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Compile Data Set for Download or QSAR

Found 36 hits Enz. Inhib. hit(s) with all data for entry = 50005405   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50491838
PNG
(CHEMBL2387185)
Show SMILES CCCCn1c2CCCCCCc2cc(C(=O)NC(C)(C)c2ccccc2)c1=O
Show InChI InChI=1S/C25H34N2O2/c1-4-5-17-27-22-16-12-7-6-9-13-19(22)18-21(24(27)29)23(28)26-25(2,3)20-14-10-8-11-15-20/h8,10-11,14-15,18H,4-7,9,12-13,16-17H2,1-3H3,(H,26,28)
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0.100n/an/an/an/an/an/an/an/a



Shionogi Pharmaceutical Research Center

Curated by ChEMBL


Assay Description
Displacement of [3H]-CP-55,940 from human CB2 receptor expressed in CHO cell membranes


Bioorg Med Chem 21: 3154-63 (2013)


BindingDB Entry DOI: 10.7270/Q22R3VKX
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50491839
PNG
(CHEMBL2387183)
Show SMILES CCCCn1c2CCCCCCc2cc(C(=O)NC2CCCCC2)c1=O
Show InChI InChI=1S/C22H34N2O2/c1-2-3-15-24-20-14-10-5-4-7-11-17(20)16-19(22(24)26)21(25)23-18-12-8-6-9-13-18/h16,18H,2-15H2,1H3,(H,23,25)
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0.200n/an/an/an/an/an/an/an/a



Shionogi Pharmaceutical Research Center

Curated by ChEMBL


Assay Description
Displacement of [3H]-CP-55,940 from human CB2 receptor expressed in CHO cell membranes


Bioorg Med Chem 21: 3154-63 (2013)


BindingDB Entry DOI: 10.7270/Q22R3VKX
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50491833
PNG
(CHEMBL2387178)
Show SMILES CC(C)CCn1c2CCCCCCc2cc(C(=O)NCc2ccccc2)c1=O
Show InChI InChI=1S/C24H32N2O2/c1-18(2)14-15-26-22-13-9-4-3-8-12-20(22)16-21(24(26)28)23(27)25-17-19-10-6-5-7-11-19/h5-7,10-11,16,18H,3-4,8-9,12-15,17H2,1-2H3,(H,25,27)
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0.900n/an/an/an/an/an/an/an/a



Shionogi Pharmaceutical Research Center

Curated by ChEMBL


Assay Description
Displacement of [3H]-CP-55,940 from human CB2 receptor expressed in CHO cell membranes


Bioorg Med Chem 21: 3154-63 (2013)


BindingDB Entry DOI: 10.7270/Q22R3VKX
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50491838
PNG
(CHEMBL2387185)
Show SMILES CCCCn1c2CCCCCCc2cc(C(=O)NC(C)(C)c2ccccc2)c1=O
Show InChI InChI=1S/C25H34N2O2/c1-4-5-17-27-22-16-12-7-6-9-13-19(22)18-21(24(27)29)23(28)26-25(2,3)20-14-10-8-11-15-20/h8,10-11,14-15,18H,4-7,9,12-13,16-17H2,1-3H3,(H,26,28)
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1n/an/an/an/an/an/an/an/a



Shionogi Pharmaceutical Research Center

Curated by ChEMBL


Assay Description
Displacement of [3H]-CP-55,940 from human CB1 receptor expressed in CHO cell membranes


Bioorg Med Chem 21: 3154-63 (2013)


BindingDB Entry DOI: 10.7270/Q22R3VKX
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50491842
PNG
(CHEMBL2387078)
Show SMILES CCCCn1c2CCCCCCc2cc(C(=O)NCc2ccccc2)c1=O
Show InChI InChI=1S/C23H30N2O2/c1-2-3-15-25-21-14-10-5-4-9-13-19(21)16-20(23(25)27)22(26)24-17-18-11-7-6-8-12-18/h6-8,11-12,16H,2-5,9-10,13-15,17H2,1H3,(H,24,26)
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1.5n/an/an/an/an/an/an/an/a



Shionogi Pharmaceutical Research Center

Curated by ChEMBL


Assay Description
Displacement of [3H]-CP-55,940 from human CB2 receptor expressed in CHO cell membranes


Bioorg Med Chem 21: 3154-63 (2013)


BindingDB Entry DOI: 10.7270/Q22R3VKX
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50491840
PNG
(CHEMBL2387186)
Show SMILES CCCCn1c2CCCCCCc2cc(C(=O)NCCc2ccccc2)c1=O
Show InChI InChI=1S/C24H32N2O2/c1-2-3-17-26-22-14-10-5-4-9-13-20(22)18-21(24(26)28)23(27)25-16-15-19-11-7-6-8-12-19/h6-8,11-12,18H,2-5,9-10,13-17H2,1H3,(H,25,27)
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1.60n/an/an/an/an/an/an/an/a



Shionogi Pharmaceutical Research Center

Curated by ChEMBL


Assay Description
Displacement of [3H]-CP-55,940 from human CB2 receptor expressed in CHO cell membranes


Bioorg Med Chem 21: 3154-63 (2013)


BindingDB Entry DOI: 10.7270/Q22R3VKX
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50491831
PNG
(CHEMBL2387182)
Show SMILES CCCCn1c2CCCCCCc2cc(C(=O)NC(C)C)c1=O
Show InChI InChI=1S/C19H30N2O2/c1-4-5-12-21-17-11-9-7-6-8-10-15(17)13-16(19(21)23)18(22)20-14(2)3/h13-14H,4-12H2,1-3H3,(H,20,22)
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4n/an/an/an/an/an/an/an/a



Shionogi Pharmaceutical Research Center

Curated by ChEMBL


Assay Description
Displacement of [3H]-CP-55,940 from human CB2 receptor expressed in CHO cell membranes


Bioorg Med Chem 21: 3154-63 (2013)


BindingDB Entry DOI: 10.7270/Q22R3VKX
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50491841
PNG
(CHEMBL2387179)
Show SMILES COCCn1c2CCCCCCc2cc(C(=O)NCc2ccccc2)c1=O
Show InChI InChI=1S/C22H28N2O3/c1-27-14-13-24-20-12-8-3-2-7-11-18(20)15-19(22(24)26)21(25)23-16-17-9-5-4-6-10-17/h4-6,9-10,15H,2-3,7-8,11-14,16H2,1H3,(H,23,25)
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8n/an/an/an/an/an/an/an/a



Shionogi Pharmaceutical Research Center

Curated by ChEMBL


Assay Description
Displacement of [3H]-CP-55,940 from human CB2 receptor expressed in CHO cell membranes


Bioorg Med Chem 21: 3154-63 (2013)


BindingDB Entry DOI: 10.7270/Q22R3VKX
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50491833
PNG
(CHEMBL2387178)
Show SMILES CC(C)CCn1c2CCCCCCc2cc(C(=O)NCc2ccccc2)c1=O
Show InChI InChI=1S/C24H32N2O2/c1-18(2)14-15-26-22-13-9-4-3-8-12-20(22)16-21(24(26)28)23(27)25-17-19-10-6-5-7-11-19/h5-7,10-11,16,18H,3-4,8-9,12-15,17H2,1-2H3,(H,25,27)
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9n/an/an/an/an/an/an/an/a



Shionogi Pharmaceutical Research Center

Curated by ChEMBL


Assay Description
Displacement of [3H]-CP-55,940 from human CB1 receptor expressed in CHO cell membranes


Bioorg Med Chem 21: 3154-63 (2013)


BindingDB Entry DOI: 10.7270/Q22R3VKX
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM50491839
PNG
(CHEMBL2387183)
Show SMILES CCCCn1c2CCCCCCc2cc(C(=O)NC2CCCCC2)c1=O
Show InChI InChI=1S/C22H34N2O2/c1-2-3-15-24-20-14-10-5-4-7-11-17(20)16-19(22(24)26)21(25)23-18-12-8-6-9-13-18/h16,18H,2-15H2,1H3,(H,23,25)
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12n/an/an/an/an/an/an/an/a



Shionogi Pharmaceutical Research Center

Curated by ChEMBL


Assay Description
Displacement of [3H]-CP-55,940 from mouse brain CB1 receptor expressed in CHO cell membranes


Bioorg Med Chem 21: 3154-63 (2013)


BindingDB Entry DOI: 10.7270/Q22R3VKX
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50491835
PNG
(CHEMBL2387075)
Show SMILES CCCCn1c2CCCc2cc(C(=O)NCc2ccccc2)c1=O
Show InChI InChI=1S/C20H24N2O2/c1-2-3-12-22-18-11-7-10-16(18)13-17(20(22)24)19(23)21-14-15-8-5-4-6-9-15/h4-6,8-9,13H,2-3,7,10-12,14H2,1H3,(H,21,23)
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16n/an/an/an/an/an/an/an/a



Shionogi Pharmaceutical Research Center

Curated by ChEMBL


Assay Description
Displacement of [3H]-CP-55,940 from human CB2 receptor expressed in CHO cell membranes


Bioorg Med Chem 21: 3154-63 (2013)


BindingDB Entry DOI: 10.7270/Q22R3VKX
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50491845
PNG
(CHEMBL2387076)
Show SMILES CCCCn1c2CCCCc2cc(C(=O)NCc2ccccc2)c1=O
Show InChI InChI=1S/C21H26N2O2/c1-2-3-13-23-19-12-8-7-11-17(19)14-18(21(23)25)20(24)22-15-16-9-5-4-6-10-16/h4-6,9-10,14H,2-3,7-8,11-13,15H2,1H3,(H,22,24)
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17n/an/an/an/an/an/an/an/a



Shionogi Pharmaceutical Research Center

Curated by ChEMBL


Assay Description
Displacement of [3H]-CP-55,940 from human CB2 receptor expressed in CHO cell membranes


Bioorg Med Chem 21: 3154-63 (2013)


BindingDB Entry DOI: 10.7270/Q22R3VKX
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50491839
PNG
(CHEMBL2387183)
Show SMILES CCCCn1c2CCCCCCc2cc(C(=O)NC2CCCCC2)c1=O
Show InChI InChI=1S/C22H34N2O2/c1-2-3-15-24-20-14-10-5-4-7-11-17(20)16-19(22(24)26)21(25)23-18-12-8-6-9-13-18/h16,18H,2-15H2,1H3,(H,23,25)
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19n/an/an/an/an/an/an/an/a



Shionogi Pharmaceutical Research Center

Curated by ChEMBL


Assay Description
Displacement of [3H]-CP-55,940 from human CB1 receptor expressed in CHO cell membranes


Bioorg Med Chem 21: 3154-63 (2013)


BindingDB Entry DOI: 10.7270/Q22R3VKX
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50491843
PNG
(CHEMBL2387074)
Show SMILES CCCCn1c(CC)c(C)cc(C(=O)NCc2ccccc2)c1=O
Show InChI InChI=1S/C20H26N2O2/c1-4-6-12-22-18(5-2)15(3)13-17(20(22)24)19(23)21-14-16-10-8-7-9-11-16/h7-11,13H,4-6,12,14H2,1-3H3,(H,21,23)
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20n/an/an/an/an/an/an/an/a



Shionogi Pharmaceutical Research Center

Curated by ChEMBL


Assay Description
Displacement of [3H]-CP-55,940 from human CB2 receptor expressed in CHO cell membranes


Bioorg Med Chem 21: 3154-63 (2013)


BindingDB Entry DOI: 10.7270/Q22R3VKX
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50491844
PNG
(CHEMBL2387181)
Show SMILES CCCCn1c2CCCCCCc2cc(C(N)=O)c1=O
Show InChI InChI=1S/C16H24N2O2/c1-2-3-10-18-14-9-7-5-4-6-8-12(14)11-13(15(17)19)16(18)20/h11H,2-10H2,1H3,(H2,17,19)
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40n/an/an/an/an/an/an/an/a



Shionogi Pharmaceutical Research Center

Curated by ChEMBL


Assay Description
Displacement of [3H]-CP-55,940 from human CB2 receptor expressed in CHO cell membranes


Bioorg Med Chem 21: 3154-63 (2013)


BindingDB Entry DOI: 10.7270/Q22R3VKX
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50491836
PNG
(CHEMBL2387073)
Show SMILES CCCCn1c(C)c(C)cc(C(=O)NCc2ccccc2)c1=O
Show InChI InChI=1S/C19H24N2O2/c1-4-5-11-21-15(3)14(2)12-17(19(21)23)18(22)20-13-16-9-7-6-8-10-16/h6-10,12H,4-5,11,13H2,1-3H3,(H,20,22)
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66n/an/an/an/an/an/an/an/a



Shionogi Pharmaceutical Research Center

Curated by ChEMBL


Assay Description
Displacement of [3H]-CP-55,940 from human CB2 receptor expressed in CHO cell membranes


Bioorg Med Chem 21: 3154-63 (2013)


BindingDB Entry DOI: 10.7270/Q22R3VKX
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50491835
PNG
(CHEMBL2387075)
Show SMILES CCCCn1c2CCCc2cc(C(=O)NCc2ccccc2)c1=O
Show InChI InChI=1S/C20H24N2O2/c1-2-3-12-22-18-11-7-10-16(18)13-17(20(22)24)19(23)21-14-15-8-5-4-6-9-15/h4-6,8-9,13H,2-3,7,10-12,14H2,1H3,(H,21,23)
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143n/an/an/an/an/an/an/an/a



Shionogi Pharmaceutical Research Center

Curated by ChEMBL


Assay Description
Displacement of [3H]-CP-55,940 from human CB1 receptor expressed in CHO cell membranes


Bioorg Med Chem 21: 3154-63 (2013)


BindingDB Entry DOI: 10.7270/Q22R3VKX
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50491830
PNG
(CHEMBL2387184)
Show SMILES CCCCn1c2CCCCCCc2cc(C(=O)NC2CCN(C)CC2)c1=O
Show InChI InChI=1S/C22H35N3O2/c1-3-4-13-25-20-10-8-6-5-7-9-17(20)16-19(22(25)27)21(26)23-18-11-14-24(2)15-12-18/h16,18H,3-15H2,1-2H3,(H,23,26)
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147n/an/an/an/an/an/an/an/a



Shionogi Pharmaceutical Research Center

Curated by ChEMBL


Assay Description
Displacement of [3H]-CP-55,940 from human CB2 receptor expressed in CHO cell membranes


Bioorg Med Chem 21: 3154-63 (2013)


BindingDB Entry DOI: 10.7270/Q22R3VKX
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50491834
PNG
(CHEMBL2387077)
Show SMILES CCCCn1c2CCOCc2cc(C(=O)NCc2ccccc2)c1=O
Show InChI InChI=1S/C20H24N2O3/c1-2-3-10-22-18-9-11-25-14-16(18)12-17(20(22)24)19(23)21-13-15-7-5-4-6-8-15/h4-8,12H,2-3,9-11,13-14H2,1H3,(H,21,23)
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204n/an/an/an/an/an/an/an/a



Shionogi Pharmaceutical Research Center

Curated by ChEMBL


Assay Description
Displacement of [3H]-CP-55,940 from human CB2 receptor expressed in CHO cell membranes


Bioorg Med Chem 21: 3154-63 (2013)


BindingDB Entry DOI: 10.7270/Q22R3VKX
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50491832
PNG
(CHEMBL2387180)
Show SMILES O=C(NCc1ccccc1)c1cc2CCCCCCc2n(CCCN2CCOCC2)c1=O
Show InChI InChI=1S/C26H35N3O3/c30-25(27-20-21-9-4-3-5-10-21)23-19-22-11-6-1-2-7-12-24(22)29(26(23)31)14-8-13-28-15-17-32-18-16-28/h3-5,9-10,19H,1-2,6-8,11-18,20H2,(H,27,30)
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209n/an/an/an/an/an/an/an/a



Shionogi Pharmaceutical Research Center

Curated by ChEMBL


Assay Description
Displacement of [3H]-CP-55,940 from human CB2 receptor expressed in CHO cell membranes


Bioorg Med Chem 21: 3154-63 (2013)


BindingDB Entry DOI: 10.7270/Q22R3VKX
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50491843
PNG
(CHEMBL2387074)
Show SMILES CCCCn1c(CC)c(C)cc(C(=O)NCc2ccccc2)c1=O
Show InChI InChI=1S/C20H26N2O2/c1-4-6-12-22-18(5-2)15(3)13-17(20(22)24)19(23)21-14-16-10-8-7-9-11-16/h7-11,13H,4-6,12,14H2,1-3H3,(H,21,23)
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322n/an/an/an/an/an/an/an/a



Shionogi Pharmaceutical Research Center

Curated by ChEMBL


Assay Description
Displacement of [3H]-CP-55,940 from human CB1 receptor expressed in CHO cell membranes


Bioorg Med Chem 21: 3154-63 (2013)


BindingDB Entry DOI: 10.7270/Q22R3VKX
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50491831
PNG
(CHEMBL2387182)
Show SMILES CCCCn1c2CCCCCCc2cc(C(=O)NC(C)C)c1=O
Show InChI InChI=1S/C19H30N2O2/c1-4-5-12-21-17-11-9-7-6-8-10-15(17)13-16(19(21)23)18(22)20-14(2)3/h13-14H,4-12H2,1-3H3,(H,20,22)
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591n/an/an/an/an/an/an/an/a



Shionogi Pharmaceutical Research Center

Curated by ChEMBL


Assay Description
Displacement of [3H]-CP-55,940 from human CB1 receptor expressed in CHO cell membranes


Bioorg Med Chem 21: 3154-63 (2013)


BindingDB Entry DOI: 10.7270/Q22R3VKX
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50491836
PNG
(CHEMBL2387073)
Show SMILES CCCCn1c(C)c(C)cc(C(=O)NCc2ccccc2)c1=O
Show InChI InChI=1S/C19H24N2O2/c1-4-5-11-21-15(3)14(2)12-17(19(21)23)18(22)20-13-16-9-7-6-8-10-16/h6-10,12H,4-5,11,13H2,1-3H3,(H,20,22)
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606n/an/an/an/an/an/an/an/a



Shionogi Pharmaceutical Research Center

Curated by ChEMBL


Assay Description
Displacement of [3H]-CP-55,940 from human CB1 receptor expressed in CHO cell membranes


Bioorg Med Chem 21: 3154-63 (2013)


BindingDB Entry DOI: 10.7270/Q22R3VKX
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50491845
PNG
(CHEMBL2387076)
Show SMILES CCCCn1c2CCCCc2cc(C(=O)NCc2ccccc2)c1=O
Show InChI InChI=1S/C21H26N2O2/c1-2-3-13-23-19-12-8-7-11-17(19)14-18(21(23)25)20(24)22-15-16-9-5-4-6-10-16/h4-6,9-10,14H,2-3,7-8,11-13,15H2,1H3,(H,22,24)
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746n/an/an/an/an/an/an/an/a



Shionogi Pharmaceutical Research Center

Curated by ChEMBL


Assay Description
Displacement of [3H]-CP-55,940 from human CB1 receptor expressed in CHO cell membranes


Bioorg Med Chem 21: 3154-63 (2013)


BindingDB Entry DOI: 10.7270/Q22R3VKX
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50491842
PNG
(CHEMBL2387078)
Show SMILES CCCCn1c2CCCCCCc2cc(C(=O)NCc2ccccc2)c1=O
Show InChI InChI=1S/C23H30N2O2/c1-2-3-15-25-21-14-10-5-4-9-13-19(21)16-20(23(25)27)22(26)24-17-18-11-7-6-8-12-18/h6-8,11-12,16H,2-5,9-10,13-15,17H2,1H3,(H,24,26)
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890n/an/an/an/an/an/an/an/a



Shionogi Pharmaceutical Research Center

Curated by ChEMBL


Assay Description
Displacement of [3H]-CP-55,940 from human CB1 receptor expressed in CHO cell membranes


Bioorg Med Chem 21: 3154-63 (2013)


BindingDB Entry DOI: 10.7270/Q22R3VKX
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50491840
PNG
(CHEMBL2387186)
Show SMILES CCCCn1c2CCCCCCc2cc(C(=O)NCCc2ccccc2)c1=O
Show InChI InChI=1S/C24H32N2O2/c1-2-3-17-26-22-14-10-5-4-9-13-20(22)18-21(24(26)28)23(27)25-16-15-19-11-7-6-8-12-19/h6-8,11-12,18H,2-5,9-10,13-17H2,1H3,(H,25,27)
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908n/an/an/an/an/an/an/an/a



Shionogi Pharmaceutical Research Center

Curated by ChEMBL


Assay Description
Displacement of [3H]-CP-55,940 from human CB1 receptor expressed in CHO cell membranes


Bioorg Med Chem 21: 3154-63 (2013)


BindingDB Entry DOI: 10.7270/Q22R3VKX
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50491841
PNG
(CHEMBL2387179)
Show SMILES COCCn1c2CCCCCCc2cc(C(=O)NCc2ccccc2)c1=O
Show InChI InChI=1S/C22H28N2O3/c1-27-14-13-24-20-12-8-3-2-7-11-18(20)15-19(22(24)26)21(25)23-16-17-9-5-4-6-10-17/h4-6,9-10,15H,2-3,7-8,11-14,16H2,1H3,(H,23,25)
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1.77E+3n/an/an/an/an/an/an/an/a



Shionogi Pharmaceutical Research Center

Curated by ChEMBL


Assay Description
Displacement of [3H]-CP-55,940 from human CB1 receptor expressed in CHO cell membranes


Bioorg Med Chem 21: 3154-63 (2013)


BindingDB Entry DOI: 10.7270/Q22R3VKX
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50491844
PNG
(CHEMBL2387181)
Show SMILES CCCCn1c2CCCCCCc2cc(C(N)=O)c1=O
Show InChI InChI=1S/C16H24N2O2/c1-2-3-10-18-14-9-7-5-4-6-8-12(14)11-13(15(17)19)16(18)20/h11H,2-10H2,1H3,(H2,17,19)
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>5.00E+3n/an/an/an/an/an/an/an/a



Shionogi Pharmaceutical Research Center

Curated by ChEMBL


Assay Description
Displacement of [3H]-CP-55,940 from human CB1 receptor expressed in CHO cell membranes


Bioorg Med Chem 21: 3154-63 (2013)


BindingDB Entry DOI: 10.7270/Q22R3VKX
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50491846
PNG
(CHEMBL2387072)
Show SMILES CCCCn1c(C)c(C)cc(NC(=O)Nc2ccccc2)c1=O
Show InChI InChI=1S/C18H23N3O2/c1-4-5-11-21-14(3)13(2)12-16(17(21)22)20-18(23)19-15-9-7-6-8-10-15/h6-10,12H,4-5,11H2,1-3H3,(H2,19,20,23)
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>5.00E+3n/an/an/an/an/an/an/an/a



Shionogi Pharmaceutical Research Center

Curated by ChEMBL


Assay Description
Displacement of [3H]-CP-55,940 from human CB2 receptor expressed in CHO cell membranes


Bioorg Med Chem 21: 3154-63 (2013)


BindingDB Entry DOI: 10.7270/Q22R3VKX
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50491837
PNG
(CHEMBL2387071)
Show SMILES CCCCn1c(C)c(C)cc(NS(=O)(=O)c2ccccc2)c1=O
Show InChI InChI=1S/C17H22N2O3S/c1-4-5-11-19-14(3)13(2)12-16(17(19)20)18-23(21,22)15-9-7-6-8-10-15/h6-10,12,18H,4-5,11H2,1-3H3
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>5.00E+3n/an/an/an/an/an/an/an/a



Shionogi Pharmaceutical Research Center

Curated by ChEMBL


Assay Description
Displacement of [3H]-CP-55,940 from human CB2 receptor expressed in CHO cell membranes


Bioorg Med Chem 21: 3154-63 (2013)


BindingDB Entry DOI: 10.7270/Q22R3VKX
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50491839
PNG
(CHEMBL2387183)
Show SMILES CCCCn1c2CCCCCCc2cc(C(=O)NC2CCCCC2)c1=O
Show InChI InChI=1S/C22H34N2O2/c1-2-3-15-24-20-14-10-5-4-7-11-17(20)16-19(22(24)26)21(25)23-18-12-8-6-9-13-18/h16,18H,2-15H2,1H3,(H,23,25)
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n/an/a<0.200n/an/an/an/an/an/a



Shionogi Pharmaceutical Research Center

Curated by ChEMBL


Assay Description
Agonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production


Bioorg Med Chem 21: 3154-63 (2013)


BindingDB Entry DOI: 10.7270/Q22R3VKX
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50491838
PNG
(CHEMBL2387185)
Show SMILES CCCCn1c2CCCCCCc2cc(C(=O)NC(C)(C)c2ccccc2)c1=O
Show InChI InChI=1S/C25H34N2O2/c1-4-5-17-27-22-16-12-7-6-9-13-19(22)18-21(24(27)29)23(28)26-25(2,3)20-14-10-8-11-15-20/h8,10-11,14-15,18H,4-7,9,12-13,16-17H2,1-3H3,(H,26,28)
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n/an/a 0.200n/an/an/an/an/an/a



Shionogi Pharmaceutical Research Center

Curated by ChEMBL


Assay Description
Agonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production


Bioorg Med Chem 21: 3154-63 (2013)


BindingDB Entry DOI: 10.7270/Q22R3VKX
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50491842
PNG
(CHEMBL2387078)
Show SMILES CCCCn1c2CCCCCCc2cc(C(=O)NCc2ccccc2)c1=O
Show InChI InChI=1S/C23H30N2O2/c1-2-3-15-25-21-14-10-5-4-9-13-19(21)16-20(23(25)27)22(26)24-17-18-11-7-6-8-12-18/h6-8,11-12,16H,2-5,9-10,13-15,17H2,1H3,(H,24,26)
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n/an/a 1.40n/an/an/an/an/an/a



Shionogi Pharmaceutical Research Center

Curated by ChEMBL


Assay Description
Agonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production


Bioorg Med Chem 21: 3154-63 (2013)


BindingDB Entry DOI: 10.7270/Q22R3VKX
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50491840
PNG
(CHEMBL2387186)
Show SMILES CCCCn1c2CCCCCCc2cc(C(=O)NCCc2ccccc2)c1=O
Show InChI InChI=1S/C24H32N2O2/c1-2-3-17-26-22-14-10-5-4-9-13-20(22)18-21(24(26)28)23(27)25-16-15-19-11-7-6-8-12-19/h6-8,11-12,18H,2-5,9-10,13-17H2,1H3,(H,25,27)
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n/an/a 1.70n/an/an/an/an/an/a



Shionogi Pharmaceutical Research Center

Curated by ChEMBL


Assay Description
Agonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production


Bioorg Med Chem 21: 3154-63 (2013)


BindingDB Entry DOI: 10.7270/Q22R3VKX
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50491831
PNG
(CHEMBL2387182)
Show SMILES CCCCn1c2CCCCCCc2cc(C(=O)NC(C)C)c1=O
Show InChI InChI=1S/C19H30N2O2/c1-4-5-12-21-17-11-9-7-6-8-10-15(17)13-16(19(21)23)18(22)20-14(2)3/h13-14H,4-12H2,1-3H3,(H,20,22)
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n/an/a 2.5n/an/an/an/an/an/a



Shionogi Pharmaceutical Research Center

Curated by ChEMBL


Assay Description
Agonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production


Bioorg Med Chem 21: 3154-63 (2013)


BindingDB Entry DOI: 10.7270/Q22R3VKX
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50491845
PNG
(CHEMBL2387076)
Show SMILES CCCCn1c2CCCCc2cc(C(=O)NCc2ccccc2)c1=O
Show InChI InChI=1S/C21H26N2O2/c1-2-3-13-23-19-12-8-7-11-17(19)14-18(21(23)25)20(24)22-15-16-9-5-4-6-10-16/h4-6,9-10,14H,2-3,7-8,11-13,15H2,1H3,(H,22,24)
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n/an/a 17n/an/an/an/an/an/a



Shionogi Pharmaceutical Research Center

Curated by ChEMBL


Assay Description
Agonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production


Bioorg Med Chem 21: 3154-63 (2013)


BindingDB Entry DOI: 10.7270/Q22R3VKX
More data for this
Ligand-Target Pair