Compile Data Set for Download or QSAR
maximum 50k data
Found 432 of ic50 data for polymerid = 8165
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Ep811-Cnrs

Curated by ChEMBL
LigandPNGBDBM50009777((ponalrestat)[3-(4-Bromo-2-fluoro-benzyl)-4-oxo-3,...)
Affinity DataIC50:  7nMAssay Description:Evaluated in vitro for the inhibition of Aldose reductase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Ep811-Cnrs

Curated by ChEMBL
LigandPNGBDBM50038843((4R)-2-(4-bromo-2-fluorobenzyl)-6-fluoro-1H,2'H,5'...)
Affinity DataIC50:  9nMAssay Description:In vitro inhibition of aldose reductase activity in a partially purified bovine lens preparationChecked by AuthorMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Ep811-Cnrs

Curated by ChEMBL
LigandPNGBDBM50068078(CHEMBL142239 | {5-[1-(1-Methoxy-naphthalen-2-yl)-m...)
Affinity DataIC50:  9nMAssay Description:Evaluated in vitro for the inhibition of Aldose reductase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Ep811-Cnrs

Curated by ChEMBL
LigandPNGBDBM50038840((4R)-2-[(4-bromo-2-fluorophenyl)methyl]-2,3-dihydr...)
Affinity DataIC50:  10nMAssay Description:In vitro inhibition of aldose reductase activity in a partially purified bovine lens preparationChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Ep811-Cnrs

Curated by ChEMBL
LigandPNGBDBM50068085(CHEMBL358284 | {5-[1-(1-Bromo-naphthalen-2-yl)-met...)
Affinity DataIC50:  11nMAssay Description:Evaluated in vitro for the inhibition of Aldose reductase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Ep811-Cnrs

Curated by ChEMBL
LigandPNGBDBM50038843((4R)-2-(4-bromo-2-fluorobenzyl)-6-fluoro-1H,2'H,5'...)
Affinity DataIC50:  14nMAssay Description:In vitro inhibition of aldose reductase activity in a partially purified bovine lens preparationChecked by AuthorMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Ep811-Cnrs

Curated by ChEMBL
LigandPNGBDBM50038858(2-(1,3-benzothiazol-2-ylmethyl)-1H,2'H,5'H-spiro[i...)
Affinity DataIC50:  15nMAssay Description:In vitro inhibition of aldose reductase activity in a partially purified bovine lens preparationChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Ep811-Cnrs

Curated by ChEMBL
LigandPNGBDBM50068083(CHEMBL358825 | {5-[1-(3-Bromo-naphthalen-2-yl)-met...)
Affinity DataIC50:  15nMAssay Description:Evaluated in vitro for the inhibition of Aldose reductase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Ep811-Cnrs

Curated by ChEMBL
LigandPNGBDBM50038851(2-[3-(trifluoromethyl)benzyl]-1H,2'H,5'H-spiro[iso...)
Affinity DataIC50:  17nMAssay Description:In vitro inhibition of aldose reductase activity in a partially purified bovine lens preparationChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Ep811-Cnrs

Curated by ChEMBL
LigandPNGBDBM50038842(2-(1,3-benzothiazol-2-ylmethyl)-6-fluoro-1H,2'H,5'...)
Affinity DataIC50:  18nMAssay Description:In vitro inhibition of aldose reductase activity in a partially purified bovine lens preparationChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Ep811-Cnrs

Curated by ChEMBL
LigandPNGBDBM50038844(2-(4-bromo-2-fluorobenzyl)-7-fluoro-1H,2'H,5'H-spi...)
Affinity DataIC50:  20nMAssay Description:In vitro inhibition of aldose reductase activity in a partially purified bovine lens preparationChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Ep811-Cnrs

Curated by ChEMBL
LigandPNGBDBM50068086(CHEMBL142701 | {5-[1-(3-Methoxy-naphthalen-2-yl)-m...)
Affinity DataIC50:  20nMAssay Description:Evaluated in vitro for the inhibition of Aldose reductase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Ep811-Cnrs

Curated by ChEMBL
LigandPNGBDBM50038856(2-(4-bromo-2-fluorobenzyl)-5-fluoro-1H,2'H,5'H-spi...)
Affinity DataIC50:  21nMAssay Description:In vitro inhibition of aldose reductase activity in a partially purified bovine lens preparationChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Ep811-Cnrs

Curated by ChEMBL
LigandPNGBDBM50038853(2-{[5-(trifluoromethyl)-1,3-benzothiazol-2-yl]meth...)
Affinity DataIC50:  22nMAssay Description:In vitro inhibition of aldose reductase activity in a partially purified bovine lens preparationChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Ep811-Cnrs

Curated by ChEMBL
LigandPNGBDBM50038838(2-(3,4-dichlorobenzyl)-1H,2'H,5'H-spiro[isoquinoli...)
Affinity DataIC50:  22nMAssay Description:In vitro inhibition of aldose reductase activity in a partially purified bovine lens preparationChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Ep811-Cnrs

Curated by ChEMBL
LigandPNGBDBM50038852(2-(4-bromobenzyl)-1H,2'H,5'H-spiro[isoquinoline-4,...)
Affinity DataIC50:  22nMAssay Description:In vitro inhibition of aldose reductase activity in a partially purified bovine lens preparationChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Ep811-Cnrs

Curated by ChEMBL
LigandPNGBDBM50038862(2-(4-chlorobenzyl)-1H,2'H,5'H-spiro[isoquinoline-4...)
Affinity DataIC50:  22nMAssay Description:In vitro inhibition of aldose reductase activity in a partially purified bovine lens preparationChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Ep811-Cnrs

Curated by ChEMBL
LigandPNGBDBM50038857(2-(4-bromo-2-fluorobenzyl)-8-fluoro-1H,2'H,5'H-spi...)
Affinity DataIC50:  23nMAssay Description:In vitro inhibition of aldose reductase activity in a partially purified bovine lens preparationChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Ep811-Cnrs

Curated by ChEMBL
LigandPNGBDBM50038839(2-(4-bromo-2-fluorobenzyl)-1H,2'H,5'H-spiro[isoqui...)
Affinity DataIC50:  23nMAssay Description:Compound was tested in vitro for inhibition of aldose reductase activity in partially purified bovine lens preparationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Ep811-Cnrs

Curated by ChEMBL
LigandPNGBDBM50038839(2-(4-bromo-2-fluorobenzyl)-1H,2'H,5'H-spiro[isoqui...)
Affinity DataIC50:  23nMAssay Description:In vitro inhibition of aldose reductase activity in a partially purified bovine lens preparationChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Ep811-Cnrs

Curated by ChEMBL
LigandPNGBDBM50038861(2-[4-(trifluoromethyl)benzyl]-1H,2'H,5'H-spiro[iso...)
Affinity DataIC50:  25nMAssay Description:In vitro inhibition of aldose reductase activity in a partially purified bovine lens preparationChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Ep811-Cnrs

Curated by ChEMBL
LigandPNGBDBM50038849(2-(3-methylbenzyl)-1H,2'H,5'H-spiro[isoquinoline-4...)
Affinity DataIC50:  25nMAssay Description:In vitro inhibition of aldose reductase activity in a partially purified bovine lens preparationChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Ep811-Cnrs

Curated by ChEMBL
LigandPNGBDBM50010062(CHEMBL84152 | [(2-Fluoro-6-methoxy-5-trifluorometh...)
Affinity DataIC50:  25nMAssay Description:Inhibition of aldose reductase activity of the compound was measured on partially purified bovine lens preparations incubated in presense of 50 mM gl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Ep811-Cnrs

Curated by ChEMBL
LigandPNGBDBM50038854(2-(4-methoxybenzyl)-1H,2'H,5'H-spiro[isoquinoline-...)
Affinity DataIC50:  25nMAssay Description:In vitro inhibition of aldose reductase activity in a partially purified bovine lens preparationChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Ep811-Cnrs

Curated by ChEMBL
LigandPNGBDBM50038846(6-fluoro-2-(5-trifluoromethylbenzo[d][1,3]thiazol-...)
Affinity DataIC50:  26nMAssay Description:In vitro inhibition of aldose reductase activity in a partially purified bovine lens preparationChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Ep811-Cnrs

Curated by ChEMBL
LigandPNGBDBM50038863(6-bromo-2-(4-bromo-2-fluorobenzyl)-7-methoxy-1H,2'...)
Affinity DataIC50:  28nMAssay Description:In vitro inhibition of aldose reductase activity in a partially purified bovine lens preparationChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Ep811-Cnrs

Curated by ChEMBL
LigandPNGBDBM50038845(2-(4-bromo-2-fluorobenzyl)-5-fluoro-6-methoxy-1H,2...)
Affinity DataIC50:  30nMAssay Description:In vitro inhibition of aldose reductase activity in a partially purified bovine lens preparationChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Ep811-Cnrs

Curated by ChEMBL
LigandPNGBDBM50038841(2-(4-bromo-2-fluorobenzyl)-6-chloro-1H,2'H,5'H-spi...)
Affinity DataIC50:  30nMAssay Description:In vitro inhibition of aldose reductase activity in a partially purified bovine lens preparationChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Ep811-Cnrs

Curated by ChEMBL
LigandPNGBDBM50038859((4S)-2-[(4-bromo-2-fluorophenyl)methyl]-6-fluoro-2...)
Affinity DataIC50:  32nMAssay Description:In vitro inhibition of aldose reductase activity in a partially purified bovine lens preparationChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Ep811-Cnrs

Curated by ChEMBL
LigandPNGBDBM50038848(2-(4-bromo-2-fluorobenzyl)-7-chloro-1H,2'H,5'H-spi...)
Affinity DataIC50:  33nMAssay Description:In vitro inhibition of aldose reductase activity in a partially purified bovine lens preparationChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Ep811-Cnrs

Curated by ChEMBL
LigandPNGBDBM16314(2-{[6-methoxy-5-(trifluoromethyl)naphthalen-1-yl]-...)
Affinity DataIC50:  33nMAssay Description:In vitro inhibition of aldose reductase activity in a partially purified bovine lens preparationChecked by AuthorMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Ep811-Cnrs

Curated by ChEMBL
LigandPNGBDBM16314(2-{[6-methoxy-5-(trifluoromethyl)naphthalen-1-yl]-...)
Affinity DataIC50:  33nMAssay Description:In vitro inhibition of aldose reductase in partially purified bovine lens preparation at a concentration of 10e -8M.More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Ep811-Cnrs

Curated by ChEMBL
LigandPNGBDBM16314(2-{[6-methoxy-5-(trifluoromethyl)naphthalen-1-yl]-...)
Affinity DataIC50:  34nMAssay Description:inhibition of aldose reductase activity of the compound was measured on partially purified bovine lens preparations incubated in presense of 50 mM gl...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Ep811-Cnrs

Curated by ChEMBL
LigandPNGBDBM16314(2-{[6-methoxy-5-(trifluoromethyl)naphthalen-1-yl]-...)
Affinity DataIC50:  35nMAssay Description:In vitro inhibition of aldose reductase from the partially purified bovine lensMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Ep811-Cnrs

Curated by ChEMBL
LigandPNGBDBM16314(2-{[6-methoxy-5-(trifluoromethyl)naphthalen-1-yl]-...)
Affinity DataIC50:  35nMAssay Description:In vitro inhibition of bovine lens aldose reductaseMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Ep811-Cnrs

Curated by ChEMBL
LigandPNGBDBM16314(2-{[6-methoxy-5-(trifluoromethyl)naphthalen-1-yl]-...)
Affinity DataIC50:  35nMAssay Description:Inhibition of bovine lens aldose reductase with DL-glyceraldehyde as substrateMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Ep811-Cnrs

Curated by ChEMBL
LigandPNGBDBM50038860(2-(4-bromo-2-fluorobenzyl)-7-methoxy-1H,2'H,5'H-sp...)
Affinity DataIC50:  37nMAssay Description:In vitro inhibition of aldose reductase activity in a partially purified bovine lens preparationChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Ep811-Cnrs

Curated by ChEMBL
LigandPNGBDBM50009777((ponalrestat)[3-(4-Bromo-2-fluoro-benzyl)-4-oxo-3,...)
Affinity DataIC50:  37nMAssay Description:In vitro Inhibition of aldose reductase was measured in isolated partially purified bovine lens preparations at 10e-7 M concentrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Ep811-Cnrs

Curated by ChEMBL
LigandPNGBDBM50038855(2-(4-bromo-2-fluorobenzyl)-6-(trifluoromethyl)-1H,...)
Affinity DataIC50:  38nMAssay Description:In vitro inhibition of aldose reductase activity in a partially purified bovine lens preparationChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Ep811-Cnrs

Curated by ChEMBL
LigandPNGBDBM50068074(CHEMBL142001 | {5-[1-(3-Chloro-naphthalen-2-yl)-me...)
Affinity DataIC50:  48nMAssay Description:Evaluated in vitro for the inhibition of Aldose reductase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Ep811-Cnrs

Curated by ChEMBL
LigandPNGBDBM50068075(CHEMBL336874 | {5-[1-(1-Bromo-naphthalen-2-yl)-met...)
Affinity DataIC50:  51nMAssay Description:Evaluated in vitro for the inhibition of Aldose reductase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Ep811-Cnrs

Curated by ChEMBL
LigandPNGBDBM50068073(CHEMBL143658 | {5-[1-(6-Methoxy-naphthalen-2-yl)-m...)
Affinity DataIC50:  67nMAssay Description:Evaluated in vitro for the inhibition of Aldose reductase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Ep811-Cnrs

Curated by ChEMBL
LigandPNGBDBM50334175(2-(2,4-dioxo-5-(4-phenoxybenzylidene)thiazolidin-3...)
Affinity DataIC50:  70nMAssay Description:Inhibition of bovine lens ALR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Ep811-Cnrs

Curated by ChEMBL
LigandPNGBDBM50068076(CHEMBL143933 | {5-[1-(1-Nitro-naphthalen-2-yl)-met...)
Affinity DataIC50:  79nMAssay Description:Evaluated in vitro for the inhibition of Aldose reductase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Ep811-Cnrs

Curated by ChEMBL
LigandPNGBDBM50068080(CHEMBL142615 | {5-[1-Naphthalen-2-yl-meth-(Z)-ylid...)
Affinity DataIC50:  96nMAssay Description:Evaluated in vitro for the inhibition of Aldose reductase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Ep811-Cnrs

Curated by ChEMBL
LigandPNGBDBM16314(2-{[6-methoxy-5-(trifluoromethyl)naphthalen-1-yl]-...)
Affinity DataIC50:  96nMAssay Description:Evaluated for inhibition of Aldose reductase 2More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Ep811-Cnrs

Curated by ChEMBL
LigandPNGBDBM50437452(CHEMBL2409349)
Affinity DataIC50:  99nMAssay Description:Inhibition of bovine lens aldose reductase using DL-glyceraldehyde as substrate assessed as NADPH oxidation measured for 10 mins by spectrophotometri...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Ep811-Cnrs

Curated by ChEMBL
LigandPNGBDBM50226988(CHEMBL81536)
Affinity DataIC50: <100nMAssay Description:In vitro inhibition of partially purified calf lens aldose reductase; value ranges from 10E-5 to 10E-6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Ep811-Cnrs

Curated by ChEMBL
LigandPNGBDBM50022499(7-methoxyspiro[3,4-dihydro-2H-benzo[h]chromene-4,4...)
Affinity DataIC50:  100nMAssay Description:In vitro inhibition of partially purified calf lens aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Ep811-Cnrs

Curated by ChEMBL
LigandPNGBDBM50022415(6-chloro-(4'S)-spiro[3,4-dihydro-2H-chromene-4,5'-...)
Affinity DataIC50:  100nMAssay Description:In vitro inhibition of partially purified calf lens aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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