Found 31 Enz. Inhib. hit(s) with all data for entry = 50044462 TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
University Of Alabama At Birmingham
Curated by ChEMBL
University Of Alabama At Birmingham
Curated by ChEMBL
Affinity DataKd: 1.55E+3nMAssay Description:Agonist activity at human RXR-alpha-ligand binding domain homodimers assessed as coactivator recruitment by measuring GRIP1 binding to receptor by is...More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+3nMAssay Description:Agonist activity at RXR-alpha in rat R3KE cells infected with oncogene KLF4-ER assessed as inhibition of KLF4-mediated oncogenic transformationMore data for this Ligand-Target Pair
3D Structure (crystal)TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
University Of Alabama At Birmingham
Curated by ChEMBL
University Of Alabama At Birmingham
Curated by ChEMBL
Affinity DataKd: 1.75E+3nMAssay Description:Agonist activity at human RXR-alpha-ligand binding domain homodimers assessed as coactivator recruitment by measuring GRIP1 binding to receptor by is...More data for this Ligand-Target Pair
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
University Of Alabama At Birmingham
Curated by ChEMBL
University Of Alabama At Birmingham
Curated by ChEMBL
Affinity DataKd: 1.86E+3nMAssay Description:Agonist activity at human RXR-alpha-ligand binding domain homodimers assessed as coactivator recruitment by measuring GRIP1 binding to receptor by is...More data for this Ligand-Target Pair
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
University Of Alabama At Birmingham
Curated by ChEMBL
University Of Alabama At Birmingham
Curated by ChEMBL
Affinity DataKd: 1.88E+3nMAssay Description:Agonist activity at human RXR-alpha-ligand binding domain homodimers assessed as coactivator recruitment by measuring GRIP1 binding to receptor by is...More data for this Ligand-Target Pair
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
University Of Alabama At Birmingham
Curated by ChEMBL
University Of Alabama At Birmingham
Curated by ChEMBL
Affinity DataKd: 1.89E+3nMAssay Description:Agonist activity at human RXR-alpha-ligand binding domain homodimers assessed as coactivator recruitment by measuring GRIP1 binding to receptor by is...More data for this Ligand-Target Pair
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
University Of Alabama At Birmingham
Curated by ChEMBL
University Of Alabama At Birmingham
Curated by ChEMBL
Affinity DataKd: 2.24E+3nMAssay Description:Agonist activity at human RXR-alpha-ligand binding domain homodimers assessed as coactivator recruitment by measuring GRIP1 binding to receptor by is...More data for this Ligand-Target Pair
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
University Of Alabama At Birmingham
Curated by ChEMBL
University Of Alabama At Birmingham
Curated by ChEMBL
Affinity DataKd: 2.33E+3nMAssay Description:Agonist activity at human RXR-alpha-ligand binding domain homodimers assessed as coactivator recruitment by measuring GRIP1 binding to receptor by is...More data for this Ligand-Target Pair
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
University Of Alabama At Birmingham
Curated by ChEMBL
University Of Alabama At Birmingham
Curated by ChEMBL
Affinity DataKd: 8nMAssay Description:Binding affinity to human RXR-alpha-ligand binding domain homodimers by fluorescence quenching methodMore data for this Ligand-Target Pair
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
University Of Alabama At Birmingham
Curated by ChEMBL
University Of Alabama At Birmingham
Curated by ChEMBL
Affinity DataKd: 10nMAssay Description:Binding affinity to human RXR-alpha-ligand binding domain homodimers by fluorescence quenching methodMore data for this Ligand-Target Pair
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
University Of Alabama At Birmingham
Curated by ChEMBL
University Of Alabama At Birmingham
Curated by ChEMBL
Affinity DataKd: 14nMAssay Description:Binding affinity to human RXR-alpha-ligand binding domain homodimers by fluorescence quenching methodMore data for this Ligand-Target Pair
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
University Of Alabama At Birmingham
Curated by ChEMBL
University Of Alabama At Birmingham
Curated by ChEMBL
Affinity DataKd: 15nMAssay Description:Binding affinity to human RXR-alpha-ligand binding domain homodimers by fluorescence quenching methodMore data for this Ligand-Target Pair
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
University Of Alabama At Birmingham
Curated by ChEMBL
University Of Alabama At Birmingham
Curated by ChEMBL
Affinity DataKd: 18nMAssay Description:Binding affinity to human RXR-alpha-ligand binding domain homodimers by fluorescence quenching methodMore data for this Ligand-Target Pair
Affinity DataEC50: 19nMAssay Description:Agonist activity at RXR-alpha in rat R3KE cells infected with oncogene KLF4-ER assessed as inhibition of KLF4-mediated oncogenic transformationMore data for this Ligand-Target Pair
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
University Of Alabama At Birmingham
Curated by ChEMBL
University Of Alabama At Birmingham
Curated by ChEMBL
Affinity DataKd: 25nMAssay Description:Binding affinity to human RXR-alpha-ligand binding domain homodimers by fluorescence quenching methodMore data for this Ligand-Target Pair
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
University Of Alabama At Birmingham
Curated by ChEMBL
University Of Alabama At Birmingham
Curated by ChEMBL
Affinity DataKd: 26nMAssay Description:Binding affinity to human RXR-alpha-ligand binding domain homodimers by fluorescence quenching methodMore data for this Ligand-Target Pair
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
University Of Alabama At Birmingham
Curated by ChEMBL
University Of Alabama At Birmingham
Curated by ChEMBL
Affinity DataKd: 33nMAssay Description:Binding affinity to human RXR-alpha-ligand binding domain homodimers by fluorescence quenching methodMore data for this Ligand-Target Pair
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
University Of Alabama At Birmingham
Curated by ChEMBL
University Of Alabama At Birmingham
Curated by ChEMBL
Affinity DataEC50: 40nMAssay Description:Agonist activity at Gal4-fused human RXR-alpha expressed in HEK293 cells assessed as receptor-mediated transcriptional activity treated 24 hrs after ...More data for this Ligand-Target Pair
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
University Of Alabama At Birmingham
Curated by ChEMBL
University Of Alabama At Birmingham
Curated by ChEMBL
Affinity DataEC50: 100nMAssay Description:Agonist activity at Gal4-fused human RXR-alpha expressed in HEK293 cells assessed as receptor-mediated transcriptional activity treated 24 hrs after ...More data for this Ligand-Target Pair
Affinity DataEC50: 110nMAssay Description:Agonist activity at RXR-alpha in rat R3KE cells infected with oncogene KLF4-ER assessed as inhibition of KLF4-mediated oncogenic transformationMore data for this Ligand-Target Pair
Affinity DataEC50: 110nMAssay Description:Agonist activity at RXR-alpha in rat R3KE cells infected with oncogene KLF4-ER assessed as inhibition of KLF4-mediated oncogenic transformationMore data for this Ligand-Target Pair
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
University Of Alabama At Birmingham
Curated by ChEMBL
University Of Alabama At Birmingham
Curated by ChEMBL
Affinity DataEC50: 120nMAssay Description:Agonist activity at Gal4-fused human RXR-alpha expressed in HEK293 cells assessed as receptor-mediated transcriptional activity treated 24 hrs after ...More data for this Ligand-Target Pair
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
University Of Alabama At Birmingham
Curated by ChEMBL
University Of Alabama At Birmingham
Curated by ChEMBL
Affinity DataEC50: 120nMAssay Description:Agonist activity at Gal4-fused human RXR-alpha expressed in HEK293 cells assessed as receptor-mediated transcriptional activity treated 24 hrs after ...More data for this Ligand-Target Pair
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
University Of Alabama At Birmingham
Curated by ChEMBL
University Of Alabama At Birmingham
Curated by ChEMBL
Affinity DataEC50: 160nMAssay Description:Agonist activity at Gal4-fused human RXR-alpha expressed in HEK293 cells assessed as receptor-mediated transcriptional activity treated 24 hrs after ...More data for this Ligand-Target Pair
Affinity DataEC50: 400nMAssay Description:Agonist activity at RXR-alpha in rat R3KE cells infected with oncogene KLF4-ER assessed as inhibition of KLF4-mediated oncogenic transformationMore data for this Ligand-Target Pair
Affinity DataEC50: 440nMAssay Description:Agonist activity at RXR-alpha in rat R3KE cells infected with oncogene KLF4-ER assessed as inhibition of KLF4-mediated oncogenic transformationMore data for this Ligand-Target Pair
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
University Of Alabama At Birmingham
Curated by ChEMBL
University Of Alabama At Birmingham
Curated by ChEMBL
Affinity DataEC50: 620nMAssay Description:Agonist activity at Gal4-fused human RXR-alpha expressed in HEK293 cells assessed as receptor-mediated transcriptional activity treated 24 hrs after ...More data for this Ligand-Target Pair
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
University Of Alabama At Birmingham
Curated by ChEMBL
University Of Alabama At Birmingham
Curated by ChEMBL
Affinity DataEC50: 720nMAssay Description:Agonist activity at Gal4-fused human RXR-alpha expressed in HEK293 cells assessed as receptor-mediated transcriptional activity treated 24 hrs after ...More data for this Ligand-Target Pair
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
University Of Alabama At Birmingham
Curated by ChEMBL
University Of Alabama At Birmingham
Curated by ChEMBL
Affinity DataEC50: 820nMAssay Description:Agonist activity at Gal4-fused human RXR-alpha expressed in HEK293 cells assessed as receptor-mediated transcriptional activity treated 24 hrs after ...More data for this Ligand-Target Pair
Affinity DataEC50: 880nMAssay Description:Agonist activity at RXR-alpha in rat R3KE cells infected with oncogene KLF4-ER assessed as inhibition of KLF4-mediated oncogenic transformationMore data for this Ligand-Target Pair
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
University Of Alabama At Birmingham
Curated by ChEMBL
University Of Alabama At Birmingham
Curated by ChEMBL
Affinity DataKd: 1.56E+3nMAssay Description:Agonist activity at human RXR-alpha-ligand binding domain homodimers assessed as coactivator recruitment by measuring GRIP1 binding to receptor by is...More data for this Ligand-Target Pair
