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Compile Data Set for Download or QSAR

Found 105 hits Enz. Inhib. hit(s) with all data for entry = 50041142   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Beta-1 adrenergic receptor


(GUINEA PIG)
BDBM50405431
PNG
(CHEMBL275934)
Show SMILES COc1ccc(CCNCC(O)COc2ccc(OCc3ncc[nH]3)cc2)cc1OC
Show InChI InChI=1S/C23H29N3O5/c1-28-21-8-3-17(13-22(21)29-2)9-10-24-14-18(27)15-30-19-4-6-20(7-5-19)31-16-23-25-11-12-26-23/h3-8,11-13,18,24,27H,9-10,14-16H2,1-2H3,(H,25,26)
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n/an/an/a 17n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against beta-1 adrenergic receptor measured by inhibition of positive chronotropic effect of isoproterenolin in isolated...


J Med Chem 29: 1065-80 (1986)


Article DOI: 10.1021/jm00156a028
BindingDB Entry DOI: 10.7270/Q2BP0408
More data for this
Ligand-Target Pair
Beta-1 adrenergic receptor


(GUINEA PIG)
BDBM50405425
PNG
(CHEMBL11224)
Show SMILES COc1ccc(CCNCC(O)COc2ccc(cc2)-c2nc(C)c(Cl)[nH]2)cc1OC
Show InChI InChI=1S/C23H28ClN3O4/c1-15-22(24)27-23(26-15)17-5-7-19(8-6-17)31-14-18(28)13-25-11-10-16-4-9-20(29-2)21(12-16)30-3/h4-9,12,18,25,28H,10-11,13-14H2,1-3H3,(H,26,27)
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n/an/an/a 7.90n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against beta-1 adrenergic receptor measured by inhibition of positive chronotropic effect of isoproterenolin in isolated...


J Med Chem 29: 1065-80 (1986)


Article DOI: 10.1021/jm00156a028
BindingDB Entry DOI: 10.7270/Q2BP0408
More data for this
Ligand-Target Pair
Beta-1 adrenergic receptor


(GUINEA PIG)
BDBM50405415
PNG
(CHEMBL442522)
Show SMILES COc1ccc(CCNCC(O)COc2ccc(cc2)-c2ncc(CN3CCOCC3)[nH]2)cc1OC
Show InChI InChI=1S/C27H36N4O5/c1-33-25-8-3-20(15-26(25)34-2)9-10-28-17-23(32)19-36-24-6-4-21(5-7-24)27-29-16-22(30-27)18-31-11-13-35-14-12-31/h3-8,15-16,23,28,32H,9-14,17-19H2,1-2H3,(H,29,30)
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n/an/an/a 19n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against beta-1 adrenergic receptor measured by inhibition of positive chronotropic effect of isoproterenolin in isolated...


J Med Chem 29: 1065-80 (1986)


Article DOI: 10.1021/jm00156a028
BindingDB Entry DOI: 10.7270/Q2BP0408
More data for this
Ligand-Target Pair
Beta-1 adrenergic receptor


(GUINEA PIG)
BDBM50405432
PNG
(CHEMBL269467)
Show SMILES COc1ccc(CCNCC(O)COc2ccc(Cc3ncc(C)[nH]3)cc2)cc1OC
Show InChI InChI=1S/C24H31N3O4/c1-17-14-26-24(27-17)13-18-4-7-21(8-5-18)31-16-20(28)15-25-11-10-19-6-9-22(29-2)23(12-19)30-3/h4-9,12,14,20,25,28H,10-11,13,15-16H2,1-3H3,(H,26,27)
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n/an/an/a 22n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against beta-1 adrenergic receptor measured by inhibition of positive chronotropic effect of isoproterenolin in isolated...


J Med Chem 29: 1065-80 (1986)


Article DOI: 10.1021/jm00156a028
BindingDB Entry DOI: 10.7270/Q2BP0408
More data for this
Ligand-Target Pair
Beta-1 adrenergic receptor


(GUINEA PIG)
BDBM25748
PNG
(3-(2-{[3-(2-cyanophenoxy)-2-hydroxypropyl]amino}et...)
Show SMILES OC(CNCCNC(=O)Nc1ccccc1)COc1ccccc1C#N
Show InChI InChI=1S/C19H22N4O3/c20-12-15-6-4-5-9-18(15)26-14-17(24)13-21-10-11-22-19(25)23-16-7-2-1-3-8-16/h1-9,17,21,24H,10-11,13-14H2,(H2,22,23,25)
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n/an/an/a 0.933n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against beta-1 adrenergic receptor measured by inhibition of positive chronotropic effect of isoproterenolin in isolated...


J Med Chem 29: 1065-80 (1986)


Article DOI: 10.1021/jm00156a028
BindingDB Entry DOI: 10.7270/Q2BP0408
More data for this
Ligand-Target Pair
Beta-1 adrenergic receptor


(GUINEA PIG)
BDBM50405426
PNG
(CHEMBL11219)
Show SMILES CCCCNC(=O)NCCNCC(O)COc1ccc(cc1)-c1nc(C)c[nH]1
Show InChI InChI=1S/C20H31N5O3/c1-3-4-9-22-20(27)23-11-10-21-13-17(26)14-28-18-7-5-16(6-8-18)19-24-12-15(2)25-19/h5-8,12,17,21,26H,3-4,9-11,13-14H2,1-2H3,(H,24,25)(H2,22,23,27)
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n/an/an/a 93n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against beta-1 adrenergic receptor measured by inhibition of positive chronotropic effect of isoproterenolin in isolated...


J Med Chem 29: 1065-80 (1986)


Article DOI: 10.1021/jm00156a028
BindingDB Entry DOI: 10.7270/Q2BP0408
More data for this
Ligand-Target Pair
Beta-1 adrenergic receptor


(GUINEA PIG)
BDBM50405402
PNG
(CHEMBL11080)
Show SMILES COc1ccc(CCNCC(O)COc2ccc(COCc3ncc[nH]3)cc2)cc1OC
Show InChI InChI=1S/C24H31N3O5/c1-29-22-8-5-18(13-23(22)30-2)9-10-25-14-20(28)16-32-21-6-3-19(4-7-21)15-31-17-24-26-11-12-27-24/h3-8,11-13,20,25,28H,9-10,14-17H2,1-2H3,(H,26,27)
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n/an/an/a 6.90n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against beta-1 adrenergic receptor measured by inhibition of positive chronotropic effect of isoproterenolin in isolated...


J Med Chem 29: 1065-80 (1986)


Article DOI: 10.1021/jm00156a028
BindingDB Entry DOI: 10.7270/Q2BP0408
More data for this
Ligand-Target Pair
Beta-1 adrenergic receptor


(GUINEA PIG)
BDBM50405421
PNG
(CHEMBL415970)
Show SMILES COc1ccc(CCNCC(O)COc2ccc(CCc3nc(c[nH]3)-c3cccs3)cc2)cc1OC
Show InChI InChI=1S/C28H33N3O4S/c1-33-25-11-7-21(16-26(25)34-2)13-14-29-17-22(32)19-35-23-9-5-20(6-10-23)8-12-28-30-18-24(31-28)27-4-3-15-36-27/h3-7,9-11,15-16,18,22,29,32H,8,12-14,17,19H2,1-2H3,(H,30,31)
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n/an/an/a 3.10n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against beta-1 adrenergic receptor measured by inhibition of positive chronotropic effect of isoproterenolin in isolated...


J Med Chem 29: 1065-80 (1986)


Article DOI: 10.1021/jm00156a028
BindingDB Entry DOI: 10.7270/Q2BP0408
More data for this
Ligand-Target Pair
Beta-1 adrenergic receptor


(GUINEA PIG)
BDBM50292219
PNG
((-)-3-morpholino-4-(3-tert-butylamino-2-hydroxypro...)
Show SMILES CC(C)(C)NC[C@H](O)COc1nsnc1N1CCOCC1
Show InChI InChI=1S/C13H24N4O3S/c1-13(2,3)14-8-10(18)9-20-12-11(15-21-16-12)17-4-6-19-7-5-17/h10,14,18H,4-9H2,1-3H3/t10-/m0/s1
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n/an/an/a 0.363n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against beta-1 adrenergic receptor measured by inhibition of positive chronotropic effect of isoproterenolin in isolated...


J Med Chem 29: 1065-80 (1986)


Article DOI: 10.1021/jm00156a028
BindingDB Entry DOI: 10.7270/Q2BP0408
More data for this
Ligand-Target Pair
Beta-1 adrenergic receptor


(GUINEA PIG)
BDBM25761
PNG
(Anapriline | Avlocardyl | CHEMBL27 | PROPANOLOL(-)...)
Show SMILES CC(C)NCC(O)COc1cccc2ccccc12
Show InChI InChI=1S/C16H21NO2/c1-12(2)17-10-14(18)11-19-16-9-5-7-13-6-3-4-8-15(13)16/h3-9,12,14,17-18H,10-11H2,1-2H3
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n/an/an/a 1.70n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against beta-1 adrenergic receptor measured by inhibition of positive chronotropic effect of isoproterenolin in isolated...


J Med Chem 29: 1065-80 (1986)


Article DOI: 10.1021/jm00156a028
BindingDB Entry DOI: 10.7270/Q2BP0408
More data for this
Ligand-Target Pair
Beta-1 adrenergic receptor


(GUINEA PIG)
BDBM50405423
PNG
(CHEMBL276029)
Show SMILES COCCc1cnc([nH]1)-c1ccc(OCC(O)CNCCc2ccc(OC)c(OC)c2)cc1
Show InChI InChI=1S/C25H33N3O5/c1-30-13-11-20-15-27-25(28-20)19-5-7-22(8-6-19)33-17-21(29)16-26-12-10-18-4-9-23(31-2)24(14-18)32-3/h4-9,14-15,21,26,29H,10-13,16-17H2,1-3H3,(H,27,28)
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n/an/an/a 44n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against beta-1 adrenergic receptor measured by inhibition of positive chronotropic effect of isoproterenolin in isolated...


J Med Chem 29: 1065-80 (1986)


Article DOI: 10.1021/jm00156a028
BindingDB Entry DOI: 10.7270/Q2BP0408
More data for this
Ligand-Target Pair
Beta-1 adrenergic receptor


(GUINEA PIG)
BDBM50405442
PNG
(CHEMBL11205)
Show SMILES COc1ccc(CCNCC(O)COc2ccc(Cc3nc(c[nH]3)-c3cccs3)cc2)cc1OC
Show InChI InChI=1S/C27H31N3O4S/c1-32-24-10-7-20(14-25(24)33-2)11-12-28-16-21(31)18-34-22-8-5-19(6-9-22)15-27-29-17-23(30-27)26-4-3-13-35-26/h3-10,13-14,17,21,28,31H,11-12,15-16,18H2,1-2H3,(H,29,30)
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n/an/an/a 2.90n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against beta-1 adrenergic receptor measured by inhibition of positive chronotropic effect of isoproterenolin in isolated...


J Med Chem 29: 1065-80 (1986)


Article DOI: 10.1021/jm00156a028
BindingDB Entry DOI: 10.7270/Q2BP0408
More data for this
Ligand-Target Pair
Beta-1 adrenergic receptor


(GUINEA PIG)
BDBM50405433
PNG
(CHEMBL2052005)
Show SMILES CCOCCNC[C@H](O)COc1ccc(cc1)-c1nc(c[nH]1)-c1cccs1
Show InChI InChI=1S/C20H25N3O3S/c1-2-25-10-9-21-12-16(24)14-26-17-7-5-15(6-8-17)20-22-13-18(23-20)19-4-3-11-27-19/h3-8,11,13,16,21,24H,2,9-10,12,14H2,1H3,(H,22,23)/t16-/m0/s1
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n/an/an/a 13n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against beta-1 adrenergic receptor measured by inhibition of positive chronotropic effect of isoproterenolin in isolated...


J Med Chem 29: 1065-80 (1986)


Article DOI: 10.1021/jm00156a028
BindingDB Entry DOI: 10.7270/Q2BP0408
More data for this
Ligand-Target Pair
Beta-1 adrenergic receptor


(GUINEA PIG)
BDBM50404980
PNG
(CHEMBL1788320)
Show SMILES COc1ccc(CCNC[C@H](O)COc2ccc(cc2)-c2nc(c[nH]2)-c2cccs2)cc1OC
Show InChI InChI=1S/C26H29N3O4S/c1-31-23-10-5-18(14-24(23)32-2)11-12-27-15-20(30)17-33-21-8-6-19(7-9-21)26-28-16-22(29-26)25-4-3-13-34-25/h3-10,13-14,16,20,27,30H,11-12,15,17H2,1-2H3,(H,28,29)/t20-/m0/s1
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n/an/an/a 30n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against beta-1 adrenergic receptor measured by inhibition of positive chronotropic effect of isoproterenolin in isolated...


J Med Chem 29: 1065-80 (1986)


Article DOI: 10.1021/jm00156a028
BindingDB Entry DOI: 10.7270/Q2BP0408
More data for this
Ligand-Target Pair
Beta-1 adrenergic receptor


(GUINEA PIG)
BDBM50405408
PNG
(CHEMBL2052004)
Show SMILES COCc1cnc([nH]1)-c1ccc(OC[C@@H](O)CNCCc2ccc(OC)c(OC)c2)cc1
Show InChI InChI=1S/C24H31N3O5/c1-29-15-19-13-26-24(27-19)18-5-7-21(8-6-18)32-16-20(28)14-25-11-10-17-4-9-22(30-2)23(12-17)31-3/h4-9,12-13,20,25,28H,10-11,14-16H2,1-3H3,(H,26,27)/t20-/m0/s1
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n/an/an/a 11n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against beta-1 adrenergic receptor measured by inhibition of positive chronotropic effect of isoproterenolin in isolated...


J Med Chem 29: 1065-80 (1986)


Article DOI: 10.1021/jm00156a028
BindingDB Entry DOI: 10.7270/Q2BP0408
More data for this
Ligand-Target Pair
Beta-1 adrenergic receptor


(GUINEA PIG)
BDBM50405429
PNG
(CHEMBL536552)
Show SMILES COc1ccc(CCNCC(O)COc2ccc(cc2)-c2nccn2C)cc1OC
Show InChI InChI=1S/C23H29N3O4/c1-26-13-12-25-23(26)18-5-7-20(8-6-18)30-16-19(27)15-24-11-10-17-4-9-21(28-2)22(14-17)29-3/h4-9,12-14,19,24,27H,10-11,15-16H2,1-3H3
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n/an/an/a 479n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against beta-1 adrenergic receptor measured by inhibition of positive chronotropic effect of isoproterenolin in isolated...


J Med Chem 29: 1065-80 (1986)


Article DOI: 10.1021/jm00156a028
BindingDB Entry DOI: 10.7270/Q2BP0408
More data for this
Ligand-Target Pair
Beta-1 adrenergic receptor


(GUINEA PIG)
BDBM25756
PNG
((2R,3R)-2,3-dihydroxysuccinic acid;1-(isopropylami...)
Show SMILES COCCc1ccc(OCC(O)CNC(C)C)cc1
Show InChI InChI=1S/C15H25NO3/c1-12(2)16-10-14(17)11-19-15-6-4-13(5-7-15)8-9-18-3/h4-7,12,14,16-17H,8-11H2,1-3H3
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TBA

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against beta-1 adrenergic receptor measured by inhibition of positive chronotropic effect of isoproterenolin in isolated...


J Med Chem 29: 1065-80 (1986)


Article DOI: 10.1021/jm00156a028
BindingDB Entry DOI: 10.7270/Q2BP0408
More data for this
Ligand-Target Pair
Beta-1 adrenergic receptor


(GUINEA PIG)
BDBM50405441
PNG
(CHEMBL11145)
Show SMILES COc1ccc(CCNCC(O)COc2ccc(cc2)-c2nc(c[nH]2)C(C)C)cc1OC
Show InChI InChI=1S/C25H33N3O4/c1-17(2)22-15-27-25(28-22)19-6-8-21(9-7-19)32-16-20(29)14-26-12-11-18-5-10-23(30-3)24(13-18)31-4/h5-10,13,15,17,20,26,29H,11-12,14,16H2,1-4H3,(H,27,28)
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n/an/an/a 1.5n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against beta-1 adrenergic receptor measured by inhibition of positive chronotropic effect of isoproterenolin in isolated...


J Med Chem 29: 1065-80 (1986)


Article DOI: 10.1021/jm00156a028
BindingDB Entry DOI: 10.7270/Q2BP0408
More data for this
Ligand-Target Pair
Beta-1 adrenergic receptor


(GUINEA PIG)
BDBM50405407
PNG
(CHEMBL65774)
Show SMILES COc1ccc(CCNC[C@H](O)COc2ccc(Cc3nc(c[nH]3)C(C)=O)cc2)cc1OC
Show InChI InChI=1S/C25H31N3O5/c1-17(29)22-15-27-25(28-22)13-18-4-7-21(8-5-18)33-16-20(30)14-26-11-10-19-6-9-23(31-2)24(12-19)32-3/h4-9,12,15,20,26,30H,10-11,13-14,16H2,1-3H3,(H,27,28)/t20-/m0/s1
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TBA

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against beta-1 adrenergic receptor measured by inhibition of positive chronotropic effect of isoproterenolin in isolated...


J Med Chem 29: 1065-80 (1986)


Article DOI: 10.1021/jm00156a028
BindingDB Entry DOI: 10.7270/Q2BP0408
More data for this
Ligand-Target Pair
Beta-1 adrenergic receptor


(GUINEA PIG)
BDBM50405430
PNG
(CHEMBL10988)
Show SMILES CC(C)NCC(O)COc1ccc(cc1)-c1nc(c[nH]1)C(C)C
Show InChI InChI=1S/C18H27N3O2/c1-12(2)17-10-20-18(21-17)14-5-7-16(8-6-14)23-11-15(22)9-19-13(3)4/h5-8,10,12-13,15,19,22H,9,11H2,1-4H3,(H,20,21)
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n/an/an/a 10n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against beta-1 adrenergic receptor measured by inhibition of positive chronotropic effect of isoproterenolin in isolated...


J Med Chem 29: 1065-80 (1986)


Article DOI: 10.1021/jm00156a028
BindingDB Entry DOI: 10.7270/Q2BP0408
More data for this
Ligand-Target Pair
Beta-1 adrenergic receptor


(GUINEA PIG)
BDBM50405437
PNG
(CHEMBL11362)
Show SMILES Cc1cnc(Cc2ccc(OCC(O)CNC(C)(C)C)cc2)[nH]1
Show InChI InChI=1S/C18H27N3O2/c1-13-10-19-17(21-13)9-14-5-7-16(8-6-14)23-12-15(22)11-20-18(2,3)4/h5-8,10,15,20,22H,9,11-12H2,1-4H3,(H,19,21)
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TBA

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against beta-1 adrenergic receptor measured by inhibition of positive chronotropic effect of isoproterenolin in isolated...


J Med Chem 29: 1065-80 (1986)


Article DOI: 10.1021/jm00156a028
BindingDB Entry DOI: 10.7270/Q2BP0408
More data for this
Ligand-Target Pair
Beta-1 adrenergic receptor


(GUINEA PIG)
BDBM25753
PNG
(2-{4-[2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl...)
Show SMILES CC(C)NCC(O)COc1ccc(CC(N)=O)cc1
Show InChI InChI=1S/C14H22N2O3/c1-10(2)16-8-12(17)9-19-13-5-3-11(4-6-13)7-14(15)18/h3-6,10,12,16-17H,7-9H2,1-2H3,(H2,15,18)
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n/an/an/a 24n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against beta-1 adrenergic receptor measured by inhibition of positive chronotropic effect of isoproterenolin in isolated...


J Med Chem 29: 1065-80 (1986)


Article DOI: 10.1021/jm00156a028
BindingDB Entry DOI: 10.7270/Q2BP0408
More data for this
Ligand-Target Pair
Beta-1 adrenergic receptor


(GUINEA PIG)
BDBM50405420
PNG
(CHEMBL11427)
Show SMILES COc1ccc(CCNCC(O)COc2ccc(cc2)-c2ncc([nH]2)C(N)=O)cc1OC
Show InChI InChI=1S/C23H28N4O5/c1-30-20-8-3-15(11-21(20)31-2)9-10-25-12-17(28)14-32-18-6-4-16(5-7-18)23-26-13-19(27-23)22(24)29/h3-8,11,13,17,25,28H,9-10,12,14H2,1-2H3,(H2,24,29)(H,26,27)
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n/an/an/a 31n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against beta-1 adrenergic receptor measured by inhibition of positive chronotropic effect of isoproterenolin in isolated...


J Med Chem 29: 1065-80 (1986)


Article DOI: 10.1021/jm00156a028
BindingDB Entry DOI: 10.7270/Q2BP0408
More data for this
Ligand-Target Pair
Beta-1 adrenergic receptor


(GUINEA PIG)
BDBM50405417
PNG
(CHEMBL11155)
Show SMILES COc1ccc(CCNCC(O)COc2ccc(cc2)-c2nccs2)cc1OC
Show InChI InChI=1S/C22H26N2O4S/c1-26-20-8-3-16(13-21(20)27-2)9-10-23-14-18(25)15-28-19-6-4-17(5-7-19)22-24-11-12-29-22/h3-8,11-13,18,23,25H,9-10,14-15H2,1-2H3
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n/an/an/a 59n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against beta-1 adrenergic receptor measured by inhibition of positive chronotropic effect of isoproterenolin in isolated...


J Med Chem 29: 1065-80 (1986)


Article DOI: 10.1021/jm00156a028
BindingDB Entry DOI: 10.7270/Q2BP0408
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(GUINEA PIG)
BDBM50421760
PNG
(CHEMBL63421)
Show SMILES COc1ccc(CCNC[C@H](O)COc2ccc(cc2)-c2ncc([nH]2)C(C)=O)cc1OC
Show InChI InChI=1S/C24H29N3O5/c1-16(28)21-14-26-24(27-21)18-5-7-20(8-6-18)32-15-19(29)13-25-11-10-17-4-9-22(30-2)23(12-17)31-3/h4-9,12,14,19,25,29H,10-11,13,15H2,1-3H3,(H,26,27)/t19-/m0/s1
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n/an/an/a 6.31E+4n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against beta-2 adrenergic receptor was measured by the inhibition of isoproterenol-induced relaxation of PGF2-alpha cont...


J Med Chem 29: 1065-80 (1986)


Article DOI: 10.1021/jm00156a028
BindingDB Entry DOI: 10.7270/Q2BP0408
More data for this
Ligand-Target Pair
Beta-1 adrenergic receptor


(GUINEA PIG)
BDBM50405436
PNG
(CHEMBL11406)
Show SMILES CCOC(=O)c1cnc([nH]1)-c1ccc(OCC(O)CNCCc2ccc(OC)c(OC)c2)cc1
Show InChI InChI=1S/C25H31N3O6/c1-4-33-25(30)21-15-27-24(28-21)18-6-8-20(9-7-18)34-16-19(29)14-26-12-11-17-5-10-22(31-2)23(13-17)32-3/h5-10,13,15,19,26,29H,4,11-12,14,16H2,1-3H3,(H,27,28)
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n/an/an/a 6n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against beta-1 adrenergic receptor measured by inhibition of positive chronotropic effect of isoproterenolin in isolated...


J Med Chem 29: 1065-80 (1986)


Article DOI: 10.1021/jm00156a028
BindingDB Entry DOI: 10.7270/Q2BP0408
More data for this
Ligand-Target Pair
Beta-1 adrenergic receptor


(GUINEA PIG)
BDBM50405521
PNG
(ALO 1401-02 | ALO-1401-02 | BETAXOLOL HYDROCHLORID...)
Show SMILES CC(C)NCC(O)COc1ccc(CCOCC2CC2)cc1
Show InChI InChI=1S/C18H29NO3/c1-14(2)19-11-17(20)13-22-18-7-5-15(6-8-18)9-10-21-12-16-3-4-16/h5-8,14,16-17,19-20H,3-4,9-13H2,1-2H3
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n/an/an/a 1.70n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against beta-1 adrenergic receptor measured by inhibition of positive chronotropic effect of isoproterenolin in isolated...


J Med Chem 29: 1065-80 (1986)


Article DOI: 10.1021/jm00156a028
BindingDB Entry DOI: 10.7270/Q2BP0408
More data for this
Ligand-Target Pair
Beta-1 adrenergic receptor


(GUINEA PIG)
BDBM50405410
PNG
(CHEMBL11178)
Show SMILES COc1ccc(CCNCC(O)COc2ccc(cn2)-c2nc(c[nH]2)-c2cccs2)cc1OC
Show InChI InChI=1S/C25H28N4O4S/c1-31-21-7-5-17(12-22(21)32-2)9-10-26-14-19(30)16-33-24-8-6-18(13-27-24)25-28-15-20(29-25)23-4-3-11-34-23/h3-8,11-13,15,19,26,30H,9-10,14,16H2,1-2H3,(H,28,29)
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n/an/an/a 5.10n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against beta-1 adrenergic receptor measured by inhibition of positive chronotropic effect of isoproterenolin in isolated...


J Med Chem 29: 1065-80 (1986)


Article DOI: 10.1021/jm00156a028
BindingDB Entry DOI: 10.7270/Q2BP0408
More data for this
Ligand-Target Pair
Beta-1 adrenergic receptor


(GUINEA PIG)
BDBM50405404
PNG
(CHEMBL269219)
Show SMILES CC(C)NCC(O)COc1ccc(cc1)-c1ncc[nH]1
Show InChI InChI=1S/C15H21N3O2/c1-11(2)18-9-13(19)10-20-14-5-3-12(4-6-14)15-16-7-8-17-15/h3-8,11,13,18-19H,9-10H2,1-2H3,(H,16,17)
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n/an/an/a 23n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against beta-1 adrenergic receptor measured by inhibition of positive chronotropic effect of isoproterenolin in isolated...


J Med Chem 29: 1065-80 (1986)


Article DOI: 10.1021/jm00156a028
BindingDB Entry DOI: 10.7270/Q2BP0408
More data for this
Ligand-Target Pair
Beta-1 adrenergic receptor


(GUINEA PIG)
BDBM50405408
PNG
(CHEMBL2052004)
Show SMILES COCc1cnc([nH]1)-c1ccc(OC[C@@H](O)CNCCc2ccc(OC)c(OC)c2)cc1
Show InChI InChI=1S/C24H31N3O5/c1-29-15-19-13-26-24(27-19)18-5-7-21(8-6-18)32-16-20(28)14-25-11-10-17-4-9-22(30-2)23(12-17)31-3/h4-9,12-13,20,25,28H,10-11,14-16H2,1-3H3,(H,26,27)/t20-/m0/s1
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n/an/an/a 17n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against beta-1 adrenergic receptor measured by inhibition of positive chronotropic effect of isoproterenolin in isolated...


J Med Chem 29: 1065-80 (1986)


Article DOI: 10.1021/jm00156a028
BindingDB Entry DOI: 10.7270/Q2BP0408
More data for this
Ligand-Target Pair
Beta-1 adrenergic receptor


(GUINEA PIG)
BDBM50405433
PNG
(CHEMBL2052005)
Show SMILES CCOCCNC[C@H](O)COc1ccc(cc1)-c1nc(c[nH]1)-c1cccs1
Show InChI InChI=1S/C20H25N3O3S/c1-2-25-10-9-21-12-16(24)14-26-17-7-5-15(6-8-17)20-22-13-18(23-20)19-4-3-11-27-19/h3-8,11,13,16,21,24H,2,9-10,12,14H2,1H3,(H,22,23)/t16-/m0/s1
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n/an/an/a 6.5n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against beta-1 adrenergic receptor measured by inhibition of positive chronotropic effect of isoproterenolin in isolated...


J Med Chem 29: 1065-80 (1986)


Article DOI: 10.1021/jm00156a028
BindingDB Entry DOI: 10.7270/Q2BP0408
More data for this
Ligand-Target Pair
Beta-1 adrenergic receptor


(GUINEA PIG)
BDBM50405424
PNG
(CHEMBL2052006)
Show SMILES COc1ccc(CCNC[C@H](O)COc2ccc(cc2)-c2nc(c[nH]2)C(C)(C)C)cc1OC
Show InChI InChI=1S/C26H35N3O4/c1-26(2,3)24-16-28-25(29-24)19-7-9-21(10-8-19)33-17-20(30)15-27-13-12-18-6-11-22(31-4)23(14-18)32-5/h6-11,14,16,20,27,30H,12-13,15,17H2,1-5H3,(H,28,29)/t20-/m0/s1
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n/an/an/a 20n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against beta-1 adrenergic receptor measured by inhibition of positive chronotropic effect of isoproterenolin in isolated...


J Med Chem 29: 1065-80 (1986)


Article DOI: 10.1021/jm00156a028
BindingDB Entry DOI: 10.7270/Q2BP0408
More data for this
Ligand-Target Pair
Beta-1 adrenergic receptor


(GUINEA PIG)
BDBM50405419
PNG
(CHEMBL10983)
Show SMILES COc1ccc(CCNCC(O)COc2ccc(cc2)-c2nc(C)c(C)[nH]2)cc1OC
Show InChI InChI=1S/C24H31N3O4/c1-16-17(2)27-24(26-16)19-6-8-21(9-7-19)31-15-20(28)14-25-12-11-18-5-10-22(29-3)23(13-18)30-4/h5-10,13,20,25,28H,11-12,14-15H2,1-4H3,(H,26,27)
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n/an/an/a 15n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against beta-1 adrenergic receptor measured by inhibition of positive chronotropic effect of isoproterenolin in isolated...


J Med Chem 29: 1065-80 (1986)


Article DOI: 10.1021/jm00156a028
BindingDB Entry DOI: 10.7270/Q2BP0408
More data for this
Ligand-Target Pair
Beta-1 adrenergic receptor


(GUINEA PIG)
BDBM50404977
PNG
(CHEMBL11671)
Show SMILES COc1ccc(CCNCC(O)COc2ccc(cc2)-c2nc(c[nH]2)-c2cccs2)cc1OC
Show InChI InChI=1S/C26H29N3O4S/c1-31-23-10-5-18(14-24(23)32-2)11-12-27-15-20(30)17-33-21-8-6-19(7-9-21)26-28-16-22(29-26)25-4-3-13-34-25/h3-10,13-14,16,20,27,30H,11-12,15,17H2,1-2H3,(H,28,29)
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n/an/an/a 0.851n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against beta-1 adrenergic receptor measured by inhibition of positive chronotropic effect of isoproterenolin in isolated...


J Med Chem 29: 1065-80 (1986)


Article DOI: 10.1021/jm00156a028
BindingDB Entry DOI: 10.7270/Q2BP0408
More data for this
Ligand-Target Pair
Beta-1 adrenergic receptor


(GUINEA PIG)
BDBM50405403
PNG
(CHEMBL11125)
Show SMILES CC(C)NCC(O)COc1ccc(Cc2ncc(Br)[nH]2)cc1
Show InChI InChI=1S/C16H22BrN3O2/c1-11(2)18-8-13(21)10-22-14-5-3-12(4-6-14)7-16-19-9-15(17)20-16/h3-6,9,11,13,18,21H,7-8,10H2,1-2H3,(H,19,20)
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n/an/an/a 3.20n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against beta-1 adrenergic receptor was measured by the inhibition of the positive chronotropic effectof isoproterenolin ...


J Med Chem 29: 1065-80 (1986)


Article DOI: 10.1021/jm00156a028
BindingDB Entry DOI: 10.7270/Q2BP0408
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(GUINEA PIG)
BDBM50405433
PNG
(CHEMBL2052005)
Show SMILES CCOCCNC[C@H](O)COc1ccc(cc1)-c1nc(c[nH]1)-c1cccs1
Show InChI InChI=1S/C20H25N3O3S/c1-2-25-10-9-21-12-16(24)14-26-17-7-5-15(6-8-17)20-22-13-18(23-20)19-4-3-11-27-19/h3-8,11,13,16,21,24H,2,9-10,12,14H2,1H3,(H,22,23)/t16-/m0/s1
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n/an/an/a 5.62E+3n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against beta-2 adrenergic receptor was measured by the inhibition of isoproterenol-induced relaxation of PGF2-alpha cont...


J Med Chem 29: 1065-80 (1986)


Article DOI: 10.1021/jm00156a028
BindingDB Entry DOI: 10.7270/Q2BP0408
More data for this
Ligand-Target Pair
Beta-1 adrenergic receptor


(GUINEA PIG)
BDBM50405413
PNG
(CHEMBL11112)
Show SMILES COc1ccc(CCNCC(O)COc2ccc(CCc3ncc(Br)[nH]3)cc2)cc1OC
Show InChI InChI=1S/C24H30BrN3O4/c1-30-21-9-5-18(13-22(21)31-2)11-12-26-14-19(29)16-32-20-7-3-17(4-8-20)6-10-24-27-15-23(25)28-24/h3-5,7-9,13,15,19,26,29H,6,10-12,14,16H2,1-2H3,(H,27,28)
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n/an/an/a 1.15E+3n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against beta-2 adrenergic receptor was measured by the inhibition of isoproterenol-induced relaxation of PGF2-alpha cont...


J Med Chem 29: 1065-80 (1986)


Article DOI: 10.1021/jm00156a028
BindingDB Entry DOI: 10.7270/Q2BP0408
More data for this
Ligand-Target Pair
Beta-1 adrenergic receptor


(GUINEA PIG)
BDBM50405409
PNG
(CHEMBL11092)
Show SMILES COc1ccc(CCNCC(O)COc2ccc(cc2Cl)-c2ncc(Br)[nH]2)cc1OC
Show InChI InChI=1S/C22H25BrClN3O4/c1-29-19-5-3-14(9-20(19)30-2)7-8-25-11-16(28)13-31-18-6-4-15(10-17(18)24)22-26-12-21(23)27-22/h3-6,9-10,12,16,25,28H,7-8,11,13H2,1-2H3,(H,26,27)
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n/an/an/a 7.60n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against beta-1 adrenergic receptor measured by inhibition of positive chronotropic effect of isoproterenolin in isolated...


J Med Chem 29: 1065-80 (1986)


Article DOI: 10.1021/jm00156a028
BindingDB Entry DOI: 10.7270/Q2BP0408
More data for this
Ligand-Target Pair
Beta-1 adrenergic receptor


(GUINEA PIG)
BDBM50405418
PNG
(CHEMBL11093)
Show SMILES CCOCc1cnc([nH]1)-c1ccc(OCC(O)CNCCc2ccc(OC)c(OC)c2)cc1
Show InChI InChI=1S/C25H33N3O5/c1-4-32-16-20-14-27-25(28-20)19-6-8-22(9-7-19)33-17-21(29)15-26-12-11-18-5-10-23(30-2)24(13-18)31-3/h5-10,13-14,21,26,29H,4,11-12,15-17H2,1-3H3,(H,27,28)
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n/an/an/a 13n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against beta-1 adrenergic receptor measured by inhibition of positive chronotropic effect of isoproterenolin in isolated...


J Med Chem 29: 1065-80 (1986)


Article DOI: 10.1021/jm00156a028
BindingDB Entry DOI: 10.7270/Q2BP0408
More data for this
Ligand-Target Pair
Beta-1 adrenergic receptor


(GUINEA PIG)
BDBM50405406
PNG
(CHEMBL274830)
Show SMILES CCCNCC(O)COc1ccc(cc1)-c1nc(c[nH]1)-c1cccs1
Show InChI InChI=1S/C19H23N3O2S/c1-2-9-20-11-15(23)13-24-16-7-5-14(6-8-16)19-21-12-17(22-19)18-4-3-10-25-18/h3-8,10,12,15,20,23H,2,9,11,13H2,1H3,(H,21,22)
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n/an/an/a 16n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against beta-1 adrenergic receptor measured by inhibition of positive chronotropic effect of isoproterenolin in isolated...


J Med Chem 29: 1065-80 (1986)


Article DOI: 10.1021/jm00156a028
BindingDB Entry DOI: 10.7270/Q2BP0408
More data for this
Ligand-Target Pair
Beta-1 adrenergic receptor


(GUINEA PIG)
BDBM50404988
PNG
(CHEMBL11171)
Show SMILES CC(C)NCC(O)COc1ccc(cc1)-c1nc(c[nH]1)-c1cccs1
Show InChI InChI=1S/C19H23N3O2S/c1-13(2)20-10-15(23)12-24-16-7-5-14(6-8-16)19-21-11-17(22-19)18-4-3-9-25-18/h3-9,11,13,15,20,23H,10,12H2,1-2H3,(H,21,22)
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n/an/an/a 1.20n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against beta-1 adrenergic receptor measured by inhibition of positive chronotropic effect of isoproterenolin in isolated...


J Med Chem 29: 1065-80 (1986)


Article DOI: 10.1021/jm00156a028
BindingDB Entry DOI: 10.7270/Q2BP0408
More data for this
Ligand-Target Pair
Beta-1 adrenergic receptor


(GUINEA PIG)
BDBM50405405
PNG
(CHEMBL11097)
Show SMILES COc1ccc(CCNCC(O)COc2ccc(cc2)-c2nc(c[nH]2)C(C)(C)C)cc1OC
Show InChI InChI=1S/C26H35N3O4/c1-26(2,3)24-16-28-25(29-24)19-7-9-21(10-8-19)33-17-20(30)15-27-13-12-18-6-11-22(31-4)23(14-18)32-5/h6-11,14,16,20,27,30H,12-13,15,17H2,1-5H3,(H,28,29)
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n/an/an/a 22n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against beta-1 adrenergic receptor measured by inhibition of positive chronotropic effect of isoproterenolin in isolated...


J Med Chem 29: 1065-80 (1986)


Article DOI: 10.1021/jm00156a028
BindingDB Entry DOI: 10.7270/Q2BP0408
More data for this
Ligand-Target Pair
Beta-1 adrenergic receptor


(GUINEA PIG)
BDBM50405411
PNG
(CHEMBL11431)
Show SMILES COc1ccc(CCNCC(O)COc2ccc(cc2Cl)-c2nc(c[nH]2)-c2cccs2)cc1OC
Show InChI InChI=1S/C26H28ClN3O4S/c1-32-23-7-5-17(12-24(23)33-2)9-10-28-14-19(31)16-34-22-8-6-18(13-20(22)27)26-29-15-21(30-26)25-4-3-11-35-25/h3-8,11-13,15,19,28,31H,9-10,14,16H2,1-2H3,(H,29,30)
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n/an/an/a 5n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against beta-1 adrenergic receptor measured by inhibition of positive chronotropic effect of isoproterenolin in isolated...


J Med Chem 29: 1065-80 (1986)


Article DOI: 10.1021/jm00156a028
BindingDB Entry DOI: 10.7270/Q2BP0408
More data for this
Ligand-Target Pair
Beta-1 adrenergic receptor


(GUINEA PIG)
BDBM50405416
PNG
(CHEMBL11051)
Show SMILES COc1ccc(CCNCC(O)COc2ccc(cc2)-c2ncc(Br)[nH]2)cc1OC
Show InChI InChI=1S/C22H26BrN3O4/c1-28-19-8-3-15(11-20(19)29-2)9-10-24-12-17(27)14-30-18-6-4-16(5-7-18)22-25-13-21(23)26-22/h3-8,11,13,17,24,27H,9-10,12,14H2,1-2H3,(H,25,26)
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n/an/an/a 2n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against beta-1 adrenergic receptor measured by inhibition of positive chronotropic effect of isoproterenolin in isolated...


J Med Chem 29: 1065-80 (1986)


Article DOI: 10.1021/jm00156a028
BindingDB Entry DOI: 10.7270/Q2BP0408
More data for this
Ligand-Target Pair
Beta-1 adrenergic receptor


(GUINEA PIG)
BDBM50405445
PNG
(CHEMBL10814)
Show SMILES COc1ccc(CCNCC(O)COc2ccc(cc2)-c2ncc(CO)[nH]2)cc1OC
Show InChI InChI=1S/C23H29N3O5/c1-29-21-8-3-16(11-22(21)30-2)9-10-24-13-19(28)15-31-20-6-4-17(5-7-20)23-25-12-18(14-27)26-23/h3-8,11-12,19,24,27-28H,9-10,13-15H2,1-2H3,(H,25,26)
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n/an/an/a>316n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against beta-1 adrenergic receptor measured by inhibition of positive chronotropic effect of isoproterenolin in isolated...


J Med Chem 29: 1065-80 (1986)


Article DOI: 10.1021/jm00156a028
BindingDB Entry DOI: 10.7270/Q2BP0408
More data for this
Ligand-Target Pair
Beta-1 adrenergic receptor


(GUINEA PIG)
BDBM50405444
PNG
(CHEMBL10813)
Show SMILES COc1ccc(CCNCC(O)COc2ccc(cc2)-c2nc(C)c([nH]2)C(C)=O)cc1OC
Show InChI InChI=1S/C25H31N3O5/c1-16-24(17(2)29)28-25(27-16)19-6-8-21(9-7-19)33-15-20(30)14-26-12-11-18-5-10-22(31-3)23(13-18)32-4/h5-10,13,20,26,30H,11-12,14-15H2,1-4H3,(H,27,28)
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n/an/an/a 11n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against beta-1 adrenergic receptor measured by inhibition of positive chronotropic effect of isoproterenolin in isolated...


J Med Chem 29: 1065-80 (1986)


Article DOI: 10.1021/jm00156a028
BindingDB Entry DOI: 10.7270/Q2BP0408
More data for this
Ligand-Target Pair
Beta-1 adrenergic receptor


(GUINEA PIG)
BDBM50405439
PNG
(CHEMBL11414)
Show SMILES COCc1[nH]c(nc1C)-c1ccc(OCC(O)CNCCc2ccc(OC)c(OC)c2)cc1
Show InChI InChI=1S/C25H33N3O5/c1-17-22(16-30-2)28-25(27-17)19-6-8-21(9-7-19)33-15-20(29)14-26-12-11-18-5-10-23(31-3)24(13-18)32-4/h5-10,13,20,26,29H,11-12,14-16H2,1-4H3,(H,27,28)
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n/an/an/a 25n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against beta-1 adrenergic receptor measured by inhibition of positive chronotropic effect of isoproterenolin in isolated...


J Med Chem 29: 1065-80 (1986)


Article DOI: 10.1021/jm00156a028
BindingDB Entry DOI: 10.7270/Q2BP0408
More data for this
Ligand-Target Pair
Beta-1 adrenergic receptor


(GUINEA PIG)
BDBM50405443
PNG
(CHEMBL10879)
Show SMILES COc1ccc(CCNCC(O)COc2ccc(cc2Br)-c2nc(C)c[nH]2)cc1OC
Show InChI InChI=1S/C23H28BrN3O4/c1-15-12-26-23(27-15)17-5-7-20(19(24)11-17)31-14-18(28)13-25-9-8-16-4-6-21(29-2)22(10-16)30-3/h4-7,10-12,18,25,28H,8-9,13-14H2,1-3H3,(H,26,27)
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n/an/an/a 50n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against beta-1 adrenergic receptor measured by inhibition of positive chronotropic effect of isoproterenolin in isolated...


J Med Chem 29: 1065-80 (1986)


Article DOI: 10.1021/jm00156a028
BindingDB Entry DOI: 10.7270/Q2BP0408
More data for this
Ligand-Target Pair
Beta-1 adrenergic receptor


(GUINEA PIG)
BDBM50405427
PNG
(CHEMBL11307)
Show SMILES COc1ccc(CCNCC(O)COc2ccc(cc2)-c2nc(C)c(Br)[nH]2)cc1OC
Show InChI InChI=1S/C23H28BrN3O4/c1-15-22(24)27-23(26-15)17-5-7-19(8-6-17)31-14-18(28)13-25-11-10-16-4-9-20(29-2)21(12-16)30-3/h4-9,12,18,25,28H,10-11,13-14H2,1-3H3,(H,26,27)
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n/an/an/a 31n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against beta-1 adrenergic receptor was measured by the inhibition of isoproterenol-induced relaxation of PGF2-alpha cont...


J Med Chem 29: 1065-80 (1986)


Article DOI: 10.1021/jm00156a028
BindingDB Entry DOI: 10.7270/Q2BP0408
More data for this
Ligand-Target Pair
Beta-1 adrenergic receptor


(GUINEA PIG)
BDBM50405413
PNG
(CHEMBL11112)
Show SMILES COc1ccc(CCNCC(O)COc2ccc(CCc3ncc(Br)[nH]3)cc2)cc1OC
Show InChI InChI=1S/C24H30BrN3O4/c1-30-21-9-5-18(13-22(21)31-2)11-12-26-14-19(29)16-32-20-7-3-17(4-8-20)6-10-24-27-15-23(25)28-24/h3-5,7-9,13,15,19,26,29H,6,10-12,14,16H2,1-2H3,(H,27,28)
UniProtKB/TrEMBL

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n/an/an/a 2.90n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against beta-1 adrenergic receptor measured by inhibition of positive chronotropic effect of isoproterenolin in isolated...


J Med Chem 29: 1065-80 (1986)


Article DOI: 10.1021/jm00156a028
BindingDB Entry DOI: 10.7270/Q2BP0408
More data for this
Ligand-Target Pair
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