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Compile Data Set for Download or QSAR

Found 268 hits of ic50 data for polymerid = 989   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Plasmepsin 2


(Plasmodium falciparum)
BDBM50377588
PNG
(CHEMBL257594)
Show SMILES Cc1ccc2c(NNC(=O)c3ccccc3O)c3ccccc3nc2c1C
Show InChI InChI=1S/C22H19N3O2/c1-13-11-12-17-20(14(13)2)23-18-9-5-3-7-15(18)21(17)24-25-22(27)16-8-4-6-10-19(16)26/h3-12,26H,1-2H3,(H,23,24)(H,25,27)
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n/an/a 0.130n/an/an/an/an/an/a



University of Karachi

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum plasmepsin-2 by FRET assay


Bioorg Med Chem Lett 18: 3011-5 (2008)

More data for this
Ligand-Target Pair
Plasmepsin 2


(Plasmodium falciparum)
BDBM50323737
PNG
(CHEMBL1213687 | N-((2S)-1-((2S)-6-amino-1-(4-(6-me...)
Show SMILES CCCCNC(=O)C[C@H](O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)c1ccc(Oc2ccc(cc2)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCCCC(C)Nc2cc(OC)cc3cccnc23)cc1)[C@@H](C)CC
Show InChI InChI=1S/C59H87N9O9/c1-10-12-29-61-52(70)36-51(69)48(32-37(3)4)66-59(75)53(39(7)11-2)68-56(72)42-22-26-45(27-23-42)77-44-24-20-41(21-25-44)55(71)67-50(33-38(5)6)58(74)65-47(19-13-14-28-60)57(73)63-31-15-17-40(8)64-49-35-46(76-9)34-43-18-16-30-62-54(43)49/h16,18,20-27,30,34-35,37-40,47-48,50-51,53,64,69H,10-15,17,19,28-29,31-33,36,60H2,1-9H3,(H,61,70)(H,63,73)(H,65,74)(H,66,75)(H,67,71)(H,68,72)/t39-,40?,47-,48-,50-,51-,53-/m0/s1
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n/an/a 0.590n/an/an/an/an/an/a



National Institute of Pharmaceutical Education and Research

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum plasmepsin 2


Eur J Med Chem 45: 3245-64 (2010)

More data for this
Ligand-Target Pair
Plasmepsin 2


(Plasmodium falciparum)
BDBM50366912
PNG
(CHEMBL1790774)
Show SMILES CCCCNC(=O)C[C@H](O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)c1ccc(Oc2ccc(cc2)C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)NCCCC(C)Nc2cc(OC)cc3cccnc23)cc1)[C@H](C)CC
Show InChI InChI=1S/C59H87N9O9/c1-10-12-29-61-52(70)36-51(69)48(32-37(3)4)66-59(75)53(39(7)11-2)68-56(72)42-22-26-45(27-23-42)77-44-24-20-41(21-25-44)55(71)67-50(33-38(5)6)58(74)65-47(19-13-14-28-60)57(73)63-31-15-17-40(8)64-49-35-46(76-9)34-43-18-16-30-62-54(43)49/h16,18,20-27,30,34-35,37-40,47-48,50-51,53,64,69H,10-15,17,19,28-29,31-33,36,60H2,1-9H3,(H,61,70)(H,63,73)(H,65,74)(H,66,75)(H,67,71)(H,68,72)/t39-,40?,47-,48+,50-,51+,53+/m1/s1
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n/an/a 0.590n/an/an/an/an/an/a



University of Milan

Curated by ChEMBL


Assay Description
In vitro concentration required for inhibition of Plasmodium falciparum plasmepsin-2


Bioorg Med Chem Lett 14: 2931-4 (2004)

More data for this
Ligand-Target Pair
Plasmepsin 2


(Plasmodium falciparum)
BDBM912
PNG
((3S,4S)-3-hydroxy-4-[(2S)-2-[(3S,4S)-3-hydroxy-6-m...)
Show SMILES CC(C)C[C@H](NC(=O)[C@H](C)NC(=O)C[C@H](O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)CC(C)C)C(C)C)C(C)C)[C@@H](O)CC(O)=O
Show InChI InChI=1S/C34H63N5O9/c1-17(2)12-23(37-33(47)31(21(9)10)39-34(48)30(20(7)8)38-27(42)14-19(5)6)25(40)15-28(43)35-22(11)32(46)36-24(13-18(3)4)26(41)16-29(44)45/h17-26,30-31,40-41H,12-16H2,1-11H3,(H,35,43)(H,36,46)(H,37,47)(H,38,42)(H,39,48)(H,44,45)/t22-,23-,24-,25-,26-,30-,31-/m0/s1
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n/an/a 0.680n/an/an/an/an/an/a



University of Karachi

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum plasmepsin-2 by FRET assay


Bioorg Med Chem Lett 18: 3011-5 (2008)

More data for this
Ligand-Target Pair
Plasmepsin 2


(Plasmodium falciparum)
BDBM50366909
PNG
(CHEMBL1790773)
Show SMILES CCCCNC(=O)C[C@H](O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)c1ccc2cc(ccc2c1)C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)NCCCC(C)Nc1cc(OC)cc2cccnc12)[C@H](C)CC
Show InChI InChI=1S/C57H85N9O8/c1-10-12-25-59-50(68)34-49(67)46(28-35(3)4)64-57(73)51(37(7)11-2)66-54(70)43-23-21-39-30-42(22-20-40(39)31-43)53(69)65-48(29-36(5)6)56(72)63-45(19-13-14-24-58)55(71)61-27-15-17-38(8)62-47-33-44(74-9)32-41-18-16-26-60-52(41)47/h16,18,20-23,26,30-33,35-38,45-46,48-49,51,62,67H,10-15,17,19,24-25,27-29,34,58H2,1-9H3,(H,59,68)(H,61,71)(H,63,72)(H,64,73)(H,65,69)(H,66,70)/t37-,38?,45-,46+,48-,49+,51+/m1/s1
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n/an/a 1.51n/an/an/an/an/an/a



University of Milan

Curated by ChEMBL


Assay Description
In vitro concentration required for inhibition of Plasmodium falciparum plasmepsin-2


Bioorg Med Chem Lett 14: 2931-4 (2004)

More data for this
Ligand-Target Pair
Plasmepsin 2


(Plasmodium falciparum)
BDBM234547
PNG
(US9353089, 304)
Show SMILES COc1ccc(cc1)C1(NC(=N)N(Cc2ccccc2C(F)(F)F)C1=O)c1ccc(OC)cc1
Show InChI InChI=1S/C25H22F3N3O3/c1-33-19-11-7-17(8-12-19)24(18-9-13-20(34-2)14-10-18)22(32)31(23(29)30-24)15-16-5-3-4-6-21(16)25(26,27)28/h3-14H,15H2,1-2H3,(H2,29,30)
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n/an/a 1.88n/an/an/an/an/an/a



Saint Louis University; Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences

US Patent


Assay Description
Plasmepsin-2 (PM-2; Plm II) and Plasmepsin (PM-4; Plm IV) expression and purification was performed following the published protocols (Istvan E S and...


Citation and Details
More data for this
Ligand-Target Pair
Plasmepsin 2


(Plasmodium falciparum)
BDBM234565
PNG
(US9353089, 311)
Show SMILES COc1ccc(cc1)C1(NC(=N)N(C2CCN(CC2)C(=O)c2ccccc2)C1=O)c1ccc(OC)cc1
Show InChI InChI=1S/C29H30N4O4/c1-36-24-12-8-21(9-13-24)29(22-10-14-25(37-2)15-11-22)27(35)33(28(30)31-29)23-16-18-32(19-17-23)26(34)20-6-4-3-5-7-20/h3-15,23H,16-19H2,1-2H3,(H2,30,31)
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n/an/a 2n/an/an/an/an/an/a



Saint Louis University; Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences

US Patent


Assay Description
Plasmepsin-2 (PM-2; Plm II) and Plasmepsin (PM-4; Plm IV) expression and purification was performed following the published protocols (Istvan E S and...


Citation and Details
More data for this
Ligand-Target Pair
Plasmepsin 2


(Plasmodium falciparum)
BDBM234542
PNG
(US9353089, 276)
Show SMILES COc1ccc(cc1)C1(NC(=N)N(CC23CC4CC(CC(C4)C2)C3)C1=O)c1ccc(OC)cc1
Show InChI InChI=1S/C28H33N3O3/c1-33-23-7-3-21(4-8-23)28(22-5-9-24(34-2)10-6-22)25(32)31(26(29)30-28)17-27-14-18-11-19(15-27)13-20(12-18)16-27/h3-10,18-20H,11-17H2,1-2H3,(H2,29,30)
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n/an/a 2n/an/an/an/an/an/a



Saint Louis University; Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences

US Patent


Assay Description
Plasmepsin-2 (PM-2; Plm II) and Plasmepsin (PM-4; Plm IV) expression and purification was performed following the published protocols (Istvan E S and...


Citation and Details
More data for this
Ligand-Target Pair
Plasmepsin 2


(Plasmodium falciparum)
BDBM234527
PNG
(US9353089, 206)
Show SMILES COc1ccc(cc1)C1(NC(=N)N(C2CCN(CC2)C(=O)OC(C)(C)C)C1=O)c1ccc(OC)cc1
Show InChI InChI=1S/C27H34N4O5/c1-26(2,3)36-25(33)30-16-14-20(15-17-30)31-23(32)27(29-24(31)28,18-6-10-21(34-4)11-7-18)19-8-12-22(35-5)13-9-19/h6-13,20H,14-17H2,1-5H3,(H2,28,29)
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n/an/a 2n/an/an/an/an/an/a



Saint Louis University; Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences

US Patent


Assay Description
Plasmepsin-2 (PM-2; Plm II) and Plasmepsin (PM-4; Plm IV) expression and purification was performed following the published protocols (Istvan E S and...


Citation and Details
More data for this
Ligand-Target Pair
Plasmepsin 2


(Plasmodium falciparum)
BDBM234537
PNG
(US9353089, 238)
Show SMILES N=C1NC(C(=O)N1C1CCCCC1)(c1ccccc1)c1cccc(Oc2ccccc2)c1
Show InChI InChI=1S/C27H27N3O2/c28-26-29-27(20-11-4-1-5-12-20,25(31)30(26)22-14-6-2-7-15-22)21-13-10-18-24(19-21)32-23-16-8-3-9-17-23/h1,3-5,8-13,16-19,22H,2,6-7,14-15H2,(H2,28,29)
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n/an/a 2.20n/an/an/an/an/an/a



Saint Louis University; Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences

US Patent


Assay Description
Plasmepsin-2 (PM-2; Plm II) and Plasmepsin (PM-4; Plm IV) expression and purification was performed following the published protocols (Istvan E S and...


Citation and Details
More data for this
Ligand-Target Pair
Plasmepsin 2


(Plasmodium falciparum)
BDBM234534
PNG
(US9353089, 220)
Show SMILES COc1ccc(cc1)C1(NC(=N)N(C2CCCCCC2)C1=O)c1ccc(OC)cc1
Show InChI InChI=1S/C24H29N3O3/c1-29-20-13-9-17(10-14-20)24(18-11-15-21(30-2)16-12-18)22(28)27(23(25)26-24)19-7-5-3-4-6-8-19/h9-16,19H,3-8H2,1-2H3,(H2,25,26)
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n/an/a 2.37n/an/an/an/an/an/a



Saint Louis University; Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences

US Patent


Assay Description
Plasmepsin-2 (PM-2; Plm II) and Plasmepsin (PM-4; Plm IV) expression and purification was performed following the published protocols (Istvan E S and...


Citation and Details
More data for this
Ligand-Target Pair
Plasmepsin 2


(Plasmodium falciparum)
BDBM234535
PNG
(US9353089, 221)
Show SMILES COc1ccc(cc1)C1(NC(=N)N(CC2CCCCC2)C1=O)c1ccc(OC)cc1
Show InChI InChI=1S/C24H29N3O3/c1-29-20-12-8-18(9-13-20)24(19-10-14-21(30-2)15-11-19)22(28)27(23(25)26-24)16-17-6-4-3-5-7-17/h8-15,17H,3-7,16H2,1-2H3,(H2,25,26)
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n/an/a 2.39n/an/an/an/an/an/a



Saint Louis University; Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences

US Patent


Assay Description
Plasmepsin-2 (PM-2; Plm II) and Plasmepsin (PM-4; Plm IV) expression and purification was performed following the published protocols (Istvan E S and...


Citation and Details
More data for this
Ligand-Target Pair
Plasmepsin 2


(Plasmodium falciparum)
BDBM234544
PNG
(US9353089, 278)
Show SMILES COc1ccc(cc1)C1(NC(=N)N(Cc2c(C)cccc2C)C1=O)c1ccc(OC)cc1
Show InChI InChI=1S/C26H27N3O3/c1-17-6-5-7-18(2)23(17)16-29-24(30)26(28-25(29)27,19-8-12-21(31-3)13-9-19)20-10-14-22(32-4)15-11-20/h5-15H,16H2,1-4H3,(H2,27,28)
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n/an/a 2.76n/an/an/an/an/an/a



Saint Louis University; Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences

US Patent


Assay Description
Plasmepsin-2 (PM-2; Plm II) and Plasmepsin (PM-4; Plm IV) expression and purification was performed following the published protocols (Istvan E S and...


Citation and Details
More data for this
Ligand-Target Pair
Plasmepsin 2


(Plasmodium falciparum)
BDBM234527
PNG
(US9353089, 206)
Show SMILES COc1ccc(cc1)C1(NC(=N)N(C2CCN(CC2)C(=O)OC(C)(C)C)C1=O)c1ccc(OC)cc1
Show InChI InChI=1S/C27H34N4O5/c1-26(2,3)36-25(33)30-16-14-20(15-17-30)31-23(32)27(29-24(31)28,18-6-10-21(34-4)11-7-18)19-8-12-22(35-5)13-9-19/h6-13,20H,14-17H2,1-5H3,(H2,28,29)
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n/an/a 2.76n/an/an/an/an/an/a



Saint Louis University; Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences

US Patent


Assay Description
Plasmepsin-2 (PM-2; Plm II) and Plasmepsin (PM-4; Plm IV) expression and purification was performed following the published protocols (Istvan E S and...


Citation and Details
More data for this
Ligand-Target Pair
Plasmepsin 2


(Plasmodium falciparum)
BDBM234536
PNG
(US9353089, 228)
Show SMILES N=C1NC(C(=O)N1C1CCCCC1)(c1ccccc1)c1cccc(OCc2ccccc2)c1
Show InChI InChI=1S/C28H29N3O2/c29-27-30-28(22-13-6-2-7-14-22,26(32)31(27)24-16-8-3-9-17-24)23-15-10-18-25(19-23)33-20-21-11-4-1-5-12-21/h1-2,4-7,10-15,18-19,24H,3,8-9,16-17,20H2,(H2,29,30)
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n/an/a 2.89n/an/an/an/an/an/a



Saint Louis University; Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences

US Patent


Assay Description
Plasmepsin-2 (PM-2; Plm II) and Plasmepsin (PM-4; Plm IV) expression and purification was performed following the published protocols (Istvan E S and...


Citation and Details
More data for this
Ligand-Target Pair
Plasmepsin 2


(Plasmodium falciparum)
BDBM234546
PNG
(US9353089, 303)
Show SMILES COc1ccc(cc1)C1(NC(=N)N(Cc2ccccc2C)C1=O)c1ccc(OC)cc1
Show InChI InChI=1S/C25H25N3O3/c1-17-6-4-5-7-18(17)16-28-23(29)25(27-24(28)26,19-8-12-21(30-2)13-9-19)20-10-14-22(31-3)15-11-20/h4-15H,16H2,1-3H3,(H2,26,27)
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n/an/a 3.10n/an/an/an/an/an/a



Saint Louis University; Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences

US Patent


Assay Description
Plasmepsin-2 (PM-2; Plm II) and Plasmepsin (PM-4; Plm IV) expression and purification was performed following the published protocols (Istvan E S and...


Citation and Details
More data for this
Ligand-Target Pair
Plasmepsin 2


(Plasmodium falciparum)
BDBM234497
PNG
(US9353089, 117)
Show SMILES COc1ccc(cc1)C1(NC(=N)N(C2CCCCC2)C1=O)c1ccc(OC)cc1
Show InChI InChI=1S/C23H27N3O3/c1-28-19-12-8-16(9-13-19)23(17-10-14-20(29-2)15-11-17)21(27)26(22(24)25-23)18-6-4-3-5-7-18/h8-15,18H,3-7H2,1-2H3,(H2,24,25)
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n/an/a 3.96n/an/an/an/an/an/a



Saint Louis University; Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences

US Patent


Assay Description
Plasmepsin-2 (PM-2; Plm II) and Plasmepsin (PM-4; Plm IV) expression and purification was performed following the published protocols (Istvan E S and...


Citation and Details
More data for this
Ligand-Target Pair
Plasmepsin 2


(Plasmodium falciparum)
BDBM234497
PNG
(US9353089, 117)
Show SMILES COc1ccc(cc1)C1(NC(=N)N(C2CCCCC2)C1=O)c1ccc(OC)cc1
Show InChI InChI=1S/C23H27N3O3/c1-28-19-12-8-16(9-13-19)23(17-10-14-20(29-2)15-11-17)21(27)26(22(24)25-23)18-6-4-3-5-7-18/h8-15,18H,3-7H2,1-2H3,(H2,24,25)
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n/an/a 4n/an/an/an/an/an/a



Saint Louis University; Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences

US Patent


Assay Description
Plasmepsin-2 (PM-2; Plm II) and Plasmepsin (PM-4; Plm IV) expression and purification was performed following the published protocols (Istvan E S and...


Citation and Details
More data for this
Ligand-Target Pair
Plasmepsin 2


(Plasmodium falciparum)
BDBM50377587
PNG
(CHEMBL404394)
Show SMILES Cc1cccc(c1)C(=O)NNc1c2ccccc2nc2c(C)c(C)ccc12
Show InChI InChI=1S/C23H21N3O/c1-14-7-6-8-17(13-14)23(27)26-25-22-18-9-4-5-10-20(18)24-21-16(3)15(2)11-12-19(21)22/h4-13H,1-3H3,(H,24,25)(H,26,27)
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n/an/a 4n/an/an/an/an/an/a



University of Karachi

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum plasmepsin-2 by FRET assay


Bioorg Med Chem Lett 18: 3011-5 (2008)

More data for this
Ligand-Target Pair
Plasmepsin 2


(Plasmodium falciparum)
BDBM234543
PNG
(US9353089, 277)
Show SMILES COc1ccc(cc1)C1(NC(=N)N(Cc2cccc(C)c2C)C1=O)c1ccc(OC)cc1
Show InChI InChI=1S/C26H27N3O3/c1-17-6-5-7-19(18(17)2)16-29-24(30)26(28-25(29)27,20-8-12-22(31-3)13-9-20)21-10-14-23(32-4)15-11-21/h5-15H,16H2,1-4H3,(H2,27,28)
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n/an/a 4.39n/an/an/an/an/an/a



Saint Louis University; Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences

US Patent


Assay Description
Plasmepsin-2 (PM-2; Plm II) and Plasmepsin (PM-4; Plm IV) expression and purification was performed following the published protocols (Istvan E S and...


Citation and Details
More data for this
Ligand-Target Pair
Plasmepsin 2


(Plasmodium falciparum)
BDBM234539
PNG
(US9353089, 252)
Show SMILES COc1ccc(cc1)C1(NC(=N)N(CC(C)(C)C)C1=O)c1ccc(OC)cc1
Show InChI InChI=1S/C22H27N3O3/c1-21(2,3)14-25-19(26)22(24-20(25)23,15-6-10-17(27-4)11-7-15)16-8-12-18(28-5)13-9-16/h6-13H,14H2,1-5H3,(H2,23,24)
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n/an/a 5.28n/an/an/an/an/an/a



Saint Louis University; Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences

US Patent


Assay Description
Plasmepsin-2 (PM-2; Plm II) and Plasmepsin (PM-4; Plm IV) expression and purification was performed following the published protocols (Istvan E S and...


Citation and Details
More data for this
Ligand-Target Pair
Plasmepsin 2


(Plasmodium falciparum)
BDBM234529
PNG
(US9353089, 210)
Show SMILES COc1ccc(cc1)C1(NC(=N)N(C2CCCCC2)C1=O)c1cccc(c1)-c1ccccn1
Show InChI InChI=1S/C27H28N4O2/c1-33-23-15-13-20(14-16-23)27(21-9-7-8-19(18-21)24-12-5-6-17-29-24)25(32)31(26(28)30-27)22-10-3-2-4-11-22/h5-9,12-18,22H,2-4,10-11H2,1H3,(H2,28,30)
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n/an/a 5.47n/an/an/an/an/an/a



Saint Louis University; Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences

US Patent


Assay Description
Plasmepsin-2 (PM-2; Plm II) and Plasmepsin (PM-4; Plm IV) expression and purification was performed following the published protocols (Istvan E S and...


Citation and Details
More data for this
Ligand-Target Pair
Plasmepsin 2


(Plasmodium falciparum)
BDBM234564
PNG
(US9353089, 310)
Show SMILES COc1ccc(cc1)C1(NC(=N)N(C2CCN(CC2)C(C)=O)C1=O)c1ccc(OC)cc1
Show InChI InChI=1S/C24H28N4O4/c1-16(29)27-14-12-19(13-15-27)28-22(30)24(26-23(28)25,17-4-8-20(31-2)9-5-17)18-6-10-21(32-3)11-7-18/h4-11,19H,12-15H2,1-3H3,(H2,25,26)
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n/an/a 5.84n/an/an/an/an/an/a



Saint Louis University; Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences

US Patent


Assay Description
Plasmepsin-2 (PM-2; Plm II) and Plasmepsin (PM-4; Plm IV) expression and purification was performed following the published protocols (Istvan E S and...


Citation and Details
More data for this
Ligand-Target Pair
Plasmepsin 2


(Plasmodium falciparum)
BDBM234508
PNG
(US9353089, 155)
Show SMILES Clc1ccc(cc1)C1(NC(=N)N(C2CCCCC2)C1=O)c1ccc(Cl)cc1
Show InChI InChI=1S/C21H21Cl2N3O/c22-16-10-6-14(7-11-16)21(15-8-12-17(23)13-9-15)19(27)26(20(24)25-21)18-4-2-1-3-5-18/h6-13,18H,1-5H2,(H2,24,25)
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n/an/a 6n/an/an/an/an/an/a



Saint Louis University; Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences

US Patent


Assay Description
Plasmepsin-2 (PM-2; Plm II) and Plasmepsin (PM-4; Plm IV) expression and purification was performed following the published protocols (Istvan E S and...


Citation and Details
More data for this
Ligand-Target Pair
Plasmepsin 2


(Plasmodium falciparum)
BDBM50195377
PNG
((4'-{[[1-(3-methyl-butyl)-piperidin-4-yl]-(4-penty...)
Show SMILES CCCCCc1ccc(cc1)C(=O)N(Cc1ccc(cc1)-c1ccc(CC(=O)OC)cc1)C1CCN(CCC(C)C)CC1
Show InChI InChI=1S/C38H50N2O3/c1-5-6-7-8-30-9-19-35(20-10-30)38(42)40(36-22-25-39(26-23-36)24-21-29(2)3)28-32-13-17-34(18-14-32)33-15-11-31(12-16-33)27-37(41)43-4/h9-20,29,36H,5-8,21-28H2,1-4H3
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n/an/a 6n/an/an/an/an/an/a



Actelion Pharmaceuticals Ltd

Curated by ChEMBL


Assay Description
Inhibition of PM2 by FRET assay


Bioorg Med Chem Lett 16: 6194-9 (2006)

More data for this
Ligand-Target Pair
Plasmepsin 2


(Plasmodium falciparum)
BDBM234520
PNG
(US9353089, 176)
Show SMILES COc1ccc(cc1)C1(NC(=N)N(C2CCOCC2)C1=O)c1ccc(OC)cc1
Show InChI InChI=1S/C22H25N3O4/c1-27-18-7-3-15(4-8-18)22(16-5-9-19(28-2)10-6-16)20(26)25(21(23)24-22)17-11-13-29-14-12-17/h3-10,17H,11-14H2,1-2H3,(H2,23,24)
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n/an/a 6.81n/an/an/an/an/an/a



Saint Louis University; Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences

US Patent


Assay Description
Plasmepsin-2 (PM-2; Plm II) and Plasmepsin (PM-4; Plm IV) expression and purification was performed following the published protocols (Istvan E S and...


Citation and Details
More data for this
Ligand-Target Pair
Plasmepsin 2


(Plasmodium falciparum)
BDBM234510
PNG
(US9353089, 157)
Show SMILES CCOc1ccc(cc1)C1(NC(=N)N(C2CCCCC2)C1=O)c1ccc(OCC)cc1
Show InChI InChI=1S/C25H31N3O3/c1-3-30-21-14-10-18(11-15-21)25(19-12-16-22(17-13-19)31-4-2)23(29)28(24(26)27-25)20-8-6-5-7-9-20/h10-17,20H,3-9H2,1-2H3,(H2,26,27)
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n/an/a 6.87n/an/an/an/an/an/a



Saint Louis University; Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences

US Patent


Assay Description
Plasmepsin-2 (PM-2; Plm II) and Plasmepsin (PM-4; Plm IV) expression and purification was performed following the published protocols (Istvan E S and...


Citation and Details
More data for this
Ligand-Target Pair
Plasmepsin 2


(Plasmodium falciparum)
BDBM234517
PNG
(US9353089, 171)
Show SMILES COc1ccc(cc1)C1(NC(=N)N(C2CCCCC2)C1=O)c1cccc(c1)-c1cccnc1
Show InChI InChI=1S/C27H28N4O2/c1-33-24-14-12-21(13-15-24)27(22-9-5-7-19(17-22)20-8-6-16-29-18-20)25(32)31(26(28)30-27)23-10-3-2-4-11-23/h5-9,12-18,23H,2-4,10-11H2,1H3,(H2,28,30)
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n/an/a 6.97n/an/an/an/an/an/a



Saint Louis University; Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences

US Patent


Assay Description
Plasmepsin-2 (PM-2; Plm II) and Plasmepsin (PM-4; Plm IV) expression and purification was performed following the published protocols (Istvan E S and...


Citation and Details
More data for this
Ligand-Target Pair
Plasmepsin 2


(Plasmodium falciparum)
BDBM234520
PNG
(US9353089, 176)
Show SMILES COc1ccc(cc1)C1(NC(=N)N(C2CCOCC2)C1=O)c1ccc(OC)cc1
Show InChI InChI=1S/C22H25N3O4/c1-27-18-7-3-15(4-8-18)22(16-5-9-19(28-2)10-6-16)20(26)25(21(23)24-22)17-11-13-29-14-12-17/h3-10,17H,11-14H2,1-2H3,(H2,23,24)
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n/an/a 7n/an/an/an/an/an/a



Saint Louis University; Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences

US Patent


Assay Description
Plasmepsin-2 (PM-2; Plm II) and Plasmepsin (PM-4; Plm IV) expression and purification was performed following the published protocols (Istvan E S and...


Citation and Details
More data for this
Ligand-Target Pair
Plasmepsin 2


(Plasmodium falciparum)
BDBM234517
PNG
(US9353089, 171)
Show SMILES COc1ccc(cc1)C1(NC(=N)N(C2CCCCC2)C1=O)c1cccc(c1)-c1cccnc1
Show InChI InChI=1S/C27H28N4O2/c1-33-24-14-12-21(13-15-24)27(22-9-5-7-19(17-22)20-8-6-16-29-18-20)25(32)31(26(28)30-27)23-10-3-2-4-11-23/h5-9,12-18,23H,2-4,10-11H2,1H3,(H2,28,30)
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n/an/a 7n/an/an/an/an/an/a



Saint Louis University; Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences

US Patent


Assay Description
Plasmepsin-2 (PM-2; Plm II) and Plasmepsin (PM-4; Plm IV) expression and purification was performed following the published protocols (Istvan E S and...


Citation and Details
More data for this
Ligand-Target Pair
Plasmepsin 2


(Plasmodium falciparum)
BDBM234513
PNG
(US9353089, 162)
Show SMILES COc1ccc(cc1)C1(NC(=N)N(Cc2ccccc2)C1=O)c1ccc(OC)cc1
Show InChI InChI=1S/C24H23N3O3/c1-29-20-12-8-18(9-13-20)24(19-10-14-21(30-2)15-11-19)22(28)27(23(25)26-24)16-17-6-4-3-5-7-17/h3-15H,16H2,1-2H3,(H2,25,26)
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n/an/a 7.30n/an/an/an/an/an/a



Saint Louis University; Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences

US Patent


Assay Description
Plasmepsin-2 (PM-2; Plm II) and Plasmepsin (PM-4; Plm IV) expression and purification was performed following the published protocols (Istvan E S and...


Citation and Details
More data for this
Ligand-Target Pair
Plasmepsin 2


(Plasmodium falciparum)
BDBM234567
PNG
(US9353089, 305)
Show SMILES COc1ccc(cc1)C1(NC(=N)N(Cc2ccccc2C#N)C1=O)c1ccc(OC)cc1
Show InChI InChI=1S/C25H22N4O3/c1-31-21-11-7-19(8-12-21)25(20-9-13-22(32-2)14-10-20)23(30)29(24(27)28-25)16-18-6-4-3-5-17(18)15-26/h3-14H,16H2,1-2H3,(H2,27,28)
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n/an/a 9.30n/an/an/an/an/an/a



Saint Louis University; Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences

US Patent


Assay Description
Plasmepsin-2 (PM-2; Plm II) and Plasmepsin (PM-4; Plm IV) expression and purification was performed following the published protocols (Istvan E S and...


Citation and Details
More data for this
Ligand-Target Pair
Plasmepsin 2


(Plasmodium falciparum)
BDBM50366908
PNG
(CHEMBL1790772)
Show SMILES CCCCNC(=O)C[C@H](O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)c1ccc2cc(ccc2c1)C(=O)OCCCC(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)NCCCC(C)Nc1cc(OC)cc2cccnc12)[C@H](C)CC
Show InChI InChI=1S/C61H91N9O10/c1-10-12-27-63-54(73)37-52(71)49(31-38(3)4)69-60(77)55(40(7)11-2)70-57(74)45-24-22-43-34-46(25-23-42(43)33-45)61(78)80-30-17-21-53(72)67-51(32-39(5)6)59(76)68-48(20-13-14-26-62)58(75)65-29-15-18-41(8)66-50-36-47(79-9)35-44-19-16-28-64-56(44)50/h16,19,22-25,28,33-36,38-41,48-49,51-52,55,66,71H,10-15,17-18,20-21,26-27,29-32,37,62H2,1-9H3,(H,63,73)(H,65,75)(H,67,72)(H,68,76)(H,69,77)(H,70,74)/t40-,41?,48-,49+,51-,52+,55+/m1/s1
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n/an/a 9.60n/an/an/an/an/an/a



University of Milan

Curated by ChEMBL


Assay Description
In vitro concentration required for inhibition of Plasmodium falciparum plasmepsin-2


Bioorg Med Chem Lett 14: 2931-4 (2004)

More data for this
Ligand-Target Pair
Plasmepsin 2


(Plasmodium falciparum)
BDBM234533
PNG
(US9353089, 219)
Show SMILES COc1ccc(cc1)C1(NC(=N)N(Cc2cccnc2)C1=O)c1ccc(OC)cc1
Show InChI InChI=1S/C23H22N4O3/c1-29-19-9-5-17(6-10-19)23(18-7-11-20(30-2)12-8-18)21(28)27(22(24)26-23)15-16-4-3-13-25-14-16/h3-14H,15H2,1-2H3,(H2,24,26)
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n/an/a 9.62n/an/an/an/an/an/a



Saint Louis University; Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences

US Patent


Assay Description
Plasmepsin-2 (PM-2; Plm II) and Plasmepsin (PM-4; Plm IV) expression and purification was performed following the published protocols (Istvan E S and...


Citation and Details
More data for this
Ligand-Target Pair
Plasmepsin 2


(Plasmodium falciparum)
BDBM234518
PNG
(US9353089, 172)
Show SMILES COc1ccc(cc1)C1(NC(=N)N(C2CCCCC2)C1=O)c1cccc(c1)-c1ccncc1
Show InChI InChI=1S/C27H28N4O2/c1-33-24-12-10-21(11-13-24)27(22-7-5-6-20(18-22)19-14-16-29-17-15-19)25(32)31(26(28)30-27)23-8-3-2-4-9-23/h5-7,10-18,23H,2-4,8-9H2,1H3,(H2,28,30)
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n/an/a 9.64n/an/an/an/an/an/a



Saint Louis University; Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences

US Patent


Assay Description
Plasmepsin-2 (PM-2; Plm II) and Plasmepsin (PM-4; Plm IV) expression and purification was performed following the published protocols (Istvan E S and...


Citation and Details
More data for this
Ligand-Target Pair
Plasmepsin 2


(Plasmodium falciparum)
BDBM234507
PNG
(US9353089, 154)
Show SMILES Brc1ccc(cc1)C1(NC(=N)N(C2CCCCC2)C1=O)c1ccc(Br)cc1
Show InChI InChI=1S/C21H21Br2N3O/c22-16-10-6-14(7-11-16)21(15-8-12-17(23)13-9-15)19(27)26(20(24)25-21)18-4-2-1-3-5-18/h6-13,18H,1-5H2,(H2,24,25)
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n/an/a 9.90n/an/an/an/an/an/a



Saint Louis University; Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences

US Patent


Assay Description
Plasmepsin-2 (PM-2; Plm II) and Plasmepsin (PM-4; Plm IV) expression and purification was performed following the published protocols (Istvan E S and...


Citation and Details
More data for this
Ligand-Target Pair
Plasmepsin 2


(Plasmodium falciparum)
BDBM234504
PNG
(US9353089, 141)
Show SMILES COc1ccc(cc1)C1(NC(=N)N(C2CCCCC2)C1=O)c1ccccc1
Show InChI InChI=1S/C22H25N3O2/c1-27-19-14-12-17(13-15-19)22(16-8-4-2-5-9-16)20(26)25(21(23)24-22)18-10-6-3-7-11-18/h2,4-5,8-9,12-15,18H,3,6-7,10-11H2,1H3,(H2,23,24)
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n/an/a 10.6n/an/an/an/an/an/a



Saint Louis University; Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences

US Patent


Assay Description
Plasmepsin-2 (PM-2; Plm II) and Plasmepsin (PM-4; Plm IV) expression and purification was performed following the published protocols (Istvan E S and...


Citation and Details
More data for this
Ligand-Target Pair
Plasmepsin 2


(Plasmodium falciparum)
BDBM234549
PNG
(US9353089, 313)
Show SMILES COc1ccc(cc1)C1(NC(=N)N(CC2CCN(CC2)C(=O)OC(C)(C)C)C1=O)c1ccc(OC)cc1
Show InChI InChI=1S/C28H36N4O5/c1-27(2,3)37-26(34)31-16-14-19(15-17-31)18-32-24(33)28(30-25(32)29,20-6-10-22(35-4)11-7-20)21-8-12-23(36-5)13-9-21/h6-13,19H,14-18H2,1-5H3,(H2,29,30)
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n/an/a 11n/an/an/an/an/an/a



Saint Louis University; Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences

US Patent


Assay Description
Plasmepsin-2 (PM-2; Plm II) and Plasmepsin (PM-4; Plm IV) expression and purification was performed following the published protocols (Istvan E S and...


Citation and Details
More data for this
Ligand-Target Pair
Plasmepsin 2


(Plasmodium falciparum)
BDBM234551
PNG
(US9353089, 324)
Show SMILES COc1cccc(c1)-c1cccc(c1)C1(NC(=N)N(C2CCOCC2)C1=O)c1ccccc1
Show InChI InChI=1S/C27H27N3O3/c1-32-24-12-6-8-20(18-24)19-7-5-11-22(17-19)27(21-9-3-2-4-10-21)25(31)30(26(28)29-27)23-13-15-33-16-14-23/h2-12,17-18,23H,13-16H2,1H3,(H2,28,29)
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n/an/a 11.3n/an/an/an/an/an/a



Saint Louis University; Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences

US Patent


Assay Description
Plasmepsin-2 (PM-2; Plm II) and Plasmepsin (PM-4; Plm IV) expression and purification was performed following the published protocols (Istvan E S and...


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More data for this
Ligand-Target Pair
Plasmepsin 2


(Plasmodium falciparum)
BDBM234551
PNG
(US9353089, 324)
Show SMILES COc1cccc(c1)-c1cccc(c1)C1(NC(=N)N(C2CCOCC2)C1=O)c1ccccc1
Show InChI InChI=1S/C27H27N3O3/c1-32-24-12-6-8-20(18-24)19-7-5-11-22(17-19)27(21-9-3-2-4-10-21)25(31)30(26(28)29-27)23-13-15-33-16-14-23/h2-12,17-18,23H,13-16H2,1H3,(H2,28,29)
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UniChem
US Patent
n/an/a 11.3n/an/an/an/an/an/a



Saint Louis University; Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences

US Patent


Assay Description
Plasmepsin-2 (PM-2; Plm II) and Plasmepsin (PM-4; Plm IV) expression and purification was performed following the published protocols (Istvan E S and...


Citation and Details
More data for this
Ligand-Target Pair
Plasmepsin 2


(Plasmodium falciparum)
BDBM234540
PNG
(US9353089, 274)
Show SMILES COc1ccc(cc1)C1(NC(=N)N(CC2CCCO2)C1=O)c1ccc(OC)cc1
Show InChI InChI=1S/C22H25N3O4/c1-27-17-9-5-15(6-10-17)22(16-7-11-18(28-2)12-8-16)20(26)25(21(23)24-22)14-19-4-3-13-29-19/h5-12,19H,3-4,13-14H2,1-2H3,(H2,23,24)
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US Patent
n/an/a 11.4n/an/an/an/an/an/a



Saint Louis University; Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences

US Patent


Assay Description
Plasmepsin-2 (PM-2; Plm II) and Plasmepsin (PM-4; Plm IV) expression and purification was performed following the published protocols (Istvan E S and...


Citation and Details
More data for this
Ligand-Target Pair
Plasmepsin 2


(Plasmodium falciparum)
BDBM234521
PNG
(US9353089, 177)
Show SMILES COc1ccc(cc1)C1(NC(=N)N(C2CCCCC2)C1=O)c1cccc(c1)-c1ccccc1
Show InChI InChI=1S/C28H29N3O2/c1-33-25-17-15-22(16-18-25)28(23-12-8-11-21(19-23)20-9-4-2-5-10-20)26(32)31(27(29)30-28)24-13-6-3-7-14-24/h2,4-5,8-12,15-19,24H,3,6-7,13-14H2,1H3,(H2,29,30)
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US Patent
n/an/a 11.7n/an/an/an/an/an/a



Saint Louis University; Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences

US Patent


Assay Description
Plasmepsin-2 (PM-2; Plm II) and Plasmepsin (PM-4; Plm IV) expression and purification was performed following the published protocols (Istvan E S and...


Citation and Details
More data for this
Ligand-Target Pair
Plasmepsin 2


(Plasmodium falciparum)
BDBM234532
PNG
(US9353089, 214)
Show SMILES COc1cccc(c1)C1(NC(=N)N(C2CCCCC2)C1=O)c1cccc(c1)-c1cccnc1
Show InChI InChI=1S/C27H28N4O2/c1-33-24-14-6-11-22(17-24)27(21-10-5-8-19(16-21)20-9-7-15-29-18-20)25(32)31(26(28)30-27)23-12-3-2-4-13-23/h5-11,14-18,23H,2-4,12-13H2,1H3,(H2,28,30)
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n/an/a 12n/an/an/an/an/an/a



Saint Louis University; Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences

US Patent


Assay Description
Plasmepsin-2 (PM-2; Plm II) and Plasmepsin (PM-4; Plm IV) expression and purification was performed following the published protocols (Istvan E S and...


Citation and Details
More data for this
Ligand-Target Pair
Plasmepsin 2


(Plasmodium falciparum)
BDBM234576
PNG
(US9353089, Table 8, Compound 1)
Show SMILES CCC(CN1C(=N)NC(C1=O)(c1ccccc1)c1ccccc1)c1ccccc1
Show InChI InChI=1S/C25H25N3O/c1-2-19(20-12-6-3-7-13-20)18-28-23(29)25(27-24(28)26,21-14-8-4-9-15-21)22-16-10-5-11-17-22/h3-17,19H,2,18H2,1H3,(H2,26,27)
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US Patent
n/an/a 12n/an/an/an/an/an/a



Saint Louis University; Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences

US Patent


Assay Description
Plasmepsin-2 (PM-2; Plm II) and Plasmepsin (PM-4; Plm IV) expression and purification was performed following the published protocols (Istvan E S and...


Citation and Details
More data for this
Ligand-Target Pair
Plasmepsin 2


(Plasmodium falciparum)
BDBM50446323
PNG
(CHEMBL588662)
Show SMILES CCC(CN1C(=N)NC(C1=O)(c1ccccc1)c1ccccc1)c1ccccc1
Show InChI InChI=1S/C25H25N3O/c1-2-19(20-12-6-3-7-13-20)18-28-23(29)25(27-24(28)26,21-14-8-4-9-15-21)22-16-10-5-11-17-22/h3-17,19H,2,18H2,1H3,(H2,26,27)
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n/an/a 12n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of Plasmodium falciparum plasmepsin-2 after 60 mins by fluorescence assay


Citation and Details
More data for this
Ligand-Target Pair
Plasmepsin 2


(Plasmodium falciparum)
BDBM234531
PNG
(US9353089, 212)
Show SMILES N=C1NC(C(=O)N1C1CCCCC1)(c1ccccc1)c1cccc(c1)-c1ccccc1
Show InChI InChI=1S/C27H27N3O/c28-26-29-27(22-14-6-2-7-15-22,25(31)30(26)24-17-8-3-9-18-24)23-16-10-13-21(19-23)20-11-4-1-5-12-20/h1-2,4-7,10-16,19,24H,3,8-9,17-18H2,(H2,28,29)
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US Patent
n/an/a 12.3n/an/an/an/an/an/a



Saint Louis University; Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences

US Patent


Assay Description
Plasmepsin-2 (PM-2; Plm II) and Plasmepsin (PM-4; Plm IV) expression and purification was performed following the published protocols (Istvan E S and...


Citation and Details
More data for this
Ligand-Target Pair
Plasmepsin 2


(Plasmodium falciparum)
BDBM234503
PNG
(US9353089, 136)
Show SMILES N=C1NC(C(=O)N1C1CCCCC1)(c1ccccc1)c1cccc(c1)-c1cccnc1
Show InChI InChI=1S/C26H26N4O/c27-25-29-26(21-11-3-1-4-12-21,24(31)30(25)23-14-5-2-6-15-23)22-13-7-9-19(17-22)20-10-8-16-28-18-20/h1,3-4,7-13,16-18,23H,2,5-6,14-15H2,(H2,27,29)
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US Patent
n/an/a 13n/an/an/an/an/an/a



Saint Louis University; Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences

US Patent


Assay Description
Plasmepsin-2 (PM-2; Plm II) and Plasmepsin (PM-4; Plm IV) expression and purification was performed following the published protocols (Istvan E S and...


Citation and Details
More data for this
Ligand-Target Pair
Plasmepsin 2


(Plasmodium falciparum)
BDBM234503
PNG
(US9353089, 136)
Show SMILES N=C1NC(C(=O)N1C1CCCCC1)(c1ccccc1)c1cccc(c1)-c1cccnc1
Show InChI InChI=1S/C26H26N4O/c27-25-29-26(21-11-3-1-4-12-21,24(31)30(25)23-14-5-2-6-15-23)22-13-7-9-19(17-22)20-10-8-16-28-18-20/h1,3-4,7-13,16-18,23H,2,5-6,14-15H2,(H2,27,29)
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n/an/a 13n/an/an/an/an/an/a



Saint Louis University; Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences

US Patent


Assay Description
Plasmepsin-2 (PM-2; Plm II) and Plasmepsin (PM-4; Plm IV) expression and purification was performed following the published protocols (Istvan E S and...


Citation and Details
More data for this
Ligand-Target Pair
Plasmepsin 2


(Plasmodium falciparum)
BDBM234503
PNG
(US9353089, 136)
Show SMILES N=C1NC(C(=O)N1C1CCCCC1)(c1ccccc1)c1cccc(c1)-c1cccnc1
Show InChI InChI=1S/C26H26N4O/c27-25-29-26(21-11-3-1-4-12-21,24(31)30(25)23-14-5-2-6-15-23)22-13-7-9-19(17-22)20-10-8-16-28-18-20/h1,3-4,7-13,16-18,23H,2,5-6,14-15H2,(H2,27,29)
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n/an/a 13n/an/an/an/an/an/a



Saint Louis University; Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences

US Patent


Assay Description
Plasmepsin-2 (PM-2; Plm II) and Plasmepsin (PM-4; Plm IV) expression and purification was performed following the published protocols (Istvan E S and...


Citation and Details
More data for this
Ligand-Target Pair
Plasmepsin 2


(Plasmodium falciparum)
BDBM234509
PNG
(US9353089, 156)
Show SMILES Cc1ccc(cc1)C1(NC(=N)N(C2CCCCC2)C1=O)c1ccc(C)cc1
Show InChI InChI=1S/C23H27N3O/c1-16-8-12-18(13-9-16)23(19-14-10-17(2)11-15-19)21(27)26(22(24)25-23)20-6-4-3-5-7-20/h8-15,20H,3-7H2,1-2H3,(H2,24,25)
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US Patent
n/an/a 14n/an/an/an/an/an/a



Saint Louis University; Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences

US Patent


Assay Description
Plasmepsin-2 (PM-2; Plm II) and Plasmepsin (PM-4; Plm IV) expression and purification was performed following the published protocols (Istvan E S and...


Citation and Details
More data for this
Ligand-Target Pair
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