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Found 111 Enz. Inhib. hit(s) with all data for entry = 50034943
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071159((2R,4R)-4-Amino-1-naphthalen-1-ylmethyl-pyrrolidin...)
Affinity DataIC50:  8.58E+3nMAssay Description:In vitro antagonist activity at recombinant human Metabotropic glutamate receptor 3 expressed in RGT cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071150((2R,4R)-4-Amino-1-biphenyl-2-ylmethyl-pyrrolidine-...)
Affinity DataIC50:  1.61E+4nMAssay Description:In vitro antagonist activity at recombinant human Metabotropic glutamate receptor 3 expressed in RGT cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071159((2R,4R)-4-Amino-1-naphthalen-1-ylmethyl-pyrrolidin...)
Affinity DataIC50:  2.00E+4nMAssay Description:In vitro antagonist activity at recombinant human Metabotropic glutamate receptor 2 expressed in RGT cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50049748((2S,4S)-2-Amino-4-(4,4-diphenyl-butyl)-pentanedioi...)
Affinity DataIC50:  3.00E+4nMAssay Description:In vitro antagonist activity at recombinant human Metabotropic glutamate receptor 3 expressed in RGT cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071150((2R,4R)-4-Amino-1-biphenyl-2-ylmethyl-pyrrolidine-...)
Affinity DataIC50:  3.60E+4nMAssay Description:In vitro antagonist activity at recombinant human Metabotropic glutamate receptor 1 expressed in RGT cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071151((2R,4R)-4-Amino-1-(2,2-diphenyl-ethyl)-pyrrolidine...)
Affinity DataIC50:  3.73E+4nMAssay Description:In vitro antagonist activity at recombinant human Metabotropic glutamate receptor 2 expressed in RGT cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071167((2R,4R)-4-Amino-1-(2,6-dichloro-benzyl)-pyrrolidin...)
Affinity DataIC50:  4.03E+4nMAssay Description:In vitro antagonist activity at recombinant human Metabotropic glutamate receptor 3 expressed in RGT cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071167((2R,4R)-4-Amino-1-(2,6-dichloro-benzyl)-pyrrolidin...)
Affinity DataIC50:  4.20E+4nMAssay Description:In vitro antagonist activity at recombinant human Metabotropic glutamate receptor 2 expressed in RGT cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071160((2R,4R)-4-Amino-1-cyclohexylmethyl-pyrrolidine-2,4...)
Affinity DataIC50:  4.62E+4nMAssay Description:In vitro antagonist activity at recombinant human Metabotropic glutamate receptor 2 expressed in RGT cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50049748((2S,4S)-2-Amino-4-(4,4-diphenyl-butyl)-pentanedioi...)
Affinity DataIC50:  5.00E+4nMAssay Description:In vitro antagonist activity at recombinant human Metabotropic glutamate receptor 2 expressed in RGT cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071155((2R,4R)-4-Amino-1-naphthalen-2-ylmethyl-pyrrolidin...)
Affinity DataIC50:  5.00E+4nMAssay Description:In vitro antagonist activity at recombinant human Metabotropic glutamate receptor 2 expressed in RGT cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071162(4-((S)-1-Carboxy-ethylamino)-benzoic acid | CHEMBL...)
Affinity DataIC50:  5.70E+4nMAssay Description:In vitro antagonist activity at recombinant human Metabotropic glutamate receptor 1 expressed in RGT cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071152((2R,4R)-4-Amino-1-phenethyl-pyrrolidine-2,4-dicarb...)
Affinity DataIC50:  6.10E+4nMAssay Description:In vitro antagonist activity at recombinant human Metabotropic glutamate receptor 2 expressed in RGT cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071151((2R,4R)-4-Amino-1-(2,2-diphenyl-ethyl)-pyrrolidine...)
Affinity DataIC50:  6.36E+4nMAssay Description:In vitro antagonist activity at recombinant human Metabotropic glutamate receptor 3 expressed in RGT cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071165((2R,4R)-4-Amino-1-(2-chloro-benzyl)-pyrrolidine-2,...)
Affinity DataIC50:  7.50E+4nMAssay Description:In vitro antagonist activity at recombinant human Metabotropic glutamate receptor 2 expressed in RGT cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071163((2R,4R)-4-Amino-1-(3,4-dichloro-benzyl)-pyrrolidin...)
Affinity DataIC50:  9.90E+4nMAssay Description:In vitro antagonist activity at recombinant Metabotropic glutamate receptor 5 expressed in RGT cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071161((2R,4R)-4-Amino-1-benzyl-pyrrolidine-2,4-dicarboxy...)
