Compile Data Set for Download or QSAR

Found 76 hits Enz. Inhib. hit(s) with all data for entry = 50039484   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50355198 (CHEMBL1835530) Show SMILES COc1ccc(NC(=S)n2cc(c(n2)-c2cccc(C)n2)-c2ccc3ncnn3c2)cc1 Show InChI InChI=1S/C23H19N7OS/c1-15-4-3-5-20(26-15)22-19(16-6-11-21-24-14-25-29(21)12-16)13-30(28-22)23(32)27-17-7-9-18(31-2)10-8-17/h3-14H,1-2H3,(H,27,32)	PDB MMDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.570	n/a	n/a	n/a	n/a	n/a	n/a
Ewha Womans University Curated by ChEMBL					Assay Description Inhibition of human recombinant GST-fused ALK5 expressed in Sf9 cells using casein as a substrate by radioisotopic protein kinase assay				Bioorg Med Chem Lett 21: 6049-53 (2011) Article DOI: 10.1016/j.bmcl.2011.08.064 BindingDB Entry DOI: 10.7270/Q2PG1SQZ
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50355189 (CHEMBL1835622) Show SMILES Cc1cccc(n1)-c1nn(cc1-c1ccc2ncnn2c1)C(=S)Nc1ccc(F)c(F)c1 Show InChI InChI=1S/C22H15F2N7S/c1-13-3-2-4-19(27-13)21-16(14-5-8-20-25-12-26-30(20)10-14)11-31(29-21)22(32)28-15-6-7-17(23)18(24)9-15/h2-12H,1H3,(H,28,32)	PDB MMDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.12	n/a	n/a	n/a	n/a	n/a	n/a
Ewha Womans University Curated by ChEMBL					Assay Description Inhibition of human recombinant GST-fused ALK5 expressed in Sf9 cells using casein as a substrate by radioisotopic protein kinase assay				Bioorg Med Chem Lett 21: 6049-53 (2011) Article DOI: 10.1016/j.bmcl.2011.08.064 BindingDB Entry DOI: 10.7270/Q2PG1SQZ
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50355206 (CHEMBL1835522) Show SMILES COc1cccc(NC(=S)n2cc(c(n2)-c2cccc(C)n2)-c2ccc3ncnn3c2)c1 Show InChI InChI=1S/C23H19N7OS/c1-15-5-3-8-20(26-15)22-19(16-9-10-21-24-14-25-29(21)12-16)13-30(28-22)23(32)27-17-6-4-7-18(11-17)31-2/h3-14H,1-2H3,(H,27,32)	PDB MMDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.26	n/a	n/a	n/a	n/a	n/a	n/a
Ewha Womans University Curated by ChEMBL					Assay Description Inhibition of human recombinant GST-fused ALK5 expressed in Sf9 cells using casein as a substrate by radioisotopic protein kinase assay				Bioorg Med Chem Lett 21: 6049-53 (2011) Article DOI: 10.1016/j.bmcl.2011.08.064 BindingDB Entry DOI: 10.7270/Q2PG1SQZ
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50355209 (CHEMBL1835519) Show SMILES Cc1cccc(n1)-c1nn(cc1-c1ccc2ncnn2c1)C(=S)Nc1cccc(Cl)c1 Show InChI InChI=1S/C22H16ClN7S/c1-14-4-2-7-19(26-14)21-18(15-8-9-20-24-13-25-29(20)11-15)12-30(28-21)22(31)27-17-6-3-5-16(23)10-17/h2-13H,1H3,(H,27,31)	PDB MMDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.37	n/a	n/a	n/a	n/a	n/a	n/a
Ewha Womans University Curated by ChEMBL					Assay Description Inhibition of human recombinant GST-fused ALK5 expressed in Sf9 cells using casein as a substrate by radioisotopic protein kinase assay				Bioorg Med Chem Lett 21: 6049-53 (2011) Article DOI: 10.1016/j.bmcl.2011.08.064 BindingDB Entry DOI: 10.7270/Q2PG1SQZ
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50355181 (CHEMBL1835630) Show SMILES COc1cc(NC(=S)n2cc(c(n2)-c2cccc(C)n2)-c2ccc3ncnn3c2)cc(OC)c1 Show InChI InChI=1S/C24H21N7O2S/c1-15-5-4-6-21(27-15)23-20(16-7-8-22-25-14-26-30(22)12-16)13-31(29-23)24(34)28-17-9-18(32-2)11-19(10-17)33-3/h4-14H,1-3H3,(H,28,34)	PDB MMDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.49	n/a	n/a	n/a	n/a	n/a	n/a
Ewha Womans University Curated by ChEMBL					Assay Description Inhibition of human recombinant GST-fused ALK5 expressed in Sf9 cells using casein as a substrate by radioisotopic protein kinase assay				Bioorg Med Chem Lett 21: 6049-53 (2011) Article DOI: 10.1016/j.bmcl.2011.08.064 BindingDB Entry DOI: 10.7270/Q2PG1SQZ
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50355175 (CHEMBL1835112) Show SMILES Cc1cccc(n1)-c1nn(cc1-c1ccc2ncnn2c1)C(=S)Nc1ccccc1 Show InChI InChI=1S/C22H17N7S/c1-15-6-5-9-19(25-15)21-18(16-10-11-20-23-14-24-28(20)12-16)13-29(27-21)22(30)26-17-7-3-2-4-8-17/h2-14H,1H3,(H,26,30)	PDB MMDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.82	n/a	n/a	n/a	n/a	n/a	n/a
Ewha Womans University Curated by ChEMBL					Assay Description Inhibition of human recombinant GST-fused ALK5 expressed in Sf9 cells using casein as a substrate by radioisotopic protein kinase assay				Bioorg Med Chem Lett 21: 6049-53 (2011) Article DOI: 10.1016/j.bmcl.2011.08.064 BindingDB Entry DOI: 10.7270/Q2PG1SQZ
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50355193 (CHEMBL1835535) Show SMILES Cc1cccc(n1)-c1nn(cc1-c1ccc2ncnn2c1)C(=S)Nc1ccccc1Cl Show InChI InChI=1S/C22H16ClN7S/c1-14-5-4-8-19(26-14)21-16(15-9-10-20-24-13-25-29(20)11-15)12-30(28-21)22(31)27-18-7-3-2-6-17(18)23/h2-13H,1H3,(H,27,31)	PDB MMDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.83	n/a	n/a	n/a	n/a	n/a	n/a
Ewha Womans University Curated by ChEMBL					Assay Description Inhibition of human recombinant GST-fused ALK5 expressed in Sf9 cells using casein as a substrate by radioisotopic protein kinase assay				Bioorg Med Chem Lett 21: 6049-53 (2011) Article DOI: 10.1016/j.bmcl.2011.08.064 BindingDB Entry DOI: 10.7270/Q2PG1SQZ
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50355196 (CHEMBL1835532) Show SMILES Cc1cccc(n1)-c1nn(cc1-c1ccc2ncnn2c1)C(=S)Nc1ccc(cc1)C#N Show InChI InChI=1S/C23H16N8S/c1-15-3-2-4-20(27-15)22-19(17-7-10-21-25-14-26-30(21)12-17)13-31(29-22)23(32)28-18-8-5-16(11-24)6-9-18/h2-10,12-14H,1H3,(H,28,32)	PDB MMDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.95	n/a	n/a	n/a	n/a	n/a	n/a
Ewha Womans University Curated by ChEMBL					Assay Description Inhibition of human recombinant GST-fused ALK5 expressed in Sf9 cells using casein as a substrate by radioisotopic protein kinase assay				Bioorg Med Chem Lett 21: 6049-53 (2011) Article DOI: 10.1016/j.bmcl.2011.08.064 BindingDB Entry DOI: 10.7270/Q2PG1SQZ
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50355207 (CHEMBL1835521) Show SMILES Cc1cccc(n1)-c1nn(cc1-c1ccc2ncnn2c1)C(=S)Nc1cccc(c1)C(F)(F)F Show InChI InChI=1S/C23H16F3N7S/c1-14-4-2-7-19(29-14)21-18(15-8-9-20-27-13-28-32(20)11-15)12-33(31-21)22(34)30-17-6-3-5-16(10-17)23(24,25)26/h2-13H,1H3,(H,30,34)	PDB MMDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.01	n/a	n/a	n/a	n/a	n/a	n/a
Ewha Womans University Curated by ChEMBL					Assay Description Inhibition of human recombinant GST-fused ALK5 expressed in Sf9 cells using casein as a substrate by radioisotopic protein kinase assay				Bioorg Med Chem Lett 21: 6049-53 (2011) Article DOI: 10.1016/j.bmcl.2011.08.064 BindingDB Entry DOI: 10.7270/Q2PG1SQZ
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50355199 (CHEMBL1835529) Show SMILES Cc1cccc(n1)-c1nn(cc1-c1ccc2ncnn2c1)C(=S)Nc1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C23H16F3N7S/c1-14-3-2-4-19(29-14)21-18(15-5-10-20-27-13-28-32(20)11-15)12-33(31-21)22(34)30-17-8-6-16(7-9-17)23(24,25)26/h2-13H,1H3,(H,30,34)	PDB MMDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.04	n/a	n/a	n/a	n/a	n/a	n/a
Ewha Womans University Curated by ChEMBL					Assay Description Inhibition of human recombinant GST-fused ALK5 expressed in Sf9 cells using casein as a substrate by radioisotopic protein kinase assay				Bioorg Med Chem Lett 21: 6049-53 (2011) Article DOI: 10.1016/j.bmcl.2011.08.064 BindingDB Entry DOI: 10.7270/Q2PG1SQZ
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50355188 (CHEMBL1835623) Show SMILES Cc1cccc(n1)-c1nn(cc1-c1ccc2ncnn2c1)C(=S)Nc1cc(F)cc(F)c1 Show InChI InChI=1S/C22H15F2N7S/c1-13-3-2-4-19(27-13)21-18(14-5-6-20-25-12-26-30(20)10-14)11-31(29-21)22(32)28-17-8-15(23)7-16(24)9-17/h2-12H,1H3,(H,28,32)	PDB MMDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.20	n/a	n/a	n/a	n/a	n/a	n/a
Ewha Womans University Curated by ChEMBL					Assay Description Inhibition of human recombinant GST-fused ALK5 expressed in Sf9 cells using casein as a substrate by radioisotopic protein kinase assay				Bioorg Med Chem Lett 21: 6049-53 (2011) Article DOI: 10.1016/j.bmcl.2011.08.064 BindingDB Entry DOI: 10.7270/Q2PG1SQZ
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50355197 (CHEMBL1835531) Show SMILES Cc1cccc(n1)-c1nn(cc1-c1ccc2ncnn2c1)C(=S)Nc1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C23H16F3N7OS/c1-14-3-2-4-19(29-14)21-18(15-5-10-20-27-13-28-32(20)11-15)12-33(31-21)22(35)30-16-6-8-17(9-7-16)34-23(24,25)26/h2-13H,1H3,(H,30,35)	PDB MMDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.30	n/a	n/a	n/a	n/a	n/a	n/a
Ewha Womans University Curated by ChEMBL					Assay Description Inhibition of human recombinant GST-fused ALK5 expressed in Sf9 cells using casein as a substrate by radioisotopic protein kinase assay				Bioorg Med Chem Lett 21: 6049-53 (2011) Article DOI: 10.1016/j.bmcl.2011.08.064 BindingDB Entry DOI: 10.7270/Q2PG1SQZ
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50355203 (CHEMBL1835525) Show SMILES Cc1cccc(n1)-c1nn(cc1-c1ccc2ncnn2c1)C(=S)Nc1cccc(c1)C(N)=O Show InChI InChI=1S/C23H18N8OS/c1-14-4-2-7-19(27-14)21-18(16-8-9-20-25-13-26-30(20)11-16)12-31(29-21)23(33)28-17-6-3-5-15(10-17)22(24)32/h2-13H,1H3,(H2,24,32)(H,28,33)	PDB MMDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.45	n/a	n/a	n/a	n/a	n/a	n/a
Ewha Womans University Curated by ChEMBL					Assay Description Inhibition of human recombinant GST-fused ALK5 expressed in Sf9 cells using casein as a substrate by radioisotopic protein kinase assay				Bioorg Med Chem Lett 21: 6049-53 (2011) Article DOI: 10.1016/j.bmcl.2011.08.064 BindingDB Entry DOI: 10.7270/Q2PG1SQZ
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50355185 (CHEMBL1835626) Show SMILES Cc1cccc(n1)-c1nn(cc1-c1ccc2ncnn2c1)C(=S)Nc1ccc(C)c(C)c1 Show InChI InChI=1S/C24H21N7S/c1-15-7-9-19(11-16(15)2)28-24(32)31-13-20(18-8-10-22-25-14-26-30(22)12-18)23(29-31)21-6-4-5-17(3)27-21/h4-14H,1-3H3,(H,28,32)	PDB MMDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.54	n/a	n/a	n/a	n/a	n/a	n/a
Ewha Womans University Curated by ChEMBL					Assay Description Inhibition of human recombinant GST-fused ALK5 expressed in Sf9 cells using casein as a substrate by radioisotopic protein kinase assay				Bioorg Med Chem Lett 21: 6049-53 (2011) Article DOI: 10.1016/j.bmcl.2011.08.064 BindingDB Entry DOI: 10.7270/Q2PG1SQZ
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50355187 (CHEMBL1835624) Show SMILES Cc1cccc(n1)-c1nn(cc1-c1ccc2ncnn2c1)C(=S)Nc1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C22H15Cl2N7S/c1-13-3-2-4-19(27-13)21-16(14-5-8-20-25-12-26-30(20)10-14)11-31(29-21)22(32)28-15-6-7-17(23)18(24)9-15/h2-12H,1H3,(H,28,32)	PDB MMDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.78	n/a	n/a	n/a	n/a	n/a	n/a
Ewha Womans University Curated by ChEMBL					Assay Description Inhibition of human recombinant GST-fused ALK5 expressed in Sf9 cells using casein as a substrate by radioisotopic protein kinase assay				Bioorg Med Chem Lett 21: 6049-53 (2011) Article DOI: 10.1016/j.bmcl.2011.08.064 BindingDB Entry DOI: 10.7270/Q2PG1SQZ
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50355201 (CHEMBL1835527) Show SMILES Cc1cccc(n1)-c1nn(cc1-c1ccc2ncnn2c1)C(=S)Nc1ccc(Cl)cc1 Show InChI InChI=1S/C22H16ClN7S/c1-14-3-2-4-19(26-14)21-18(15-5-10-20-24-13-25-29(20)11-15)12-30(28-21)22(31)27-17-8-6-16(23)7-9-17/h2-13H,1H3,(H,27,31)	PDB MMDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.87	n/a	n/a	n/a	n/a	n/a	n/a
Ewha Womans University Curated by ChEMBL					Assay Description Inhibition of human recombinant GST-fused ALK5 expressed in Sf9 cells using casein as a substrate by radioisotopic protein kinase assay				Bioorg Med Chem Lett 21: 6049-53 (2011) Article DOI: 10.1016/j.bmcl.2011.08.064 BindingDB Entry DOI: 10.7270/Q2PG1SQZ
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50355184 (CHEMBL1835627) Show SMILES Cc1cc(C)cc(NC(=S)n2cc(c(n2)-c2cccc(C)n2)-c2ccc3ncnn3c2)c1 Show InChI InChI=1S/C24H21N7S/c1-15-9-16(2)11-19(10-15)28-24(32)31-13-20(18-7-8-22-25-14-26-30(22)12-18)23(29-31)21-6-4-5-17(3)27-21/h4-14H,1-3H3,(H,28,32)	PDB MMDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.97	n/a	n/a	n/a	n/a	n/a	n/a
Ewha Womans University Curated by ChEMBL					Assay Description Inhibition of human recombinant GST-fused ALK5 expressed in Sf9 cells using casein as a substrate by radioisotopic protein kinase assay				Bioorg Med Chem Lett 21: 6049-53 (2011) Article DOI: 10.1016/j.bmcl.2011.08.064 BindingDB Entry DOI: 10.7270/Q2PG1SQZ
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50355208 (CHEMBL1835520) Show SMILES Cc1cccc(NC(=S)n2cc(c(n2)-c2cccc(C)n2)-c2ccc3ncnn3c2)c1 Show InChI InChI=1S/C23H19N7S/c1-15-5-3-7-18(11-15)27-23(31)30-13-19(17-9-10-21-24-14-25-29(21)12-17)22(28-30)20-8-4-6-16(2)26-20/h3-14H,1-2H3,(H,27,31)	PDB MMDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.98	n/a	n/a	n/a	n/a	n/a	n/a
Ewha Womans University Curated by ChEMBL					Assay Description Inhibition of human recombinant GST-fused ALK5 expressed in Sf9 cells using casein as a substrate by radioisotopic protein kinase assay				Bioorg Med Chem Lett 21: 6049-53 (2011) Article DOI: 10.1016/j.bmcl.2011.08.064 BindingDB Entry DOI: 10.7270/Q2PG1SQZ
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50355190 (CHEMBL1835621) Show SMILES Cc1cccc(n1)-c1nn(cc1-c1ccc2ncnn2c1)C(=S)Nc1ccccc1OC(F)(F)F Show InChI InChI=1S/C23H16F3N7OS/c1-14-5-4-7-18(29-14)21-16(15-9-10-20-27-13-28-32(20)11-15)12-33(31-21)22(35)30-17-6-2-3-8-19(17)34-23(24,25)26/h2-13H,1H3,(H,30,35)	PDB MMDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.98	n/a	n/a	n/a	n/a	n/a	n/a
Ewha Womans University Curated by ChEMBL					Assay Description Inhibition of human recombinant GST-fused ALK5 expressed in Sf9 cells using casein as a substrate by radioisotopic protein kinase assay				Bioorg Med Chem Lett 21: 6049-53 (2011) Article DOI: 10.1016/j.bmcl.2011.08.064 BindingDB Entry DOI: 10.7270/Q2PG1SQZ
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50355192 (CHEMBL1835536) Show SMILES Cc1cccc(n1)-c1nn(cc1-c1ccc2ncnn2c1)C(=S)Nc1ccccc1C Show InChI InChI=1S/C23H19N7S/c1-15-6-3-4-8-19(15)27-23(31)30-13-18(17-10-11-21-24-14-25-29(21)12-17)22(28-30)20-9-5-7-16(2)26-20/h3-14H,1-2H3,(H,27,31)	PDB MMDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Ewha Womans University Curated by ChEMBL					Assay Description Inhibition of human recombinant GST-fused ALK5 expressed in Sf9 cells using casein as a substrate by radioisotopic protein kinase assay				Bioorg Med Chem Lett 21: 6049-53 (2011) Article DOI: 10.1016/j.bmcl.2011.08.064 BindingDB Entry DOI: 10.7270/Q2PG1SQZ
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50355202 (CHEMBL1835526) Show SMILES Cc1cccc(n1)-c1nn(cc1-c1ccc2ncnn2c1)C(=S)Nc1ccc(F)cc1 Show InChI InChI=1S/C22H16FN7S/c1-14-3-2-4-19(26-14)21-18(15-5-10-20-24-13-25-29(20)11-15)12-30(28-21)22(31)27-17-8-6-16(23)7-9-17/h2-13H,1H3,(H,27,31)	PDB MMDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.09	n/a	n/a	n/a	n/a	n/a	n/a
Ewha Womans University Curated by ChEMBL					Assay Description Inhibition of human recombinant GST-fused ALK5 expressed in Sf9 cells using casein as a substrate by radioisotopic protein kinase assay				Bioorg Med Chem Lett 21: 6049-53 (2011) Article DOI: 10.1016/j.bmcl.2011.08.064 BindingDB Entry DOI: 10.7270/Q2PG1SQZ
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50355183 (CHEMBL1835628) Show SMILES Cc1cccc(n1)-c1nn(cc1-c1ccc2ncnn2c1)C(=S)Nc1cc(cc(c1)C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C24H15F6N7S/c1-13-3-2-4-19(33-13)21-18(14-5-6-20-31-12-32-36(20)10-14)11-37(35-21)22(38)34-17-8-15(23(25,26)27)7-16(9-17)24(28,29)30/h2-12H,1H3,(H,34,38)	PDB MMDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.12	n/a	n/a	n/a	n/a	n/a	n/a
Ewha Womans University Curated by ChEMBL					Assay Description Inhibition of human recombinant GST-fused ALK5 expressed in Sf9 cells using casein as a substrate by radioisotopic protein kinase assay				Bioorg Med Chem Lett 21: 6049-53 (2011) Article DOI: 10.1016/j.bmcl.2011.08.064 BindingDB Entry DOI: 10.7270/Q2PG1SQZ
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50355182 (CHEMBL1835629) Show SMILES COc1ccc(NC(=S)n2cc(c(n2)-c2cccc(C)n2)-c2ccc3ncnn3c2)cc1OC Show InChI InChI=1S/C24H21N7O2S/c1-15-5-4-6-19(27-15)23-18(16-7-10-22-25-14-26-30(22)12-16)13-31(29-23)24(34)28-17-8-9-20(32-2)21(11-17)33-3/h4-14H,1-3H3,(H,28,34)	PDB MMDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.37	n/a	n/a	n/a	n/a	n/a	n/a
Ewha Womans University Curated by ChEMBL					Assay Description Inhibition of human recombinant GST-fused ALK5 expressed in Sf9 cells using casein as a substrate by radioisotopic protein kinase assay				Bioorg Med Chem Lett 21: 6049-53 (2011) Article DOI: 10.1016/j.bmcl.2011.08.064 BindingDB Entry DOI: 10.7270/Q2PG1SQZ
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50355174 (CHEMBL1835518) Show SMILES Cc1cccc(n1)-c1nn(cc1-c1ccc2ncnn2c1)C(=S)Nc1cccc(F)c1 Show InChI InChI=1S/C22H16FN7S/c1-14-4-2-7-19(26-14)21-18(15-8-9-20-24-13-25-29(20)11-15)12-30(28-21)22(31)27-17-6-3-5-16(23)10-17/h2-13H,1H3,(H,27,31)	PDB MMDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.43	n/a	n/a	n/a	n/a	n/a	n/a
Ewha Womans University Curated by ChEMBL					Assay Description Inhibition of human recombinant GST-fused ALK5 expressed in Sf9 cells using casein as a substrate by radioisotopic protein kinase assay				Bioorg Med Chem Lett 21: 6049-53 (2011) Article DOI: 10.1016/j.bmcl.2011.08.064 BindingDB Entry DOI: 10.7270/Q2PG1SQZ
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50355204 (CHEMBL1835524) Show SMILES Cc1cccc(n1)-c1nn(cc1-c1ccc2ncnn2c1)C(=S)Nc1cccc(c1)C#N Show InChI InChI=1S/C23H16N8S/c1-15-4-2-7-20(27-15)22-19(17-8-9-21-25-14-26-30(21)12-17)13-31(29-22)23(32)28-18-6-3-5-16(10-18)11-24/h2-10,12-14H,1H3,(H,28,32)	PDB MMDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.5	n/a	n/a	n/a	n/a	n/a	n/a
Ewha Womans University Curated by ChEMBL					Assay Description Inhibition of human recombinant GST-fused ALK5 expressed in Sf9 cells using casein as a substrate by radioisotopic protein kinase assay				Bioorg Med Chem Lett 21: 6049-53 (2011) Article DOI: 10.1016/j.bmcl.2011.08.064 BindingDB Entry DOI: 10.7270/Q2PG1SQZ
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50355186 (CHEMBL1835625) Show SMILES Cc1cccc(n1)-c1nn(cc1-c1ccc2ncnn2c1)C(=S)Nc1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C22H15Cl2N7S/c1-13-3-2-4-19(27-13)21-18(14-5-6-20-25-12-26-30(20)10-14)11-31(29-21)22(32)28-17-8-15(23)7-16(24)9-17/h2-12H,1H3,(H,28,32)	PDB MMDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.08	n/a	n/a	n/a	n/a	n/a	n/a
Ewha Womans University Curated by ChEMBL					Assay Description Inhibition of human recombinant GST-fused ALK5 expressed in Sf9 cells using casein as a substrate by radioisotopic protein kinase assay				Bioorg Med Chem Lett 21: 6049-53 (2011) Article DOI: 10.1016/j.bmcl.2011.08.064 BindingDB Entry DOI: 10.7270/Q2PG1SQZ
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50355194 (CHEMBL1835534) Show SMILES Cc1cccc(n1)-c1nn(cc1-c1ccc2ncnn2c1)C(=S)Nc1ccccc1F Show InChI InChI=1S/C22H16FN7S/c1-14-5-4-8-19(26-14)21-16(15-9-10-20-24-13-25-29(20)11-15)12-30(28-21)22(31)27-18-7-3-2-6-17(18)23/h2-13H,1H3,(H,27,31)	PDB MMDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.39	n/a	n/a	n/a	n/a	n/a	n/a
Ewha Womans University Curated by ChEMBL					Assay Description Inhibition of human recombinant GST-fused ALK5 expressed in Sf9 cells using casein as a substrate by radioisotopic protein kinase assay				Bioorg Med Chem Lett 21: 6049-53 (2011) Article DOI: 10.1016/j.bmcl.2011.08.064 BindingDB Entry DOI: 10.7270/Q2PG1SQZ
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50355191 (CHEMBL1835620) Show SMILES COc1ccccc1NC(=S)n1cc(c(n1)-c1cccc(C)n1)-c1ccc2ncnn2c1 Show InChI InChI=1S/C23H19N7OS/c1-15-6-5-8-19(26-15)22-17(16-10-11-21-24-14-25-29(21)12-16)13-30(28-22)23(32)27-18-7-3-4-9-20(18)31-2/h3-14H,1-2H3,(H,27,32)	PDB MMDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.69	n/a	n/a	n/a	n/a	n/a	n/a
Ewha Womans University Curated by ChEMBL					Assay Description Inhibition of human recombinant GST-fused ALK5 expressed in Sf9 cells using casein as a substrate by radioisotopic protein kinase assay				Bioorg Med Chem Lett 21: 6049-53 (2011) Article DOI: 10.1016/j.bmcl.2011.08.064 BindingDB Entry DOI: 10.7270/Q2PG1SQZ
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50355200 (CHEMBL1835528) Show SMILES Cc1ccc(NC(=S)n2cc(c(n2)-c2cccc(C)n2)-c2ccc3ncnn3c2)cc1 Show InChI InChI=1S/C23H19N7S/c1-15-6-9-18(10-7-15)27-23(31)30-13-19(17-8-11-21-24-14-25-29(21)12-17)22(28-30)20-5-3-4-16(2)26-20/h3-14H,1-2H3,(H,27,31)	PDB MMDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.61	n/a	n/a	n/a	n/a	n/a	n/a
Ewha Womans University Curated by ChEMBL					Assay Description Inhibition of human recombinant GST-fused ALK5 expressed in Sf9 cells using casein as a substrate by radioisotopic protein kinase assay				Bioorg Med Chem Lett 21: 6049-53 (2011) Article DOI: 10.1016/j.bmcl.2011.08.064 BindingDB Entry DOI: 10.7270/Q2PG1SQZ
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50355205 (CHEMBL1835523) Show SMILES Cc1cccc(n1)-c1nn(cc1-c1ccc2ncnn2c1)C(=S)Nc1cccc(OC(F)(F)F)c1 Show InChI InChI=1S/C23H16F3N7OS/c1-14-4-2-7-19(29-14)21-18(15-8-9-20-27-13-28-32(20)11-15)12-33(31-21)22(35)30-16-5-3-6-17(10-16)34-23(24,25)26/h2-13H,1H3,(H,30,35)	PDB MMDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Ewha Womans University Curated by ChEMBL					Assay Description Inhibition of human recombinant GST-fused ALK5 expressed in Sf9 cells using casein as a substrate by radioisotopic protein kinase assay				Bioorg Med Chem Lett 21: 6049-53 (2011) Article DOI: 10.1016/j.bmcl.2011.08.064 BindingDB Entry DOI: 10.7270/Q2PG1SQZ
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50355195 (CHEMBL1835533) Show SMILES Cc1cccc(n1)-c1nn(cc1-c1ccc2ncnn2c1)C(=S)Nc1ccc(cc1)C(N)=O Show InChI InChI=1S/C23H18N8OS/c1-14-3-2-4-19(27-14)21-18(16-7-10-20-25-13-26-30(20)11-16)12-31(29-21)23(33)28-17-8-5-15(6-9-17)22(24)32/h2-13H,1H3,(H2,24,32)(H,28,33)	PDB MMDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15.6	n/a	n/a	n/a	n/a	n/a	n/a
Ewha Womans University Curated by ChEMBL					Assay Description Inhibition of human recombinant GST-fused ALK5 expressed in Sf9 cells using casein as a substrate by radioisotopic protein kinase assay				Bioorg Med Chem Lett 21: 6049-53 (2011) Article DOI: 10.1016/j.bmcl.2011.08.064 BindingDB Entry DOI: 10.7270/Q2PG1SQZ
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50252542 (3-((5-(6-methylpyridin-2-yl)-4-(quinoxalin-6-yl)-1...) Show SMILES Cc1cccc(n1)-c1nc(Cc2cccc(c2)C(N)=O)[nH]c1-c1ccc2nccnc2c1 Show InChI InChI=1S/C25H20N6O/c1-15-4-2-7-20(29-15)24-23(17-8-9-19-21(14-17)28-11-10-27-19)30-22(31-24)13-16-5-3-6-18(12-16)25(26)32/h2-12,14H,13H2,1H3,(H2,26,32)(H,30,31)	PDB MMDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	17.2	n/a	n/a	n/a	n/a	n/a	n/a
Ewha Womans University Curated by ChEMBL					Assay Description Inhibition of human recombinant GST-fused ALK5 expressed in Sf9 cells using casein as a substrate by radioisotopic protein kinase assay				Bioorg Med Chem Lett 21: 6049-53 (2011) Article DOI: 10.1016/j.bmcl.2011.08.064 BindingDB Entry DOI: 10.7270/Q2PG1SQZ
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50355180 (CHEMBL1835709) Show SMILES CN1CCC(CC1)NC(=S)n1cc(c(n1)-c1cccc(C)n1)-c1ccc2ncnn2c1 Show InChI InChI=1S/C22H24N8S/c1-15-4-3-5-19(25-15)21-18(16-6-7-20-23-14-24-29(20)12-16)13-30(27-21)22(31)26-17-8-10-28(2)11-9-17/h3-7,12-14,17H,8-11H2,1-2H3,(H,26,31)	PDB MMDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	39.5	n/a	n/a	n/a	n/a	n/a	n/a
Ewha Womans University Curated by ChEMBL					Assay Description Inhibition of human recombinant GST-fused ALK5 expressed in Sf9 cells using casein as a substrate by radioisotopic protein kinase assay				Bioorg Med Chem Lett 21: 6049-53 (2011) Article DOI: 10.1016/j.bmcl.2011.08.064 BindingDB Entry DOI: 10.7270/Q2PG1SQZ
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50298220 (2-(4-(benzo[d][1,3]dioxol-5-yl)-2-tert-butyl-1H-im...) Show SMILES Cc1cccc(n1)-c1nc([nH]c1-c1ccc2OCOc2c1)C(C)(C)C Show InChI InChI=1S/C20H21N3O2/c1-12-6-5-7-14(21-12)18-17(22-19(23-18)20(2,3)4)13-8-9-15-16(10-13)25-11-24-15/h5-10H,11H2,1-4H3,(H,22,23)	PDB MMDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	54.4	n/a	n/a	n/a	n/a	n/a	n/a
Ewha Womans University Curated by ChEMBL					Assay Description Inhibition of human recombinant GST-fused ALK5 expressed in Sf9 cells using casein as a substrate by radioisotopic protein kinase assay				Bioorg Med Chem Lett 21: 6049-53 (2011) Article DOI: 10.1016/j.bmcl.2011.08.064 BindingDB Entry DOI: 10.7270/Q2PG1SQZ
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50355176 (CHEMBL1835713) Show SMILES Cc1nc2ccc(cn2n1)-c1cn(nc1-c1cccc(C)n1)C(=S)Nc1cccc(c1)C(N)=O Show InChI InChI=1S/C24H20N8OS/c1-14-5-3-8-20(26-14)22-19(17-9-10-21-27-15(2)29-31(21)12-17)13-32(30-22)24(34)28-18-7-4-6-16(11-18)23(25)33/h3-13H,1-2H3,(H2,25,33)(H,28,34)	PDB MMDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	66.8	n/a	n/a	n/a	n/a	n/a	n/a
Ewha Womans University Curated by ChEMBL					Assay Description Inhibition of human recombinant GST-fused ALK5 expressed in Sf9 cells using casein as a substrate by radioisotopic protein kinase assay				Bioorg Med Chem Lett 21: 6049-53 (2011) Article DOI: 10.1016/j.bmcl.2011.08.064 BindingDB Entry DOI: 10.7270/Q2PG1SQZ
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50355177 (CHEMBL1835712) Show SMILES Cc1nc2ccc(cn2n1)-c1cn(nc1-c1cccc(C)n1)C(=S)Nc1cccc(c1)C#N Show InChI InChI=1S/C24H18N8S/c1-15-5-3-8-21(26-15)23-20(18-9-10-22-27-16(2)29-31(22)13-18)14-32(30-23)24(33)28-19-7-4-6-17(11-19)12-25/h3-11,13-14H,1-2H3,(H,28,33)	PDB MMDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	85.3	n/a	n/a	n/a	n/a	n/a	n/a
Ewha Womans University Curated by ChEMBL					Assay Description Inhibition of human recombinant GST-fused ALK5 expressed in Sf9 cells using casein as a substrate by radioisotopic protein kinase assay				Bioorg Med Chem Lett 21: 6049-53 (2011) Article DOI: 10.1016/j.bmcl.2011.08.064 BindingDB Entry DOI: 10.7270/Q2PG1SQZ
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50355179 (CHEMBL1835710) Show SMILES Cc1cccc(n1)-c1nn(cc1-c1ccc2ncnn2c1)C(=S)NC1CCN(Cc2ccccc2)CC1 Show InChI InChI=1S/C28H28N8S/c1-20-6-5-9-25(31-20)27-24(22-10-11-26-29-19-30-35(26)17-22)18-36(33-27)28(37)32-23-12-14-34(15-13-23)16-21-7-3-2-4-8-21/h2-11,17-19,23H,12-16H2,1H3,(H,32,37)	PDB MMDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	95.7	n/a	n/a	n/a	n/a	n/a	n/a
Ewha Womans University Curated by ChEMBL					Assay Description Inhibition of human recombinant GST-fused ALK5 expressed in Sf9 cells using casein as a substrate by radioisotopic protein kinase assay				Bioorg Med Chem Lett 21: 6049-53 (2011) Article DOI: 10.1016/j.bmcl.2011.08.064 BindingDB Entry DOI: 10.7270/Q2PG1SQZ
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50355178 (CHEMBL1835711) Show SMILES Cc1nc2ccc(cn2n1)-c1cn(nc1-c1cccc(C)n1)C(=S)Nc1ccccc1 Show InChI InChI=1S/C23H19N7S/c1-15-7-6-10-20(24-15)22-19(17-11-12-21-25-16(2)27-29(21)13-17)14-30(28-22)23(31)26-18-8-4-3-5-9-18/h3-14H,1-2H3,(H,26,31)	PDB MMDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	102	n/a	n/a	n/a	n/a	n/a	n/a
Ewha Womans University Curated by ChEMBL					Assay Description Inhibition of human recombinant GST-fused ALK5 expressed in Sf9 cells using casein as a substrate by radioisotopic protein kinase assay				Bioorg Med Chem Lett 21: 6049-53 (2011) Article DOI: 10.1016/j.bmcl.2011.08.064 BindingDB Entry DOI: 10.7270/Q2PG1SQZ
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50252542 (3-((5-(6-methylpyridin-2-yl)-4-(quinoxalin-6-yl)-1...) Show SMILES Cc1cccc(n1)-c1nc(Cc2cccc(c2)C(N)=O)[nH]c1-c1ccc2nccnc2c1 Show InChI InChI=1S/C25H20N6O/c1-15-4-2-7-20(29-15)24-23(17-8-9-19-21(14-17)28-11-10-27-19)30-22(31-24)13-16-5-3-6-18(12-16)25(26)32/h2-12,14H,13H2,1H3,(H2,26,32)(H,30,31)	PDB MMDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	480	n/a	n/a	n/a	n/a	n/a	n/a
Ewha Womans University Curated by ChEMBL					Assay Description Inhibition of human recombinant p38alpha expressed in Escherichia coli using ATF2 as a substrate by radioisotopic protein kinase assay				Bioorg Med Chem Lett 21: 6049-53 (2011) Article DOI: 10.1016/j.bmcl.2011.08.064 BindingDB Entry DOI: 10.7270/Q2PG1SQZ
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50355180 (CHEMBL1835709) Show SMILES CN1CCC(CC1)NC(=S)n1cc(c(n1)-c1cccc(C)n1)-c1ccc2ncnn2c1 Show InChI InChI=1S/C22H24N8S/c1-15-4-3-5-19(25-15)21-18(16-6-7-20-23-14-24-29(20)12-16)13-30(27-21)22(31)26-17-8-10-28(2)11-9-17/h3-7,12-14,17H,8-11H2,1-2H3,(H,26,31)	PDB MMDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	496	n/a	n/a	n/a	n/a	n/a	n/a
Ewha Womans University Curated by ChEMBL					Assay Description Inhibition of human recombinant p38alpha expressed in Escherichia coli using ATF2 as a substrate by radioisotopic protein kinase assay				Bioorg Med Chem Lett 21: 6049-53 (2011) Article DOI: 10.1016/j.bmcl.2011.08.064 BindingDB Entry DOI: 10.7270/Q2PG1SQZ
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50298220 (2-(4-(benzo[d][1,3]dioxol-5-yl)-2-tert-butyl-1H-im...) Show SMILES Cc1cccc(n1)-c1nc([nH]c1-c1ccc2OCOc2c1)C(C)(C)C Show InChI InChI=1S/C20H21N3O2/c1-12-6-5-7-14(21-12)18-17(22-19(23-18)20(2,3)4)13-8-9-15-16(10-13)25-11-24-15/h5-10H,11H2,1-4H3,(H,22,23)	PDB MMDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	594	n/a	n/a	n/a	n/a	n/a	n/a
Ewha Womans University Curated by ChEMBL					Assay Description Inhibition of human recombinant p38alpha expressed in Escherichia coli using ATF2 as a substrate by radioisotopic protein kinase assay				Bioorg Med Chem Lett 21: 6049-53 (2011) Article DOI: 10.1016/j.bmcl.2011.08.064 BindingDB Entry DOI: 10.7270/Q2PG1SQZ
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50355179 (CHEMBL1835710) Show SMILES Cc1cccc(n1)-c1nn(cc1-c1ccc2ncnn2c1)C(=S)NC1CCN(Cc2ccccc2)CC1 Show InChI InChI=1S/C28H28N8S/c1-20-6-5-9-25(31-20)27-24(22-10-11-26-29-19-30-35(26)17-22)18-36(33-27)28(37)32-23-12-14-34(15-13-23)16-21-7-3-2-4-8-21/h2-11,17-19,23H,12-16H2,1H3,(H,32,37)	PDB MMDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	598	n/a	n/a	n/a	n/a	n/a	n/a
Ewha Womans University Curated by ChEMBL					Assay Description Inhibition of human recombinant p38alpha expressed in Escherichia coli using ATF2 as a substrate by radioisotopic protein kinase assay				Bioorg Med Chem Lett 21: 6049-53 (2011) Article DOI: 10.1016/j.bmcl.2011.08.064 BindingDB Entry DOI: 10.7270/Q2PG1SQZ
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50355189 (CHEMBL1835622) Show SMILES Cc1cccc(n1)-c1nn(cc1-c1ccc2ncnn2c1)C(=S)Nc1ccc(F)c(F)c1 Show InChI InChI=1S/C22H15F2N7S/c1-13-3-2-4-19(27-13)21-16(14-5-8-20-25-12-26-30(20)10-14)11-31(29-21)22(32)28-15-6-7-17(23)18(24)9-15/h2-12H,1H3,(H,28,32)	PDB MMDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.45E+3	n/a	n/a	n/a	n/a	n/a	n/a
Ewha Womans University Curated by ChEMBL					Assay Description Inhibition of human recombinant p38alpha expressed in Escherichia coli using ATF2 as a substrate by radioisotopic protein kinase assay				Bioorg Med Chem Lett 21: 6049-53 (2011) Article DOI: 10.1016/j.bmcl.2011.08.064 BindingDB Entry DOI: 10.7270/Q2PG1SQZ
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50355187 (CHEMBL1835624) Show SMILES Cc1cccc(n1)-c1nn(cc1-c1ccc2ncnn2c1)C(=S)Nc1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C22H15Cl2N7S/c1-13-3-2-4-19(27-13)21-16(14-5-8-20-25-12-26-30(20)10-14)11-31(29-21)22(32)28-15-6-7-17(23)18(24)9-15/h2-12H,1H3,(H,28,32)	PDB MMDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.69E+3	n/a	n/a	n/a	n/a	n/a	n/a
Ewha Womans University Curated by ChEMBL					Assay Description Inhibition of human recombinant p38alpha expressed in Escherichia coli using ATF2 as a substrate by radioisotopic protein kinase assay				Bioorg Med Chem Lett 21: 6049-53 (2011) Article DOI: 10.1016/j.bmcl.2011.08.064 BindingDB Entry DOI: 10.7270/Q2PG1SQZ
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50355207 (CHEMBL1835521) Show SMILES Cc1cccc(n1)-c1nn(cc1-c1ccc2ncnn2c1)C(=S)Nc1cccc(c1)C(F)(F)F Show InChI InChI=1S/C23H16F3N7S/c1-14-4-2-7-19(29-14)21-18(15-8-9-20-27-13-28-32(20)11-15)12-33(31-21)22(34)30-17-6-3-5-16(10-17)23(24,25)26/h2-13H,1H3,(H,30,34)	PDB MMDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.98E+3	n/a	n/a	n/a	n/a	n/a	n/a
Ewha Womans University Curated by ChEMBL					Assay Description Inhibition of human recombinant p38alpha expressed in Escherichia coli using ATF2 as a substrate by radioisotopic protein kinase assay				Bioorg Med Chem Lett 21: 6049-53 (2011) Article DOI: 10.1016/j.bmcl.2011.08.064 BindingDB Entry DOI: 10.7270/Q2PG1SQZ
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50355181 (CHEMBL1835630) Show SMILES COc1cc(NC(=S)n2cc(c(n2)-c2cccc(C)n2)-c2ccc3ncnn3c2)cc(OC)c1 Show InChI InChI=1S/C24H21N7O2S/c1-15-5-4-6-21(27-15)23-20(16-7-8-22-25-14-26-30(22)12-16)13-31(29-23)24(34)28-17-9-18(32-2)11-19(10-17)33-3/h4-14H,1-3H3,(H,28,34)	PDB MMDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.46E+3	n/a	n/a	n/a	n/a	n/a	n/a
Ewha Womans University Curated by ChEMBL					Assay Description Inhibition of human recombinant p38alpha expressed in Escherichia coli using ATF2 as a substrate by radioisotopic protein kinase assay				Bioorg Med Chem Lett 21: 6049-53 (2011) Article DOI: 10.1016/j.bmcl.2011.08.064 BindingDB Entry DOI: 10.7270/Q2PG1SQZ
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50355175 (CHEMBL1835112) Show SMILES Cc1cccc(n1)-c1nn(cc1-c1ccc2ncnn2c1)C(=S)Nc1ccccc1 Show InChI InChI=1S/C22H17N7S/c1-15-6-5-9-19(25-15)21-18(16-10-11-20-23-14-24-28(20)12-16)13-29(27-21)22(30)26-17-7-3-2-4-8-17/h2-14H,1H3,(H,26,30)	PDB MMDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Ewha Womans University Curated by ChEMBL					Assay Description Inhibition of human recombinant p38alpha expressed in Escherichia coli using ATF2 as a substrate by radioisotopic protein kinase assay				Bioorg Med Chem Lett 21: 6049-53 (2011) Article DOI: 10.1016/j.bmcl.2011.08.064 BindingDB Entry DOI: 10.7270/Q2PG1SQZ
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50355186 (CHEMBL1835625) Show SMILES Cc1cccc(n1)-c1nn(cc1-c1ccc2ncnn2c1)C(=S)Nc1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C22H15Cl2N7S/c1-13-3-2-4-19(27-13)21-18(14-5-6-20-25-12-26-30(20)10-14)11-31(29-21)22(32)28-17-8-15(23)7-16(24)9-17/h2-12H,1H3,(H,28,32)	PDB MMDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.85E+3	n/a	n/a	n/a	n/a	n/a	n/a
Ewha Womans University Curated by ChEMBL					Assay Description Inhibition of human recombinant p38alpha expressed in Escherichia coli using ATF2 as a substrate by radioisotopic protein kinase assay				Bioorg Med Chem Lett 21: 6049-53 (2011) Article DOI: 10.1016/j.bmcl.2011.08.064 BindingDB Entry DOI: 10.7270/Q2PG1SQZ
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50355200 (CHEMBL1835528) Show SMILES Cc1ccc(NC(=S)n2cc(c(n2)-c2cccc(C)n2)-c2ccc3ncnn3c2)cc1 Show InChI InChI=1S/C23H19N7S/c1-15-6-9-18(10-7-15)27-23(31)30-13-19(17-8-11-21-24-14-25-29(21)12-17)22(28-30)20-5-3-4-16(2)26-20/h3-14H,1-2H3,(H,27,31)	PDB MMDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.96E+3	n/a	n/a	n/a	n/a	n/a	n/a
Ewha Womans University Curated by ChEMBL					Assay Description Inhibition of human recombinant p38alpha expressed in Escherichia coli using ATF2 as a substrate by radioisotopic protein kinase assay				Bioorg Med Chem Lett 21: 6049-53 (2011) Article DOI: 10.1016/j.bmcl.2011.08.064 BindingDB Entry DOI: 10.7270/Q2PG1SQZ
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50355194 (CHEMBL1835534) Show SMILES Cc1cccc(n1)-c1nn(cc1-c1ccc2ncnn2c1)C(=S)Nc1ccccc1F Show InChI InChI=1S/C22H16FN7S/c1-14-5-4-8-19(26-14)21-16(15-9-10-20-24-13-25-29(20)11-15)12-30(28-21)22(31)27-18-7-3-2-6-17(18)23/h2-13H,1H3,(H,27,31)	PDB MMDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Ewha Womans University Curated by ChEMBL					Assay Description Inhibition of human recombinant p38alpha expressed in Escherichia coli using ATF2 as a substrate by radioisotopic protein kinase assay				Bioorg Med Chem Lett 21: 6049-53 (2011) Article DOI: 10.1016/j.bmcl.2011.08.064 BindingDB Entry DOI: 10.7270/Q2PG1SQZ
					More data for this Ligand-Target Pair

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