Compile Data Set for Download or QSAR
maximum 50k data
Found 15 Enz. Inhib. hit(s) with all data for entry = 50016030
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50163996(4-(4-Chloro-benzenesulfonyl)-4-(2-methoxy-phenyl)-...)
Affinity DataEC50:  1.03E+3nMAssay Description:In vitro inhibition of amyloid precursor protein 695 activity in CHO cells expressing human APPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50164002(4-Benzenesulfonyl-4-(2-methoxy-phenyl)-piperidine-...)
Affinity DataEC50:  6.27E+4nMAssay Description:In vitro effective concentration against beta amyloid protein 40 in ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50163996(4-(4-Chloro-benzenesulfonyl)-4-(2-methoxy-phenyl)-...)
Affinity DataEC50:  530nMAssay Description:In vitro reduction of Swedish NL mutant amyloid precursor protein activity expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50163997(4-(4-Methoxy-benzenesulfonyl)-4-phenyl-piperidine-...)
Affinity DataEC50:  9.70E+4nMAssay Description:In vitro effective concentration against beta amyloid protein 40 in ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50163996(4-(4-Chloro-benzenesulfonyl)-4-(2-methoxy-phenyl)-...)
Affinity DataEC50:  5.00E+3nMAssay Description:In vitro effective concentration against beta amyloid protein 42 in ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM28960((2R)-2-{[5-chloro-2-(hydroxymethyl)phenyl](4-chlor...)
Affinity DataEC50:  100nMAssay Description:In vitro effective concentration against beta amyloid protein 40 in ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50163998(4-(4-Methoxy-benzenesulfonyl)-4-o-tolyl-piperidine...)
Affinity DataEC50:  2.45E+4nMAssay Description:In vitro effective concentration against beta amyloid protein 40 in ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50163999(4-(4-Chloro-benzenesulfonyl)-4-o-tolyl-piperidine-...)
Affinity DataEC50:  3.70E+3nMAssay Description:In vitro effective concentration against beta amyloid protein 42 in ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50164000(4-(4-Methoxy-benzenesulfonyl)-4-(2-methoxy-phenyl)...)
Affinity DataEC50:  5.06E+4nMAssay Description:In vitro effective concentration against beta amyloid protein 40 in ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50163996(4-(4-Chloro-benzenesulfonyl)-4-(2-methoxy-phenyl)-...)
Affinity DataEC50:  3.50E+3nMAssay Description:In vitro effective concentration against beta amyloid protein 40 in ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM28961(CHEMBL180641 | ethyl 4-[(4-chlorobenzene)sulfonyl]...)
Affinity DataEC50:  1.22E+4nMAssay Description:In vitro effective concentration against beta amyloid protein 40 in ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50163999(4-(4-Chloro-benzenesulfonyl)-4-o-tolyl-piperidine-...)
Affinity DataEC50:  2.70E+3nMAssay Description:In vitro effective concentration against beta amyloid protein 40 in ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50163996(4-(4-Chloro-benzenesulfonyl)-4-(2-methoxy-phenyl)-...)
Affinity DataEC50:  640nMAssay Description:In vitro elevation of beta C-terminal fragment (Ct-99) in CHO cells expressing mutant Swedish NL human APPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50164001(4-Benzenesulfonyl-4-o-tolyl-piperidine-1-carboxyli...)
Affinity DataEC50:  4.86E+4nMAssay Description:In vitro effective concentration against beta amyloid protein 40 in ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM28961(CHEMBL180641 | ethyl 4-[(4-chlorobenzene)sulfonyl]...)
Affinity DataEC50:  2.09E+4nMAssay Description:In vitro effective concentration against beta amyloid protein 42 in ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed