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Found 24 Enz. Inhib. hit(s) with all data for entry = 2991
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Valeant Pharmaceuticals Research And Development

LigandPNGBDBM26673(6-(5-bromo-2-hydroxyphenyl)-2-oxo-4-phenyl-1,2-dih...)
Affinity DataIC50:  50nMpH: 7.5 T: 2°CAssay Description:PIM-1 kinase activity was evaluated using calf thymus histones as the substrate in a 96-well filter plate format. After incubation, the plate was was...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Valeant Pharmaceuticals Research And Development

LigandPNGBDBM26674(6-(2-hydroxy-5-methylphenyl)-2-oxo-4-phenyl-1,2-di...)
Affinity DataIC50:  340nMpH: 7.5 T: 2°CAssay Description:PIM-1 kinase activity was evaluated using calf thymus histones as the substrate in a 96-well filter plate format. After incubation, the plate was was...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Valeant Pharmaceuticals Research And Development

LigandPNGBDBM26675(4-(2-hydroxy-5-methylphenyl)-2-oxo-6-phenyl-1,2-di...)
Affinity DataIC50:  370nMpH: 7.5 T: 2°CAssay Description:PIM-1 kinase activity was evaluated using calf thymus histones as the substrate in a 96-well filter plate format. After incubation, the plate was was...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Valeant Pharmaceuticals Research And Development

LigandPNGBDBM26676(6-(2-hydroxyphenyl)-4-(4-hydroxyphenyl)-2-oxo-1,2-...)
Affinity DataIC50:  430nMpH: 7.5 T: 2°CAssay Description:PIM-1 kinase activity was evaluated using calf thymus histones as the substrate in a 96-well filter plate format. After incubation, the plate was was...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Valeant Pharmaceuticals Research And Development

LigandPNGBDBM26684(4-oxo-6-(thiophen-2-yl)-9-oxa-3-azatricyclo[8.4.0....)
Affinity DataIC50:  460nMpH: 7.5 T: 2°CAssay Description:PIM-1 kinase activity was evaluated using calf thymus histones as the substrate in a 96-well filter plate format. After incubation, the plate was was...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Valeant Pharmaceuticals Research And Development

LigandPNGBDBM26685(6-(furan-2-yl)-4-oxo-9-oxa-3-azatricyclo[8.4.0.0^{...)
Affinity DataIC50:  870nMpH: 7.5 T: 2°CAssay Description:PIM-1 kinase activity was evaluated using calf thymus histones as the substrate in a 96-well filter plate format. After incubation, the plate was was...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Valeant Pharmaceuticals Research And Development

LigandPNGBDBM26686(6-(4-chlorophenyl)-4-oxo-9-oxa-3-azatricyclo[8.4.0...)
Affinity DataIC50:  920nMpH: 7.5 T: 2°CAssay Description:PIM-1 kinase activity was evaluated using calf thymus histones as the substrate in a 96-well filter plate format. After incubation, the plate was was...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Valeant Pharmaceuticals Research And Development

LigandPNGBDBM26679(2-oxo-4,6-bis(thiophen-2-yl)-1,2-dihydropyridine-3...)
Affinity DataIC50:  990nMpH: 7.5 T: 2°CAssay Description:PIM-1 kinase activity was evaluated using calf thymus histones as the substrate in a 96-well filter plate format. After incubation, the plate was was...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Valeant Pharmaceuticals Research And Development

LigandPNGBDBM26677(4-(3-chlorophenyl)-6-(5-ethyl-2-hydroxyphenyl)-2-o...)
Affinity DataIC50:  1.03E+3nMpH: 7.5 T: 2°CAssay Description:PIM-1 kinase activity was evaluated using calf thymus histones as the substrate in a 96-well filter plate format. After incubation, the plate was was...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Valeant Pharmaceuticals Research And Development

LigandPNGBDBM26678(6-(3-bromo-4-methoxyphenyl)-2-oxo-4-(trifluorometh...)
Affinity DataIC50:  1.14E+3nMpH: 7.5 T: 2°CAssay Description:PIM-1 kinase activity was evaluated using calf thymus histones as the substrate in a 96-well filter plate format. After incubation, the plate was was...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Valeant Pharmaceuticals Research And Development

LigandPNGBDBM26687(6-(2-chlorophenyl)-4-oxo-9-oxa-3-azatricyclo[8.4.0...)
Affinity DataIC50:  1.23E+3nMpH: 7.5 T: 2°CAssay Description:PIM-1 kinase activity was evaluated using calf thymus histones as the substrate in a 96-well filter plate format. After incubation, the plate was was...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Valeant Pharmaceuticals Research And Development

LigandPNGBDBM26691(4-oxo-6-(thiophen-2-yl)-9-thia-3-azatricyclo[8.4.0...)
Affinity DataIC50:  1.49E+3nMpH: 7.5 T: 2°CAssay Description:PIM-1 kinase activity was evaluated using calf thymus histones as the substrate in a 96-well filter plate format. After incubation, the plate was was...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Valeant Pharmaceuticals Research And Development

LigandPNGBDBM26683(2-{3-amino-4-phenyl-1H-pyrazolo[3,4-b]pyridin-6-yl...)
Affinity DataIC50:  1.77E+3nMpH: 7.5 T: 2°CAssay Description:PIM-1 kinase activity was evaluated using calf thymus histones as the substrate in a 96-well filter plate format. After incubation, the plate was was...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Valeant Pharmaceuticals Research And Development

LigandPNGBDBM26680(2-oxo-4-(thiophen-2-yl)-6-(trifluoromethyl)-1,2-di...)
Affinity DataIC50:  3.54E+3nMpH: 7.5 T: 2°CAssay Description:PIM-1 kinase activity was evaluated using calf thymus histones as the substrate in a 96-well filter plate format. After incubation, the plate was was...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Valeant Pharmaceuticals Research And Development

LigandPNGBDBM26682(2-amino-6-(4-hydroxyphenyl)-4-phenylpyridine-3-car...)
Affinity DataIC50:  4.41E+3nMpH: 7.5 T: 2°CAssay Description:PIM-1 kinase activity was evaluated using calf thymus histones as the substrate in a 96-well filter plate format. After incubation, the plate was was...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Valeant Pharmaceuticals Research And Development

LigandPNGBDBM26692(4-oxo-6-(pyridin-3-yl)-9-thia-3-azatricyclo[8.4.0....)
Affinity DataIC50:  4.79E+3nMpH: 7.5 T: 2°CAssay Description:PIM-1 kinase activity was evaluated using calf thymus histones as the substrate in a 96-well filter plate format. After incubation, the plate was was...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Valeant Pharmaceuticals Research And Development

LigandPNGBDBM26681(6-(furan-2-yl)-2-oxo-4-(trifluoromethyl)-1,2-dihyd...)
Affinity DataIC50:  1.60E+4nMpH: 7.5 T: 2°CAssay Description:PIM-1 kinase activity was evaluated using calf thymus histones as the substrate in a 96-well filter plate format. After incubation, the plate was was...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Valeant Pharmaceuticals Research And Development

LigandPNGBDBM26695(4-oxo-6-(pyridin-4-yl)-3-azatricyclo[8.4.0.0^{2,7}...)
Affinity DataIC50: >2.00E+4nMpH: 7.5 T: 2°CAssay Description:PIM-1 kinase activity was evaluated using calf thymus histones as the substrate in a 96-well filter plate format. After incubation, the plate was was...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Valeant Pharmaceuticals Research And Development

LigandPNGBDBM26694(6-(4-fluorophenyl)-4-oxo-9-thia-3-azatricyclo[8.4....)
Affinity DataIC50: >2.00E+4nMpH: 7.5 T: 2°CAssay Description:PIM-1 kinase activity was evaluated using calf thymus histones as the substrate in a 96-well filter plate format. After incubation, the plate was was...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Valeant Pharmaceuticals Research And Development

LigandPNGBDBM26693(6-(2-chlorophenyl)-4-oxo-9-thia-3-azatricyclo[8.4....)
Affinity DataIC50:  2.00E+4nMpH: 7.5 T: 2°CAssay Description:PIM-1 kinase activity was evaluated using calf thymus histones as the substrate in a 96-well filter plate format. After incubation, the plate was was...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Valeant Pharmaceuticals Research And Development

LigandPNGBDBM26689(2-keto-4-(4-pyridyl)-1,5-dihydrochromeno[4,3-b]pyr...)
Affinity DataIC50:  2.00E+4nMpH: 7.5 T: 2°CAssay Description:PIM-1 kinase activity was evaluated using calf thymus histones as the substrate in a 96-well filter plate format. After incubation, the plate was was...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Valeant Pharmaceuticals Research And Development

LigandPNGBDBM26688(6-(4-methoxyphenyl)-4-oxo-9-oxa-3-azatricyclo[8.4....)
Affinity DataIC50: >2.00E+4nMpH: 7.5 T: 2°CAssay Description:PIM-1 kinase activity was evaluated using calf thymus histones as the substrate in a 96-well filter plate format. After incubation, the plate was was...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Valeant Pharmaceuticals Research And Development

LigandPNGBDBM26696(ethyl 3-methyl-4,8-dioxo-9-oxa-3-azatricyclo[8.4.0...)
Affinity DataIC50: >2.00E+4nMpH: 7.5 T: 2°CAssay Description:PIM-1 kinase activity was evaluated using calf thymus histones as the substrate in a 96-well filter plate format. After incubation, the plate was was...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Valeant Pharmaceuticals Research And Development

LigandPNGBDBM26690(4-oxo-6-(pyridin-2-yl)-9-oxa-3-azatricyclo[8.4.0.0...)
Affinity DataIC50: >2.00E+4nMpH: 7.5 T: 2°CAssay Description:PIM-1 kinase activity was evaluated using calf thymus histones as the substrate in a 96-well filter plate format. After incubation, the plate was was...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed