Compile Data Set for Download or QSAR
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Found 25 Enz. Inhib. hit(s) with all data for entry = 50030773
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301193(6-((5-ethyl-4-(fluoromethyl)thiazol-2-ylthio)methy...)
Affinity DataIC50:  0.130nMAssay Description:Displacement of [125I]-PYY from human NPYY1 receptor overexpressed in CHO cell membrane after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301204(6-((4,5-dimethyloxazol-2-ylthio)methyl)-N-((6-meth...)
Affinity DataIC50:  0.160nMAssay Description:Displacement of [125I]-PYY from human NPYY1 receptor overexpressed in CHO cell membrane after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301192(6-((4-(fluoromethyl)-5-methylthiazol-2-ylthio)meth...)
Affinity DataIC50:  0.200nMAssay Description:Displacement of [125I]-PYY from human NPYY1 receptor overexpressed in CHO cell membrane after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301203(6-((4,5-dimethyloxazol-2-ylthio)methyl)-N-((6-fluo...)
Affinity DataIC50:  0.270nMAssay Description:Displacement of [125I]-PYY from human NPYY1 receptor overexpressed in CHO cell membrane after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301209(6-((4,5-dimethylthiazol-2-ylthio)methyl)-N-((6-met...)
Affinity DataIC50:  0.270nMAssay Description:Displacement of [125I]-PYY from human NPYY1 receptor overexpressed in CHO cell membrane after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301207(6-((5-ethyl-4-methyloxazol-2-ylthio)methyl)-N-((6-...)
Affinity DataIC50:  0.390nMAssay Description:Displacement of [125I]-PYY from human NPYY1 receptor overexpressed in CHO cell membrane after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301208(CHEMBL566040 | N-((6-methylpyridin-2-yl)methyl)-4-...)
Affinity DataIC50:  0.460nMAssay Description:Displacement of [125I]-PYY from human NPYY1 receptor overexpressed in CHO cell membrane after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301210(6-((5-(fluoromethyl)-4-methylthiazol-2-ylthio)meth...)
Affinity DataIC50:  0.560nMAssay Description:Displacement of [125I]-PYY from human NPYY1 receptor overexpressed in CHO cell membrane after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301202(6-((4,5-dimethyloxazol-2-ylthio)methyl)-N-((6-meth...)
Affinity DataIC50:  0.690nMAssay Description:Displacement of [125I]-PYY from human NPYY1 receptor overexpressed in CHO cell membrane after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301197(6-((4,5-dimethyloxazol-2-ylthio)methyl)-N-((6-fluo...)
Affinity DataIC50:  1.5nMAssay Description:Displacement of [125I]-PYY from human NPYY1 receptor overexpressed in CHO cell membrane after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301206(CHEMBL566889 | [6-(4,5-Dimethyl-oxazol-2-ylsulfany...)
Affinity DataIC50:  1.70nMAssay Description:Displacement of [125I]-PYY from human NPYY1 receptor overexpressed in CHO cell membrane after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301200(6-((4,5-dimethyloxazol-2-ylthio)methyl)-N-((6-(flu...)
Affinity DataIC50:  1.80nMAssay Description:Displacement of [125I]-PYY from human NPYY1 receptor overexpressed in CHO cell membrane after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301198(6-((4,5-dimethyloxazol-2-ylthio)methyl)-N-((6-(met...)
Affinity DataIC50:  4.30nMAssay Description:Displacement of [125I]-PYY from human NPYY1 receptor overexpressed in CHO cell membrane after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301196(6-((4,5-dimethyloxazol-2-ylthio)methyl)-N-((2-fluo...)
Affinity DataIC50:  5.20nMAssay Description:Displacement of [125I]-PYY from human NPYY1 receptor overexpressed in CHO cell membrane after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301195(6-((4,5-dimethyloxazol-2-ylthio)methyl)-N-((2-fluo...)
Affinity DataIC50:  7.70nMAssay Description:Displacement of [125I]-PYY from human NPYY1 receptor overexpressed in CHO cell membrane after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301205(CHEMBL566441 | [6-(4,5-Dimethyl-oxazol-2-ylsulfany...)
Affinity DataIC50:  8nMAssay Description:Displacement of [125I]-PYY from human NPYY1 receptor overexpressed in CHO cell membrane after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301199(6-((4,5-dimethyloxazol-2-ylthio)methyl)-N-((6-((2-...)
Affinity DataIC50:  10nMAssay Description:Displacement of [125I]-PYY from human NPYY1 receptor overexpressed in CHO cell membrane after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301201(6-((4,5-dimethyloxazol-2-ylthio)methyl)-N-((6-(2-f...)
Affinity DataIC50:  19nMAssay Description:Displacement of [125I]-PYY from human NPYY1 receptor overexpressed in CHO cell membrane after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301194(6-((4,5-dimethyloxazol-2-ylthio)methyl)-N-((6-fluo...)
Affinity DataIC50:  21nMAssay Description:Displacement of [125I]-PYY from human NPYY1 receptor overexpressed in CHO cell membrane after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301192(6-((4-(fluoromethyl)-5-methylthiazol-2-ylthio)meth...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [125I]-PYY from human NPYY2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 4(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301192(6-((4-(fluoromethyl)-5-methylthiazol-2-ylthio)meth...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [125I]-PYY from human NPYY4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301192(6-((4-(fluoromethyl)-5-methylthiazol-2-ylthio)meth...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [125I]-PYY from human NPYY5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301193(6-((5-ethyl-4-(fluoromethyl)thiazol-2-ylthio)methy...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [125I]-PYY from human NPYY2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 4(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301193(6-((5-ethyl-4-(fluoromethyl)thiazol-2-ylthio)methy...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [125I]-PYY from human NPYY4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301193(6-((5-ethyl-4-(fluoromethyl)thiazol-2-ylthio)methy...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [125I]-PYY from human NPYY5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed