Compile Data Set for Download or QSAR
maximum 50k data
Found 178 of ic50 data for polymerid = 8458
TargetProprotein convertase subtilisin/kexin type 9(Homo sapiens (Human))
Lauren Mccallister

Curated by ChEMBL
LigandPNGBDBM50543439(CHEMBL4642977)
Affinity DataIC50:  0.152nMAssay Description:Inhibition of human PCSK9 by Alexa Fluor 647 staining based TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProprotein convertase subtilisin/kexin type 9(Homo sapiens (Human))
Lauren Mccallister

Curated by ChEMBL
LigandPNGBDBM50543440(CHEMBL4635142)
Affinity DataIC50:  0.327nMAssay Description:Inhibition of human PCSK9 by Alexa Fluor 647 staining based TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProprotein convertase subtilisin/kexin type 9(Homo sapiens (Human))
Lauren Mccallister

Curated by ChEMBL
LigandPNGBDBM50543441(CHEMBL4642595)
Affinity DataIC50:  0.438nMAssay Description:Inhibition of human PCSK9 by Alexa Fluor 647 staining based TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProprotein convertase subtilisin/kexin type 9(Homo sapiens (Human))
Lauren Mccallister

Curated by ChEMBL
LigandPNGBDBM50543444(CHEMBL4641251)
Affinity DataIC50:  0.570nMAssay Description:Inhibition of human PCSK9 by Alexa Fluor 647 staining based TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProprotein convertase subtilisin/kexin type 9(Homo sapiens (Human))
Lauren Mccallister

Curated by ChEMBL
LigandPNGBDBM50543442(CHEMBL4645450)
Affinity DataIC50:  0.850nMAssay Description:Inhibition of human PCSK9 by Alexa Fluor 647 staining based TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProprotein convertase subtilisin/kexin type 9(Homo sapiens (Human))
Lauren Mccallister

Curated by ChEMBL
LigandPNGBDBM50543443(CHEMBL4638184)
Affinity DataIC50:  0.930nMAssay Description:Inhibition of human PCSK9 by Alexa Fluor 647 staining based TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProprotein convertase subtilisin/kexin type 9(Homo sapiens (Human))
Lauren Mccallister

Curated by ChEMBL
LigandPNGBDBM50535693(CHEMBL4572783)
Affinity DataIC50:  202nMAssay Description:Inhibition of human PCSK9 in HepG2 cells incubated for 24 hrs followed by medium replenishment and measured after 24 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProprotein convertase subtilisin/kexin type 9(Homo sapiens (Human))
Lauren Mccallister

Curated by ChEMBL
LigandPNGBDBM50535683(CHEMBL4549362)
Affinity DataIC50:  250nMAssay Description:Inhibition of human PCSK9 in HepG2 cells incubated for 48 hrs by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProprotein convertase subtilisin/kexin type 9(Homo sapiens (Human))
Lauren Mccallister

Curated by ChEMBL
LigandPNGBDBM50535686(CHEMBL4562557)
Affinity DataIC50:  300nMAssay Description:Inhibition of human PCSK9 in HepG2 cells incubated for 48 hrs by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProprotein convertase subtilisin/kexin type 9(Homo sapiens (Human))
Lauren Mccallister

Curated by ChEMBL
LigandPNGBDBM50582758(CHEMBL5085487)
Affinity DataIC50:  424nMAssay Description:Inhibition of human PCSK9More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProprotein convertase subtilisin/kexin type 9(Homo sapiens (Human))
Lauren Mccallister

Curated by ChEMBL
LigandPNGBDBM200316(US9227956, 1)
Affinity DataIC50:  440nMAssay Description:In order to eliminate the permeability barrier inherent to the WT7 and SCHH cell-based assays a cell-free system was also established to access compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProprotein convertase subtilisin/kexin type 9(Homo sapiens (Human))
Lauren Mccallister

Curated by ChEMBL
LigandPNGBDBM50520947(CHEMBL4458097)
Affinity DataIC50:  500nMAssay Description:Inhibition of His-tagged PCSK9 (unknown origin) binding to recombinant LDLR-AB domain (unknown origin) by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProprotein convertase subtilisin/kexin type 9(Homo sapiens (Human))
Lauren Mccallister

Curated by ChEMBL
LigandPNGBDBM200332(US9227956, 16)
Affinity DataIC50:  520nMAssay Description:In order to eliminate the permeability barrier inherent to the WT7 and SCHH cell-based assays a cell-free system was also established to access compo...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProprotein convertase subtilisin/kexin type 9(Homo sapiens (Human))
Lauren Mccallister

Curated by ChEMBL
LigandPNGBDBM200354(US9227956, 38 | US9227956, 39)
Affinity DataIC50:  592nMAssay Description:In order to eliminate the permeability barrier inherent to the WT7 and SCHH cell-based assays a cell-free system was also established to access compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProprotein convertase subtilisin/kexin type 9(Homo sapiens (Human))
Lauren Mccallister

Curated by ChEMBL
LigandPNGBDBM200325(US9227956, 10)
Affinity DataIC50:  640nMAssay Description:In order to eliminate the permeability barrier inherent to the WT7 and SCHH cell-based assays a cell-free system was also established to access compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProprotein convertase subtilisin/kexin type 9(Homo sapiens (Human))
Lauren Mccallister

Curated by ChEMBL
LigandPNGBDBM200317(US9227956, 2)
Affinity DataIC50:  690nMAssay Description:In order to eliminate the permeability barrier inherent to the WT7 and SCHH cell-based assays a cell-free system was also established to access compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProprotein convertase subtilisin/kexin type 9(Homo sapiens (Human))
Lauren Mccallister

Curated by ChEMBL
LigandPNGBDBM200332(US9227956, 16)
Affinity DataIC50:  750nMAssay Description:Inhibition of PCSK9 translation in human THP-1 cells by AlphaLISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProprotein convertase subtilisin/kexin type 9(Homo sapiens (Human))
Lauren Mccallister

Curated by ChEMBL
LigandPNGBDBM217361(Pep2-2 | TVFTSWEEYLLWV)
Affinity DataIC50:  760nMAssay Description:For the peptide affinity determinations, biotinylated PCSK9 was immobilized to NeutrAvidin-coated MaxiSorp Immuno-Plates and incubated with a mixture...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProprotein convertase subtilisin/kexin type 9(Homo sapiens (Human))
Lauren Mccallister

Curated by ChEMBL
LigandPNGBDBM200318(US9227956, 3)
Affinity DataIC50:  780nMAssay Description:Inhibition of PCSK9 translation in human THP-1 cells by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProprotein convertase subtilisin/kexin type 9(Homo sapiens (Human))
Lauren Mccallister

Curated by ChEMBL
LigandPNGBDBM200328(US9227956, 13)
Affinity DataIC50:  800nMAssay Description:In order to eliminate the permeability barrier inherent to the WT7 and SCHH cell-based assays a cell-free system was also established to access compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProprotein convertase subtilisin/kexin type 9(Homo sapiens (Human))
Lauren Mccallister

Curated by ChEMBL
LigandPNGBDBM200318(US9227956, 3)
Affinity DataIC50:  800nMAssay Description:An in-vitro AlphaLISA assay (Perkin Elmer) was developed in order to quantitate the level of PCSK9 secreted into the cell culture media following com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProprotein convertase subtilisin/kexin type 9(Homo sapiens (Human))
Lauren Mccallister

Curated by ChEMBL
LigandPNGBDBM200332(US9227956, 16)
Affinity DataIC50:  800nMAssay Description:An in-vitro AlphaLISA assay (Perkin Elmer) was developed in order to quantitate the level of PCSK9 secreted into the cell culture media following com...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProprotein convertase subtilisin/kexin type 9(Homo sapiens (Human))
Lauren Mccallister

Curated by ChEMBL
LigandPNGBDBM50535688(CHEMBL4585306)
Affinity DataIC50:  900nMAssay Description:Inhibition of human PCSK9 in HepG2 cells incubated for 48 hrs by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProprotein convertase subtilisin/kexin type 9(Homo sapiens (Human))
Lauren Mccallister

Curated by ChEMBL
LigandPNGBDBM50275487(CHEMBL4126496)
Affinity DataIC50:  900nMAssay Description:Inhibition of PCSK9 translation in human THP-1 cells by AlphaLISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProprotein convertase subtilisin/kexin type 9(Homo sapiens (Human))
Lauren Mccallister

Curated by ChEMBL
LigandPNGBDBM50535690(CHEMBL4528279)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of human PCSK9 in HepG2 cells incubated for 48 hrs by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProprotein convertase subtilisin/kexin type 9(Homo sapiens (Human))
Lauren Mccallister

Curated by ChEMBL
LigandPNGBDBM50582341(CHEMBL5092750)
Affinity DataIC50:  1.26E+3nMAssay Description:Inhibition of tEGF-A[HA] binding to biotinylated human PCSK9 incubated for 2 hrs by ELISA based competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProprotein convertase subtilisin/kexin type 9(Homo sapiens (Human))
Lauren Mccallister

Curated by ChEMBL
LigandPNGBDBM50275430(CHEMBL4130157)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of PCSK9 translation in human THP-1 cells by AlphaLISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProprotein convertase subtilisin/kexin type 9(Homo sapiens (Human))
Lauren Mccallister

Curated by ChEMBL
LigandPNGBDBM50535687(CHEMBL4435394)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of human PCSK9 in HepG2 cells incubated for 48 hrs by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProprotein convertase subtilisin/kexin type 9(Homo sapiens (Human))
Lauren Mccallister

Curated by ChEMBL
LigandPNGBDBM217366(Pep2-8 | TVFTSWEEYLDWV)
Affinity DataIC50:  1.40E+3nMAssay Description:For the peptide affinity determinations, biotinylated PCSK9 was immobilized to NeutrAvidin-coated MaxiSorp Immuno-Plates and incubated with a mixture...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProprotein convertase subtilisin/kexin type 9(Homo sapiens (Human))
Lauren Mccallister

Curated by ChEMBL
LigandPNGBDBM200320(US9227956, 5)
Affinity DataIC50:  1.50E+3nMAssay Description:An in-vitro AlphaLISA assay (Perkin Elmer) was developed in order to quantitate the level of PCSK9 secreted into the cell culture media following com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProprotein convertase subtilisin/kexin type 9(Homo sapiens (Human))
Lauren Mccallister

Curated by ChEMBL
LigandPNGBDBM200321(US9227956, 6)
Affinity DataIC50:  1.50E+3nMAssay Description:An in-vitro AlphaLISA assay (Perkin Elmer) was developed in order to quantitate the level of PCSK9 secreted into the cell culture media following com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProprotein convertase subtilisin/kexin type 9(Homo sapiens (Human))
Lauren Mccallister

Curated by ChEMBL
LigandPNGBDBM200325(US9227956, 10)
Affinity DataIC50:  1.50E+3nMAssay Description:An in-vitro AlphaLISA assay (Perkin Elmer) was developed in order to quantitate the level of PCSK9 secreted into the cell culture media following com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProprotein convertase subtilisin/kexin type 9(Homo sapiens (Human))
Lauren Mccallister

Curated by ChEMBL
LigandPNGBDBM50535689(CHEMBL4462933)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of human PCSK9 in HepG2 cells incubated for 48 hrs by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProprotein convertase subtilisin/kexin type 9(Homo sapiens (Human))
Lauren Mccallister

Curated by ChEMBL
LigandPNGBDBM50460548(CHEMBL4227596)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of PCSK9 binding to LDLR in human HuH7 cells after 5 hrs by On-cell Western assayMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetProprotein convertase subtilisin/kexin type 9(Homo sapiens (Human))
Lauren Mccallister

Curated by ChEMBL
LigandPNGBDBM50582757(CHEMBL5078995)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of human PCSK9More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProprotein convertase subtilisin/kexin type 9(Homo sapiens (Human))
Lauren Mccallister

Curated by ChEMBL
LigandPNGBDBM200327(US9227956, 12)
Affinity DataIC50:  1.70E+3nMAssay Description:In order to eliminate the permeability barrier inherent to the WT7 and SCHH cell-based assays a cell-free system was also established to access compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProprotein convertase subtilisin/kexin type 9(Homo sapiens (Human))
Lauren Mccallister

Curated by ChEMBL
LigandPNGBDBM50581623(CHEMBL5088467)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of PCSK9 translation in human THP-1 cells by AlphaLISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProprotein convertase subtilisin/kexin type 9(Homo sapiens (Human))
Lauren Mccallister

Curated by ChEMBL
LigandPNGBDBM200317(US9227956, 2)
Affinity DataIC50:  1.70E+3nMAssay Description:An in-vitro AlphaLISA assay (Perkin Elmer) was developed in order to quantitate the level of PCSK9 secreted into the cell culture media following com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProprotein convertase subtilisin/kexin type 9(Homo sapiens (Human))
Lauren Mccallister

Curated by ChEMBL
LigandPNGBDBM200321(US9227956, 6)
Affinity DataIC50:  1.70E+3nMAssay Description:In order to eliminate the permeability barrier inherent to the WT7 and SCHH cell-based assays a cell-free system was also established to access compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProprotein convertase subtilisin/kexin type 9(Homo sapiens (Human))
Lauren Mccallister

Curated by ChEMBL
LigandPNGBDBM200324(US9227956, 9)
Affinity DataIC50:  1.80E+3nMAssay Description:An in-vitro AlphaLISA assay (Perkin Elmer) was developed in order to quantitate the level of PCSK9 secreted into the cell culture media following com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProprotein convertase subtilisin/kexin type 9(Homo sapiens (Human))
Lauren Mccallister

Curated by ChEMBL
LigandPNGBDBM200326(US9227956, 11)
Affinity DataIC50:  2.10E+3nMAssay Description:In order to eliminate the permeability barrier inherent to the WT7 and SCHH cell-based assays a cell-free system was also established to access compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProprotein convertase subtilisin/kexin type 9(Homo sapiens (Human))
Lauren Mccallister

Curated by ChEMBL
LigandPNGBDBM200354(US9227956, 38 | US9227956, 39)
Affinity DataIC50:  2.19E+3nMAssay Description:In order to eliminate the permeability barrier inherent to the WT7 and SCHH cell-based assays a cell-free system was also established to access compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProprotein convertase subtilisin/kexin type 9(Homo sapiens (Human))
Lauren Mccallister

Curated by ChEMBL
LigandPNGBDBM200316(US9227956, 1)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of PCSK9 translation in human THP-1 cells by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProprotein convertase subtilisin/kexin type 9(Homo sapiens (Human))
Lauren Mccallister

Curated by ChEMBL
LigandPNGBDBM50535691(CHEMBL4461546)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of human PCSK9 in HepG2 cells incubated for 48 hrs by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProprotein convertase subtilisin/kexin type 9(Homo sapiens (Human))
Lauren Mccallister

Curated by ChEMBL
LigandPNGBDBM50535685(CHEMBL4531399)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of human PCSK9 in HepG2 cells incubated for 48 hrs by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProprotein convertase subtilisin/kexin type 9(Homo sapiens (Human))
Lauren Mccallister

Curated by ChEMBL
LigandPNGBDBM200328(US9227956, 13)
Affinity DataIC50:  2.30E+3nMAssay Description:An in-vitro AlphaLISA assay (Perkin Elmer) was developed in order to quantitate the level of PCSK9 secreted into the cell culture media following com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProprotein convertase subtilisin/kexin type 9(Homo sapiens (Human))
Lauren Mccallister

Curated by ChEMBL
LigandPNGBDBM200328(US9227956, 13)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of PCSK9 translation in human THP-1 cells by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProprotein convertase subtilisin/kexin type 9(Homo sapiens (Human))
Lauren Mccallister

Curated by ChEMBL
LigandPNGBDBM50275434(CHEMBL4127458)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of PCSK9 translation in human THP-1 cells by AlphaLISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProprotein convertase subtilisin/kexin type 9(Homo sapiens (Human))
Lauren Mccallister

Curated by ChEMBL
LigandPNGBDBM50535692(CHEMBL4545753)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of human PCSK9 in HepG2 cells incubated for 48 hrs by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProprotein convertase subtilisin/kexin type 9(Homo sapiens (Human))
Lauren Mccallister

Curated by ChEMBL
LigandPNGBDBM200341(US9227956, 25)
Affinity DataIC50:  2.97E+3nMAssay Description:In order to eliminate the permeability barrier inherent to the WT7 and SCHH cell-based assays a cell-free system was also established to access compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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