Compile Data Set for Download or QSAR
maximum 50k data
Found 25 Enz. Inhib. hit(s) with all data for entry = 50032486
TargetCytochrome P450 3A4(Homo sapiens (Human))
Merck Research Lab.

Curated by ChEMBL
LigandPNGBDBM50330011(1-((3R,5R)-4-(4-chlorophenylsulfonyl)-5-isopropylm...)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of CYP3A4 after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Merck Research Lab.

Curated by ChEMBL
LigandPNGBDBM50330006(1-((3R,5R)-4-(4-chlorophenylsulfonyl)-5-isopropylm...)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of CYP3A4 after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Merck Research Lab.

Curated by ChEMBL
LigandPNGBDBM50330016(((3R,5R)-4-(4-chlorophenylsulfonyl)-5-(1-methylcyc...)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of CYP3A4 after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Merck Research Lab.

Curated by ChEMBL
LigandPNGBDBM50330017(1-((3R,5R)-4-(4-chlorophenylsulfonyl)-5-(cycloprop...)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of CYP3A4 after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Merck Research Lab.

Curated by ChEMBL
LigandPNGBDBM50330023(1-((3R,5R)-4-(4-chlorophenylsulfonyl)-5-(cycloprop...)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of CYP3A4 after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Merck Research Lab.

Curated by ChEMBL
LigandPNGBDBM50330015(((3R,5R)-4-(4-chlorophenylsulfonyl)-5-(1-methylcyc...)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of CYP3A4 after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Merck Research Lab.

Curated by ChEMBL
LigandPNGBDBM50330022((3S,5R)-1-((3R,5R)-4-(4-chlorophenylsulfonyl)-5-(c...)
Affinity DataIC50:  2nMAssay Description:Inhibition of CYP3A4 after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Merck Research Lab.

Curated by ChEMBL
LigandPNGBDBM50330018(1-((3R,5R)-4-(4-chlorophenylsulfonyl)-5-(cycloprop...)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of CYP3A4 after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Merck Research Lab.

Curated by ChEMBL
LigandPNGBDBM50330021(1-((3R,5R)-4-(4-chlorophenylsulfonyl)-5-(cycloprop...)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of CYP3A4 after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Merck Research Lab.

Curated by ChEMBL
LigandPNGBDBM50330014(((3R,5R)-4-(4-chlorophenylsulfonyl)-5-(1-methylcyc...)
Affinity DataIC50:  5.5nMAssay Description:Inhibition of CYP3A4 after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Merck Research Lab.

Curated by ChEMBL
LigandPNGBDBM50330010(1-((3R,5R)-4-(4-chlorophenylsulfonyl)-5-isopropylm...)
Affinity DataIC50:  6.40nMAssay Description:Inhibition of CYP3A4 after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Merck Research Lab.

Curated by ChEMBL
LigandPNGBDBM50330013(((3R,5R)-5-tert-butyl-4-(4-chlorophenylsulfonyl)mo...)
Affinity DataIC50:  7.10nMAssay Description:Inhibition of CYP3A4 after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Merck Research Lab.

Curated by ChEMBL
LigandPNGBDBM50330026(1-((3R,5R)-4-(4-chlorophenylsulfonyl)-5-(cycloprop...)
Affinity DataIC50:  11.3nMAssay Description:Inhibition of CYP3A4 after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Merck Research Lab.

Curated by ChEMBL
LigandPNGBDBM50330007((R)-1-((3R,5R)-4-(4-chlorophenylsulfonyl)-5-isopro...)
Affinity DataIC50:  13.6nMAssay Description:Inhibition of CYP3A4 after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Merck Research Lab.

Curated by ChEMBL
LigandPNGBDBM50330008(1-((3R,5R)-4-(4-chlorophenylsulfonyl)-5-isopropylm...)
Affinity DataIC50:  13.8nMAssay Description:Inhibition of CYP3A4 after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Merck Research Lab.

Curated by ChEMBL
LigandPNGBDBM50330012(((3R,5R)-5-tert-butyl-4-(4-chlorophenylsulfonyl)mo...)
Affinity DataIC50:  23.8nMAssay Description:Inhibition of CYP3A4 after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Merck Research Lab.

Curated by ChEMBL
LigandPNGBDBM50330024((2S,5R)-1-((3R,5R)-4-(4-chlorophenylsulfonyl)-5-(c...)
Affinity DataIC50: >30nMAssay Description:Inhibition of CYP3A4 after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Merck Research Lab.

Curated by ChEMBL
LigandPNGBDBM50330019(1-((3R,5R)-4-(4-chlorophenylsulfonyl)-5-(cycloprop...)
Affinity DataIC50: >30nMAssay Description:Inhibition of CYP3A4 after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Merck Research Lab.

Curated by ChEMBL
LigandPNGBDBM50330009((S)-1-((3R,5R)-4-(4-chlorophenylsulfonyl)-5-isopro...)
Affinity DataIC50:  30nMAssay Description:Inhibition of CYP3A4 after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Merck Research Lab.

Curated by ChEMBL
LigandPNGBDBM50330020(1-((3R,5R)-4-(4-chlorophenylsulfonyl)-5-(cycloprop...)
Affinity DataIC50: >30nMAssay Description:Inhibition of CYP3A4 after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Merck Research Lab.

Curated by ChEMBL
LigandPNGBDBM50330025(1-((3R,5R)-4-(4-chlorophenylsulfonyl)-5-(cycloprop...)
Affinity DataIC50: >30nMAssay Description:Inhibition of CYP3A4 after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Merck Research Lab.

Curated by ChEMBL
LigandPNGBDBM50330028(1-((3R,5R)-4-(4-chlorophenylsulfonyl)-5-(cycloprop...)
Affinity DataIC50: >30nMAssay Description:Inhibition of CYP3A4 after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Merck Research Lab.

Curated by ChEMBL
LigandPNGBDBM50330027(1-((3R,5R)-4-(4-chlorophenylsulfonyl)-5-(cycloprop...)
Affinity DataIC50:  30nMAssay Description:Inhibition of CYP3A4 after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Merck Research Lab.

Curated by ChEMBL
LigandPNGBDBM50220296(1-((2R,6S)-1-(4-chlorophenylsulfonyl)-6-cyclopropy...)
Affinity DataIC50:  400nMAssay Description:Inhibition of CYP3A4 after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Merck Research Lab.

Curated by ChEMBL
LigandPNGBDBM50223252(1-((2R,4S,6S)-1-(4-chlorophenylsulfonyl)-6-cyclopr...)
Affinity DataIC50:  1.95E+4nMAssay Description:Inhibition of CYP3A4 after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed