Compile Data Set for Download or QSAR
maximum 50k data
Found 65 Enz. Inhib. hit(s) with all data for entry = 50031749
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50318308(4-((2-oxo-3-phenyloxazolidin-5-yl)methoxy)benzamid...)
Affinity DataEC50: >3.00E+4nMAssay Description:Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50318309(CHEMBL1096052 | N-(2-((2-oxo-3-phenyloxazolidin-5-...)
Affinity DataEC50: >3.00E+4nMAssay Description:Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50318310(CHEMBL1094429 | N-(3-((2-oxo-3-phenyloxazolidin-5-...)
Affinity DataEC50: >3.00E+4nMAssay Description:Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50318311(CHEMBL1094430 | N-(4-((2-oxo-3-phenyloxazolidin-5-...)
Affinity DataEC50: >3.00E+4nMAssay Description:Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50318312((R)-5-hexyl-3-phenyloxazolidin-2-one | CHEMBL10947...)
Affinity DataEC50:  450nMAssay Description:Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50318313(3-{(5S)-5-[(4-tert-butylphenoxy)methyl]-2-oxo-1,3-...)
Affinity DataEC50:  82nMAssay Description:Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50318312((R)-5-hexyl-3-phenyloxazolidin-2-one | CHEMBL10947...)
Affinity DataEC50:  1.38E+4nMAssay Description:Agonist activity at human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calcium f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50318313(3-{(5S)-5-[(4-tert-butylphenoxy)methyl]-2-oxo-1,3-...)
Affinity DataEC50:  4.90E+3nMAssay Description:Agonist activity at human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calcium f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50318314((R)-3-(5-((4-tert-butylphenoxy)methyl)-2-oxooxazol...)
Affinity DataEC50: >3.00E+4nMAssay Description:Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50318315(5-hexyl-3-o-tolyloxazolidin-2-one | CHEMBL1096081)
Affinity DataEC50: >3.00E+4nMAssay Description:Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50318316(5-hexyl-3-m-tolyloxazolidin-2-one | CHEMBL1096423)
Affinity DataEC50:  640nMAssay Description:Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50318317(5-hexyl-3-p-tolyloxazolidin-2-one | CHEMBL1095638)
Affinity DataEC50:  3.82E+3nMAssay Description:Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50318318(3-(2-fluorophenyl)-5-hexyloxazolidin-2-one | CHEMB...)
Affinity DataEC50:  7.15E+3nMAssay Description:Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50318319(3-(3-fluorophenyl)-5-hexyloxazolidin-2-one | CHEMB...)
Affinity DataEC50:  640nMAssay Description:Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50318320(3-(4-fluorophenyl)-5-hexyloxazolidin-2-one | CHEMB...)
Affinity DataEC50:  790nMAssay Description:Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50318321(3-(2-chlorophenyl)-5-hexyloxazolidin-2-one | CHEMB...)
Affinity DataEC50: >3.00E+4nMAssay Description:Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50318322(3-(3-chlorophenyl)-5-hexyloxazolidin-2-one | CHEMB...)
Affinity DataEC50:  590nMAssay Description:Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50318323(3-(4-chlorophenyl)-5-hexyloxazolidin-2-one | CHEMB...)
Affinity DataEC50:  4.45E+3nMAssay Description:Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50318324(2-(5-hexyl-2-oxooxazolidin-3-yl)benzonitrile | CHE...)
Affinity DataEC50:  1.76E+3nMAssay Description:Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50318325(3-(5-hexyl-2-oxo-1,3-oxazolidin-3-yl)benzonitrile ...)
Affinity DataEC50:  250nMAssay Description:Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50318326(4-(5-hexyl-2-oxooxazolidin-3-yl)benzonitrile | CHE...)
Affinity DataEC50:  760nMAssay Description:Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50318327(5-hexyl-3-(2-methoxyphenyl)oxazolidin-2-one | CHEM...)
Affinity DataEC50: >3.00E+3nMAssay Description:Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50318328(5-hexyl-3-(3-methoxyphenyl)oxazolidin-2-one | CHEM...)
Affinity DataEC50:  640nMAssay Description:Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50318329(5-hexyl-3-(4-methoxyphenyl)oxazolidin-2-one | CHEM...)
Affinity DataEC50:  1.17E+3nMAssay Description:Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50318330(5-hexyl-3-(2-hydroxyphenyl)oxazolidin-2-one | CHEM...)
Affinity DataEC50: >3.00E+3nMAssay Description:Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50318331(5-hexyl-3-(3-hydroxyphenyl)oxazolidin-2-one | CHEM...)
Affinity DataEC50:  1.93E+3nMAssay Description:Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50318332(5-hexyl-3-(4-hydroxyphenyl)oxazolidin-2-one | CHEM...)
Affinity DataEC50:  7.81E+3nMAssay Description:Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50318333(3-(2-aminophenyl)-5-hexyloxazolidin-2-one | CHEMBL...)
Affinity DataEC50: >3.00E+3nMAssay Description:Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50318334(3-(3-aminophenyl)-5-hexyloxazolidin-2-one | CHEMBL...)
Affinity DataEC50:  3.30E+3nMAssay Description:Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50318335(3-(4-aminophenyl)-5-hexyloxazolidin-2-one | CHEMBL...)
Affinity DataEC50:  5.87E+3nMAssay Description:Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50318336(CHEMBL1094125 | methyl 2-(5-hexyl-2-oxooxazolidin-...)
Affinity DataEC50: >3.00E+3nMAssay Description:Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50318337(CHEMBL1094461 | methyl 3-(5-hexyl-2-oxooxazolidin-...)
Affinity DataEC50:  1.35E+3nMAssay Description:Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50318338(CHEMBL1094462 | methyl 4-(5-hexyl-2-oxooxazolidin-...)
Affinity DataEC50:  1.22E+3nMAssay Description:Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50318339(5-hexyl-3-(2-(methylsulfonyl)phenyl)oxazolidin-2-o...)
Affinity DataEC50: >3.00E+3nMAssay Description:Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50318340(5-hexyl-3-(3-(methylsulfonyl)phenyl)oxazolidin-2-o...)
Affinity DataEC50:  2.70E+3nMAssay Description:Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50318341(5-hexyl-3-(4-(methylsulfonyl)phenyl)oxazolidin-2-o...)
Affinity DataEC50: >3.00E+4nMAssay Description:Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50318312((R)-5-hexyl-3-phenyloxazolidin-2-one | CHEMBL10947...)
Affinity DataEC50:  590nMAssay Description:Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50318342(5-octyl-3-phenyloxazolidin-2-one | CHEMBL1095701)
Affinity DataEC50:  1.20E+3nMAssay Description:Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50318343(5-pentyl-3-phenyloxazolidin-2-one | CHEMBL1095702)
Affinity DataEC50:  790nMAssay Description:Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50318344(5-butyl-3-phenyloxazolidin-2-one | CHEMBL1095703)
Affinity DataEC50:  1.30E+3nMAssay Description:Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50318345(5-benzyl-3-phenyloxazolidin-2-one | CHEMBL1095704)
Affinity DataEC50:  2.51E+4nMAssay Description:Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50318346(5-(phenoxymethyl)-3-phenyloxazolidin-2-one | CHEMB...)
Affinity DataEC50:  3.50E+3nMAssay Description:Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50318347(5-((4-chlorophenoxy)methyl)-3-phenyloxazolidin-2-o...)
Affinity DataEC50:  360nMAssay Description:Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50318348(3-phenyl-5-(o-tolyloxymethyl)oxazolidin-2-one | CH...)
Affinity DataEC50: >3.00E+4nMAssay Description:Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50318349(3-phenyl-5-(m-tolyloxymethyl)oxazolidin-2-one | CH...)
Affinity DataEC50:  3.44E+3nMAssay Description:Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50318350(3-phenyl-5-(p-tolyloxymethyl)oxazolidin-2-one | CH...)
Affinity DataEC50:  660nMAssay Description:Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50318351(5-((2-ethylphenoxy)methyl)-3-phenyloxazolidin-2-on...)
Affinity DataEC50: >3.00E+4nMAssay Description:Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50318352(5-((3-ethylphenoxy)methyl)-3-phenyloxazolidin-2-on...)
Affinity DataEC50:  360nMAssay Description:Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50318353(5-((4-ethylphenoxy)methyl)-3-phenyloxazolidin-2-on...)
Affinity DataEC50:  590nMAssay Description:Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50318354(5-((2-isopropylphenoxy)methyl)-3-phenyloxazolidin-...)
Affinity DataEC50: >3.00E+4nMAssay Description:Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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