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Found 40 Enz. Inhib. hit(s) with all data for entry = 50040372
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Wroclaw University Of Technology

Curated by ChEMBL
LigandPNGBDBM50303320((S)-2-[(R)-3-[((R)-1-Benzyloxycarbonylamino-2-phen...)
Affinity DataKi:  0.650nMAssay Description:Inhibition of human ACE C-terminal domain expressed in CHO cells after 90 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Wroclaw University Of Technology

Curated by ChEMBL
LigandPNGBDBM50018849(4-Cyclohexyl-1-{2-[hydroxy-(4-phenyl-butyl)-phosph...)
Affinity DataKi:  1.5nMAssay Description:Inhibition of ACEMore data for this Ligand-Target Pair
TargetAminopeptidase N(Homo sapiens (Human))
Wroclaw University Of Technology

Curated by ChEMBL
LigandPNGBDBM50393210(CHEMBL1235787)
Affinity DataKi:  2.20nMAssay Description:Inhibition of APNMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Wroclaw University Of Technology

Curated by ChEMBL
LigandPNGBDBM50393211(CHEMBL2153737)
Affinity DataKi:  2.5nMAssay Description:Inhibition of MMP-8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Wroclaw University Of Technology

Curated by ChEMBL
LigandPNGBDBM50303327((2S)-2-((1S,2S)-2-(((R)-1-(benzyloxycarbonylamino)...)
Affinity DataKi:  3nMAssay Description:Inhibition of human ACE C-terminal domain expressed in CHO cells after 90 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetStromelysin-3(Homo sapiens (Human))
Wroclaw University Of Technology

Curated by ChEMBL
LigandPNGBDBM50393211(CHEMBL2153737)
Affinity DataKi:  5nMAssay Description:Inhibition of MMP-11More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Wroclaw University Of Technology

Curated by ChEMBL
LigandPNGBDBM50393213(CHEMBL1235767)
Affinity DataKi:  7nMAssay Description:Inhibition of human ACE N-terminal domain expressed in CHO cells after 90 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Wroclaw University Of Technology

Curated by ChEMBL
LigandPNGBDBM50393211(CHEMBL2153737)
Affinity DataKi:  10nMAssay Description:Inhibition of MMP-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Leishmania major)
Wroclaw University Of Technology

Curated by ChEMBL
LigandPNGBDBM50098390((3-methylpyridin-2-ylamino)methylenediphosphonic a...)
Affinity DataKi:  11nMAssay Description:Inhibition of Leishmania major FPPSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Wroclaw University Of Technology

Curated by ChEMBL
LigandPNGBDBM50393211(CHEMBL2153737)
Affinity DataKi:  20nMAssay Description:Inhibition of MMP-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Wroclaw University Of Technology

Curated by ChEMBL
LigandPNGBDBM50393212(CHEMBL2153739)
Affinity DataKi:  28nMAssay Description:Inhibition of MMP-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytosol aminopeptidase(Homo sapiens (Human))
Wroclaw University Of Technology

Curated by ChEMBL
LigandPNGBDBM50129683(2-[(1-Amino-3-methyl-butyl)-hydroxy-phosphinoylmet...)
Affinity DataKi:  65nMAssay Description:Inhibition of LAPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Wroclaw University Of Technology

Curated by ChEMBL
LigandPNGBDBM50393211(CHEMBL2153737)
Affinity DataKi:  105nMAssay Description:Inhibition of MMP-14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Wroclaw University Of Technology

Curated by ChEMBL
LigandPNGBDBM50303320((S)-2-[(R)-3-[((R)-1-Benzyloxycarbonylamino-2-phen...)
Affinity DataKi:  150nMAssay Description:Inhibition of human ACE N-terminal domain expressed in CHO cells after 90 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetMatrilysin(Homo sapiens (Human))
Wroclaw University Of Technology

Curated by ChEMBL
LigandPNGBDBM50393207(CHEMBL2153738)
Affinity DataKi: >200nMAssay Description:Inhibition of MMP-7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Wroclaw University Of Technology

Curated by ChEMBL
LigandPNGBDBM50393207(CHEMBL2153738)
Affinity DataKi: >200nMAssay Description:Inhibition of MMP-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-3(Homo sapiens (Human))
Wroclaw University Of Technology

Curated by ChEMBL
LigandPNGBDBM50393207(CHEMBL2153738)
Affinity DataKi:  410nMAssay Description:Inhibition of MMP-11More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Homo sapiens (Human))
Wroclaw University Of Technology

Curated by ChEMBL
LigandPNGBDBM50129683(2-[(1-Amino-3-methyl-butyl)-hydroxy-phosphinoylmet...)
Affinity DataKi:  1.02E+3nMAssay Description:Inhibition of APNMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrilysin(Homo sapiens (Human))
Wroclaw University Of Technology

Curated by ChEMBL
LigandPNGBDBM50393211(CHEMBL2153737)
Affinity DataKi: >2.00E+3nMAssay Description:Inhibition of MMP-7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Wroclaw University Of Technology

Curated by ChEMBL
LigandPNGBDBM50393211(CHEMBL2153737)
Affinity DataKi: >2.00E+3nMAssay Description:Inhibition of MMP-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Wroclaw University Of Technology

Curated by ChEMBL
LigandPNGBDBM50393212(CHEMBL2153739)
Affinity DataKi:  5.10E+3nMAssay Description:Inhibition of MMP-14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Homo sapiens (Human))
Wroclaw University Of Technology

Curated by ChEMBL
LigandPNGBDBM50303320((S)-2-[(R)-3-[((R)-1-Benzyloxycarbonylamino-2-phen...)
Affinity DataKi:  6.70E+3nMAssay Description:Inhibition of NEPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Wroclaw University Of Technology

Curated by ChEMBL
LigandPNGBDBM50393213(CHEMBL1235767)
Affinity DataKi:  7.50E+3nMAssay Description:Inhibition of human ACE C-terminal domain expressed in CHO cells after 90 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Wroclaw University Of Technology

Curated by ChEMBL
LigandPNGBDBM50303327((2S)-2-((1S,2S)-2-(((R)-1-(benzyloxycarbonylamino)...)
Affinity DataKi:  1.00E+4nMAssay Description:Inhibition of human ACE N-terminal domain expressed in CHO cells after 90 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Wroclaw University Of Technology

Curated by ChEMBL
LigandPNGBDBM50393207(CHEMBL2153738)
Affinity DataKi:  3.00E+4nMAssay Description:Inhibition of MMP-14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytosol aminopeptidase(Homo sapiens (Human))
Wroclaw University Of Technology

Curated by ChEMBL
LigandPNGBDBM50393208(CHEMBL2153735)
Affinity DataKi:  5.80E+4nMAssay Description:Inhibition of LAPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Wroclaw University Of Technology

Curated by ChEMBL
LigandPNGBDBM50393207(CHEMBL2153738)
Affinity DataKi:  1.48E+5nMAssay Description:Inhibition of MMP-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Wroclaw University Of Technology

Curated by ChEMBL
LigandPNGBDBM50393207(CHEMBL2153738)
Affinity DataKi: >2.00E+5nMAssay Description:Inhibition of MMP-8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Wroclaw University Of Technology

Curated by ChEMBL
LigandPNGBDBM50393207(CHEMBL2153738)
Affinity DataKi: >2.00E+5nMAssay Description:Inhibition of MMP-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Wroclaw University Of Technology

Curated by ChEMBL
LigandPNGBDBM50393207(CHEMBL2153738)
Affinity DataKi: >2.00E+5nMAssay Description:Inhibition of MMP-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Wroclaw University Of Technology

Curated by ChEMBL
LigandPNGBDBM12578(2-(imidazol-1-yl)-1-hydroxyethylidene-1,1-bisphosp...)
Affinity DataIC50:  3nMAssay Description:Inhibition of recombinant human FPPS expressed in Escherichia coli by scintillation countingMore data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Wroclaw University Of Technology

Curated by ChEMBL
LigandPNGBDBM12576(Bisphosphonate 1 | CHEMBL923 | JMC515594 Compound ...)
Affinity DataIC50:  10nMAssay Description:Inhibition of recombinant human FPPS expressed in Escherichia coli by scintillation countingMore data for this Ligand-Target Pair
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Wroclaw University Of Technology

Curated by ChEMBL
LigandPNGBDBM50393206(CHEMBL2153745)
Affinity DataIC50:  12nMAssay Description:Inhibition of ACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Wroclaw University Of Technology

Curated by ChEMBL
LigandPNGBDBM50393204(CHEMBL2153743)
Affinity DataIC50:  16nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Wroclaw University Of Technology

Curated by ChEMBL
LigandPNGBDBM50393205(CHEMBL2153744)
Affinity DataIC50:  23nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Wroclaw University Of Technology

Curated by ChEMBL
LigandPNGBDBM50135821((Bis-phosphono-methyl)-cycloheptyl-ammonium | (Cyc...)
Affinity DataIC50:  30nMAssay Description:Inhibition of recombinant human FPPS expressed in Escherichia coli by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Wroclaw University Of Technology

Curated by ChEMBL
LigandPNGBDBM25313((4-amino-1-hydroxy-1-phosphonobutyl)phosphonic aci...)
Affinity DataIC50:  50nMAssay Description:Inhibition of recombinant human FPPS expressed in Escherichia coli by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Wroclaw University Of Technology

Curated by ChEMBL
LigandPNGBDBM12581((3-amino-1-hydroxy-1-phosphonopropyl)phosphonic ac...)
Affinity DataIC50:  200nMAssay Description:Inhibition of recombinant human FPPS expressed in Escherichia coli by scintillation countingMore data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Wroclaw University Of Technology

Curated by ChEMBL
LigandPNGBDBM50393203(CHEMBL2153742)
Affinity DataIC50:  400nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Wroclaw University Of Technology

Curated by ChEMBL
LigandPNGBDBM50393202(CHEMBL1182947)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed