TargetMitogen-activated protein kinase kinase kinase 10(Homo sapiens (Human))
Califia Bio
Curated by ChEMBL
Califia Bio
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of MLK2 (unknown origin) after 20 mins in presence of [33P]-ATPMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
Califia Bio
Curated by ChEMBL
Califia Bio
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of MLK3 (unknown origin) after 20 mins by scintillation counting analysis in presence of [33P]-ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of wild type human FLT3 by high throughput ATP-[33P] radiolabeled assayMore data for this Ligand-Target Pair
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Califia Bio
Curated by ChEMBL
Califia Bio
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of human wild type LRRK2 by qPCR analysisMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
Califia Bio
Curated by ChEMBL
Califia Bio
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of MLK3 (unknown origin) after 20 mins in presence of [33P]-ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 6.80nMAssay Description:Inhibition of wild type human ABL1 by high throughput ATP-[33P] radiolabeled assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
Califia Bio
Curated by ChEMBL
Califia Bio
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of MLK3 (unknown origin) after 20 mins by scintillation counting analysis in presence of [33P]-ATPMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
Califia Bio
Curated by ChEMBL
Califia Bio
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibition of MLK3 (unknown origin) after 20 mins by scintillation counting analysis in presence of [33P]-ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 9.5nMAssay Description:Inhibition of wild type human FLT3 by high throughput ATP-[33P] radiolabeled assayMore data for this Ligand-Target Pair
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Califia Bio
Curated by ChEMBL
Califia Bio
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of human wild type LRRK2 by qPCR analysisMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
Califia Bio
Curated by ChEMBL
Califia Bio
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of MLK3 (unknown origin) after 20 mins by scintillation counting analysis in presence of [33P]-ATPMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
Califia Bio
Curated by ChEMBL
Califia Bio
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of MLK3 (unknown origin) after 20 mins by scintillation counting analysis in presence of [33P]-ATPMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 9(Homo sapiens (Human))
Califia Bio
Curated by ChEMBL
Califia Bio
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of MLK1 (unknown origin)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
Califia Bio
Curated by ChEMBL
Califia Bio
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Inhibition of MLK3 (unknown origin) after 20 mins by scintillation counting analysis in presence of [33P]-ATPMore data for this Ligand-Target Pair
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Califia Bio
Curated by ChEMBL
Califia Bio
Curated by ChEMBL
Affinity DataIC50: 35nMAssay Description:Inhibition of human wild type LRRK2 by qPCR analysisMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
Califia Bio
Curated by ChEMBL
Califia Bio
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of MLK3 (unknown origin) after 20 mins by scintillation counting analysis in presence of [33P]-ATPMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 10(Homo sapiens (Human))
Califia Bio
Curated by ChEMBL
Califia Bio
Curated by ChEMBL
Affinity DataIC50: 42nMAssay Description:Inhibition of MLK2 (unknown origin)More data for this Ligand-Target Pair
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Califia Bio
Curated by ChEMBL
Califia Bio
Curated by ChEMBL
Affinity DataIC50: 46nMAssay Description:Inhibition of human wild type LRRK2 by qPCR analysisMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
Califia Bio
Curated by ChEMBL
Califia Bio
Curated by ChEMBL
Affinity DataIC50: 78nMAssay Description:Inhibition of MLK3 (unknown origin) after 20 mins by scintillation counting analysis in presence of [33P]-ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 85nMAssay Description:Inhibition of wild type human TRKA by high throughput ATP-[33P] radiolabeled assayMore data for this Ligand-Target Pair
Affinity DataIC50: 108nMAssay Description:Inhibition of wild type human Aurora kinase A by high throughput ATP-[33P] radiolabeled assayMore data for this Ligand-Target Pair
Affinity DataIC50: 111nMAssay Description:Inhibition of wild type human ROCK2 by high throughput ATP-[33P] radiolabeled assayMore data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Inhibition of MLK3 in mouse BV2 cells assessed as inhibition of LPS-induced TNFalpha release after 8 hrs by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 123nMAssay Description:Inhibition of wild type human Aurora kinase B by high throughput ATP-[33P] radiolabeled assayMore data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Inhibition of human wild type DLK by qPCR analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 177nMAssay Description:Inhibition of wild type human c-MET by high throughput ATP-[33P] radiolabeled assayMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of wild type human IR by high throughput ATP-[33P] radiolabeled assayMore data for this Ligand-Target Pair
Affinity DataIC50: 201nMAssay Description:Inhibition of wild type human SGK1 by high throughput ATP-[33P] radiolabeled assayMore data for this Ligand-Target Pair
Affinity DataIC50: 217nMAssay Description:Inhibition of wild type human TRKB by high throughput ATP-[33P] radiolabeled assayMore data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Califia Bio
Curated by ChEMBL
Califia Bio
Curated by ChEMBL
Affinity DataIC50: 257nMAssay Description:Inhibition of wild type human IKKb by high throughput ATP-[33P] radiolabeled assayMore data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Califia Bio
Curated by ChEMBL
Califia Bio
Curated by ChEMBL
Affinity DataIC50: 288nMAssay Description:Inhibition of wild type human IKKb by high throughput ATP-[33P] radiolabeled assayMore data for this Ligand-Target Pair
Affinity DataIC50: 290nMAssay Description:Inhibition of wild type human Aurora kinase C kinase by high throughput ATP-[33P] radiolabeled assayMore data for this Ligand-Target Pair
Affinity DataIC50: 307nMAssay Description:Inhibition of wild type human IGF1R by high throughput ATP-[33P] radiolabeled assayMore data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Homo sapiens (Human))
Califia Bio
Curated by ChEMBL
Califia Bio
Curated by ChEMBL
Affinity DataIC50: 330nMAssay Description:Inhibition of wild type human IKKa by high throughput ATP-[33P] radiolabeled assayMore data for this Ligand-Target Pair
Affinity DataIC50: 430nMAssay Description:Inhibition of MLK3 in mouse BV2 cells assessed as inhibition of LPS-induced TNFalpha release after 8 hrs by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 460nMAssay Description:Inhibition of MLK3 in mouse BV2 cells assessed as inhibition of LPS-induced TNFalpha release after 8 hrs by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 510nMAssay Description:Inhibition of MLK3 in mouse BV2 cells assessed as inhibition of LPS-induced TNFalpha release after 8 hrs by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 560nMAssay Description:Inhibition of FLT3-L-stimulated wild type full length human FLT3 autophosphorylation expressed in MEF preincubated for 90 mins followed by FLT3-L sti...More data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Homo sapiens (Human))
Califia Bio
Curated by ChEMBL
Califia Bio
Curated by ChEMBL
Affinity DataIC50: 591nMAssay Description:Inhibition of wild type human IKKa by high throughput ATP-[33P] radiolabeled assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 2(Homo sapiens (Human))
Califia Bio
Curated by ChEMBL
Califia Bio
Curated by ChEMBL
Affinity DataIC50: 661nMAssay Description:Inhibition of wild type human MEKK2 by high throughput ATP-[33P] radiolabeled assayMore data for this Ligand-Target Pair
Affinity DataIC50: 730nMAssay Description:Inhibition of FLT3-L-stimulated wild type full length human FLT3 autophosphorylation expressed in MEF preincubated for 90 mins followed by FLT3-L sti...More data for this Ligand-Target Pair
Affinity DataIC50: 731nMAssay Description:Inhibition of wild type human SYK by high throughput ATP-[33P] radiolabeled assayMore data for this Ligand-Target Pair
Affinity DataIC50: 990nMAssay Description:Inhibition of MLK3 in mouse BV2 cells assessed as inhibition of LPS-induced TNFalpha release after 8 hrs by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 1.03E+3nMAssay Description:Inhibition of wild type human ROCK1 by high throughput ATP-[33P] radiolabeled assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.13E+3nMAssay Description:Inhibition of wild type human CDK1 by high throughput ATP-[33P] radiolabeled assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.29E+3nMAssay Description:Inhibition of wild type human IR by high throughput ATP-[33P] radiolabeled assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of MLK3 in mouse BV2 cells assessed as inhibition of LPS-induced TNFalpha release after 8 hrs by ELISAMore data for this Ligand-Target Pair
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Califia Bio
Curated by ChEMBL
Califia Bio
Curated by ChEMBL
Affinity DataIC50: 2.97E+3nMAssay Description:Inhibition of human wild type LRRK2 by qPCR analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of CYP2D6 in human liver microsomes assessed as inhibition of diclofenac metabolism by HPLC/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 5.05E+3nMAssay Description:Inhibition of wild type human ZAP70 by high throughput ATP-[33P] radiolabeled assayMore data for this Ligand-Target Pair