Compile Data Set for Download or QSAR
maximum 50k data
Found 47 Enz. Inhib. hit(s) with all data for entry = 50031495
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50314176(4-(1-(3-(5-(methylsulfonyl)-3-(3-(2-(piperidin-1-y...)
Affinity DataIC50:  30nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50314168(1-(1-(3-(5-(methylsulfonyl)-3-(3-(2-(piperidin-1-y...)
Affinity DataIC50:  40nMAssay Description:Inhibition of cathepsin S in human JY cells assessed as inhibition of invariant chain degradationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50314171(1-(1-(3-(5-(methylsulfonyl)-3-(3-(2-(octahydroisoq...)
Affinity DataIC50:  55nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50314164(1-(1-(3-(5-(methylsulfonyl)-3-(3-(2-(pyrrolidin-1-...)
Affinity DataIC50:  80nMAssay Description:Inhibition of cathepsin S in human JY cells assessed as inhibition of invariant chain degradationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50314170(1-(1-(3-(3-(3-(2-(4-methylpiperidin-1-yl)ethylthio...)
Affinity DataIC50:  110nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50314161(1-(1-(3-(3-(3-(2-(4-methylpiperazin-1-yl)ethylthio...)
Affinity DataIC50:  130nMAssay Description:Inhibition of cathepsin S in human JY cells assessed as inhibition of invariant chain degradationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50314181(CHEMBL1089278 | N-(2-(5-(1-(2-hydroxy-3-(4-(2-oxop...)
Affinity DataIC50:  130nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50314169(1-(1-(3-(3-(3-(2-(4-tert-butylpiperidin-1-yl)ethyl...)
Affinity DataIC50:  160nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50314168(1-(1-(3-(5-(methylsulfonyl)-3-(3-(2-(piperidin-1-y...)
Affinity DataIC50:  170nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50314167(1-(1-(3-(5-(methylsulfonyl)-3-(3-(2-(4-phenylpiper...)
Affinity DataIC50:  200nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50314157(1-(1-(3-(3-(3-(2-hydroxyethylthio)-4-(trifluoromet...)
Affinity DataIC50:  200nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50314176(4-(1-(3-(5-(methylsulfonyl)-3-(3-(2-(piperidin-1-y...)
Affinity DataIC50:  210nMAssay Description:Inhibition of cathepsin S in human JY cells assessed as inhibition of invariant chain degradationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50314156(1-(1-(3-(5-(methylsulfonyl)-3-(3-(2-phenoxyethylth...)
Affinity DataIC50:  220nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50314166(1-(1-(3-(5-(methylsulfonyl)-3-(3-(2-morpholinoethy...)
Affinity DataIC50:  270nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50314173(5-(methylsulfonyl)-3-(3-(2-(piperidin-1-yl)ethylth...)
Affinity DataIC50:  320nMAssay Description:Inhibition of cathepsin S in human JY cells assessed as inhibition of invariant chain degradationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50314169(1-(1-(3-(3-(3-(2-(4-tert-butylpiperidin-1-yl)ethyl...)
Affinity DataIC50:  330nMAssay Description:Inhibition of cathepsin S in human JY cells assessed as inhibition of invariant chain degradationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50314165(1-(1-(3-(3-(3-(2-(4-hydroxypiperidin-1-yl)ethylthi...)
Affinity DataIC50:  340nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50314165(1-(1-(3-(3-(3-(2-(4-hydroxypiperidin-1-yl)ethylthi...)
Affinity DataIC50:  350nMAssay Description:Inhibition of cathepsin S in human JY cells assessed as inhibition of invariant chain degradationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50314179(CHEMBL1089277 | rac-4-fluoro-N-(2-(5-(1-(2-hydroxy...)
Affinity DataIC50:  360nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50314175(5-(methylsulfonyl)-3-(3-(2-(piperidin-1-yl)ethylth...)
Affinity DataIC50:  380nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50314177(CHEMBL1089275 | rac-N-(2-(5-(1-(2-hydroxy-3-(4-(2-...)
Affinity DataIC50:  380nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50314175(5-(methylsulfonyl)-3-(3-(2-(piperidin-1-yl)ethylth...)
Affinity DataIC50:  380nMAssay Description:Inhibition of cathepsin S in human JY cells assessed as inhibition of invariant chain degradationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50314178(CHEMBL1089276 | rac-4-hydroxy-N-(2-(5-(1-(2-hydrox...)
Affinity DataIC50:  390nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50314164(1-(1-(3-(5-(methylsulfonyl)-3-(3-(2-(pyrrolidin-1-...)
Affinity DataIC50:  410nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50314182(CHEMBL1089279 | rac-N-(2-(5-(1-(2-hydroxy-3-(4-(2-...)
Affinity DataIC50:  420nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50314163(1-(1-(3-(3-(3-(2-(benzylamino)ethylthio)-4-(triflu...)
Affinity DataIC50:  460nMAssay Description:Inhibition of cathepsin S in human JY cells assessed as inhibition of invariant chain degradationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50314171(1-(1-(3-(5-(methylsulfonyl)-3-(3-(2-(octahydroisoq...)
Affinity DataIC50:  460nMAssay Description:Inhibition of cathepsin S in human JY cells assessed as inhibition of invariant chain degradationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50314174(5-(methylsulfonyl)-3-(3-(2-(piperidin-1-yl)ethylth...)
Affinity DataIC50:  470nMAssay Description:Inhibition of cathepsin S in human JY cells assessed as inhibition of invariant chain degradationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50314174(5-(methylsulfonyl)-3-(3-(2-(piperidin-1-yl)ethylth...)
Affinity DataIC50:  520nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50314180(CHEMBL1076796 | rac-4-(dimethylamino)-N-(2-(5-(1-(...)
Affinity DataIC50:  530nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50314173(5-(methylsulfonyl)-3-(3-(2-(piperidin-1-yl)ethylth...)
Affinity DataIC50:  560nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50314154(4-(3-(3-(4-chloro-3-(2-phenoxyethylthio)phenyl)-5-...)
Affinity DataIC50:  600nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50314166(1-(1-(3-(5-(methylsulfonyl)-3-(3-(2-morpholinoethy...)
Affinity DataIC50:  680nMAssay Description:Inhibition of cathepsin S in human JY cells assessed as inhibition of invariant chain degradationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50314163(1-(1-(3-(3-(3-(2-(benzylamino)ethylthio)-4-(triflu...)
Affinity DataIC50:  700nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50314155(4-(3-(5-(methylsulfonyl)-3-(3-(2-phenoxyethylthio)...)
Affinity DataIC50:  740nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50314162(1-(1-(3-(3-(3-(2-(methylamino)ethylthio)-4-(triflu...)
Affinity DataIC50:  800nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50314172(4-(3-(5-(methylsulfonyl)-3-(3-(2-(piperidin-1-yl)e...)
Affinity DataIC50:  810nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50314170(1-(1-(3-(3-(3-(2-(4-methylpiperidin-1-yl)ethylthio...)
Affinity DataIC50:  810nMAssay Description:Inhibition of cathepsin S in human JY cells assessed as inhibition of invariant chain degradationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50314167(1-(1-(3-(5-(methylsulfonyl)-3-(3-(2-(4-phenylpiper...)
Affinity DataIC50:  950nMAssay Description:Inhibition of cathepsin S in human JY cells assessed as inhibition of invariant chain degradationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50314158(2-(2-chloro-5-(5-(methylsulfonyl)-1-(3-morpholinop...)
Affinity DataIC50:  960nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50314161(1-(1-(3-(3-(3-(2-(4-methylpiperazin-1-yl)ethylthio...)
Affinity DataIC50:  1.06E+3nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50314160(1-(1-(3-(3-(3-(2-(dimethylamino)ethylthio)-4-(trif...)
Affinity DataIC50:  1.28E+3nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50314152(4-(3-(3-(4-chloro-3-(phenethylthio)phenyl)-5-(meth...)
Affinity DataIC50:  1.47E+3nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50314151(4-(3-(3-(3-(benzylthio)-4-chlorophenyl)-5-(methyls...)
Affinity DataIC50:  1.65E+3nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50314159(1-(1-(3-(3-(3-(2-(benzyl(methyl)amino)ethylthio)-4...)
Affinity DataIC50:  2.01E+3nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50314172(4-(3-(5-(methylsulfonyl)-3-(3-(2-(piperidin-1-yl)e...)
Affinity DataIC50:  3.57E+3nMAssay Description:Inhibition of cathepsin S in human JY cells assessed as inhibition of invariant chain degradationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50314153(4-(3-(3-(4-chloro-3-(propylthio)phenyl)-5-(methyls...)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed