Compile Data Set for Download or QSAR
maximum 50k data
Found 45 Enz. Inhib. hit(s) with all data for entry = 50012615
TargetCathepsin K(Homo sapiens (Human))
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121041(CHEMBL326093 | [(S)-1-((R)-4,7-Dioxo-4-(S)-oxo-4la...)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of Cbz-Phe-Arg-AMC binding to Cathepsin K cysteine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121039(CHEMBL114410 | [(S)-2-Cyclohexyl-1-((5S,6R)-4,4,7-...)
Affinity DataIC50:  0.700nMAssay Description:In vitro Inhibitory activity of the compound was determined against Cathepsin S cysteine protease by using Cbz-Val-Arg-AMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Rattus norvegicus)
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121039(CHEMBL114410 | [(S)-2-Cyclohexyl-1-((5S,6R)-4,4,7-...)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of Cbz-Phe-Arg-AMC binding to Cathepsin L cysteine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Rattus norvegicus)
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121041(CHEMBL326093 | [(S)-1-((R)-4,7-Dioxo-4-(S)-oxo-4la...)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of Cbz-Phe-Arg-AMC binding to Cathepsin L cysteine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Rattus norvegicus)
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121040(CHEMBL117928 | [(S)-2-Pyridin-3-yl-1-((5S,6R)-4,4,...)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of Cbz-Phe-Arg-AMC binding to Cathepsin L cysteine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121038(CHEMBL113706 | [(S)-2-Thiophen-2-yl-1-((5S,6R)-4,4...)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of Cbz-Phe-Arg-AMC binding to Cathepsin K cysteine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121040(CHEMBL117928 | [(S)-2-Pyridin-3-yl-1-((5S,6R)-4,4,...)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of Cbz-Phe-Arg-AMC binding to Cathepsin K cysteine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Rattus norvegicus)
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121038(CHEMBL113706 | [(S)-2-Thiophen-2-yl-1-((5S,6R)-4,4...)
Affinity DataIC50:  3nMAssay Description:Inhibition of Cbz-Phe-Arg-AMC binding to Cathepsin L cysteine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Rattus norvegicus)
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121044(CHEMBL116041 | [(S)-2-(3-Fluoro-phenyl)-1-((5S,6R)...)
Affinity DataIC50:  3nMAssay Description:Inhibition of Cbz-Phe-Arg-AMC binding to Cathepsin L cysteine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Rattus norvegicus)
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121042(CHEMBL323638 | [(S)-2-Naphthalen-2-yl-1-((5S,6R)-4...)
Affinity DataIC50:  3nMAssay Description:Inhibition of Cbz-Phe-Arg-AMC binding to Cathepsin L cysteine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121042(CHEMBL323638 | [(S)-2-Naphthalen-2-yl-1-((5S,6R)-4...)
Affinity DataIC50:  3nMAssay Description:In vitro Inhibitory activity of the compound was determined against Cathepsin S cysteine protease by using Cbz-Val-Arg-AMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121038(CHEMBL113706 | [(S)-2-Thiophen-2-yl-1-((5S,6R)-4,4...)
Affinity DataIC50:  4.60nMAssay Description:In vitro Inhibitory activity of the compound was determined against Cathepsin S cysteine protease by using Cbz-Val-Arg-AMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121034(CHEMBL332025 | [1-((S)-7-Oxo-4-oxa-1-aza-bicyclo[3...)
Affinity DataIC50:  5nMAssay Description:Inhibition of Cbz-Phe-Arg-AMC binding to Cathepsin K cysteine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121044(CHEMBL116041 | [(S)-2-(3-Fluoro-phenyl)-1-((5S,6R)...)
Affinity DataIC50:  6nMAssay Description:Inhibition of Cbz-Phe-Arg-AMC binding to Cathepsin K cysteine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121043(CHEMBL323637 | [(S)-1-((R)-4,7-Dioxo-4-(R)-oxo-4la...)
Affinity DataIC50:  7.5nMAssay Description:Inhibition of Cbz-Phe-Arg-AMC binding to Cathepsin K cysteine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121039(CHEMBL114410 | [(S)-2-Cyclohexyl-1-((5S,6R)-4,4,7-...)
Affinity DataIC50:  7.60nMAssay Description:Inhibition of Cbz-Phe-Arg-AMC binding to Cathepsin K cysteine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121044(CHEMBL116041 | [(S)-2-(3-Fluoro-phenyl)-1-((5S,6R)...)
Affinity DataIC50:  8nMAssay Description:In vitro Inhibitory activity of the compound was determined against Cathepsin S cysteine protease by using Cbz-Val-Arg-AMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Rattus norvegicus)
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121043(CHEMBL323637 | [(S)-1-((R)-4,7-Dioxo-4-(R)-oxo-4la...)
Affinity DataIC50:  9.60nMAssay Description:Inhibition of Cbz-Phe-Arg-AMC binding to Cathepsin L cysteine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121041(CHEMBL326093 | [(S)-1-((R)-4,7-Dioxo-4-(S)-oxo-4la...)
Affinity DataIC50:  10nMAssay Description:In vitro Inhibitory activity of the compound was determined against Cathepsin S cysteine protease by using Cbz-Val-Arg-AMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121035(CHEMBL326342 | [(S)-1-((R)-4-(S)-Oxo-7-oxo-4lambda...)
Affinity DataIC50:  35nMAssay Description:Inhibition of Cbz-Phe-Arg-AMC binding to Cathepsin K cysteine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121040(CHEMBL117928 | [(S)-2-Pyridin-3-yl-1-((5S,6R)-4,4,...)
Affinity DataIC50:  58nMAssay Description:In vitro Inhibitory activity of the compound was determined against Cathepsin S cysteine protease by using Cbz-Val-Arg-AMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Rattus norvegicus)
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121035(CHEMBL326342 | [(S)-1-((R)-4-(S)-Oxo-7-oxo-4lambda...)
Affinity DataIC50:  68nMAssay Description:Inhibition of Cbz-Phe-Arg-AMC binding to Cathepsin L cysteine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121035(CHEMBL326342 | [(S)-1-((R)-4-(S)-Oxo-7-oxo-4lambda...)
Affinity DataIC50:  70nMAssay Description:In vitro Inhibitory activity of the compound was determined against Cathepsin S cysteine protease by using Cbz-Val-Arg-AMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121043(CHEMBL323637 | [(S)-1-((R)-4,7-Dioxo-4-(R)-oxo-4la...)
Affinity DataIC50:  210nMAssay Description:In vitro Inhibitory activity of the compound was determined against Cathepsin S cysteine protease by using Cbz-Val-Arg-AMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121041(CHEMBL326093 | [(S)-1-((R)-4,7-Dioxo-4-(S)-oxo-4la...)
Affinity DataIC50:  350nMAssay Description:Inhibitory activity of Cbz-Phe-Arg-AMC against Cathepsin B cysteine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121042(CHEMBL323638 | [(S)-2-Naphthalen-2-yl-1-((5S,6R)-4...)
Affinity DataIC50:  390nMAssay Description:Inhibitory activity of Cbz-Phe-Arg-AMC against Cathepsin B cysteine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121042(CHEMBL323638 | [(S)-2-Naphthalen-2-yl-1-((5S,6R)-4...)
Affinity DataIC50:  400nMAssay Description:Inhibition of Cbz-Phe-Arg-AMC binding to Cathepsin K cysteine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121038(CHEMBL113706 | [(S)-2-Thiophen-2-yl-1-((5S,6R)-4,4...)
Affinity DataIC50:  430nMAssay Description:Inhibitory activity of Cbz-Phe-Arg-AMC against Cathepsin B cysteine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121039(CHEMBL114410 | [(S)-2-Cyclohexyl-1-((5S,6R)-4,4,7-...)
Affinity DataIC50:  430nMAssay Description:Inhibitory activity of Cbz-Phe-Arg-AMC against Cathepsin B cysteine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121044(CHEMBL116041 | [(S)-2-(3-Fluoro-phenyl)-1-((5S,6R)...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibitory activity of Cbz-Phe-Arg-AMC against Cathepsin B cysteine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121040(CHEMBL117928 | [(S)-2-Pyridin-3-yl-1-((5S,6R)-4,4,...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibitory activity of Cbz-Phe-Arg-AMC against Cathepsin B cysteine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121036(CHEMBL421054 | [(S)-1-((R)-7-Oxo-4-thia-1-aza-bicy...)
Affinity DataIC50: >2.50E+3nMAssay Description:Inhibition of Cbz-Phe-Arg-AMC binding to Cathepsin K cysteine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121033(CHEMBL115822 | [(S)-2-Phenyl-1-((6R,7R)-5,5,8-trio...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of Cbz-Phe-Arg-AMC binding to Cathepsin K cysteine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121037(CHEMBL323704 | [(S)-2-Phenyl-1-((2S,7R)-5,5,8-trio...)
Affinity DataIC50: >2.50E+3nMAssay Description:Inhibition of Cbz-Phe-Arg-AMC binding to Cathepsin K cysteine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121037(CHEMBL323704 | [(S)-2-Phenyl-1-((2S,7R)-5,5,8-trio...)
Affinity DataIC50: >2.50E+3nMAssay Description:In vitro Inhibitory activity of the compound was determined against Cathepsin S cysteine protease by using Cbz-Val-Arg-AMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121033(CHEMBL115822 | [(S)-2-Phenyl-1-((6R,7R)-5,5,8-trio...)
Affinity DataIC50:  2.50E+3nMAssay Description:In vitro Inhibitory activity of the compound was determined against Cathepsin S cysteine protease by using Cbz-Val-Arg-AMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Rattus norvegicus)
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121034(CHEMBL332025 | [1-((S)-7-Oxo-4-oxa-1-aza-bicyclo[3...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of Cbz-Phe-Arg-AMC binding to Cathepsin L cysteine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121043(CHEMBL323637 | [(S)-1-((R)-4,7-Dioxo-4-(R)-oxo-4la...)
Affinity DataIC50:  6.01E+3nMAssay Description:Inhibitory activity of Cbz-Phe-Arg-AMC against Cathepsin B cysteine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Rattus norvegicus)
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121036(CHEMBL421054 | [(S)-1-((R)-7-Oxo-4-thia-1-aza-bicy...)
Affinity DataIC50:  6.68E+3nMAssay Description:Inhibition of Cbz-Phe-Arg-AMC binding to Cathepsin L cysteine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Rattus norvegicus)
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121037(CHEMBL323704 | [(S)-2-Phenyl-1-((2S,7R)-5,5,8-trio...)
Affinity DataIC50:  1.06E+4nMAssay Description:Inhibition of Cbz-Phe-Arg-AMC binding to Cathepsin L cysteine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121035(CHEMBL326342 | [(S)-1-((R)-4-(S)-Oxo-7-oxo-4lambda...)
Affinity DataIC50:  1.64E+4nMAssay Description:Inhibitory activity of Cbz-Phe-Arg-AMC against Cathepsin B cysteine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121033(CHEMBL115822 | [(S)-2-Phenyl-1-((6R,7R)-5,5,8-trio...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibitory activity of Cbz-Phe-Arg-AMC against Cathepsin B cysteine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121037(CHEMBL323704 | [(S)-2-Phenyl-1-((2S,7R)-5,5,8-trio...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibitory activity of Cbz-Phe-Arg-AMC against Cathepsin B cysteine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121036(CHEMBL421054 | [(S)-1-((R)-7-Oxo-4-thia-1-aza-bicy...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibitory activity of Cbz-Phe-Arg-AMC against Cathepsin B cysteine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Rattus norvegicus)
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121033(CHEMBL115822 | [(S)-2-Phenyl-1-((6R,7R)-5,5,8-trio...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of Cbz-Phe-Arg-AMC binding to Cathepsin L cysteine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed