Compile Data Set for Download or QSAR
maximum 50k data
Found 36 Enz. Inhib. hit(s) with all data for entry = 50009664
TargetKappa-type opioid receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50086359(CHEMBL147191 | N-Cyclohexylmethyl-2,2-dimethyl-3-m...)
Affinity DataKi:  1.20nMAssay Description:Inhibition of [3H]U-69,593 binding to human Opioid receptor kappa 1 expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50000788((morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-az...)
Affinity DataKi:  1.20nMAssay Description:Inhibition of [3H]U-69,593 binding to human Opioid receptor kappa 1 expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetKappa-type opioid receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50086361(3-(3-Hydroxy-phenyl)-2,2-dimethyl-3-methylamino-N-...)
Affinity DataKi:  1.30nMAssay Description:Inhibition of [3H]U-69,593 binding to human Opioid receptor kappa 1 expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50086367(3-(3-Hydroxy-phenyl)-2,2-dimethyl-3-methylamino-N-...)
Affinity DataKi:  1.40nMAssay Description:Inhibition of [3H]-DAMGO binding to rat Opioid receptor mu 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50086361(3-(3-Hydroxy-phenyl)-2,2-dimethyl-3-methylamino-N-...)
Affinity DataKi:  1.40nMAssay Description:Inhibition of [3H]-DAMGO binding to rat Opioid receptor mu 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50000788((morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-az...)
Affinity DataKi:  1.40nMAssay Description:Inhibition of [3H]-DAMGO binding to rat Opioid receptor mu 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50086363(3-(Cyclopropylmethyl-methyl-amino)-3-(3-hydroxy-ph...)
Affinity DataKi:  2.90nMAssay Description:Inhibition of [3H]U-69,593 binding to human Opioid receptor kappa 1 expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50086366(3-(3-Hydroxy-phenyl)-2,2-dimethyl-3-methylamino-N-...)
Affinity DataKi:  3.60nMAssay Description:Inhibition of [3H]U-69,593 binding to human Opioid receptor kappa 1 expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50086360(CHEMBL347531 | N-Cyclohexylmethyl-3-(3-hydroxy-phe...)
Affinity DataKi:  4.40nMAssay Description:Inhibition of [3H]-DAMGO binding to rat Opioid receptor mu 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50086364(CHEMBL146750 | N-Benzyl-3-(3-hydroxy-phenyl)-2,2-d...)
Affinity DataKi:  5nMAssay Description:Inhibition of [3H]U-69,593 binding to human Opioid receptor kappa 1 expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50086360(CHEMBL347531 | N-Cyclohexylmethyl-3-(3-hydroxy-phe...)
Affinity DataKi:  5.70nMAssay Description:Inhibition of [3H]U-69,593 binding to human Opioid receptor kappa 1 expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50086367(3-(3-Hydroxy-phenyl)-2,2-dimethyl-3-methylamino-N-...)
Affinity DataKi:  6.30nMAssay Description:Inhibition of [3H]U-69,593 binding to human Opioid receptor kappa 1 expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50086364(CHEMBL146750 | N-Benzyl-3-(3-hydroxy-phenyl)-2,2-d...)
Affinity DataKi:  8.70nMAssay Description:Inhibition of [3H]-DAMGO binding to rat Opioid receptor mu 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50086366(3-(3-Hydroxy-phenyl)-2,2-dimethyl-3-methylamino-N-...)
Affinity DataKi:  12nMAssay Description:Inhibition of [3H]-DAMGO binding to rat Opioid receptor mu 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50086357(2,2-Dimethyl-3-methylamino-N-phenethyl-3-phenyl-pr...)
Affinity DataKi:  13nMAssay Description:Inhibition of [3H]-DAMGO binding to rat Opioid receptor mu 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50086365(3-(Butyl-methyl-amino)-3-(3-hydroxy-phenyl)-2,2-di...)
Affinity DataKi:  26nMAssay Description:Inhibition of [3H]-DAMGO binding to rat Opioid receptor mu 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50086363(3-(Cyclopropylmethyl-methyl-amino)-3-(3-hydroxy-ph...)
Affinity DataKi:  28nMAssay Description:Inhibition of [3H]-DAMGO binding to rat Opioid receptor mu 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50000788((morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-az...)
Affinity DataKi:  41nMAssay Description:Inhibition of [3H]-naltrindole binding to human Opioid receptor delta 1 in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetKappa-type opioid receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50086357(2,2-Dimethyl-3-methylamino-N-phenethyl-3-phenyl-pr...)
Affinity DataKi:  49nMAssay Description:Inhibition of [3H]U-69,593 binding to human Opioid receptor kappa 1 expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50086365(3-(Butyl-methyl-amino)-3-(3-hydroxy-phenyl)-2,2-di...)
Affinity DataKi:  75nMAssay Description:Inhibition of [3H]U-69,593 binding to human Opioid receptor kappa 1 expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50086358(CHEMBL347316 | N-Cyclopropylmethyl-3-(3-hydroxy-ph...)
Affinity DataKi:  75nMAssay Description:Inhibition of [3H]U-69,593 binding to human Opioid receptor kappa 1 expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50086359(CHEMBL147191 | N-Cyclohexylmethyl-2,2-dimethyl-3-m...)
Affinity DataKi:  85nMAssay Description:Inhibition of [3H]-DAMGO binding to rat Opioid receptor mu 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50086362(CHEMBL149143 | N-Benzyl-2,2-dimethyl-3-methylamino...)
Affinity DataKi:  95nMAssay Description:Inhibition of [3H]-DAMGO binding to rat Opioid receptor mu 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50086361(3-(3-Hydroxy-phenyl)-2,2-dimethyl-3-methylamino-N-...)
Affinity DataKi:  163nMAssay Description:Inhibition of [3H]-naltrindole binding to human Opioid receptor delta 1 in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50086367(3-(3-Hydroxy-phenyl)-2,2-dimethyl-3-methylamino-N-...)
Affinity DataKi:  176nMAssay Description:Inhibition of [3H]-naltrindole binding to human Opioid receptor delta 1 in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50086358(CHEMBL347316 | N-Cyclopropylmethyl-3-(3-hydroxy-ph...)
Affinity DataKi:  364nMAssay Description:Inhibition of [3H]-DAMGO binding to rat Opioid receptor mu 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50086362(CHEMBL149143 | N-Benzyl-2,2-dimethyl-3-methylamino...)
Affinity DataKi:  467nMAssay Description:Inhibition of [3H]U-69,593 binding to human Opioid receptor kappa 1 expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50086363(3-(Cyclopropylmethyl-methyl-amino)-3-(3-hydroxy-ph...)
Affinity DataKi:  710nMAssay Description:Inhibition of [3H]-naltrindole binding to human Opioid receptor delta 1 in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50086358(CHEMBL347316 | N-Cyclopropylmethyl-3-(3-hydroxy-ph...)
Affinity DataKi:  781nMAssay Description:Inhibition of [3H]-naltrindole binding to human Opioid receptor delta 1 in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50086360(CHEMBL347531 | N-Cyclohexylmethyl-3-(3-hydroxy-phe...)
Affinity DataKi:  881nMAssay Description:Inhibition of [3H]-naltrindole binding to human Opioid receptor delta 1 in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50086362(CHEMBL149143 | N-Benzyl-2,2-dimethyl-3-methylamino...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of [3H]-naltrindole binding to human Opioid receptor delta 1 in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50086364(CHEMBL146750 | N-Benzyl-3-(3-hydroxy-phenyl)-2,2-d...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of [3H]-naltrindole binding to human Opioid receptor delta 1 in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50086365(3-(Butyl-methyl-amino)-3-(3-hydroxy-phenyl)-2,2-di...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of [3H]-naltrindole binding to human Opioid receptor delta 1 in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50086359(CHEMBL147191 | N-Cyclohexylmethyl-2,2-dimethyl-3-m...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of [3H]-naltrindole binding to human Opioid receptor delta 1 in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50086357(2,2-Dimethyl-3-methylamino-N-phenethyl-3-phenyl-pr...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of [3H]-naltrindole binding to human Opioid receptor delta 1 in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50086366(3-(3-Hydroxy-phenyl)-2,2-dimethyl-3-methylamino-N-...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of [3H]-naltrindole binding to human Opioid receptor delta 1 in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed