Compile Data Set for Download or QSAR
maximum 50k data
Found 154 of ki data for polymerid = 990
TargetPlasmepsin I(Plasmodium falciparum)
LinköPing University

Curated by ChEMBL
LigandPNGBDBM50169098(CHEMBL264770 | Pyridine-2-carboxylic acid {(S)-1-[...)
Affinity DataKi:  0.300nMAssay Description:Inhibitory concentration against the Plasmepsin I of Plasmodium falciparumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin I(Plasmodium falciparum)
LinköPing University

Curated by ChEMBL
LigandPNGBDBM50169100(CHEMBL191260 | Pyridine-2-carboxylic acid {(S)-1-[...)
Affinity DataKi:  0.300nMAssay Description:Inhibitory concentration against the Plasmepsin I of Plasmodium falciparumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin I(Plasmodium falciparum)
LinköPing University

Curated by ChEMBL
LigandPNGBDBM50169103(CHEMBL191130 | Pyridine-2-carboxylic acid {(S)-1-[...)
Affinity DataKi:  0.400nMAssay Description:Inhibitory concentration against the Plasmepsin I of Plasmodium falciparumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin I(Plasmodium falciparum)
LinköPing University

Curated by ChEMBL
LigandPNGBDBM50169104(CHEMBL371417 | Pyridine-2-carboxylic acid {(S)-1-[...)
Affinity DataKi:  0.400nMAssay Description:Inhibitory concentration against the Plasmepsin I of Plasmodium falciparumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin I(Plasmodium falciparum)
LinköPing University

Curated by ChEMBL
LigandPNGBDBM8007((2R,3R,4R,5R)-2,5-bis({[(2E)-3-(2H-1,3-benzodioxol...)
Affinity DataKi:  0.5nMAssay Description:Enzyme activities were assayed by monitoring the hydrolysis of substrate in the presence or absence of inhibitor compounds. The hydrolysis was record...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin I(Plasmodium falciparum)
LinköPing University

Curated by ChEMBL
LigandPNGBDBM7977((3S,4S)-5-[(4-bromophenyl)methoxy]-N-[(1S)-1-{[(1S...)
Affinity DataKi:  0.5nMAssay Description:Enzyme activities were assayed by monitoring the hydrolysis of substrate in the presence or absence of inhibitor compounds. The hydrolysis was record...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin I(Plasmodium falciparum)
LinköPing University

Curated by ChEMBL
LigandPNGBDBM7977((3S,4S)-5-[(4-bromophenyl)methoxy]-N-[(1S)-1-{[(1S...)
Affinity DataKi:  0.5nMAssay Description:Inhibitory concentration against the Plasmepsin I of Plasmodium falciparumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin I(Plasmodium falciparum)
LinköPing University

Curated by ChEMBL
LigandPNGBDBM50169106(CHEMBL363286 | Pyridine-2-carboxylic acid ((S)-1-{...)
Affinity DataKi:  0.700nMAssay Description:Inhibitory concentration against the Plasmepsin I of Plasmodium falciparumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin I(Plasmodium falciparum)
LinköPing University

Curated by ChEMBL
LigandPNGBDBM8005((2R,3R,4R,5R)-2,5-bis({[(2E)-3-(4-acetylphenyl)pro...)
Affinity DataKi:  0.800nMAssay Description:Enzyme activities were assayed by monitoring the hydrolysis of substrate in the presence or absence of inhibitor compounds. The hydrolysis was record...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin I(Plasmodium falciparum)
LinköPing University

Curated by ChEMBL
LigandPNGBDBM8005((2R,3R,4R,5R)-2,5-bis({[(2E)-3-(4-acetylphenyl)pro...)
Affinity DataKi:  0.800nMAssay Description:Inhibition of recombinant Plasmodium falciparum Plasmepsin 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin I(Plasmodium falciparum)
LinköPing University

Curated by ChEMBL
LigandPNGBDBM50169109(CHEMBL190290 | Pyridine-2-carboxylic acid ((S)-1-{...)
Affinity DataKi:  1nMAssay Description:Inhibitory concentration against the Plasmepsin I of Plasmodium falciparumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin I(Plasmodium falciparum)
LinköPing University

Curated by ChEMBL
LigandPNGBDBM50200018((3S,4S)-4-((2S,3S)-2-(4-(4-((S)-((S)-1-(1-(4-(6-me...)
Affinity DataKi:  1nMAssay Description:Inhibition of Plasmodium falciparum recombinant PLM1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin I(Plasmodium falciparum)
LinköPing University

Curated by ChEMBL
LigandPNGBDBM50169105(CHEMBL370086 | Pyridine-2-carboxylic acid {(S)-1-[...)
Affinity DataKi:  1nMAssay Description:Inhibitory concentration against the Plasmepsin I of Plasmodium falciparumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin I(Plasmodium falciparum)
LinköPing University

Curated by ChEMBL
LigandPNGBDBM8008((2R,3R,4R,5R)-3,4-dihydroxy-N,N'-bis[(1S,2R)-2-hyd...)
Affinity DataKi:  1.30nMAssay Description:Enzyme activities were assayed by monitoring the hydrolysis of substrate in the presence or absence of inhibitor compounds. The hydrolysis was record...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin I(Plasmodium falciparum)
LinköPing University

Curated by ChEMBL
LigandPNGBDBM8002((2R,3R,4R,5R)-3,4-dihydroxy-N,N'-bis[(1S,2R)-2-hyd...)
Affinity DataKi:  1.40nMAssay Description:Enzyme activities were assayed by monitoring the hydrolysis of substrate in the presence or absence of inhibitor compounds. The hydrolysis was record...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin I(Plasmodium falciparum)
LinköPing University

Curated by ChEMBL
LigandPNGBDBM50169110(CHEMBL364630 | Pyridine-2-carboxylic acid {(S)-1-[...)
Affinity DataKi:  1.90nMAssay Description:Inhibitory concentration against the Plasmepsin I of Plasmodium falciparumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin I(Plasmodium falciparum)
LinköPing University

Curated by ChEMBL
LigandPNGBDBM8099((2S)-N-[(2S,3S)-4-{[(1S)-1-carbamoyl-2-(4-phenylph...)
Affinity DataKi:  2nMAssay Description:Enzyme activities were assayed by monitoring the hydrolysis of substrate in the presence or absence of inhibitor compounds. The hydrolysis was record...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin I(Plasmodium falciparum)
LinköPing University

Curated by ChEMBL
LigandPNGBDBM50169112(CHEMBL371082 | N-[(1S,2S)-3-[(S)-1-((S)-1-Carbamoy...)
Affinity DataKi:  2.10nMAssay Description:Inhibitory concentration against the Plasmepsin I of Plasmodium falciparumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin I(Plasmodium falciparum)
LinköPing University

Curated by ChEMBL
LigandPNGBDBM8003((2R,3R,4R,5R)-2,5-bis({[(2E)-3-(4-fluorophenyl)pro...)
Affinity DataKi:  2.5nMAssay Description:Enzyme activities were assayed by monitoring the hydrolysis of substrate in the presence or absence of inhibitor compounds. The hydrolysis was record...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin I(Plasmodium falciparum)
LinköPing University

Curated by ChEMBL
LigandPNGBDBM8015((2S)-N-[(2S,3S)-4-{[(1S)-1-carbamoyl-2-(4-phenylph...)
Affinity DataKi:  2.60nMAssay Description:Enzyme activities were assayed by monitoring the hydrolysis of substrate in the presence or absence of inhibitor compounds. The hydrolysis was record...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin I(Plasmodium falciparum)
LinköPing University

Curated by ChEMBL
LigandPNGBDBM50169113(CHEMBL371182 | Pyridine-2-carboxylic acid {(S)-1-[...)
Affinity DataKi:  2.70nMAssay Description:Inhibitory concentration against the Plasmepsin I of Plasmodium falciparumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin I(Plasmodium falciparum)
LinköPing University

Curated by ChEMBL
LigandPNGBDBM50169102(CHEMBL189976 | N-{(1S,2S)-1-(4-Benzo[1,3]dioxol-5-...)
Affinity DataKi:  3.30nMAssay Description:Inhibitory concentration against the Plasmepsin I of Plasmodium falciparumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin I(Plasmodium falciparum)
LinköPing University

Curated by ChEMBL
LigandPNGBDBM7988((3S,4S)-5-[(4-bromophenyl)methoxy]-N-[(1S)-1-{[(1S...)
Affinity DataKi:  3.40nMAssay Description:Enzyme activities were assayed by monitoring the hydrolysis of substrate in the presence or absence of inhibitor compounds. The hydrolysis was record...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin I(Plasmodium falciparum)
LinköPing University

Curated by ChEMBL
LigandPNGBDBM7988((3S,4S)-5-[(4-bromophenyl)methoxy]-N-[(1S)-1-{[(1S...)
Affinity DataKi:  3.40nMAssay Description:Inhibitory concentration against the Plasmepsin I of Plasmodium falciparumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin I(Plasmodium falciparum)
LinköPing University

Curated by ChEMBL
LigandPNGBDBM8011((2R,3R,4R,5R)-N1,N6-Bis[(1S,2R)-2-hydroxy-1-indany...)
Affinity DataKi:  3.70nMAssay Description:Enzyme activities were assayed by monitoring the hydrolysis of substrate in the presence or absence of inhibitor compounds. The hydrolysis was record...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin I(Plasmodium falciparum)
LinköPing University

Curated by ChEMBL
LigandPNGBDBM7979((3S,4S)-5-[(4-bromophenyl)methoxy]-N-(cyclohexylme...)
Affinity DataKi:  3.90nMAssay Description:Enzyme activities were assayed by monitoring the hydrolysis of substrate in the presence or absence of inhibitor compounds. The hydrolysis was record...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin I(Plasmodium falciparum)
LinköPing University

Curated by ChEMBL
LigandPNGBDBM7983((3S,4S)-5-[(4-bromophenyl)methoxy]-N-cyclohexyl-3-...)
Affinity DataKi:  4.10nMAssay Description:Enzyme activities were assayed by monitoring the hydrolysis of substrate in the presence or absence of inhibitor compounds. The hydrolysis was record...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin I(Plasmodium falciparum)
LinköPing University

Curated by ChEMBL
LigandPNGBDBM8111((2S)-N-[(2S,3S)-4-{[(1S)-2-[4-(1-benzofuran-2-yl)p...)
Affinity DataKi:  4.10nMAssay Description:Enzyme activities were assayed by monitoring the hydrolysis of substrate in the presence or absence of inhibitor compounds. The hydrolysis was record...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlasmepsin I(Plasmodium falciparum)
LinköPing University

Curated by ChEMBL
LigandPNGBDBM8010((2R,3R,4R,5R)-3,4-dihydroxy-N,N'-bis[(1S,2R)-2-hyd...)
Affinity DataKi:  4.40nMAssay Description:Enzyme activities were assayed by monitoring the hydrolysis of substrate in the presence or absence of inhibitor compounds. The hydrolysis was record...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin I(Plasmodium falciparum)
LinköPing University

Curated by ChEMBL
LigandPNGBDBM8010((2R,3R,4R,5R)-3,4-dihydroxy-N,N'-bis[(1S,2R)-2-hyd...)
Affinity DataKi:  4.40nMAssay Description:Enzyme activities were assayed by monitoring the hydrolysis of substrate in the presence or absence of inhibitor compounds. The hydrolysis was record...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin I(Plasmodium falciparum)
LinköPing University

Curated by ChEMBL
LigandPNGBDBM8084((2S)-N-[(2S,3S)-4-{[(1S)-2-(4-bromophenyl)-1-carba...)
Affinity DataKi:  4.70nMAssay Description:Enzyme activities were assayed by monitoring the hydrolysis of substrate in the presence or absence of inhibitor compounds. The hydrolysis was record...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin I(Plasmodium falciparum)
LinköPing University

Curated by ChEMBL
LigandPNGBDBM8109((2S)-N-[(2S,3S)-4-{[(1S)-2-[4-(2H-1,3-benzodioxol-...)
Affinity DataKi:  4.80nMAssay Description:Enzyme activities were assayed by monitoring the hydrolysis of substrate in the presence or absence of inhibitor compounds. The hydrolysis was record...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin I(Plasmodium falciparum)
LinköPing University

Curated by ChEMBL
LigandPNGBDBM7976((3S,4S)-5-(benzyloxy)-N-[(1S)-1-{[(1S)-1-carbamoyl...)
Affinity DataKi:  5.40nMAssay Description:Enzyme activities were assayed by monitoring the hydrolysis of substrate in the presence or absence of inhibitor compounds. The hydrolysis was record...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin I(Plasmodium falciparum)
LinköPing University

Curated by ChEMBL
LigandPNGBDBM7978((3S,4S)-5-[(4-bromophenyl)methoxy]-3-hydroxy-4-[(2...)
Affinity DataKi:  5.40nMAssay Description:Enzyme activities were assayed by monitoring the hydrolysis of substrate in the presence or absence of inhibitor compounds. The hydrolysis was record...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin I(Plasmodium falciparum)
LinköPing University

Curated by ChEMBL
LigandPNGBDBM8004((2R,3R,4R,5R)-3,4-dihydroxy-N,N'-bis[(1S,2R)-2-hyd...)
Affinity DataKi:  5.80nMAssay Description:Enzyme activities were assayed by monitoring the hydrolysis of substrate in the presence or absence of inhibitor compounds. The hydrolysis was record...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin I(Plasmodium falciparum)
LinköPing University

Curated by ChEMBL
LigandPNGBDBM50169111(CHEMBL365935 | N-{(1S,2S)-1-(Biphenyl-4-ylmethoxym...)
Affinity DataKi:  5.90nMAssay Description:Inhibitory concentration against the Plasmepsin I of Plasmodium falciparumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin I(Plasmodium falciparum)
LinköPing University

Curated by ChEMBL
LigandPNGBDBM50173737((2R,3R,4R,5R)-2,5-Bis-((E)-3-benzo[1,3]dioxol-5-yl...)
Affinity DataKi:  6nMAssay Description:Inhibition constant against plasmepsin 1 of Plasmodium falciparum, 10 min using 3 uM of DABCYL-Glu-Arg-Nle-Phe-Le u-Ser-Phe-Pro-EDANS as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin I(Plasmodium falciparum)
LinköPing University

Curated by ChEMBL
LigandPNGBDBM7986((3S,4S)-5-[(4-bromophenyl)methoxy]-N-[(1S)-1-{[(1S...)
Affinity DataKi:  6.40nMAssay Description:Enzyme activities were assayed by monitoring the hydrolysis of substrate in the presence or absence of inhibitor compounds. The hydrolysis was record...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin I(Plasmodium falciparum)
LinköPing University

Curated by ChEMBL
LigandPNGBDBM7981((3S,4S)-5-[(4-bromophenyl)methoxy]-3-hydroxy-N-[2-...)
Affinity DataKi:  6.70nMAssay Description:Enzyme activities were assayed by monitoring the hydrolysis of substrate in the presence or absence of inhibitor compounds. The hydrolysis was record...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin I(Plasmodium falciparum)
LinköPing University

Curated by ChEMBL
LigandPNGBDBM8012((2R,3R,4R,5R)-3,4-dihydroxy-N,N'-bis[(1S,2R)-2-hyd...)
Affinity DataKi:  7.20nMAssay Description:Enzyme activities were assayed by monitoring the hydrolysis of substrate in the presence or absence of inhibitor compounds. The hydrolysis was record...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin I(Plasmodium falciparum)
LinköPing University

Curated by ChEMBL
LigandPNGBDBM7985((3S,4S)-5-[(4-bromophenyl)methoxy]-N-butyl-3-hydro...)
Affinity DataKi:  8.10nMAssay Description:Inhibitory concentration against the Plasmepsin I of Plasmodium falciparumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin I(Plasmodium falciparum)
LinköPing University

Curated by ChEMBL
LigandPNGBDBM7985((3S,4S)-5-[(4-bromophenyl)methoxy]-N-butyl-3-hydro...)
Affinity DataKi:  8.10nMAssay Description:Enzyme activities were assayed by monitoring the hydrolysis of substrate in the presence or absence of inhibitor compounds. The hydrolysis was record...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin I(Plasmodium falciparum)
LinköPing University

Curated by ChEMBL
LigandPNGBDBM8006((2R,3R,4R,5R)-2,5-bis({[(2E)-3-(2,4-dimethoxypyrim...)
Affinity DataKi:  8.40nMAssay Description:Enzyme activities were assayed by monitoring the hydrolysis of substrate in the presence or absence of inhibitor compounds. The hydrolysis was record...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlasmepsin I(Plasmodium falciparum)
LinköPing University

Curated by ChEMBL
LigandPNGBDBM7982((3S,4S)-5-[(4-bromophenyl)methoxy]-3-hydroxy-4-[(2...)
Affinity DataKi:  8.90nMAssay Description:Enzyme activities were assayed by monitoring the hydrolysis of substrate in the presence or absence of inhibitor compounds. The hydrolysis was record...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin I(Plasmodium falciparum)
LinköPing University

Curated by ChEMBL
LigandPNGBDBM50173736((2R,3R,4R,5R)-2,5-Bis-((E)-3-bromo-allyloxy)-3,4-d...)
Affinity DataKi:  9nMAssay Description:Inhibition constant against plasmepsin 1 of Plasmodium falciparum, 10 min using 3 uM of DABCYL-Glu-Arg-Nle-Phe-Le u-Ser-Phe-Pro-EDANS as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin I(Plasmodium falciparum)
LinköPing University

Curated by ChEMBL
LigandPNGBDBM50200015((S)-2-(2S-(4-(4-(((2S,3S)-1-((3S,4S)-1-(butylamino...)
Affinity DataKi:  11nMAssay Description:Inhibition of Plasmodium falciparum recombinant PLM1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin I(Plasmodium falciparum)
LinköPing University

Curated by ChEMBL
LigandPNGBDBM50173749((2R,3R,4R,5R)-2,5-Bis-((E)-3-bromo-allyloxy)-3,4-d...)
Affinity DataKi:  11nMAssay Description:Inhibition constant against plasmepsin 1 of Plasmodium falciparum, 10 min using 3 uM of DABCYL-Glu-Arg-Nle-Phe-Le u-Ser-Phe-Pro-EDANS as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin I(Plasmodium falciparum)
LinköPing University

Curated by ChEMBL
LigandPNGBDBM8108((2S)-N-[(2S,3S)-4-{[(1S)-2-[4-(2H-1,3-benzodioxol-...)
Affinity DataKi:  12nMAssay Description:Enzyme activities were assayed by monitoring the hydrolysis of substrate in the presence or absence of inhibitor compounds. The hydrolysis was record...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlasmepsin I(Plasmodium falciparum)
LinköPing University

Curated by ChEMBL
LigandPNGBDBM8092((2S)-N-[(2S,3S)-4-{[(1S)-1-carbamoyl-2-(4-phenylph...)
Affinity DataKi:  12nMAssay Description:Enzyme activities were assayed by monitoring the hydrolysis of substrate in the presence or absence of inhibitor compounds. The hydrolysis was record...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin I(Plasmodium falciparum)
LinköPing University

Curated by ChEMBL
LigandPNGBDBM8102((2S)-N-[(2S,3S)-4-{[(1S)-2-[4-(1-benzofuran-2-yl)p...)
Affinity DataKi:  13nMAssay Description:Enzyme activities were assayed by monitoring the hydrolysis of substrate in the presence or absence of inhibitor compounds. The hydrolysis was record...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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