Affinity DataIC50:  1.21E+5nMAssay Description:In vitro antagonist activity at recombinant human Metabotropic glutamate receptor 2 expressed in RGT cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071155((2R,4R)-4-Amino-1-naphthalen-2-ylmethyl-pyrrolidin...)
Affinity DataIC50:  1.33E+5nMAssay Description:In vitro antagonist activity at recombinant human Metabotropic glutamate receptor 1 expressed in RGT cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071152((2R,4R)-4-Amino-1-phenethyl-pyrrolidine-2,4-dicarb...)
Affinity DataIC50:  1.66E+5nMAssay Description:In vitro antagonist activity at recombinant human Metabotropic glutamate receptor 3 expressed in RGT cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071162(4-((S)-1-Carboxy-ethylamino)-benzoic acid | CHEMBL...)
Affinity DataIC50:  1.95E+5nMAssay Description:In vitro antagonist activity at recombinant Metabotropic glutamate receptor 5 expressed in RGT cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071167((2R,4R)-4-Amino-1-(2,6-dichloro-benzyl)-pyrrolidin...)
Affinity DataIC50:  2.39E+5nMAssay Description:In vitro antagonist activity at recombinant human Metabotropic glutamate receptor 1 expressed in RGT cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071161((2R,4R)-4-Amino-1-benzyl-pyrrolidine-2,4-dicarboxy...)
Affinity DataIC50: >3.00E+5nMAssay Description:In vitro antagonist activity at recombinant human Metabotropic glutamate receptor 1 expressed in RGT cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071150((2R,4R)-4-Amino-1-biphenyl-2-ylmethyl-pyrrolidine-...)
Affinity DataIC50: >3.00E+5nMAssay Description:In vitro antagonist activity at recombinant Metabotropic glutamate receptor 5 expressed in RGT cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071161((2R,4R)-4-Amino-1-benzyl-pyrrolidine-2,4-dicarboxy...)
Affinity DataIC50: >3.00E+5nMAssay Description:In vitro antagonist activity at recombinant Metabotropic glutamate receptor 5 expressed in RGT cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071161((2R,4R)-4-Amino-1-benzyl-pyrrolidine-2,4-dicarboxy...)
Affinity DataIC50: >3.00E+5nMAssay Description:In vitro antagonist activity at recombinant human Metabotropic glutamate receptor 2 expressed in RGT cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071161((2R,4R)-4-Amino-1-benzyl-pyrrolidine-2,4-dicarboxy...)
Affinity DataIC50: >3.00E+5nMAssay Description:In vitro antagonist activity at recombinant human Metabotropic glutamate receptor 4 expressed in RGT cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50366533(CHEMBL1169414)
Affinity DataIC50: >3.00E+5nMAssay Description:In vitro antagonist activity at recombinant Metabotropic glutamate receptor 5 expressed in RGT cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071152((2R,4R)-4-Amino-1-phenethyl-pyrrolidine-2,4-dicarb...)
Affinity DataIC50: >3.00E+5nMAssay Description:In vitro antagonist activity at recombinant Metabotropic glutamate receptor 5 expressed in RGT cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071153((2R,4R)-4-Amino-1-(2,4-dichloro-benzyl)-pyrrolidin...)
Affinity DataIC50: >3.00E+5nMAssay Description:In vitro antagonist activity at recombinant Metabotropic glutamate receptor 5 expressed in RGT cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50366533(CHEMBL1169414)
Affinity DataIC50: >3.00E+5nMAssay Description:In vitro antagonist activity at recombinant human Metabotropic glutamate receptor 1 expressed in RGT cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071152((2R,4R)-4-Amino-1-phenethyl-pyrrolidine-2,4-dicarb...)
Affinity DataIC50: >3.00E+5nMAssay Description:In vitro antagonist activity at recombinant human Metabotropic glutamate receptor 1 expressed in RGT cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071150((2R,4R)-4-Amino-1-biphenyl-2-ylmethyl-pyrrolidine-...)
Affinity DataIC50: >3.00E+5nMAssay Description:In vitro antagonist activity at recombinant human Metabotropic glutamate receptor 2 expressed in RGT cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071154((2R,4R)-4-Amino-1-(3-phenyl-propyl)-pyrrolidine-2,...)
Affinity DataIC50: >3.00E+5nMAssay Description:In vitro antagonist activity at recombinant human Metabotropic glutamate receptor 1 expressed in RGT cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071158((2R,4R)-4-Amino-1-biphenyl-4-ylmethyl-pyrrolidine-...)
Affinity DataIC50: >3.00E+5nMAssay Description:In vitro antagonist activity at recombinant Metabotropic glutamate receptor 5 expressed in RGT cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071157((2R,4R)-4-Amino-1-(4-chloro-benzyl)-pyrrolidine-2,...)
Affinity DataIC50: >3.00E+5nMAssay Description:In vitro antagonist activity at recombinant Metabotropic glutamate receptor 5 expressed in RGT cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071156((2R,4R)-4-Amino-1-ethyl-pyrrolidine-2,4-dicarboxyl...)
Affinity DataIC50: >3.00E+5nMAssay Description:In vitro antagonist activity at recombinant human Metabotropic glutamate receptor 1 expressed in RGT cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071153((2R,4R)-4-Amino-1-(2,4-dichloro-benzyl)-pyrrolidin...)
Affinity DataIC50: >3.00E+5nMAssay Description:In vitro antagonist activity at recombinant human Metabotropic glutamate receptor 1 expressed in RGT cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071160((2R,4R)-4-Amino-1-cyclohexylmethyl-pyrrolidine-2,4...)
Affinity DataIC50: >3.00E+5nMAssay Description:In vitro antagonist activity at recombinant human Metabotropic glutamate receptor 1 expressed in RGT cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071151((2R,4R)-4-Amino-1-(2,2-diphenyl-ethyl)-pyrrolidine...)
Affinity DataIC50: >3.00E+5nMAssay Description:In vitro antagonist activity at recombinant Metabotropic glutamate receptor 5 expressed in RGT cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071160((2R,4R)-4-Amino-1-cyclohexylmethyl-pyrrolidine-2,4...)
Affinity DataIC50: >3.00E+5nMAssay Description:In vitro antagonist activity at recombinant human Metabotropic glutamate receptor 3 expressed in RGT cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071150((2R,4R)-4-Amino-1-biphenyl-2-ylmethyl-pyrrolidine-...)
Affinity DataIC50: >3.00E+5nMAssay Description:In vitro antagonist activity at recombinant human Metabotropic glutamate receptor 4 expressed in RGT cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 8(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071156((2R,4R)-4-Amino-1-ethyl-pyrrolidine-2,4-dicarboxyl...)
Affinity DataIC50: >3.00E+5nMAssay Description:In vitro antagonist activity at recombinant Metabotropic glutamate receptor 8 expressed in RGT cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071163((2R,4R)-4-Amino-1-(3,4-dichloro-benzyl)-pyrrolidin...)
Affinity DataIC50: >3.00E+5nMAssay Description:In vitro antagonist activity at recombinant human Metabotropic glutamate receptor 1 expressed in RGT cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071164((2R,4R)-4-Amino-1-methyl-pyrrolidine-2,4-dicarboxy...)
Affinity DataIC50: >3.00E+5nMAssay Description:In vitro antagonist activity at recombinant human Metabotropic glutamate receptor 1 expressed in RGT cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071165((2R,4R)-4-Amino-1-(2-chloro-benzyl)-pyrrolidine-2,...)
Affinity DataIC50: >3.00E+5nMAssay Description:In vitro antagonist activity at recombinant human Metabotropic glutamate receptor 1 expressed in RGT cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071158((2R,4R)-4-Amino-1-biphenyl-4-ylmethyl-pyrrolidine-...)
Affinity DataIC50: >3.00E+5nMAssay Description:In vitro antagonist activity at recombinant human Metabotropic glutamate receptor 2 expressed in RGT cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071165((2R,4R)-4-Amino-1-(2-chloro-benzyl)-pyrrolidine-2,...)
Affinity DataIC50: >3.00E+5nMAssay Description:In vitro antagonist activity at recombinant human Metabotropic glutamate receptor 4 expressed in RGT cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071151((2R,4R)-4-Amino-1-(2,2-diphenyl-ethyl)-pyrrolidine...)
Affinity DataIC50: >3.00E+5nMAssay Description:In vitro antagonist activity at recombinant human Metabotropic glutamate receptor 4 expressed in RGT cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071159((2R,4R)-4-Amino-1-naphthalen-1-ylmethyl-pyrrolidin...)
Affinity DataIC50: >3.00E+5nMAssay Description:In vitro antagonist activity at recombinant human Metabotropic glutamate receptor 1 expressed in RGT cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071154((2R,4R)-4-Amino-1-(3-phenyl-propyl)-pyrrolidine-2,...)
Affinity DataIC50: >3.00E+5nMAssay Description:In vitro antagonist activity at recombinant Metabotropic glutamate receptor 5 expressed in RGT cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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