrate incubated for 40 mins in presence of [gamma33P-ATP] by radiometric sc...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of protein tyrosine kinasesMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:The assay procedure determines the IC50 of each potential FYN kinase inhibitor by measuring the enzyme catalyzed ATP-dependent phosphorylation of the...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:The assay procedure determines the IC50 of each potential FYN kinase inhibitor by measuring the enzyme catalyzed ATP-dependent phosphorylation of the...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:The aim of this experiment is to detect the inhibitory activity of the compounds of the present invention against in vitro protein kinases using isot...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:The ADP-Glo Kinase Assay is specifically designed to quantify kinase activity by measuring the ADP produced in the reaction The reaction buffer...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:The ADP-Glo Kinase Assay is specifically designed to quantify kinase activity by measuring the ADP produced in the reaction The reaction buffer...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
Affinity DataIC50: 6.69nMAssay Description:The ADP-Glo Kinase Assay is specifically designed to quantify kinase activity by measuring the ADP produced in the reaction The reaction buffer...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
Affinity DataIC50: 6.69nMAssay Description:The assay procedure determines the IC50 of each potential FYN kinase inhibitor by measuring the enzyme catalyzed ATP-dependent phosphorylation of the...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
Affinity DataIC50: 7.10nMAssay Description:IC50s were determined using the in vitro HotSpot kinase assay (purified enzymes, 33P-ATP, an appropriate substrate and 1 uM ATP.). Reaction condition...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
Affinity DataIC50: 7.10nMAssay Description:IC50s were determined using the in vitro HotSpot kinase assay (purified enzymes, 33P-ATP, an appropriate substrate and 1 μM ATP.). For enzyme in...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
Affinity DataIC50: 7.70nMAssay Description:Inhibition of Fyn (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:The ADP-Glo Kinase Assay is specifically designed to quantify kinase activity by measuring the ADP produced in the reaction The reaction buffer...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:The ADP-Glo Kinase Assay is specifically designed to quantify kinase activity by measuring the ADP produced in the reaction The reaction buffer...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:The assay procedure determines the IC50 of each potential FYN kinase inhibitor by measuring the enzyme catalyzed ATP-dependent phosphorylation of the...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:The assay procedure determines the IC50 of each potential FYN kinase inhibitor by measuring the enzyme catalyzed ATP-dependent phosphorylation of the...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of FYN (unknown origin) by cell culture based assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
Affinity DataIC50: <10nMAssay Description:Compound IC50 values were determined from 10-point, 1:3 dilution curves starting at either 100 μM or 10 μM with 10 μM ATP, by Reaction...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant Fyn (unknown origin) using fluoresceinated peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of FYN (unknown origin) by cell culture based assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
Affinity DataIC50: <10nMAssay Description:Compound IC50 values were determined from 10-point, 1:3 dilution curves starting at either 100 μM or 10 μM with 10 μM ATP, by Reaction...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
Affinity DataIC50: <10nMAssay Description:Compound IC50 values were determined from 10-point, 1:3 dilution curves starting at either 100 μM or 10 μM with 10 μM ATP, by Reaction...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
Indo-Soviet Friendship College Of Pharmacy (Isfcp)
Curated by ChEMBL
Affinity DataIC50: <10nMAssay Description:Compound IC50 values were determined from 10-point, 1:3 dilution curves starting at either 100 μM or 10 μM with 10 μM ATP, by Reaction...More data for this Ligand-Target Pair