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Compile Data Set for Download or QSAR

Found 30 hits Enz. Inhib. hit(s) with all data for entry = 50042906   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50433055
PNG
(CHEMBL2376113)
Show SMILES ONC(=O)CN1C(=O)C2(OCCCCO2)c2cc(Cl)ccc12
Show InChI InChI=1S/C14H15ClN2O5/c15-9-3-4-11-10(7-9)14(21-5-1-2-6-22-14)13(19)17(11)8-12(18)16-20/h3-4,7,20H,1-2,5-6,8H2,(H,16,18)
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n/an/a 74n/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Inhibition of pig kidney microsome aminopeptidase-N using L-leu-p-nitroanilide as substrate incubated for 5 mins prior to substrate addition measured...


Bioorg Med Chem 21: 2663-70 (2013)


Article DOI: 10.1016/j.bmc.2012.06.024
BindingDB Entry DOI: 10.7270/Q2J67J8H
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50433053
PNG
(CHEMBL2376115)
Show SMILES ONC(=O)CN1C(=O)C2(OCCCCO2)c2cc(Br)ccc12
Show InChI InChI=1S/C14H15BrN2O5/c15-9-3-4-11-10(7-9)14(21-5-1-2-6-22-14)13(19)17(11)8-12(18)16-20/h3-4,7,20H,1-2,5-6,8H2,(H,16,18)
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n/an/a 86n/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Inhibition of pig kidney microsome aminopeptidase-N using L-leu-p-nitroanilide as substrate incubated for 5 mins prior to substrate addition measured...


Bioorg Med Chem 21: 2663-70 (2013)


Article DOI: 10.1016/j.bmc.2012.06.024
BindingDB Entry DOI: 10.7270/Q2J67J8H
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50433060
PNG
(CHEMBL2376104)
Show SMILES ONC(=O)CN1C(=O)C2(OCCO2)c2cc(Cl)ccc12
Show InChI InChI=1S/C12H11ClN2O5/c13-7-1-2-9-8(5-7)12(19-3-4-20-12)11(17)15(9)6-10(16)14-18/h1-2,5,18H,3-4,6H2,(H,14,16)
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n/an/a 310n/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Inhibition of pig kidney microsome aminopeptidase-N using L-leu-p-nitroanilide as substrate incubated for 5 mins prior to substrate addition measured...


Bioorg Med Chem 21: 2663-70 (2013)


Article DOI: 10.1016/j.bmc.2012.06.024
BindingDB Entry DOI: 10.7270/Q2J67J8H
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50396827
PNG
(CHEMBL1712297)
Show SMILES ONC(=O)CN1C(=O)C2(OCCO2)c2cc(Br)ccc12
Show InChI InChI=1S/C12H11BrN2O5/c13-7-1-2-9-8(5-7)12(19-3-4-20-12)11(17)15(9)6-10(16)14-18/h1-2,5,18H,3-4,6H2,(H,14,16)
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n/an/a 360n/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Inhibition of pig kidney microsome aminopeptidase-N using L-leu-p-nitroanilide as substrate incubated for 5 mins prior to substrate addition measured...


Bioorg Med Chem 21: 2663-70 (2013)


Article DOI: 10.1016/j.bmc.2012.06.024
BindingDB Entry DOI: 10.7270/Q2J67J8H
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50433058
PNG
(CHEMBL2376108)
Show SMILES ONC(=O)CN1C(=O)C2(OCCCO2)c2cc(Cl)ccc12
Show InChI InChI=1S/C13H13ClN2O5/c14-8-2-3-10-9(6-8)13(20-4-1-5-21-13)12(18)16(10)7-11(17)15-19/h2-3,6,19H,1,4-5,7H2,(H,15,17)
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n/an/a 1.30E+3n/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Inhibition of pig kidney microsome aminopeptidase-N using L-leu-p-nitroanilide as substrate incubated for 5 mins prior to substrate addition measured...


Bioorg Med Chem 21: 2663-70 (2013)


Article DOI: 10.1016/j.bmc.2012.06.024
BindingDB Entry DOI: 10.7270/Q2J67J8H
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM23971
PNG
((2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanami...)
Show SMILES CC(C)C[C@H](NC(=O)[C@@H](O)[C@H](N)Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C16H24N2O4/c1-10(2)8-13(16(21)22)18-15(20)14(19)12(17)9-11-6-4-3-5-7-11/h3-7,10,12-14,19H,8-9,17H2,1-2H3,(H,18,20)(H,21,22)/t12-,13+,14+/m1/s1
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n/an/a 1.30E+3n/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Inhibition of pig kidney microsome aminopeptidase-N using L-leu-p-nitroanilide as substrate incubated for 5 mins prior to substrate addition measured...


Bioorg Med Chem 21: 2663-70 (2013)


Article DOI: 10.1016/j.bmc.2012.06.024
BindingDB Entry DOI: 10.7270/Q2J67J8H
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50433069
PNG
(CHEMBL2376107)
Show SMILES Cc1ccc2N(CC(=O)NO)C(=O)C3(OCCO3)c2c1
Show InChI InChI=1S/C13H14N2O5/c1-8-2-3-10-9(6-8)13(19-4-5-20-13)12(17)15(10)7-11(16)14-18/h2-3,6,18H,4-5,7H2,1H3,(H,14,16)
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n/an/a 2.63E+3n/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Inhibition of pig kidney microsome aminopeptidase-N using L-leu-p-nitroanilide as substrate incubated for 5 mins prior to substrate addition measured...


Bioorg Med Chem 21: 2663-70 (2013)


Article DOI: 10.1016/j.bmc.2012.06.024
BindingDB Entry DOI: 10.7270/Q2J67J8H
More data for this
Ligand-Target Pair
Aminopeptidase N


(Homo sapiens (Human))
BDBM50433055
PNG
(CHEMBL2376113)
Show SMILES ONC(=O)CN1C(=O)C2(OCCCCO2)c2cc(Cl)ccc12
Show InChI InChI=1S/C14H15ClN2O5/c15-9-3-4-11-10(7-9)14(21-5-1-2-6-22-14)13(19)17(11)8-12(18)16-20/h3-4,7,20H,1-2,5-6,8H2,(H,16,18)
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n/an/a 3.12E+3n/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Inhibition of aminopeptidase-N in human ES2 cells using L-leu-p-nitroanilide as substrate incubated for 5 mins prior to substrate addition measured a...


Bioorg Med Chem 21: 2663-70 (2013)


Article DOI: 10.1016/j.bmc.2012.06.024
BindingDB Entry DOI: 10.7270/Q2J67J8H
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50433067
PNG
(CHEMBL2376112)
Show SMILES Cc1ccc2N(CC(=O)NO)C(=O)C3(OCCCO3)c2c1
Show InChI InChI=1S/C14H16N2O5/c1-9-3-4-11-10(7-9)14(20-5-2-6-21-14)13(18)16(11)8-12(17)15-19/h3-4,7,19H,2,5-6,8H2,1H3,(H,15,17)
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n/an/a 3.33E+3n/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Inhibition of pig kidney microsome aminopeptidase-N using L-leu-p-nitroanilide as substrate incubated for 5 mins prior to substrate addition measured...


Bioorg Med Chem 21: 2663-70 (2013)


Article DOI: 10.1016/j.bmc.2012.06.024
BindingDB Entry DOI: 10.7270/Q2J67J8H
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50433056
PNG
(CHEMBL2376110)
Show SMILES ONC(=O)CN1C(=O)C2(OCCCO2)c2cc(Br)ccc12
Show InChI InChI=1S/C13H13BrN2O5/c14-8-2-3-10-9(6-8)13(20-4-1-5-21-13)12(18)16(10)7-11(17)15-19/h2-3,6,19H,1,4-5,7H2,(H,15,17)
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n/an/a 3.40E+3n/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Inhibition of pig kidney microsome aminopeptidase-N using L-leu-p-nitroanilide as substrate incubated for 5 mins prior to substrate addition measured...


Bioorg Med Chem 21: 2663-70 (2013)


Article DOI: 10.1016/j.bmc.2012.06.024
BindingDB Entry DOI: 10.7270/Q2J67J8H
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50433054
PNG
(CHEMBL2376114)
Show SMILES ONC(=O)CN1C(=O)C2(OCCCCO2)c2cc(F)ccc12
Show InChI InChI=1S/C14H15FN2O5/c15-9-3-4-11-10(7-9)14(21-5-1-2-6-22-14)13(19)17(11)8-12(18)16-20/h3-4,7,20H,1-2,5-6,8H2,(H,16,18)
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n/an/a 4.06E+3n/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Inhibition of pig kidney microsome aminopeptidase-N using L-leu-p-nitroanilide as substrate incubated for 5 mins prior to substrate addition measured...


Bioorg Med Chem 21: 2663-70 (2013)


Article DOI: 10.1016/j.bmc.2012.06.024
BindingDB Entry DOI: 10.7270/Q2J67J8H
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50433059
PNG
(CHEMBL2376105)
Show SMILES ONC(=O)CN1C(=O)C2(OCCO2)c2cc(F)ccc12
Show InChI InChI=1S/C12H11FN2O5/c13-7-1-2-9-8(5-7)12(19-3-4-20-12)11(17)15(9)6-10(16)14-18/h1-2,5,18H,3-4,6H2,(H,14,16)
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n/an/a 5.30E+3n/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Inhibition of pig kidney microsome aminopeptidase-N using L-leu-p-nitroanilide as substrate incubated for 5 mins prior to substrate addition measured...


Bioorg Med Chem 21: 2663-70 (2013)


Article DOI: 10.1016/j.bmc.2012.06.024
BindingDB Entry DOI: 10.7270/Q2J67J8H
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50433066
PNG
(CHEMBL2376116)
Show SMILES ONC(=O)CNC(=O)CN1C(=O)C2(OCCO2)c2cc(Br)ccc12
Show InChI InChI=1S/C14H14BrN3O6/c15-8-1-2-10-9(5-8)14(23-3-4-24-14)13(21)18(10)7-12(20)16-6-11(19)17-22/h1-2,5,22H,3-4,6-7H2,(H,16,20)(H,17,19)
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n/an/a 6.60E+3n/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Inhibition of pig kidney microsome aminopeptidase-N using L-leu-p-nitroanilide as substrate incubated for 5 mins prior to substrate addition measured...


Bioorg Med Chem 21: 2663-70 (2013)


Article DOI: 10.1016/j.bmc.2012.06.024
BindingDB Entry DOI: 10.7270/Q2J67J8H
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50433057
PNG
(CHEMBL2376109)
Show SMILES ONC(=O)CN1C(=O)C2(OCCCO2)c2cc(F)ccc12
Show InChI InChI=1S/C13H13FN2O5/c14-8-2-3-10-9(6-8)13(20-4-1-5-21-13)12(18)16(10)7-11(17)15-19/h2-3,6,19H,1,4-5,7H2,(H,15,17)
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n/an/a 6.71E+3n/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Inhibition of pig kidney microsome aminopeptidase-N using L-leu-p-nitroanilide as substrate incubated for 5 mins prior to substrate addition measured...


Bioorg Med Chem 21: 2663-70 (2013)


Article DOI: 10.1016/j.bmc.2012.06.024
BindingDB Entry DOI: 10.7270/Q2J67J8H
More data for this
Ligand-Target Pair
Aminopeptidase N


(Homo sapiens (Human))
BDBM50433060
PNG
(CHEMBL2376104)
Show SMILES ONC(=O)CN1C(=O)C2(OCCO2)c2cc(Cl)ccc12
Show InChI InChI=1S/C12H11ClN2O5/c13-7-1-2-9-8(5-7)12(19-3-4-20-12)11(17)15(9)6-10(16)14-18/h1-2,5,18H,3-4,6H2,(H,14,16)
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n/an/a 9.58E+3n/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Inhibition of aminopeptidase-N in human ES2 cells using L-leu-p-nitroanilide as substrate incubated for 5 mins prior to substrate addition measured a...


Bioorg Med Chem 21: 2663-70 (2013)


Article DOI: 10.1016/j.bmc.2012.06.024
BindingDB Entry DOI: 10.7270/Q2J67J8H
More data for this
Ligand-Target Pair
Aminopeptidase N


(Homo sapiens (Human))
BDBM50433058
PNG
(CHEMBL2376108)
Show SMILES ONC(=O)CN1C(=O)C2(OCCCO2)c2cc(Cl)ccc12
Show InChI InChI=1S/C13H13ClN2O5/c14-8-2-3-10-9(6-8)13(20-4-1-5-21-13)12(18)16(10)7-11(17)15-19/h2-3,6,19H,1,4-5,7H2,(H,15,17)
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n/an/a 1.09E+4n/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Inhibition of aminopeptidase-N in human ES2 cells using L-leu-p-nitroanilide as substrate incubated for 5 mins prior to substrate addition measured a...


Bioorg Med Chem 21: 2663-70 (2013)


Article DOI: 10.1016/j.bmc.2012.06.024
BindingDB Entry DOI: 10.7270/Q2J67J8H
More data for this
Ligand-Target Pair
Aminopeptidase N


(Homo sapiens (Human))
BDBM50433053
PNG
(CHEMBL2376115)
Show SMILES ONC(=O)CN1C(=O)C2(OCCCCO2)c2cc(Br)ccc12
Show InChI InChI=1S/C14H15BrN2O5/c15-9-3-4-11-10(7-9)14(21-5-1-2-6-22-14)13(19)17(11)8-12(18)16-20/h3-4,7,20H,1-2,5-6,8H2,(H,16,18)
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n/an/a 1.21E+4n/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Inhibition of aminopeptidase-N in human ES2 cells using L-leu-p-nitroanilide as substrate incubated for 5 mins prior to substrate addition measured a...


Bioorg Med Chem 21: 2663-70 (2013)


Article DOI: 10.1016/j.bmc.2012.06.024
BindingDB Entry DOI: 10.7270/Q2J67J8H
More data for this
Ligand-Target Pair
Aminopeptidase N


(Homo sapiens (Human))
BDBM50396827
PNG
(CHEMBL1712297)
Show SMILES ONC(=O)CN1C(=O)C2(OCCO2)c2cc(Br)ccc12
Show InChI InChI=1S/C12H11BrN2O5/c13-7-1-2-9-8(5-7)12(19-3-4-20-12)11(17)15(9)6-10(16)14-18/h1-2,5,18H,3-4,6H2,(H,14,16)
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n/an/a 1.24E+4n/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Inhibition of aminopeptidase-N in human ES2 cells using L-leu-p-nitroanilide as substrate incubated for 5 mins prior to substrate addition measured a...


Bioorg Med Chem 21: 2663-70 (2013)


Article DOI: 10.1016/j.bmc.2012.06.024
BindingDB Entry DOI: 10.7270/Q2J67J8H
More data for this
Ligand-Target Pair
Aminopeptidase N


(Homo sapiens (Human))
BDBM50433054
PNG
(CHEMBL2376114)
Show SMILES ONC(=O)CN1C(=O)C2(OCCCCO2)c2cc(F)ccc12
Show InChI InChI=1S/C14H15FN2O5/c15-9-3-4-11-10(7-9)14(21-5-1-2-6-22-14)13(19)17(11)8-12(18)16-20/h3-4,7,20H,1-2,5-6,8H2,(H,16,18)
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n/an/a 1.52E+4n/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Inhibition of aminopeptidase-N in human ES2 cells using L-leu-p-nitroanilide as substrate incubated for 5 mins prior to substrate addition measured a...


Bioorg Med Chem 21: 2663-70 (2013)


Article DOI: 10.1016/j.bmc.2012.06.024
BindingDB Entry DOI: 10.7270/Q2J67J8H
More data for this
Ligand-Target Pair
Aminopeptidase N


(Homo sapiens (Human))
BDBM50433059
PNG
(CHEMBL2376105)
Show SMILES ONC(=O)CN1C(=O)C2(OCCO2)c2cc(F)ccc12
Show InChI InChI=1S/C12H11FN2O5/c13-7-1-2-9-8(5-7)12(19-3-4-20-12)11(17)15(9)6-10(16)14-18/h1-2,5,18H,3-4,6H2,(H,14,16)
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n/an/a 1.62E+4n/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Inhibition of aminopeptidase-N in human ES2 cells using L-leu-p-nitroanilide as substrate incubated for 5 mins prior to substrate addition measured a...


Bioorg Med Chem 21: 2663-70 (2013)


Article DOI: 10.1016/j.bmc.2012.06.024
BindingDB Entry DOI: 10.7270/Q2J67J8H
More data for this
Ligand-Target Pair
Aminopeptidase N


(Homo sapiens (Human))
BDBM50433056
PNG
(CHEMBL2376110)
Show SMILES ONC(=O)CN1C(=O)C2(OCCCO2)c2cc(Br)ccc12
Show InChI InChI=1S/C13H13BrN2O5/c14-8-2-3-10-9(6-8)13(20-4-1-5-21-13)12(18)16(10)7-11(17)15-19/h2-3,6,19H,1,4-5,7H2,(H,15,17)
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n/an/a 1.97E+4n/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Inhibition of aminopeptidase-N in human ES2 cells using L-leu-p-nitroanilide as substrate incubated for 5 mins prior to substrate addition measured a...


Bioorg Med Chem 21: 2663-70 (2013)


Article DOI: 10.1016/j.bmc.2012.06.024
BindingDB Entry DOI: 10.7270/Q2J67J8H
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50433064
PNG
(CHEMBL2376100)
Show SMILES CC(C)C[C@H](NC(=O)CN1C(=O)C2(OCCO2)c2cc(Br)ccc12)C(=O)NO
Show InChI InChI=1S/C18H22BrN3O6/c1-10(2)7-13(16(24)21-26)20-15(23)9-22-14-4-3-11(19)8-12(14)18(17(22)25)27-5-6-28-18/h3-4,8,10,13,26H,5-7,9H2,1-2H3,(H,20,23)(H,21,24)/t13-/m0/s1
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n/an/a 2.25E+4n/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Inhibition of pig kidney microsome aminopeptidase-N using L-leu-p-nitroanilide as substrate incubated for 5 mins prior to substrate addition measured...


Bioorg Med Chem 21: 2663-70 (2013)


Article DOI: 10.1016/j.bmc.2012.06.024
BindingDB Entry DOI: 10.7270/Q2J67J8H
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50433065
PNG
(CHEMBL2376117)
Show SMILES ONC(=O)[C@H](Cc1ccccc1)NC(=O)CN1C(=O)C2(OCCO2)c2cc(Br)ccc12
Show InChI InChI=1S/C21H20BrN3O6/c22-14-6-7-17-15(11-14)21(30-8-9-31-21)20(28)25(17)12-18(26)23-16(19(27)24-29)10-13-4-2-1-3-5-13/h1-7,11,16,29H,8-10,12H2,(H,23,26)(H,24,27)/t16-/m0/s1
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n/an/a 2.64E+4n/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Inhibition of pig kidney microsome aminopeptidase-N using L-leu-p-nitroanilide as substrate incubated for 5 mins prior to substrate addition measured...


Bioorg Med Chem 21: 2663-70 (2013)


Article DOI: 10.1016/j.bmc.2012.06.024
BindingDB Entry DOI: 10.7270/Q2J67J8H
More data for this
Ligand-Target Pair
Aminopeptidase N


(Homo sapiens (Human))
BDBM23971
PNG
((2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanami...)
Show SMILES CC(C)C[C@H](NC(=O)[C@@H](O)[C@H](N)Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C16H24N2O4/c1-10(2)8-13(16(21)22)18-15(20)14(19)12(17)9-11-6-4-3-5-7-11/h3-7,10,12-14,19H,8-9,17H2,1-2H3,(H,18,20)(H,21,22)/t12-,13+,14+/m1/s1
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n/an/a 2.97E+4n/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Inhibition of aminopeptidase-N in human ES2 cells using L-leu-p-nitroanilide as substrate incubated for 5 mins prior to substrate addition measured a...


Bioorg Med Chem 21: 2663-70 (2013)


Article DOI: 10.1016/j.bmc.2012.06.024
BindingDB Entry DOI: 10.7270/Q2J67J8H
More data for this
Ligand-Target Pair
Aminopeptidase N


(Homo sapiens (Human))
BDBM50433057
PNG
(CHEMBL2376109)
Show SMILES ONC(=O)CN1C(=O)C2(OCCCO2)c2cc(F)ccc12
Show InChI InChI=1S/C13H13FN2O5/c14-8-2-3-10-9(6-8)13(20-4-1-5-21-13)12(18)16(10)7-11(17)15-19/h2-3,6,19H,1,4-5,7H2,(H,15,17)
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n/an/a 9.75E+4n/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Inhibition of aminopeptidase-N in human ES2 cells using L-leu-p-nitroanilide as substrate incubated for 5 mins prior to substrate addition measured a...


Bioorg Med Chem 21: 2663-70 (2013)


Article DOI: 10.1016/j.bmc.2012.06.024
BindingDB Entry DOI: 10.7270/Q2J67J8H
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50433070
PNG
(CHEMBL2376106)
Show SMILES ONC(=O)CN1C(=O)C2(OCCO2)c2ccccc12
Show InChI InChI=1S/C12H12N2O5/c15-10(13-17)7-14-9-4-2-1-3-8(9)12(11(14)16)18-5-6-19-12/h1-4,17H,5-7H2,(H,13,15)
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n/an/a 2.09E+5n/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Inhibition of pig kidney microsome aminopeptidase-N using L-leu-p-nitroanilide as substrate incubated for 5 mins prior to substrate addition measured...


Bioorg Med Chem 21: 2663-70 (2013)


Article DOI: 10.1016/j.bmc.2012.06.024
BindingDB Entry DOI: 10.7270/Q2J67J8H
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50433061
PNG
(CHEMBL2376103)
Show SMILES CC(C)[C@H](NC(=O)CN1C(=O)C2(OCCO2)c2cc(Br)ccc12)C(=O)NO
Show InChI InChI=1S/C17H20BrN3O6/c1-9(2)14(15(23)20-25)19-13(22)8-21-12-4-3-10(18)7-11(12)17(16(21)24)26-5-6-27-17/h3-4,7,9,14,25H,5-6,8H2,1-2H3,(H,19,22)(H,20,23)/t14-/m0/s1
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n/an/a 2.26E+5n/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Inhibition of pig kidney microsome aminopeptidase-N using L-leu-p-nitroanilide as substrate incubated for 5 mins prior to substrate addition measured...


Bioorg Med Chem 21: 2663-70 (2013)


Article DOI: 10.1016/j.bmc.2012.06.024
BindingDB Entry DOI: 10.7270/Q2J67J8H
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50433068
PNG
(CHEMBL2376111)
Show SMILES ONC(=O)CN1C(=O)C2(OCCCO2)c2ccccc12
Show InChI InChI=1S/C13H14N2O5/c16-11(14-18)8-15-10-5-2-1-4-9(10)13(12(15)17)19-6-3-7-20-13/h1-2,4-5,18H,3,6-8H2,(H,14,16)
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n/an/a 2.66E+5n/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Inhibition of pig kidney microsome aminopeptidase-N using L-leu-p-nitroanilide as substrate incubated for 5 mins prior to substrate addition measured...


Bioorg Med Chem 21: 2663-70 (2013)


Article DOI: 10.1016/j.bmc.2012.06.024
BindingDB Entry DOI: 10.7270/Q2J67J8H
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50433063
PNG
(CHEMBL2376101)
Show SMILES CC[C@H](C)[C@H](NC(=O)CN1C(=O)C2(OCCO2)c2cc(Br)ccc12)C(=O)NO
Show InChI InChI=1S/C18H22BrN3O6/c1-3-10(2)15(16(24)21-26)20-14(23)9-22-13-5-4-11(19)8-12(13)18(17(22)25)27-6-7-28-18/h4-5,8,10,15,26H,3,6-7,9H2,1-2H3,(H,20,23)(H,21,24)/t10-,15-/m0/s1
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n/an/a 6.31E+5n/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Inhibition of pig kidney microsome aminopeptidase-N using L-leu-p-nitroanilide as substrate incubated for 5 mins prior to substrate addition measured...


Bioorg Med Chem 21: 2663-70 (2013)


Article DOI: 10.1016/j.bmc.2012.06.024
BindingDB Entry DOI: 10.7270/Q2J67J8H
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50433062
PNG
(CHEMBL2376102)
Show SMILES ONC(=O)C(NC(=O)CN1C(=O)C2(OCCO2)c2cc(Br)ccc12)c1ccccc1
Show InChI InChI=1S/C20H18BrN3O6/c21-13-6-7-15-14(10-13)20(29-8-9-30-20)19(27)24(15)11-16(25)22-17(18(26)23-28)12-4-2-1-3-5-12/h1-7,10,17,28H,8-9,11H2,(H,22,25)(H,23,26)
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n/an/a>1.00E+6n/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Inhibition of pig kidney microsome aminopeptidase-N using L-leu-p-nitroanilide as substrate incubated for 5 mins prior to substrate addition measured...


Bioorg Med Chem 21: 2663-70 (2013)


Article DOI: 10.1016/j.bmc.2012.06.024
BindingDB Entry DOI: 10.7270/Q2J67J8H
More data for this
Ligand-Target Pair