Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
PAK1 (Homo sapiens (Human)) | BDBM50181451![]() (CHEMBL3818265) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.950 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shanghai Chempartner Inc. Curated by ChEMBL | Assay Description Inhibition of human recombinant N-terminal 6-His-tagged PAK1 kinase domain (249 to 545 residues) expressed in Escherichia coli BL21(DE3) assessed as ... | J Med Chem 59: 5520-41 (2016) Article DOI: 10.1021/acs.jmedchem.6b00638 BindingDB Entry DOI: 10.7270/Q23X88KT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
PAK1 (Homo sapiens (Human)) | BDBM50148928![]() (CHEMBL3770909) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech Curated by ChEMBL | Assay Description Inhibition of human recombinant PAK1 kinase domain using coumarin/fluorescein-labeled FRET peptide as substrate preincubated for 10 mins followed by ... | ACS Med Chem Lett 6: 1241-6 (2015) Article DOI: 10.1021/acsmedchemlett.5b00398 BindingDB Entry DOI: 10.7270/Q2MP554V | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
PAK1 (Homo sapiens (Human)) | BDBM50148920![]() (CHEMBL3769478) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech Curated by ChEMBL | Assay Description Inhibition of human recombinant PAK1 kinase domain using coumarin/fluorescein-labeled FRET peptide as substrate preincubated for 10 mins followed by ... | ACS Med Chem Lett 6: 1241-6 (2015) Article DOI: 10.1021/acsmedchemlett.5b00398 BindingDB Entry DOI: 10.7270/Q2MP554V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
PAK1 (Homo sapiens (Human)) | BDBM50148927![]() (CHEMBL3770588) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Patents Similars | Article PubMed | 2.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech Curated by ChEMBL | Assay Description Inhibition of human recombinant PAK1 kinase domain using coumarin/fluorescein-labeled FRET peptide as substrate preincubated for 10 mins followed by ... | ACS Med Chem Lett 6: 1241-6 (2015) Article DOI: 10.1021/acsmedchemlett.5b00398 BindingDB Entry DOI: 10.7270/Q2MP554V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
PAK1 (Homo sapiens (Human)) | BDBM50181449![]() (CHEMBL3817856) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shanghai Chempartner Inc. Curated by ChEMBL | Assay Description Inhibition of human recombinant N-terminal 6-His-tagged PAK1 kinase domain (249 to 545 residues) expressed in Escherichia coli BL21(DE3) assessed as ... | J Med Chem 59: 5520-41 (2016) Article DOI: 10.1021/acs.jmedchem.6b00638 BindingDB Entry DOI: 10.7270/Q23X88KT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
PAK1 (Homo sapiens (Human)) | BDBM50182295![]() (CHEMBL3818046) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | 3.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shanghai Chempartner Inc. Curated by ChEMBL | Assay Description Inhibition of human recombinant N-terminal 6-His-tagged PAK1 kinase domain (249 to 545 residues) expressed in Escherichia coli BL21(DE3) assessed as ... | J Med Chem 59: 5520-41 (2016) Article DOI: 10.1021/acs.jmedchem.6b00638 BindingDB Entry DOI: 10.7270/Q23X88KT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
PAK1 (Homo sapiens (Human)) | BDBM50182290![]() (CHEMBL3819356) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 3.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shanghai Chempartner Inc. Curated by ChEMBL | Assay Description Inhibition of human recombinant N-terminal 6-His-tagged PAK1 kinase domain (249 to 545 residues) expressed in Escherichia coli BL21(DE3) assessed as ... | J Med Chem 59: 5520-41 (2016) Article DOI: 10.1021/acs.jmedchem.6b00638 BindingDB Entry DOI: 10.7270/Q23X88KT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
PAK1 (Homo sapiens (Human)) | BDBM50148921![]() (CHEMBL3770443) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 3.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shanghai Chempartner Inc. Curated by ChEMBL | Assay Description Inhibition of human recombinant N-terminal 6-His-tagged PAK1 kinase domain (249 to 545 residues) expressed in Escherichia coli BL21(DE3) assessed as ... | J Med Chem 59: 5520-41 (2016) Article DOI: 10.1021/acs.jmedchem.6b00638 BindingDB Entry DOI: 10.7270/Q23X88KT | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
PAK1 (Homo sapiens (Human)) | BDBM50148921![]() (CHEMBL3770443) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 3.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech Curated by ChEMBL | Assay Description Inhibition of human recombinant PAK1 kinase domain using coumarin/fluorescein-labeled FRET peptide as substrate preincubated for 10 mins followed by ... | ACS Med Chem Lett 6: 1241-6 (2015) Article DOI: 10.1021/acsmedchemlett.5b00398 BindingDB Entry DOI: 10.7270/Q2MP554V | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
PAK1 (Homo sapiens (Human)) | BDBM50096231![]() (CHEMBL3580975) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shanghai Chempartner Inc. Curated by ChEMBL | Assay Description Inhibition of human recombinant PAK1 kinase domain using coumarin/fluorescein-labeled FRET peptide as substrate assessed as substrate phosphorylation... | J Med Chem 58: 5121-36 (2015) Article DOI: 10.1021/acs.jmedchem.5b00572 BindingDB Entry DOI: 10.7270/Q2DV1MN9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
PAK1 (Homo sapiens (Human)) | BDBM50185825![]() (CHEMBL3824224) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech Curated by ChEMBL | Assay Description Inhibition of recombinant human GST-tagged PAK1 kinase domain expressed in baculovirus expression system assessed as suppression of phosphorylation o... | Bioorg Med Chem Lett 26: 3518-24 (2016) Article DOI: 10.1016/j.bmcl.2016.06.031 BindingDB Entry DOI: 10.7270/Q2KK9DQJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
PAK1 (Homo sapiens (Human)) | BDBM50434331![]() (CHEMBL2386717) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 4.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human recombinant GST-tagged PAK1 kinase domain-mediated 5FAM-RRRLSFAEPG phosphorylation expressed in Sf9 cells preincubated for 10 min... | Citation and Details Article DOI: 10.1021/ml400101g BindingDB Entry DOI: 10.7270/Q2X068DZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
PAK1 (Homo sapiens (Human)) | BDBM50148919![]() (CHEMBL3770363) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Patents Similars | Article PubMed | 4.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech Curated by ChEMBL | Assay Description Inhibition of human recombinant PAK1 kinase domain using coumarin/fluorescein-labeled FRET peptide as substrate preincubated for 10 mins followed by ... | ACS Med Chem Lett 6: 1241-6 (2015) Article DOI: 10.1021/acsmedchemlett.5b00398 BindingDB Entry DOI: 10.7270/Q2MP554V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
PAK1 (Homo sapiens (Human)) | BDBM50181450![]() (CHEMBL3818828) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 4.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shanghai Chempartner Inc. Curated by ChEMBL | Assay Description Inhibition of human recombinant N-terminal 6-His-tagged PAK1 kinase domain (249 to 545 residues) expressed in Escherichia coli BL21(DE3) assessed as ... | J Med Chem 59: 5520-41 (2016) Article DOI: 10.1021/acs.jmedchem.6b00638 BindingDB Entry DOI: 10.7270/Q23X88KT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
PAK1 (Homo sapiens (Human)) | BDBM50182287![]() (CHEMBL3818592) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 4.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shanghai Chempartner Inc. Curated by ChEMBL | Assay Description Inhibition of human recombinant N-terminal 6-His-tagged PAK1 kinase domain (249 to 545 residues) expressed in Escherichia coli BL21(DE3) assessed as ... | J Med Chem 59: 5520-41 (2016) Article DOI: 10.1021/acs.jmedchem.6b00638 BindingDB Entry DOI: 10.7270/Q23X88KT | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
PAK1 (Homo sapiens (Human)) | BDBM50096231![]() (CHEMBL3580975) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech Curated by ChEMBL | Assay Description Inhibition of PAK1 (unknown origin) | ACS Med Chem Lett 6: 711-5 (2015) Article DOI: 10.1021/acsmedchemlett.5b00151 BindingDB Entry DOI: 10.7270/Q24J0GWT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
PAK1 (Homo sapiens (Human)) | BDBM50097128![]() (CHEMBL3580976) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shanghai Chempartner Inc. Curated by ChEMBL | Assay Description Inhibition of human recombinant PAK1 kinase domain using coumarin/fluorescein-labeled FRET peptide as substrate assessed as substrate phosphorylation... | J Med Chem 58: 5121-36 (2015) Article DOI: 10.1021/acs.jmedchem.5b00572 BindingDB Entry DOI: 10.7270/Q2DV1MN9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
PAK1 (Homo sapiens (Human)) | BDBM50097135![]() (CHEMBL3580974) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shanghai Chempartner Inc. Curated by ChEMBL | Assay Description Inhibition of human recombinant PAK1 kinase domain using coumarin/fluorescein-labeled FRET peptide as substrate assessed as substrate phosphorylation... | J Med Chem 58: 5121-36 (2015) Article DOI: 10.1021/acs.jmedchem.5b00572 BindingDB Entry DOI: 10.7270/Q2DV1MN9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
PAK1 (Homo sapiens (Human)) | BDBM50185823![]() (CHEMBL3823612) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech Curated by ChEMBL | Assay Description Inhibition of recombinant human GST-tagged PAK1 kinase domain expressed in baculovirus expression system assessed as suppression of phosphorylation o... | Bioorg Med Chem Lett 26: 3518-24 (2016) Article DOI: 10.1016/j.bmcl.2016.06.031 BindingDB Entry DOI: 10.7270/Q2KK9DQJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
PAK1 (Homo sapiens (Human)) | BDBM50434333![]() (CHEMBL2386718) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article PubMed | 5.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human recombinant GST-tagged PAK1 kinase domain-mediated 5FAM-RRRLSFAEPG phosphorylation expressed in Sf9 cells preincubated for 10 min... | Citation and Details Article DOI: 10.1021/ml400101g BindingDB Entry DOI: 10.7270/Q2X068DZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
PAK1 (Homo sapiens (Human)) | BDBM50182399![]() (CHEMBL3818479) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Patents Similars | Article PubMed | 5.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shanghai Chempartner Inc. Curated by ChEMBL | Assay Description Inhibition of human recombinant N-terminal 6-His-tagged PAK1 kinase domain (249 to 545 residues) expressed in Escherichia coli BL21(DE3) assessed as ... | J Med Chem 59: 5520-41 (2016) Article DOI: 10.1021/acs.jmedchem.6b00638 BindingDB Entry DOI: 10.7270/Q23X88KT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
PAK1 (Homo sapiens (Human)) | BDBM50182405![]() (CHEMBL3818016) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 5.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shanghai Chempartner Inc. Curated by ChEMBL | Assay Description Inhibition of human recombinant N-terminal 6-His-tagged PAK1 kinase domain (249 to 545 residues) expressed in Escherichia coli BL21(DE3) assessed as ... | J Med Chem 59: 5520-41 (2016) Article DOI: 10.1021/acs.jmedchem.6b00638 BindingDB Entry DOI: 10.7270/Q23X88KT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
PAK1 (Homo sapiens (Human)) | BDBM50185827![]() (CHEMBL3823523) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech Curated by ChEMBL | Assay Description Inhibition of recombinant human GST-tagged PAK1 kinase domain expressed in baculovirus expression system assessed as suppression of phosphorylation o... | Bioorg Med Chem Lett 26: 3518-24 (2016) Article DOI: 10.1016/j.bmcl.2016.06.031 BindingDB Entry DOI: 10.7270/Q2KK9DQJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
PAK1 (Homo sapiens (Human)) | BDBM50148930![]() (CHEMBL3769748) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Patents Similars | Article PubMed | 6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech Curated by ChEMBL | Assay Description Inhibition of human recombinant PAK1 kinase domain using coumarin/fluorescein-labeled FRET peptide as substrate preincubated for 10 mins followed by ... | ACS Med Chem Lett 6: 1241-6 (2015) Article DOI: 10.1021/acsmedchemlett.5b00398 BindingDB Entry DOI: 10.7270/Q2MP554V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
PAK1 (Homo sapiens (Human)) | BDBM50148929![]() (CHEMBL3770369) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Patents Similars | Article PubMed | 6.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech Curated by ChEMBL | Assay Description Inhibition of human recombinant PAK1 kinase domain using coumarin/fluorescein-labeled FRET peptide as substrate preincubated for 10 mins followed by ... | ACS Med Chem Lett 6: 1241-6 (2015) Article DOI: 10.1021/acsmedchemlett.5b00398 BindingDB Entry DOI: 10.7270/Q2MP554V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
PAK1 (Homo sapiens (Human)) | BDBM50182294![]() (CHEMBL3817984) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 6.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shanghai Chempartner Inc. Curated by ChEMBL | Assay Description Inhibition of human recombinant N-terminal 6-His-tagged PAK1 kinase domain (249 to 545 residues) expressed in Escherichia coli BL21(DE3) assessed as ... | J Med Chem 59: 5520-41 (2016) Article DOI: 10.1021/acs.jmedchem.6b00638 BindingDB Entry DOI: 10.7270/Q23X88KT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
PAK1 (Homo sapiens (Human)) | BDBM50182288![]() (CHEMBL3818432) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 6.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shanghai Chempartner Inc. Curated by ChEMBL | Assay Description Inhibition of human recombinant N-terminal 6-His-tagged PAK1 kinase domain (249 to 545 residues) expressed in Escherichia coli BL21(DE3) assessed as ... | J Med Chem 59: 5520-41 (2016) Article DOI: 10.1021/acs.jmedchem.6b00638 BindingDB Entry DOI: 10.7270/Q23X88KT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
PAK1 (Homo sapiens (Human)) | BDBM50434332![]() (CHEMBL2386716) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article PubMed | 6.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human recombinant GST-tagged PAK1 kinase domain-mediated 5FAM-RRRLSFAEPG phosphorylation expressed in Sf9 cells preincubated for 10 min... | Citation and Details Article DOI: 10.1021/ml400101g BindingDB Entry DOI: 10.7270/Q2X068DZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
PAK1 (Homo sapiens (Human)) | BDBM50148926![]() (CHEMBL3769456) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Patents Similars | Article PubMed | 7.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech Curated by ChEMBL | Assay Description Inhibition of human recombinant PAK1 kinase domain using coumarin/fluorescein-labeled FRET peptide as substrate preincubated for 10 mins followed by ... | ACS Med Chem Lett 6: 1241-6 (2015) Article DOI: 10.1021/acsmedchemlett.5b00398 BindingDB Entry DOI: 10.7270/Q2MP554V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
PAK1 (Homo sapiens (Human)) | BDBM50148918![]() (CHEMBL3769552) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 7.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech Curated by ChEMBL | Assay Description Inhibition of human recombinant PAK1 kinase domain using coumarin/fluorescein-labeled FRET peptide as substrate preincubated for 10 mins followed by ... | ACS Med Chem Lett 6: 1241-6 (2015) Article DOI: 10.1021/acsmedchemlett.5b00398 BindingDB Entry DOI: 10.7270/Q2MP554V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
PAK1 (Homo sapiens (Human)) | BDBM50182293![]() (CHEMBL3817890) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shanghai Chempartner Inc. Curated by ChEMBL | Assay Description Inhibition of human recombinant N-terminal 6-His-tagged PAK1 kinase domain (249 to 545 residues) expressed in Escherichia coli BL21(DE3) assessed as ... | J Med Chem 59: 5520-41 (2016) Article DOI: 10.1021/acs.jmedchem.6b00638 BindingDB Entry DOI: 10.7270/Q23X88KT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
PAK1 (Homo sapiens (Human)) | BDBM50148922![]() (CHEMBL3770295) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | 8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech Curated by ChEMBL | Assay Description Inhibition of human recombinant PAK1 kinase domain using coumarin/fluorescein-labeled FRET peptide as substrate preincubated for 10 mins followed by ... | ACS Med Chem Lett 6: 1241-6 (2015) Article DOI: 10.1021/acsmedchemlett.5b00398 BindingDB Entry DOI: 10.7270/Q2MP554V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
PAK1 (Homo sapiens (Human)) | BDBM50181448![]() (CHEMBL3818233) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 9 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shanghai Chempartner Inc. Curated by ChEMBL | Assay Description Inhibition of human recombinant N-terminal 6-His-tagged PAK1 kinase domain (249 to 545 residues) expressed in Escherichia coli BL21(DE3) assessed as ... | J Med Chem 59: 5520-41 (2016) Article DOI: 10.1021/acs.jmedchem.6b00638 BindingDB Entry DOI: 10.7270/Q23X88KT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
PAK1 (Homo sapiens (Human)) | BDBM50185828![]() (CHEMBL3824061) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 11 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech Curated by ChEMBL | Assay Description Inhibition of recombinant human GST-tagged PAK1 kinase domain expressed in baculovirus expression system assessed as suppression of phosphorylation o... | Bioorg Med Chem Lett 26: 3518-24 (2016) Article DOI: 10.1016/j.bmcl.2016.06.031 BindingDB Entry DOI: 10.7270/Q2KK9DQJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
PAK1 (Homo sapiens (Human)) | BDBM50181452![]() (CHEMBL3819118) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 11 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shanghai Chempartner Inc. Curated by ChEMBL | Assay Description Inhibition of human recombinant N-terminal 6-His-tagged PAK1 kinase domain (249 to 545 residues) expressed in Escherichia coli BL21(DE3) assessed as ... | J Med Chem 59: 5520-41 (2016) Article DOI: 10.1021/acs.jmedchem.6b00638 BindingDB Entry DOI: 10.7270/Q23X88KT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
PAK1 (Homo sapiens (Human)) | BDBM50182399![]() (CHEMBL3818479) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Patents Similars | Article PubMed | 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shanghai Chempartner Inc. Curated by ChEMBL | Assay Description Inhibition of human recombinant N-terminal 6-His-tagged PAK1 kinase domain (249 to 545 residues) expressed in Escherichia coli BL21(DE3) assessed as ... | J Med Chem 59: 5520-41 (2016) Article DOI: 10.1021/acs.jmedchem.6b00638 BindingDB Entry DOI: 10.7270/Q23X88KT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
PAK1 (Homo sapiens (Human)) | BDBM50097134![]() (CHEMBL3580972) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shanghai Chempartner Inc. Curated by ChEMBL | Assay Description Inhibition of human recombinant PAK1 kinase domain using coumarin/fluorescein-labeled FRET peptide as substrate assessed as substrate phosphorylation... | J Med Chem 58: 5121-36 (2015) Article DOI: 10.1021/acs.jmedchem.5b00572 BindingDB Entry DOI: 10.7270/Q2DV1MN9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
PAK1 (Homo sapiens (Human)) | BDBM50182297![]() (CHEMBL3818372) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shanghai Chempartner Inc. Curated by ChEMBL | Assay Description Inhibition of human recombinant N-terminal 6-His-tagged PAK1 kinase domain (249 to 545 residues) expressed in Escherichia coli BL21(DE3) assessed as ... | J Med Chem 59: 5520-41 (2016) Article DOI: 10.1021/acs.jmedchem.6b00638 BindingDB Entry DOI: 10.7270/Q23X88KT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
PAK1 (Homo sapiens (Human)) | BDBM50182292![]() (CHEMBL3818273) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shanghai Chempartner Inc. Curated by ChEMBL | Assay Description Inhibition of human recombinant N-terminal 6-His-tagged PAK1 kinase domain (249 to 545 residues) expressed in Escherichia coli BL21(DE3) assessed as ... | J Med Chem 59: 5520-41 (2016) Article DOI: 10.1021/acs.jmedchem.6b00638 BindingDB Entry DOI: 10.7270/Q23X88KT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
PAK1 (Homo sapiens (Human)) | BDBM101536![]() (CHEMBL3128043 | US8530494, 203 | US8530652, 114 | ...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 15 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech Curated by ChEMBL | Assay Description Binding affinity to N-terminal His-6-tagged recombinant human PAK1 using peptide substrate | J Med Chem 57: 1033-45 (2014) Article DOI: 10.1021/jm401768t BindingDB Entry DOI: 10.7270/Q2F47QNW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
PAK1 (Homo sapiens (Human)) | BDBM50096233![]() (CHEMBL3593824) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech Curated by ChEMBL | Assay Description Inhibition of PAK1 (unknown origin) | ACS Med Chem Lett 6: 711-5 (2015) Article DOI: 10.1021/acsmedchemlett.5b00151 BindingDB Entry DOI: 10.7270/Q24J0GWT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
PAK1 (Homo sapiens (Human)) | BDBM50182291![]() (CHEMBL3818138) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 17 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shanghai Chempartner Inc. Curated by ChEMBL | Assay Description Inhibition of human recombinant N-terminal 6-His-tagged PAK1 kinase domain (249 to 545 residues) expressed in Escherichia coli BL21(DE3) assessed as ... | J Med Chem 59: 5520-41 (2016) Article DOI: 10.1021/acs.jmedchem.6b00638 BindingDB Entry DOI: 10.7270/Q23X88KT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
PAK1 (Homo sapiens (Human)) | BDBM50096228![]() (CHEMBL3594175) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 18 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech Curated by ChEMBL | Assay Description Inhibition of PAK1 (unknown origin) | ACS Med Chem Lett 6: 711-5 (2015) Article DOI: 10.1021/acsmedchemlett.5b00151 BindingDB Entry DOI: 10.7270/Q24J0GWT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
PAK1 (Homo sapiens (Human)) | BDBM50185833![]() (CHEMBL3823457) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | 18 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech Curated by ChEMBL | Assay Description Inhibition of recombinant human GST-tagged PAK1 kinase domain expressed in baculovirus expression system assessed as suppression of phosphorylation o... | Bioorg Med Chem Lett 26: 3518-24 (2016) Article DOI: 10.1016/j.bmcl.2016.06.031 BindingDB Entry DOI: 10.7270/Q2KK9DQJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
PAK1 (Homo sapiens (Human)) | BDBM50096239![]() (CHEMBL3594180) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 18 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech Curated by ChEMBL | Assay Description Inhibition of PAK1 (unknown origin) | ACS Med Chem Lett 6: 711-5 (2015) Article DOI: 10.1021/acsmedchemlett.5b00151 BindingDB Entry DOI: 10.7270/Q24J0GWT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
PAK1 (Homo sapiens (Human)) | BDBM50097121![]() (CHEMBL3580954) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 18 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shanghai Chempartner Inc. Curated by ChEMBL | Assay Description Inhibition of human recombinant PAK1 kinase domain using coumarin/fluorescein-labeled FRET peptide as substrate assessed as substrate phosphorylation... | J Med Chem 58: 5121-36 (2015) Article DOI: 10.1021/acs.jmedchem.5b00572 BindingDB Entry DOI: 10.7270/Q2DV1MN9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
PAK1 (Homo sapiens (Human)) | BDBM50148923![]() (CHEMBL3770943) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 19 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech Curated by ChEMBL | Assay Description Inhibition of human recombinant PAK1 kinase domain using coumarin/fluorescein-labeled FRET peptide as substrate preincubated for 10 mins followed by ... | ACS Med Chem Lett 6: 1241-6 (2015) Article DOI: 10.1021/acsmedchemlett.5b00398 BindingDB Entry DOI: 10.7270/Q2MP554V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
PAK1 (Homo sapiens (Human)) | BDBM50097144![]() (CHEMBL3580963) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 21 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shanghai Chempartner Inc. Curated by ChEMBL | Assay Description Inhibition of human recombinant PAK1 kinase domain using coumarin/fluorescein-labeled FRET peptide as substrate assessed as substrate phosphorylation... | J Med Chem 58: 5121-36 (2015) Article DOI: 10.1021/acs.jmedchem.5b00572 BindingDB Entry DOI: 10.7270/Q2DV1MN9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
PAK1 (Homo sapiens (Human)) | BDBM50148931![]() (CHEMBL3770186) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 22 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech Curated by ChEMBL | Assay Description Inhibition of human recombinant PAK1 kinase domain using coumarin/fluorescein-labeled FRET peptide as substrate preincubated for 10 mins followed by ... | ACS Med Chem Lett 6: 1241-6 (2015) Article DOI: 10.1021/acsmedchemlett.5b00398 BindingDB Entry DOI: 10.7270/Q2MP554V | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
PAK1 (Homo sapiens (Human)) | BDBM50182402![]() (CHEMBL3819447) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 22 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shanghai Chempartner Inc. Curated by ChEMBL | Assay Description Inhibition of human recombinant N-terminal 6-His-tagged PAK1 kinase domain (249 to 545 residues) expressed in Escherichia coli BL21(DE3) assessed as ... | J Med Chem 59: 5520-41 (2016) Article DOI: 10.1021/acs.jmedchem.6b00638 BindingDB Entry DOI: 10.7270/Q23X88KT | |||||||||||
More data for this Ligand-Target Pair |
Displayed 1 to 50 (of 127 total ) | Next | Last >> |