Target (Institution) | Ligand | Target Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ALK tyrosine kinase receptor (R1275Q) (Homo sapiens (human)) | BDBM199945![]() (US9226923, 3) | PDB GoogleScholar AffyNet ![]() | Purchase PC cid PC sid UniChem AffyNet ![]() | US Patent | n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Nanjing Allgen Pharma Co. Ltd. US Patent | Assay Description The inhibitory activities of compounds of Formula I were assay at Reaction Biology Corporation, One Great Valley Parkway, Malvern, Pa., USA. Human ... | US Patent US9226923 (2016) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ALK tyrosine kinase receptor (R1275Q) (Homo sapiens (human)) | BDBM50306682![]() ((R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1...) | PDB GoogleScholar AffyNet ![]() | Purchase CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars AffyNet ![]() | PDB US Patent | n/a | n/a | 2.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Nanjing Allgen Pharma Co. Ltd. US Patent | Assay Description The inhibitory activities of compounds of Formula I were assay at Reaction Biology Corporation, One Great Valley Parkway, Malvern, Pa., USA. Human ... | US Patent US9226923 (2016) | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) |