Compile Data Set for Download or QSAR
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Found 40 Enz. Inhib. hit(s) with all data for entry = 50006857
Target5-hydroxytryptamine receptor 1A(Mus musculus (Mouse))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50054718(3-Amino-thiophene-2-carboxylic acid [4-(4-benzo[d]...)
Affinity DataIC50:  1.30nMAssay Description:Inhibitory activity against serotonin 5-hydroxytryptamine 1A receptor from mice.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Mus musculus (Mouse))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50054710(1,2,3,4-Tetrahydro-quinoline-8-carboxylic acid [4-...)
Affinity DataIC50:  1.90nMAssay Description:Inhibitory activity against serotonin 5-hydroxytryptamine 1A receptor from mice.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Mus musculus (Mouse))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50054713(2-Amino-thiophene-3-carboxylic acid [4-(4-benzo[d]...)
Affinity DataIC50:  2nMAssay Description:Inhibitory activity against serotonin 5-hydroxytryptamine 1A receptor from mice.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Mus musculus (Mouse))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50054716(1H-Indazole-3-carboxylic acid [4-(4-benzo[d]isothi...)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of mouse Dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Mus musculus (Mouse))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50054706(1H-Indole-7-carboxylic acid [4-(4-benzo[d]isothiaz...)
Affinity DataIC50:  2.70nMAssay Description:Inhibitory activity against serotonin 5-hydroxytryptamine 1A receptor from mice.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Mus musculus (Mouse))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50054707(CHEMBL344994 | Pyridine-2-carboxylic acid [4-(4-be...)
Affinity DataIC50:  2.80nMAssay Description:Inhibitory activity against serotonin 5-hydroxytryptamine 1A receptor from mice.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Mus musculus (Mouse))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50054705(2-Amino-N-[4-(4-benzo[d]isothiazol-3-yl-piperazin-...)
Affinity DataIC50:  3.30nMAssay Description:Inhibitory activity against serotonin 5-hydroxytryptamine 1A receptor from mice.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Mus musculus (Mouse))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50054715(4-Amino-thiophene-3-carboxylic acid [4-(4-benzo[d]...)
Affinity DataIC50:  3.5nMAssay Description:Inhibitory activity against serotonin 5-hydroxytryptamine 1A receptor from mice.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Mus musculus (Mouse))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50054716(1H-Indazole-3-carboxylic acid [4-(4-benzo[d]isothi...)
Affinity DataIC50:  3.60nMAssay Description:Inhibitory activity against serotonin 5-hydroxytryptamine 1A receptor from mice.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Mus musculus (Mouse))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50054714(3-Amino-pyridine-2-carboxylic acid [4-(4-benzo[d]i...)
Affinity DataIC50:  3.80nMAssay Description:Inhibitory activity against serotonin 5-hydroxytryptamine 1A receptor from mice.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Mus musculus (Mouse))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50054712(3H-Benzoimidazole-4-carboxylic acid [4-(4-benzo[d]...)
Affinity DataIC50:  4.20nMAssay Description:Inhibitory activity against serotonin 5-hydroxytryptamine 1A receptor from mice.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Mus musculus (Mouse))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50054704(2,3-Dihydro-1H-indole-7-carboxylic acid [4-(4-benz...)
Affinity DataIC50:  4.30nMAssay Description:Inhibitory activity against serotonin 5-hydroxytryptamine 1A receptor from mice.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Mus musculus (Mouse))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50054703(CHEMBL358268 | Quinoline-8-carboxylic acid [4-(4-b...)
Affinity DataIC50:  4.30nMAssay Description:Inhibitory activity against serotonin 5-hydroxytryptamine 1A receptor from mice.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Mus musculus (Mouse))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50054711(4-Amino-N-[4-(4-benzo[d]isothiazol-3-yl-piperazin-...)
Affinity DataIC50:  4.70nMAssay Description:Inhibitory activity against Dopamine receptor D2 from miceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Mus musculus (Mouse))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50054719(CHEMBL356498 | N-[4-(4-Benzo[d]isothiazol-3-yl-pip...)
Affinity DataIC50:  4.90nMAssay Description:Inhibitory activity against serotonin 5-hydroxytryptamine 1A receptor from mice.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Mus musculus (Mouse))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50054711(4-Amino-N-[4-(4-benzo[d]isothiazol-3-yl-piperazin-...)
Affinity DataIC50:  5.10nMAssay Description:Inhibitory activity against serotonin 5-hydroxytryptamine 1A receptor from mice.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Mus musculus (Mouse))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50054708(1H-Indole-3-carboxylic acid [4-(4-benzo[d]isothiaz...)
Affinity DataIC50:  5.80nMAssay Description:Inhibitory activity against serotonin 5-hydroxytryptamine 1A receptor from mice.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Mus musculus (Mouse))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50054702(3-Amino-benzo[b]thiophene-2-carboxylic acid [4-(4-...)
Affinity DataIC50:  5.80nMAssay Description:Inhibition of mouse Dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Mus musculus (Mouse))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50054702(3-Amino-benzo[b]thiophene-2-carboxylic acid [4-(4-...)
Affinity DataIC50:  5.80nMAssay Description:Inhibitory activity against serotonin 5-hydroxytryptamine 1A receptor from mice.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Mus musculus (Mouse))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50054715(4-Amino-thiophene-3-carboxylic acid [4-(4-benzo[d]...)
Affinity DataIC50:  6nMAssay Description:Inhibition of mouse Dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Mus musculus (Mouse))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50054709(CHEMBL141494 | N-[4-(4-Benzo[d]isothiazol-3-yl-pip...)
Affinity DataIC50:  6.60nMAssay Description:Inhibitory activity against serotonin 5-hydroxytryptamine 1A receptor from mice.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Mus musculus (Mouse))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50054717(3-Amino-N-[4-(4-benzo[d]isothiazol-3-yl-piperazin-...)
Affinity DataIC50:  7nMAssay Description:Inhibitory activity against serotonin 5-hydroxytryptamine 1A receptor from mice.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Mus musculus (Mouse))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50054712(3H-Benzoimidazole-4-carboxylic acid [4-(4-benzo[d]...)
Affinity DataIC50:  7.60nMAssay Description:Inhibitory activity against Dopamine receptor D2 from miceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Mus musculus (Mouse))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50054705(2-Amino-N-[4-(4-benzo[d]isothiazol-3-yl-piperazin-...)
Affinity DataIC50:  7.80nMAssay Description:Inhibition of mouse Dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Mus musculus (Mouse))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50054718(3-Amino-thiophene-2-carboxylic acid [4-(4-benzo[d]...)
Affinity DataIC50:  9.60nMAssay Description:Inhibition of mouse Dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Mus musculus (Mouse))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50054713(2-Amino-thiophene-3-carboxylic acid [4-(4-benzo[d]...)
Affinity DataIC50:  11nMAssay Description:Inhibitory activity against Dopamine receptor D2 from miceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Mus musculus (Mouse))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50054708(1H-Indole-3-carboxylic acid [4-(4-benzo[d]isothiaz...)
Affinity DataIC50:  14nMAssay Description:Inhibitory activity against Dopamine receptor D2 from miceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Mus musculus (Mouse))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50054703(CHEMBL358268 | Quinoline-8-carboxylic acid [4-(4-b...)
Affinity DataIC50:  14nMAssay Description:Inhibitory activity against Dopamine receptor D2 from miceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Mus musculus (Mouse))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50054717(3-Amino-N-[4-(4-benzo[d]isothiazol-3-yl-piperazin-...)
Affinity DataIC50:  16nMAssay Description:Inhibitory activity against Dopamine receptor D2 from miceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Mus musculus (Mouse))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50001885((risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-...)
Affinity DataIC50:  23nMAssay Description:Inhibition of mouse Dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Mus musculus (Mouse))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50054707(CHEMBL344994 | Pyridine-2-carboxylic acid [4-(4-be...)
Affinity DataIC50:  24nMAssay Description:Inhibition of mouse Dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Mus musculus (Mouse))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50054714(3-Amino-pyridine-2-carboxylic acid [4-(4-benzo[d]i...)
Affinity DataIC50:  24nMAssay Description:Inhibitory activity against Dopamine receptor D2 from miceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Mus musculus (Mouse))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50054709(CHEMBL141494 | N-[4-(4-Benzo[d]isothiazol-3-yl-pip...)
Affinity DataIC50:  25nMAssay Description:Inhibitory activity against Dopamine receptor D2 from miceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Mus musculus (Mouse))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50054706(1H-Indole-7-carboxylic acid [4-(4-benzo[d]isothiaz...)
Affinity DataIC50:  28nMAssay Description:Inhibition of mouse Dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Mus musculus (Mouse))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50054710(1,2,3,4-Tetrahydro-quinoline-8-carboxylic acid [4-...)
Affinity DataIC50:  28nMAssay Description:Inhibition of mouse Dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Mus musculus (Mouse))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50054704(2,3-Dihydro-1H-indole-7-carboxylic acid [4-(4-benz...)
Affinity DataIC50:  34nMAssay Description:Inhibition of mouse Dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Mus musculus (Mouse))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50054719(CHEMBL356498 | N-[4-(4-Benzo[d]isothiazol-3-yl-pip...)
Affinity DataIC50:  47nMAssay Description:Inhibition of mouse Dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Mus musculus (Mouse))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50001884(2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl...)
Affinity DataIC50:  290nMAssay Description:Inhibition of mouse Dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Mus musculus (Mouse))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50001885((risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-...)
Affinity DataIC50:  430nMAssay Description:Inhibitory activity against serotonin 5-hydroxytryptamine 1A receptor from mice.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Mus musculus (Mouse))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50001884(2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibitory activity against serotonin 5-hydroxytryptamine 1A receptor from mice.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed