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Found 18 Enz. Inhib. hit(s) with all data for entry = 50040273
LigandPNGBDBM104963(CHEMBL507361 | US11147816, PD0325901 | US11701360,...)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of MEK1-mediated ERK2 T202/Y204 phosphorylation using biotinylated MBP as substrate preincubated for 30 mins measured after 100 mins by cR...More data for this Ligand-Target Pair
LigandPNGBDBM50391802((3,4-difluoro-2-(2-fluoro-4-iodophenylamino)phenyl...)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of MEK1-mediated ERK2 T202/Y204 phosphorylation using biotinylated MBP as substrate preincubated for 30 mins measured after 100 mins by cR...More data for this Ligand-Target Pair
LigandPNGBDBM50391804(CHEMBL2146893)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of MEK1-mediated ERK2 T202/Y204 phosphorylation using biotinylated MBP as substrate preincubated for 30 mins measured after 100 mins by cR...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50391805(CHEMBL2146894)
Affinity DataIC50:  4.80nMAssay Description:Inhibition of MEK1-mediated ERK2 T202/Y204 phosphorylation using biotinylated MBP as substrate preincubated for 30 mins measured after 100 mins by cR...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50391811(CHEMBL2146895)
Affinity DataIC50:  5.10nMAssay Description:Inhibition of MEK1-mediated ERK2 T202/Y204 phosphorylation using biotinylated MBP as substrate preincubated for 30 mins measured after 100 mins by cR...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50391800(CHEMBL2146898)
Affinity DataIC50:  5.20nMAssay Description:Inhibition of MEK1-mediated ERK2 T202/Y204 phosphorylation using biotinylated MBP as substrate preincubated for 30 mins measured after 100 mins by cR...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50391803(CHEMBL2146888)
Affinity DataIC50:  6.60nMAssay Description:Inhibition of MEK1-mediated ERK2 T202/Y204 phosphorylation using biotinylated MBP as substrate preincubated for 30 mins measured after 100 mins by cR...More data for this Ligand-Target Pair
LigandPNGBDBM50391801(CHEMBL2146892)
Affinity DataIC50:  7.20nMAssay Description:Inhibition of MEK1-mediated ERK2 T202/Y204 phosphorylation using biotinylated MBP as substrate preincubated for 30 mins measured after 100 mins by cR...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50391808(CHEMBL2146896)
Affinity DataIC50:  7.60nMAssay Description:Inhibition of MEK1-mediated ERK2 T202/Y204 phosphorylation using biotinylated MBP as substrate preincubated for 30 mins measured after 100 mins by cR...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50391806(CHEMBL2146899)
Affinity DataIC50:  16nMAssay Description:Inhibition of MEK1-mediated ERK2 T202/Y204 phosphorylation using biotinylated MBP as substrate preincubated for 30 mins measured after 100 mins by cR...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50391812(CHEMBL2146885)
Affinity DataIC50:  19.5nMAssay Description:Inhibition of MEK1-mediated ERK2 T202/Y204 phosphorylation using biotinylated MBP as substrate preincubated for 30 mins measured after 100 mins by cR...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50391797(CHEMBL2146890)
Affinity DataIC50:  27nMAssay Description:Inhibition of MEK1-mediated ERK2 T202/Y204 phosphorylation using biotinylated MBP as substrate preincubated for 30 mins measured after 100 mins by cR...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50391809(CHEMBL2146887)
Affinity DataIC50:  44nMAssay Description:Inhibition of MEK1-mediated ERK2 T202/Y204 phosphorylation using biotinylated MBP as substrate preincubated for 30 mins measured after 100 mins by cR...More data for this Ligand-Target Pair
LigandPNGBDBM50391807(CHEMBL2146889)
Affinity DataIC50:  82nMAssay Description:Inhibition of MEK1-mediated ERK2 T202/Y204 phosphorylation using biotinylated MBP as substrate preincubated for 30 mins measured after 100 mins by cR...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50391798(CHEMBL2146891)
Affinity DataIC50:  220nMAssay Description:Inhibition of MEK1-mediated ERK2 T202/Y204 phosphorylation using biotinylated MBP as substrate preincubated for 30 mins measured after 100 mins by cR...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50391813(CHEMBL2146886)
Affinity DataIC50:  535nMAssay Description:Inhibition of MEK1-mediated ERK2 T202/Y204 phosphorylation using biotinylated MBP as substrate preincubated for 30 mins measured after 100 mins by cR...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50391810(CHEMBL2146884)
Affinity DataIC50:  801nMAssay Description:Inhibition of MEK1-mediated ERK2 T202/Y204 phosphorylation using biotinylated MBP as substrate preincubated for 30 mins measured after 100 mins by cR...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50391799(CHEMBL2146897)
Affinity DataIC50:  1.71E+3nMAssay Description:Inhibition of MEK1-mediated ERK2 T202/Y204 phosphorylation using biotinylated MBP as substrate preincubated for 30 mins measured after 100 mins by cR...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed