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Found 20 Enz. Inhib. hit(s) with all data for entry = 50028192
TargetThrombopoietin receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50247935((R)-2-(3-chloro-5-(4-(2-fluoro-3-(trifluoromethyl)...)
Affinity DataEC50:  57nMAssay Description:Agonist activity at human thrombopoietin receptor transfected in mouse BAF3 cells assessed as stimulation of beta lactamase activity incubated in dar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50248582((4R)-1-(3-chloro-5-(4-(2-fluoro-3-(trifluoromethyl...)
Affinity DataEC50:  43nMAssay Description:Agonist activity at human thrombopoietin receptor transfected in mouse BAF3 cells assessed as stimulation of beta lactamase activity incubated in dar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50247937(1-(3-chloro-5-(4-(2-fluoro-3-(trifluoromethyl)phen...)
Affinity DataEC50:  294nMAssay Description:Agonist activity at human thrombopoietin receptor transfected in mouse BAF3 cells assessed as stimulation of beta lactamase activity incubated in dar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50247938(1-(5-(4-(2-fluoro-3-(trifluoromethyl)phenyl)thiazo...)
Affinity DataEC50:  430nMAssay Description:Agonist activity at human thrombopoietin receptor transfected in mouse BAF3 cells assessed as stimulation of beta lactamase activity incubated in dar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50247965(6-(4-(2H-tetrazol-5-yl)piperidin-1-yl)-5-chloro-N-...)
Affinity DataEC50:  485nMAssay Description:Agonist activity at human thrombopoietin receptor transfected in mouse BAF3 cells assessed as stimulation of beta lactamase activity incubated in dar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50248022(5-chloro-N-(4-(2-fluoro-3-(trifluoromethyl)phenyl)...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human thrombopoietin receptor transfected in mouse BAF3 cells assessed as stimulation of beta lactamase activity incubated in dar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50248023(1-(2,6-dichloro-4-(4-(2-fluoro-3-(trifluoromethyl)...)
Affinity DataEC50:  10nMAssay Description:Agonist activity at human thrombopoietin receptor transfected in mouse BAF3 cells assessed as stimulation of beta lactamase activity incubated in dar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50248024(1-(3-bromo-5-(4-(2-fluoro-3-(trifluoromethyl)pheny...)
Affinity DataEC50:  50nMAssay Description:Agonist activity at human thrombopoietin receptor transfected in mouse BAF3 cells assessed as stimulation of beta lactamase activity incubated in dar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50248025(1-(2-chloro-4-(4-(2-fluoro-3-(trifluoromethyl)phen...)
Affinity DataEC50:  56nMAssay Description:Agonist activity at human thrombopoietin receptor transfected in mouse BAF3 cells assessed as stimulation of beta lactamase activity incubated in dar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50248068(1-(5-(4-(2-fluoro-3-(trifluoromethyl)phenyl)thiazo...)
Affinity DataEC50:  134nMAssay Description:Agonist activity at human thrombopoietin receptor transfected in mouse BAF3 cells assessed as stimulation of beta lactamase activity incubated in dar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50248069(1-(3-cyano-5-(4-(2-fluoro-3-(trifluoromethyl)pheny...)
Affinity DataEC50:  138nMAssay Description:Agonist activity at human thrombopoietin receptor transfected in mouse BAF3 cells assessed as stimulation of beta lactamase activity incubated in dar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50248070(1-(5-(4-(2-fluoro-3-(trifluoromethyl)phenyl)thiazo...)
Affinity DataEC50:  253nMAssay Description:Agonist activity at human thrombopoietin receptor transfected in mouse BAF3 cells assessed as stimulation of beta lactamase activity incubated in dar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50248071(1-(3-fluoro-5-(4-(2-fluoro-3-(trifluoromethyl)phen...)
Affinity DataEC50: >1.00E+3nMAssay Description:Agonist activity at human thrombopoietin receptor transfected in mouse BAF3 cells assessed as stimulation of beta lactamase activity incubated in dar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50248105(1-(5-(4-(2-fluoro-3-(trifluoromethyl)phenyl)thiazo...)
Affinity DataEC50: >1.00E+3nMAssay Description:Agonist activity at human thrombopoietin receptor transfected in mouse BAF3 cells assessed as stimulation of beta lactamase activity incubated in dar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50219622(CHEMBL429295 | N-(4-(2-fluoro-3-(trifluoromethoxy)...)
Affinity DataEC50:  7nMAssay Description:Agonist activity at human thrombopoietin receptor transfected in mouse BAF3 cells assessed as stimulation of beta lactamase activity incubated in dar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50248531(1-(3-chloro-5-(4-(2-fluoro-3-(trifluoromethyl)phen...)
Affinity DataEC50:  33nMAssay Description:Agonist activity at human thrombopoietin receptor transfected in mouse BAF3 cells assessed as stimulation of beta lactamase activity incubated in dar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50248579(1-(5-(4-(2-fluoro-3-(trifluoromethyl)phenyl)thiazo...)
Affinity DataEC50:  3.30E+3nMAssay Description:Agonist activity at human thrombopoietin receptor transfected in mouse BAF3 cells assessed as stimulation of beta lactamase activity incubated in dar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50248580(6-(4-carbamoylpiperidin-1-yl)-5-chloro-N-(4-(2-flu...)
Affinity DataEC50:  28nMAssay Description:Agonist activity at human thrombopoietin receptor transfected in mouse BAF3 cells assessed as stimulation of beta lactamase activity incubated in dar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50248581(5-chloro-N-(4-(2-fluoro-3-(trifluoromethyl)phenyl)...)
Affinity DataEC50:  34nMAssay Description:Agonist activity at human thrombopoietin receptor transfected in mouse BAF3 cells assessed as stimulation of beta lactamase activity incubated in dar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50247936(4-(3-chloro-5-(4-(2-fluoro-3-(trifluoromethyl)phen...)
Affinity DataEC50:  129nMAssay Description:Agonist activity at human thrombopoietin receptor transfected in mouse BAF3 cells assessed as stimulation of beta lactamase activity incubated in dar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed