Compile Data Set for Download or QSAR
maximum 50k data
Found 71 Enz. Inhib. hit(s) with all data for entry = 50039060
LigandPNGBDBM50308135(1-(4-{[4-(Dimethylamino)piperidin-1-yl]carbonyl}ph...)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50308156(CHEMBL592615 | N-[2-(Dimethylamino)ethyl]-4-({[4-(...)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50378663(CHEMBL1204015)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50378662(CHEMBL1204014)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308156(CHEMBL592615 | N-[2-(Dimethylamino)ethyl]-4-({[4-(...)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50378663(CHEMBL1204015)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50308137(1-(4-(1,4'-bipiperidine-1'-carbonyl)phenyl)-3-(4-(...)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308137(1-(4-(1,4'-bipiperidine-1'-carbonyl)phenyl)-3-(4-(...)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308155(4-(3-(4-(4,6-Dimorpholino-1,3,5-triazin-2-yl)pheny...)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50308136(1-[4-(4,6-Dimorpholin-4-yl-1,3,5-triazin-2-yl)-phe...)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308136(1-[4-(4,6-Dimorpholin-4-yl-1,3,5-triazin-2-yl)-phe...)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50308147(1-[4-(4,6-Dimorpholin-4-yl-1,3,5-triazin-2-yl)-phe...)
Affinity DataIC50:  1nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308151(1-[4-(4,6-Dimorpholin-4-yl-1,3,5-triazin-2-yl)-phe...)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308150(1-[4-(4,6-Dimorpholin-4-yl-1,3,5-triazin-2-yl)-phe...)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50378662(CHEMBL1204014)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308154(4-[3-{4-(4,6-Dimorpholino-1,3,5-triazin-2yl)-pheny...)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50308148(1-[4-(4,6-Dimorpholin-4-yl-1,3,5-triazin-2-yl)-phe...)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50308155(4-(3-(4-(4,6-Dimorpholino-1,3,5-triazin-2-yl)pheny...)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308135(1-(4-{[4-(Dimethylamino)piperidin-1-yl]carbonyl}ph...)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50308150(1-[4-(4,6-Dimorpholin-4-yl-1,3,5-triazin-2-yl)-phe...)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308149(1-[4-(4,6-Dimorpholin-4-yl-1,3,5-triazin-2-yl)-phe...)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308148(1-[4-(4,6-Dimorpholin-4-yl-1,3,5-triazin-2-yl)-phe...)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308147(1-[4-(4,6-Dimorpholin-4-yl-1,3,5-triazin-2-yl)-phe...)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50308149(1-[4-(4,6-Dimorpholin-4-yl-1,3,5-triazin-2-yl)-phe...)
Affinity DataIC50:  2nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308152(1-[4-(4,6-Dimorpholin-4-yl-1,3,5-triazin-2-yl)-phe...)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308153(4-(3-(4-(4,6-Dimorpholino-1,3,5-triazin-2-yl)pheny...)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50308151(1-[4-(4,6-Dimorpholin-4-yl-1,3,5-triazin-2-yl)-phe...)
Affinity DataIC50:  3nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50308140(1-[4-(4,6-Dimorpholin-4-yl-1,3,5-triazin-2-yl)phen...)
Affinity DataIC50:  3nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308140(1-[4-(4,6-Dimorpholin-4-yl-1,3,5-triazin-2-yl)phen...)
Affinity DataIC50:  3.90nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308143(1-[4-(4,6-Dimorpholin-4-yl-1,3,5-triazin-2-yl)-phe...)
Affinity DataIC50:  3.90nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50308135(1-(4-{[4-(Dimethylamino)piperidin-1-yl]carbonyl}ph...)
Affinity DataIC50:  5.40nMAssay Description:Inhibition of PI3KgammaMore data for this Ligand-Target Pair
LigandPNGBDBM50308135(1-(4-{[4-(Dimethylamino)piperidin-1-yl]carbonyl}ph...)
Affinity DataIC50:  6nMAssay Description:Inhibition of PI3KbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50308135(1-(4-{[4-(Dimethylamino)piperidin-1-yl]carbonyl}ph...)
Affinity DataIC50:  6nMAssay Description:Inhibition of PI3KdeltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50308154(4-[3-{4-(4,6-Dimorpholino-1,3,5-triazin-2yl)-pheny...)
Affinity DataIC50:  6nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308144(1-[4-(4,6-Dimorpholin-4-yl-1,3,5-triazin-2-yl)-phe...)
Affinity DataIC50:  6.30nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50308143(1-[4-(4,6-Dimorpholin-4-yl-1,3,5-triazin-2-yl)-phe...)
Affinity DataIC50:  6.5nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308145(1-(4-Chlorophenyl)-3-[4-(4,6-dimorpholin-4-yl-1,3,...)
Affinity DataIC50:  6.70nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50308156(CHEMBL592615 | N-[2-(Dimethylamino)ethyl]-4-({[4-(...)
Affinity DataIC50:  8nMAssay Description:Inhibition of PI3KgammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50378663(CHEMBL1204015)
Affinity DataIC50:  9nMAssay Description:Inhibition of PI3KgammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50378662(CHEMBL1204014)
Affinity DataIC50:  9nMAssay Description:Inhibition of PI3KgammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308146((2,4-Difluorophenyl)-3-[4-(4,6-dimorpholin-4-yl-1,...)
Affinity DataIC50:  9.30nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50308136(1-[4-(4,6-Dimorpholin-4-yl-1,3,5-triazin-2-yl)-phe...)
Affinity DataIC50:  10nMAssay Description:Inhibition of PI3KgammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50308137(1-(4-(1,4'-bipiperidine-1'-carbonyl)phenyl)-3-(4-(...)
Affinity DataIC50:  10nMAssay Description:Inhibition of PI3KgammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308141(1-[4-(4,6-Dimorpholin-4-yl-1,3,5-triazin-2-yl)-phe...)
Affinity DataIC50:  10nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50308152(1-[4-(4,6-Dimorpholin-4-yl-1,3,5-triazin-2-yl)-phe...)
Affinity DataIC50:  11nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308142(1-(4-(4,6-dimorpholino-1,3,5-triazin-2-yl)phenyl)-...)
Affinity DataIC50:  11.3nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50308153(4-(3-(4-(4,6-Dimorpholino-1,3,5-triazin-2-yl)pheny...)
Affinity DataIC50:  12.5nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50308147(1-[4-(4,6-Dimorpholin-4-yl-1,3,5-triazin-2-yl)-phe...)
Affinity DataIC50:  14.5nMAssay Description:Inhibition of PI3KgammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50308144(1-[4-(4,6-Dimorpholin-4-yl-1,3,5-triazin-2-yl)-phe...)
Affinity DataIC50:  16.5nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50308145(1-(4-Chlorophenyl)-3-[4-(4,6-dimorpholin-4-yl-1,3,...)
Affinity DataIC50:  19.5nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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