TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
National Institute On Drug Abuse
Curated by ChEMBL
National Institute On Drug Abuse
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of [3H]MPEP binding to mGluR5 in rat brain membraneMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
National Institute On Drug Abuse
Curated by ChEMBL
National Institute On Drug Abuse
Curated by ChEMBL
Affinity DataIC50: 39nMAssay Description:Antagonist activity against mGluR5 expressed in CHO cells assessed as inhibition of agonist-induced phosphoinositide hydrolysisMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
National Institute On Drug Abuse
Curated by ChEMBL
National Institute On Drug Abuse
Curated by ChEMBL
Affinity DataIC50: 330nMAssay Description:Inhibition of [3H]MPEP binding to mGluR5 in rat brain membraneMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
National Institute On Drug Abuse
Curated by ChEMBL
National Institute On Drug Abuse
Curated by ChEMBL
Affinity DataIC50: 462nMAssay Description:Antagonist activity against mGluR5 expressed in CHO cells assessed as inhibition of agonist-induced phosphoinositide hydrolysisMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
National Institute On Drug Abuse
Curated by ChEMBL
National Institute On Drug Abuse
Curated by ChEMBL
Affinity DataIC50: 650nMAssay Description:Inhibition of [3H]MPEP binding to mGluR5 in rat brain membraneMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
National Institute On Drug Abuse
Curated by ChEMBL
National Institute On Drug Abuse
Curated by ChEMBL
Affinity DataIC50: 1.08E+3nMAssay Description:Inhibition of [3H]MPEP binding to mGluR5 in rat brain membraneMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
National Institute On Drug Abuse
Curated by ChEMBL
National Institute On Drug Abuse
Curated by ChEMBL
Affinity DataIC50: 1.08E+3nMAssay Description:Inhibition of [3H]MPEP binding to mGluR5 in rat brain membraneMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
National Institute On Drug Abuse
Curated by ChEMBL
National Institute On Drug Abuse
Curated by ChEMBL
Affinity DataIC50: 1.17E+3nMAssay Description:Inhibition of [3H]MPEP binding to mGluR5 in rat brain membraneMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
National Institute On Drug Abuse
Curated by ChEMBL
National Institute On Drug Abuse
Curated by ChEMBL
Affinity DataIC50: 1.17E+3nMAssay Description:Inhibition of [3H]MPEP binding to mGluR5 in rat brain membraneMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
National Institute On Drug Abuse
Curated by ChEMBL
National Institute On Drug Abuse
Curated by ChEMBL
Affinity DataIC50: 1.53E+3nMAssay Description:Inhibition of [3H]MPEP binding to mGluR5 in rat brain membraneMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
National Institute On Drug Abuse
Curated by ChEMBL
National Institute On Drug Abuse
Curated by ChEMBL
Affinity DataIC50: 1.84E+3nMAssay Description:Inhibition of [3H]MPEP binding to mGluR5 in rat brain membraneMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
National Institute On Drug Abuse
Curated by ChEMBL
National Institute On Drug Abuse
Curated by ChEMBL
Affinity DataIC50: 5.33E+3nMAssay Description:Antagonist activity against mGluR5 expressed in CHO cells assessed as inhibition of agonist-induced phosphoinositide hydrolysisMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
National Institute On Drug Abuse
Curated by ChEMBL
National Institute On Drug Abuse
Curated by ChEMBL
Affinity DataIC50: 5.48E+3nMAssay Description:Antagonist activity against mGluR5 expressed in CHO cells assessed as inhibition of agonist-induced phosphoinositide hydrolysisMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
National Institute On Drug Abuse
Curated by ChEMBL
National Institute On Drug Abuse
Curated by ChEMBL
Affinity DataIC50: 5.49E+3nMAssay Description:Inhibition of [3H]MPEP binding to mGluR5 in rat brain membraneMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
National Institute On Drug Abuse
Curated by ChEMBL
National Institute On Drug Abuse
Curated by ChEMBL
Affinity DataIC50: 5.90E+3nMAssay Description:Antagonist activity against mGluR5 expressed in CHO cells assessed as inhibition of agonist-induced phosphoinositide hydrolysisMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
National Institute On Drug Abuse
Curated by ChEMBL
National Institute On Drug Abuse
Curated by ChEMBL
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibition of [3H]MPEP binding to mGluR5 in rat brain membraneMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
National Institute On Drug Abuse
Curated by ChEMBL
National Institute On Drug Abuse
Curated by ChEMBL
Affinity DataIC50: 9.10E+3nMAssay Description:Inhibition of [3H]MPEP binding to mGluR5 in rat brain membraneMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
National Institute On Drug Abuse
Curated by ChEMBL
National Institute On Drug Abuse
Curated by ChEMBL
Affinity DataIC50: 9.76E+3nMAssay Description:Inhibition of [3H]MPEP binding to mGluR5 in rat brain membraneMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
National Institute On Drug Abuse
Curated by ChEMBL
National Institute On Drug Abuse
Curated by ChEMBL
Affinity DataIC50: 1.08E+4nMAssay Description:Antagonist activity against mGluR5 expressed in CHO cells assessed as inhibition of agonist-induced phosphoinositide hydrolysisMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
National Institute On Drug Abuse
Curated by ChEMBL
National Institute On Drug Abuse
Curated by ChEMBL
Affinity DataIC50: 1.27E+4nMAssay Description:Antagonist activity against mGluR5 expressed in CHO cells assessed as inhibition of agonist-induced phosphoinositide hydrolysisMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
National Institute On Drug Abuse
Curated by ChEMBL
National Institute On Drug Abuse
Curated by ChEMBL
Affinity DataIC50: 1.50E+4nMAssay Description:Antagonist activity against mGluR5 expressed in CHO cells assessed as inhibition of agonist-induced phosphoinositide hydrolysisMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
National Institute On Drug Abuse
Curated by ChEMBL
National Institute On Drug Abuse
Curated by ChEMBL
Affinity DataIC50: 1.83E+4nMAssay Description:Antagonist activity against mGluR5 expressed in CHO cells assessed as inhibition of agonist-induced phosphoinositide hydrolysisMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
National Institute On Drug Abuse
Curated by ChEMBL
National Institute On Drug Abuse
Curated by ChEMBL
Affinity DataIC50: 1.87E+4nMAssay Description:Inhibition of [3H]MPEP binding to mGluR5 in rat brain membraneMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
National Institute On Drug Abuse
Curated by ChEMBL
National Institute On Drug Abuse
Curated by ChEMBL
Affinity DataIC50: 2.36E+4nMAssay Description:Inhibition of [3H]MPEP binding to mGluR5 in rat brain membraneMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
National Institute On Drug Abuse
Curated by ChEMBL
National Institute On Drug Abuse
Curated by ChEMBL
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of [3H]MPEP binding to mGluR5 in rat brain membraneMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
National Institute On Drug Abuse
Curated by ChEMBL
National Institute On Drug Abuse
Curated by ChEMBL
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of [3H]MPEP binding to mGluR5 in rat brain membraneMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
National Institute On Drug Abuse
Curated by ChEMBL
National Institute On Drug Abuse
Curated by ChEMBL
Affinity DataIC50: 4.60E+4nMAssay Description:Antagonist activity against mGluR5 expressed in CHO cells assessed as inhibition of agonist-induced phosphoinositide hydrolysisMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
National Institute On Drug Abuse
Curated by ChEMBL
National Institute On Drug Abuse
Curated by ChEMBL
Affinity DataIC50: 5.70E+4nMAssay Description:Inhibition of [3H]MPEP binding to mGluR5 in rat brain membraneMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
National Institute On Drug Abuse
Curated by ChEMBL
National Institute On Drug Abuse
Curated by ChEMBL
Affinity DataIC50: 6.28E+4nMAssay Description:Inhibition of [3H]MPEP binding to mGluR5 in rat brain membraneMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
National Institute On Drug Abuse
Curated by ChEMBL
National Institute On Drug Abuse
Curated by ChEMBL
Affinity DataIC50: 6.50E+4nMAssay Description:Inhibition of [3H]MPEP binding to mGluR5 in rat brain membraneMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
National Institute On Drug Abuse
Curated by ChEMBL
National Institute On Drug Abuse
Curated by ChEMBL
Affinity DataIC50: 8.36E+4nMAssay Description:Inhibition of [3H]MPEP binding to mGluR5 in rat brain membraneMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
National Institute On Drug Abuse
Curated by ChEMBL
National Institute On Drug Abuse
Curated by ChEMBL
Affinity DataIC50: 9.54E+4nMAssay Description:Inhibition of [3H]MPEP binding to mGluR5 in rat brain membraneMore data for this Ligand-Target Pair